Abstract: Systems and processes for operating an intelligent automated assistant are provided. For example, an intelligent automated assistant obtains a static vocabulary entry for an application and registers the static vocabulary entry to a knowledge base. While the application is running, the intelligent automated assistant receives a request from the application to register a dynamic vocabulary entry, and also registers the dynamic vocabulary entry. Upon receiving a user input, the intelligent automated assistant determines whether a matching vocabulary entry for the application has been registered and causes the application to perform a task based on the matching vocabulary entry.

Abstract: A cosmetic part is formed via compression molding in a single molding operation with no post processing by forming an assemblage of feed constituents, wherein the assemblage includes plural fiber-bundle-based preforms and one or more resin-only constituents, the latter configured and positioned as appropriate to create resin-rich cosmetic layers where desired on the part.

Abstract: A method for processing massive fiber bundles includes massive fiber-bundle formation and massive materials handling, wherein plural small-diameter bundles are unified, while more or less preserving their legacy cross-sectional form. It also includes bending, such as to create non-linear preforms, and preform-charge fabrication. Embodiments of the invention operate to help preserve a desired fiber alignment throughout a part fabricated from relatively large-diameter fiber bundles.

Abstract: An in-situ fenestration device including a fenestration catheter extending along a longitudinal axis and a proximal tip extending from the fenestration catheter. The fenestration catheter includes a first articulating element and a second articulating element. The first articulating element is articulable about the longitudinal axis from a delivery state to a deployment state. The second articulating element articulable about the longitudinal axis from the delivery state to the deployment state. The first articulating element and the second articulating element in the deployment state are configured to form a fenestration in a graft material at a fenestration site of a stent graft.

Abstract: An in-situ fenestration device for locating a fenestration site and for forming a fenestration. The in-situ fenestration device includes first and second magnetic locators configured to magnetically mate in a mated position within a vasculature of a patient at the fenestration site. The in-situ fenestration device also includes first and second heating elements configured to heat the first and second magnetic locators to form the fenestration at the fenestration site.

Abstract: The present disclosure provides a method including positioning a first guidewire within a primary guidewire lumen of a multi-lumen tapered tip. A second guidewire is positioned within a secondary guidewire lumen and a shared guidewire lumen of the multi-lumen tapered tip, the second guidewire preventing the first guidewire from entering the shared guidewire lumen. A delivery system including the multi-lumen tapered tip is advanced over the second guidewire. By advancing the delivery system over a single guidewire, any possibility of entanglement of multiple guidewires during advancement of the delivery system is eliminated. The method further includes a guidewire exchange including releasing the second guidewire from the shared guidewire lumen, advancing the first guidewire through and out of the shared guidewire lumen, and advancing the delivery system over the first guidewire to a deployment location.

Abstract: Disclosed herein are techniques for implementing an intelligent assistance (“IA”) or extended intelligence (“EI”) ecosystem for soft tissue luminal applications. In various embodiments, a computing system analyzes first layer input data (indicating movement, position, and/or relative distance for a person(s) and object(s) in a room) and second layer input data. The second layer input data includes sensor and/or imaging data of a patient. Based on the analysis, the computing system generates one or more recommendations for guiding a medical professional in navigating a surgical device(s) with respect to one or more soft tissue luminal portions of the patient. The recommendation(s) include at least one mapped guide toward, in, and/or around the one or more soft tissue luminal portions. The mapped guide can include data corresponding to at least three dimensions, e.g., a 3D image/video. The computing system can present the recommendation(s) as image-based output, using a user experience device.

Abstract: Systems and methods for determining movement of a robot are provided. A computing system of the robot receives information including an initial state of the robot and a goal state of the robot. The computing system determines, using nonlinear optimization, a candidate trajectory for the robot to move from the initial state to the goal state. The computing system determines whether the candidate trajectory is feasible. If the candidate trajectory is feasible, the computing system provides the candidate trajectory to a motion control module of the robot. If the candidate trajectory is not feasible, the computing system determines, using nonlinear optimization, a different candidate trajectory for the robot to move from the initial state to the goal state, the nonlinear optimization using one or more changed parameters.

Abstract: A stent-graft prosthesis includes a graft material having a tubular construction, a frame coupled to the graft material, and a port or opening disposed between a proximal end and a distal end of the graft material. The port or opening is open during deployment of the stent-graft prosthesis to enable blood flow from a graft lumen within the graft material to exit the graft lumen, and the port or opening is blocked upon full deployment of the stent-graft prosthesis to prevent blood flow from within the graft lumen from exiting the graft lumen through the port or opening.

Abstract: The present invention relates to pharmaceutical formulations of a pharmaceutically active antigen binding protein, for example a monoclonal antibody. Such formulations comprise, in addition to the antigen binding protein, a buffering agent and a tonicity agent.

