Patents by Inventor Curtis C. Harris

Curtis C. Harris has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of diagnosing poor survival prognosis colon cancer using miR-10a
    Patent number: 8343725
    Abstract: The present invention provides novel methods and compositions for the diagnosis and treatment of colon cancers. In particular, the present invention provides diagnostics and prognostics for colon (including colon adenocarcinoma) cancer patients, wherein the methods related to measuring miR levels can predict poor survival. The invention also provides methods of identifying inhibitors of tumorigenesis.
    Type: Grant
    Filed: November 15, 2011
    Date of Patent: January 1, 2013
    Assignees: The Ohio State University Research Foundation, The United States of America, as represented by the Secretary of the Department of Health and Human Services, National Institute of Health, Office of Technology Transfer
    Inventors: Carlo M. Croce, Curtis C. Harris, Aaron J. Schetter
  • Method of diagnosing poor survival prognosis colon cancer using miR-203
    Patent number: 8338105
    Abstract: The present invention provides novel methods and compositions for the diagnosis and treatment of colon cancers. In particular, the present invention provides diagnostics and prognostics for colon (including colon adenocarcinoma) cancer patients, wherein the methods related to measuring miR levels can predict poor survival. The invention also provides methods of identifying inhibitors of tumorigenesis.
    Type: Grant
    Filed: November 15, 2011
    Date of Patent: December 25, 2012
    Assignees: The Ohio State University Research Foundation, The United States of America as represented by the Secretary of the Department of Health and Human Services, National Institute of Health, Office of Technology Tansfer
    Inventors: Carlo M. Croce, Curtis C. Harris, Aaron J. Schetter
  • Method of diagnosing poor survival prognosis colon cancer using miR-103-2
    Patent number: 8338104
    Abstract: The present invention provides novel methods and compositions for the diagnosis and treatment of colon cancers. In particular, the present invention provides diagnostics and prognostics for colon (including colon adenocarcinoma) cancer patients, wherein the methods related to measuring miR levels can predict poor survival. The invention also provides methods of identifying inhibitors of tumorigenesis.
    Type: Grant
    Filed: November 15, 2011
    Date of Patent: December 25, 2012
    Assignees: The Ohio State University Research Foundation, The United States of America, as represented by the Department of Health and Human Services, National Institute of Health, Office of Technology Transfer
    Inventors: Carlo M. Croce, Curtis C. Harris, Aaron J. Schetter
  • Method of diagnosing poor survival prognosis colon cancer using miR-181b
    Patent number: 8338102
    Abstract: The present invention provides novel methods and compositions for the diagnosis and treatment of colon cancers. In particular, the present invention provides diagnostics and prognostics for colon (including colon adenocarcinoma) cancer patients, wherein the methods related to measuring miR levels can predict poor survival. The invention also provides methods of identifying inhibitors of tumorigenesis.
    Type: Grant
    Filed: November 14, 2011
    Date of Patent: December 25, 2012
    Assignees: The Ohio State University Research Foundation, The United States of America, as represented by the Secretary of the Department of Health and Human Services, National Institute of Health, Office of Technology Transfer
    Inventors: Carlo M. Croce, Curtis C. Harris, Aaron J. Schetter
  • Method of diagnosing poor survival prognosis colon cancer using miR-29a
    Patent number: 8338106
    Abstract: The present invention provides novel methods and compositions for the diagnosis and treatment of colon cancers. In particular, the present invention provides diagnostics and prognostics for colon (including colon adenocarcinoma) cancer patients, wherein the methods related to measuring miR levels can predict poor survival. The invention also provides methods of identifying inhibitors of tumorigenesis.
    Type: Grant
    Filed: November 15, 2011
    Date of Patent: December 25, 2012
    Assignees: The Ohio State University Research Foundation, The United States of America, as represented by the Secretary of the Department of Health and Human Services, National Institute of Health, Office of Technology Transfer
    Inventors: Carlo M. Croce, Curtis C. Harris, Aaron J. Schetter
  • Method of diagnosing poor survival prognosis colon cancer using miR-106a
    Patent number: 8338103
    Abstract: The present invention provides novel methods and compositions for the diagnosis and treatment of colon cancers. In particular, the present invention provides diagnostics and prognostics for colon (including colon adenocarcinoma) cancer patients, wherein the methods related to measuring miR levels can predict poor survival. The invention also provides methods of identifying inhibitors of tumorigenesis.
    Type: Grant
    Filed: November 14, 2011
    Date of Patent: December 25, 2012
    Assignees: The Ohio State University Research Foundation, The United States of America, as represented by the Secretary of the Deparment of Health and Human Services, National Institute of Health, Office of Technology Transfer
    Inventors: Carlo M. Croce, Curtis C. Harris, Aaron J. Schetter
  • Tumor suppressor gene p33ING2
    Patent number: 8206937
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of novel human tumor suppressors, antibodies to such tumor suppressors, methods of detecting such nucleic acids and proteins, methods of screening for modulators of tumor suppressors, and methods of diagnosing and treating tumors with such nucleic acids and proteins.
    Type: Grant
    Filed: April 4, 2011
    Date of Patent: June 26, 2012
    Assignee: The United States of America, as represented by the Secretay of the Department of Health and Human Services
    Inventors: Curtis C. Harris, Makoto Nagashima
  • METHOD OF DIAGNOSING POOR SURVIVAL PROGNOSIS COLON CANCER USING miR-103-2
    Publication number: 20120077699
    Abstract: The present invention provides novel methods and compositions for the diagnosis and treatment of colon cancers. In particular, the present invention provides diagnostics and prognostics for colon (including colon adenocarcinoma) cancer patients, wherein the methods related to measuring miR levels can predict poor survival. The invention also provides methods of identifying inhibitors of tumorigenesis.
    Type: Application
    Filed: November 15, 2011
    Publication date: March 29, 2012
    Applicants: Department of Health and Human Services, The Ohio State University Research Foundation
    Inventors: Carlo M. Croce, Curtis C. Harris, Aaron J. Schetter
  • METHOD OF DIAGNOSING POOR SURVIVAL PROGNOSIS COLON CANCER USING miR-29a
    Publication number: 20120077700
    Abstract: The present invention provides novel methods and compositions for the diagnosis and treatment of colon cancers. In particular, the present invention provides diagnostics and prognostics for colon (including colon adenocarcinoma) cancer patients, wherein the methods related to measuring miR levels can predict poor survival. The invention also provides methods of identifying inhibitors of tumorigenesis.
    Type: Application
    Filed: November 15, 2011
    Publication date: March 29, 2012
    Applicants: DEPARTMENT OF HEALTH AND HUMAN SERVICES, THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION
    Inventors: Carlo M. Croce, Curtis C. Harris, Aaron J. Schetter
  • METHOD OF PREDICTING CHEMOTHERAPY EFFECTIVENESS IN COLON ADENOCARCINOMA PATIENTS, USING MIR-21
    Publication number: 20120065098
    Abstract: The present invention provides novel methods and compositions for the diagnosis and treatment of colon cancers. In particular, the present invention provides diagnostics and prognostics for colon (including colon adenocarcinoma) cancer patients, wherein the methods related to measuring miR levels can predict poor survival. The invention also provides methods of identifying inhibitors of tumorigenesis.
    Type: Application
    Filed: November 15, 2011
    Publication date: March 15, 2012
    Applicants: Department of Health and Human Services, The Ohio State University Research Foundation
    Inventors: Carlo M. Croce, Curtis C. Harris, Aaron J. Schetter
  • METHOD OF DIAGNOSING POOR SURVIVAL PROGNOSIS COLON CANCER USING miR-106a
    Publication number: 20120065097
    Abstract: The present invention provides novel methods and compositions for the diagnosis and treatment of colon cancers. In particular, the present invention provides diagnostics and prognostics for colon (including colon adenocarcinoma) cancer patients, wherein the methods related to measuring miR levels can predict poor survival. The invention also provides methods of identifying inhibitors of tumorigenesis.
    Type: Application
    Filed: November 14, 2011
    Publication date: March 15, 2012
    Applicants: DEPARTMENT OF HEALTH AND HUMAN SERVICES, THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION
    Inventors: Carlo M. Croce, Curtis C. Harris, Aaron J. Schetter
  • TUMOR SUPPRESSOR GENE, P47ING3
    Publication number: 20120064524
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of novel human tumor suppressors, antibodies to such tumor suppressors, methods of detecting such nucleic acids and proteins, methods of screening for modulators of tumor suppressors, and methods of diagnosing and treating tumors with such nucleic acids and proteins.
    Type: Application
    Filed: October 11, 2011
    Publication date: March 15, 2012
    Applicant: The Government of the USA as represented by the Secretary of the Dep. of Health and Human Services
    Inventors: Curtis C. Harris, Makoto Nagashima
  • METHOD OF DIAGNOSING POOR SURVIVAL PROGNOSIS COLON CANCER USING miR-203
    Publication number: 20120058914
    Abstract: The present invention provides novel methods and compositions for the diagnosis and treatment of colon cancers. In particular, the present invention provides diagnostics and prognostics for colon (including colon adenocarcinoma) cancer patients, wherein the methods related to measuring miR levels can predict poor survival. The invention also provides methods of identifying inhibitors of tumorigenesis.