Abstract: A system including one or more memory devices having instructions stored thereon, that, when executed by one or more processors, cause the one or more processors to receive travel data associated with a travel plan of a user indicating one or more travel destinations. The instructions cause the one or more processors to receive destination risk data indicating a destination risk of the one or more travel destinations associated with transmission of an infectious disease, receive personal risk data indicating a risk of the user associated with the infectious disease, and generate an infection travel risk score for the user based on the destination risk data and the personal risk data.

Abstract: A system including one or more memory devices having instructions thereon, that, when executed by one or more processors, cause the one or more processors to receive a request from a service provider to be added to a trusted network of service providers, receive health safety data of a health data stream associated with the service provider and risk data of a risk data stream indicating risk levels associated with the service provider, determine that the service provider meets a level of heath safety by correlating the health safety data of the health data stream with the risk data of the risk data stream, receive a request from a device for a service provider recommendation of the trusted network of service providers, and provide an indication of the service provider to the device in response to a reception of the request for the service provider recommendation.

Abstract: A system including one or more memory devices having instructions stored thereon, that, when executed by one or more processors, cause the one or more processors to receive a request from a user device of a user to add the user to a trusted user service, receive health behavior data of a health behavior data stream associated with behavior relating to a spread of an infectious disease at a physical location, determine whether the user meets one or more health safety levels based on the health behavior data stream, add the user to the trusted user service in response to a determination that the user meets the one or more health safety levels, and generate an access indication for the user to access the physical location at one or more particular times in response to the determination that the user meets the one or more health safety levels.

Abstract: A system including one or more memory devices having instructions thereon, that, when executed by one or more processors, cause the one or more processors to receive a request from a service provider to be added to a trusted network of service providers, receive health safety data of a health data stream associated with the service provider and risk data of a risk data stream indicating risk levels associated with the service provider, determine that the service provider meets a level of heath safety by correlating the health safety data of the health data stream with the risk data of the risk data stream, receive a request from a device for a service provider recommendation of the trusted network of service providers, and provide an indication of the service provider to the device in response to a reception of the request for the service provider recommendation.

Abstract: The present invention relates to pharmaceutical formulations of a pharmaceutically active antigen binding protein, for example a monoclonal antibody. Such formulations comprise, in addition to the antigen binding protein, a buffering agent and a tonicity agent.

Abstract: A system including one or more memory devices having instructions stored thereon, that, when executed by one or more processors, cause the one or more processors to receive travel data associated with a travel plan of a user indicating one or more travel destinations. The instructions cause the one or more processors to receive destination risk data indicating a destination risk of the one or more travel destinations associated with transmission of an infectious disease, receive personal risk data indicating a risk of the user associated with the infectious disease, and generate an infection travel risk score for the user based on the destination risk data and the personal risk data.

Abstract: A cooler insert for placement into a portable hard cooler or ice chest for separating sandwiches, lunch meats, cheese, vegetables, and the like, and drinks from the materials used to cool these items, is described. Many commercially available portable coolers have rectangular-shaped cooling volumes with at least two of the opposing walls forming a horizontal ledge inside the cooling volume parallel to and below the opening thereof upon which the present cooler insert is supported. The present cooler insert includes three adjacent chambers, a first chamber for containing food items to be cooled, a second chamber for containing clean ice for use for cooling drinks; and a third chamber, having cylindrically-shaped compartments tapered toward the bottom, for holding cans or bottles. Bottom portions of the first two chambers may be formed using aluminum or other conductive metal plates covered with plastic, or using uncoated metal plates for improving conduction to the cooler insert from the cooler.

Abstract: This application relates to techniques that adjust the sleep states of a computing device based on proximity detection and predicted user activity. Proximity detection procedures can be used to determine a proximity between the computing device and a remote computing device coupled to the user. Based on these proximity detection procedures, the computing device can either correspondingly increase or decrease the amount power supplied to the various components during either a low-power sleep state or a high-power sleep state. Additionally, historical user activity data gathered on the computing device can be used to predict when the user will likely use the computing device. Based on the gathered historical user activity, deep sleep signals and light sleep signals can be issued at a time when the computing device is placed within a sleep state which can cause it to immediately enter either a low-power sleep state or a high-power sleep state.

Abstract: This application relates to techniques that adjust the sleep states of a computing device based on proximity detection and predicted user activity. Proximity detection procedures can be used to determine a proximity between the computing device and a remote computing device coupled to the user. Based on these proximity detection procedures, the computing device can either correspondingly increase or decrease the amount power supplied to the various components during either a low-power sleep state or a high-power sleep state. Additionally, historical user activity data gathered on the computing device can be used to predict when the user will likely use the computing device. Based on the gathered historical user activity, deep sleep signals and light sleep signals can be issued at a time when the computing device is placed within a sleep state which can cause it to immediately enter either a low-power sleep state or a high-power sleep state.

Abstract: The present invention relates to pharmaceutical formulations of a pharmaceutically active antigen binding protein, for example a monoclonal antibody. Such formulations comprise, in addition to the antigen binding protein, a buffering agent and a tonicity agent.