    Type: Application
    Filed: November 15, 2011
    Publication date: March 8, 2012
    Applicants: DEPARTMENT OF HEALTH AND HUMAN SERVICES, THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION
    Inventors: Carlo M. Croce, Curtis C. Harris, Aaron J. Schetter
  • METHOD OF DIAGNOSING POOR SURVIVAL PROGNOSIS COLON CANCER USING miR-10a
    Publication number: 20120058915
    Abstract: The present invention provides novel methods and compositions for the diagnosis and treatment of colon cancers. In particular, the present invention provides diagnostics and prognostics for colon (including colon adenocarcinoma) cancer patients, wherein the methods related to measuring miR levels can predict poor survival. The invention also provides methods of identifying inhibitors of tumorigenesis.
    Type: Application
    Filed: November 15, 2011
    Publication date: March 8, 2012
    Applicants: DEPARTMENT OF HEALTH AND HUMAN SERVICES, THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION
    Inventors: Carlo M. Croce, Curtis C. Harris, Aaron J. Schetter
  • METHOD OF DIAGNOSING POOR SURVIVAL PROGNOSIS COLON CANCER USING let-7g
    Publication number: 20120058912
    Abstract: The present invention provides novel methods and compositions for the diagnosis and treatment of colon cancers. In particular, the present invention provides diagnostics and prognostics for colon (including colon adenocarcinoma) cancer patients, wherein the methods related to measuring miR levels can predict poor survival. The invention also provides methods of identifying inhibitors of tumorigenesis.
    Type: Application
    Filed: November 14, 2011
    Publication date: March 8, 2012
    Applicants: DEPARTMENT OF HEALTH AND HUMAN SERVICES, THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION
    Inventors: Carlo M. Croce, Curtis C. Harris, Aaron J. Schetter
  • METHOD OF DIAGNOSING POOR SURVIVAL PROGNOSIS COLON CANCER USING miR-181b
    Publication number: 20120058911
    Abstract: The present invention provides novel methods and compositions for the diagnosis and treatment of colon cancers. In particular, the present invention provides diagnostics and prognostics for colon (including colon adenocarcinoma) cancer patients, wherein the methods related to measuring miR levels can predict poor survival. The invention also provides methods of identifying inhibitors of tumorigenesis.
    Type: Application
    Filed: November 14, 2011
    Publication date: March 8, 2012
    Applicants: DEPARTMENT OF HEALTH AND HUMAN SERVICES, THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION
    Inventors: Carlo M. Croce, Curtis C. Harris, Aaron J. Schetter
  • METHOD OF DIAGNOSING POOR SURVIVAL PROGNOSIS COLON CANCER USING miR-16b
    Publication number: 20120058913
    Abstract: The present invention provides novel methods and compositions for the diagnosis and treatment of colon cancers. In particular, the present invention provides diagnostics and prognostics for colon (including colon adenocarcinoma) cancer patients, wherein the methods related to measuring miR levels can predict poor survival. The invention also provides methods of identifying inhibitors of tumorigenesis.
    Type: Application
    Filed: November 14, 2011
    Publication date: March 8, 2012
    Applicants: DEPARTMENT OF HEALTH AND HUMAN SERVICES, THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION
    Inventors: Carlo M. Croce, Curtis C. Harris, Aaron J. Schetter
  • MicroRNAs in Never-Smokers and Related Materials and Methods
    Publication number: 20120027753
    Abstract: The present invention provides novel methods and compositions for the diagnosis, prognosis and treatment of lung cancer in never-smokers. The invention also provides methods of identifying anti-lung cancer agents.
    Type: Application
    Filed: February 24, 2010
    Publication date: February 2, 2012
    Applicants: THE OHIO STATE UNIVERSITY, Department of Health and Human Sevices
    Inventors: Carlo M. Croce, Curtis C. Harris, Masahiro Seike, Izumi Horikawa
  • POT1 ALTERNATIVE SPLICING VARIANTS
    Publication number: 20120016003
    Abstract: The present invention provides methods and compositions for diagnosis and treatment of carcinomas with aberrant expression patterns of POT 1. The invention also provides methods of identifying compounds that may modulate the cellular expression of POT 1. The invention further provides methods for treating subjects suffering from or at risk of developing a colorectal carcinoma.
    Type: Application
    Filed: February 15, 2011
    Publication date: January 19, 2012
    Applicants: and Human
    Inventors: Qin Yang, Curtis C. Harris
  • Method of diagnosing poor survival prognosis colon cancer using microRNA-21
    Patent number: 8084199
    Abstract: The present invention provides novel methods and compositions for the diagnosis and treatment of colon cancers. The invention also provides methods of identifying inhibitors of tumorigenesis.
    Type: Grant
    Filed: July 12, 2007
    Date of Patent: December 27, 2011
    Assignees: The Ohio State University Research Foundation, The United States of America as represented by the Department of Health and Human Services, National Institutes of Health, Office of Technology Transfer
    Inventors: Carlo M. Croce, Curtis C. Harris, Aaron J. Schetter