Abstract: A dibenzylamine compound represented by the formula (1) wherein R1 and R2 are each a C1-6 alkyl group optionally substituted by halogen atoms and the like; R3, R4 and R5 are each a hydrogen atom, a halogen atom and the like, or R3 and R4 may form, together with carbon atoms bonded thereto, a homocyclic or heterocyclic ring optionally having substituent(s); A is —N(R7) (R8) and the like; ring B is an aryl group or a heterocyclic residue; R6 is a hydrogen atom, a halogen atom, a nitro group, a C1-6 alkyl group and the like; n is an integer of 1 to 3, a prodrug thereof and a pharmaceutically acceptable salt thereof show selective and potent CETP inhibitory activity, and therefore, they can be provided as therapeutic or prophylactic agents for hyperlipidemia or arteriosclerosis and the like.

Abstract: Compound (II) is reacted with formate in the presence of an alkali metal alkoxide and the like to give compound (III); then this is reacted with compound (IVa) or compound (IVb) to give compound (V); then this is reacted with compound (VI) to give compound (VII); and then this is deprotected to give compound (I). The present invention provides an industrially advantageous production method of a 4-acetylpyrimidine compound useful as a synthetic intermediate for a pharmaceutical product: wherein X is a methylthio group and the like, R1 is a lower alkyl group and the like, R2 is a lower alkyl group optionally having substituent(s) and the like, M is an alkali metal and X1 is a halogen atom.

Abstract: Compound (II) and compound (III) are reacted to give compound (IVa) and/or compound (IVb); which are/is then reacted with compound (V) to give compound (I). wherein X is a methylthio group and the like, R1 and R2 are each a lower alkyl group optionally having substituent(s), an aryl group optionally having substituent(s) and the like, R3 is a lower alkyl group, R4 is a hydrogen atom, a lower alkyl group optionally having substituent(s) and the like, and Q is a carboxylate group and the like.

Abstract: The recording medium cartridge includes a cartridge case containing a recording medium and a noncontact-type memory having an IC section for storing information and performing signal processing and an antenna section for transmitting and receiving signals. The antenna section of the memory is placed in a region furthest from metallic parts.

Abstract: A magnetic tape cartridge is equipped with a cartridge, a single tape reel, a tape leader pin, and a U-shaped clip. The cartridge case is formed by fastening upper and lower cases of synthetic resin together and has a tape leader opening formed in the upper and lower side walls of the upper and lower cases. The single tape reel has magnetic tape wound thereon and is rotatably housed within the cartridge case. The tape leader pin is firmly attached to a leading end of the magnetic tape, and is detachably held in an upright state between the upper and lower cases so that it faces the tape leader opening. The U-shaped clip is attached to walls near the tape leader opening to fasten the upper and lower cases together, whereby the fastening strength of the upper and lower cases is enhanced.

Abstract: There is provided methods for producing nateglinide crystals, which comprises the steps of adding an acid(s) to a reaction mixture containing nateglinide to make it acidic, the reaction mixture being obtained by reacting trans-4-isopropylcyclohexylcarbonyl chloride with D-phenylalanine in a mixed solvent of ketone solvent and water in the presence of an alkali; and then adjusting the temperature of the mixture to 58° C. to 72° C. and the concentration of ketone solvent to more than 8 wt % and less than 22 wt % to conduct precipitation of nateglinide crystals. This producing method is the industrially beneficial methods for crystallization of nateglinide.

Abstract: The object of the present invention is to provide a polycarbonate resin composition which has excellent transparency and durability against molding heat, which gives a molded article having an excellent mold release property, reduced strains, improved cracking resistance and, preferably, weatherability, and which is particularly suitable for a transparent member for a vehicle, pellets thereof and a molded article thereof, and the present invention provides a polycarbonate resin composition obtained by blending 100 parts by weight of a polycarbonate resin (Component A) and 0.005 to 2 parts by weight of a full ester (Component B) from an aliphatic polyhydric alcohol having 4 to 8 hydroxyl groups and 5 to 30 carbon atoms and an aliphatic carboxylic acid having 10 to 22 carbon atoms, said Component B having a 5% weight loss temperature, measured by TGA (thermogravimetric analysis), of 250 to 360° C. and having an acid value of 4 to 20, pellets thereof and a molded article thereof.

Abstract: There is provided methods for producing nateglinide crystals, which comprises the steps of adding an acid(s) to a reaction mixture containing nateglinide to make it acidic, the reaction mixture being obtained by reacting trans-4-isopropylcyclohexylcarbonyl chloride with D-phenylalanine in a mixed solvent of ketone solvent and water in the presence of an alkali; and then adjusting the temperature of the mixture to 58° C. to 72° C. and the concentration of ketone solvent to more than 8 wt % and less than 22 wt % to conduct precipitation of nateglinide crystals. This producing method is the industrially beneficial methods for crystallization of nateglinide.

Abstract: The present invention provides a diagnostic apparatus for an evaporative emission control system which can accurately execute leak diagnosis under a stable condition. An ECU clocks a time td2 until the internal pressure value Pte of the evaporative emission control system sealed at the negative pressure reaches the target internal pressure value Pd, sets the pressure change measuring time te2 based on the clocking time td2, and measures the pressure change amount P1 which varies after the internal pressure value Pte of the evaporative emission control system reaches the target internal pressure value Pd for a pressure change measuring time te2. Then, the ECU sets the determination value Pth0 based at least on the spatial capacity of the evaporative emission control system, and determines whether the evaporative emission control system is normal or abnormal based on the pressure change amount P1.

Abstract: The present invention provides a method for industrially producing an optically active lysine derivative useful as a pharmaceutical intermediate. More particularly, the present invention provides a production method including protecting an amino group or an amino group and carboxyl group of optically active 2-amino-6-methyl-6-nitroheptanoic acid with a protecting group, reducing a nitro group to synthesize a 6,6-dimethyl lysine derivative and reacting the 6,6-dimethyl lysine derivative with an acetic acid derivative.

Abstract: A polycarbonate resin composition comprising 100 parts by weight of a polycarbonate resin (component A), 0.01 to 10 parts by weight of at least one ultraviolet light absorber (component B) selected from the group of a specific cyclic imino ester, and 0.01 to 1 part by weight of a fatty acid ester compound (component C) which is an ester of a polyhydric alcohol and an aliphatic carboxylic acid and has a molecular weight of 500 to 2,000 g/mol, as well as molded articles thereof. The polycarbonate resin composition provides molded articles having excellent transparency, color and resistance to ultraviolet radiation, is excellent in heat stability at the time of molding and releasability and fully suppresses the production of a deposit on a metal mold.

Abstract: ingle reel with magnetic tape wound thereon is housed in a case. A restraining member, for restricting rotation of the reel by moving toward or away from the reel, is urged in a restraining direction by an urging member. The pushing-up portions of a releasing member are inserted into the through holes bored in the reel gear of the reel 2 so that the lower ends can abut a driving gear. The releasing member moves the restraining member in a releasing direction by moving according to the chucking operation of drive-side rotation drive. A method for manufacturing the reel includes molding a metal reel plate on a bottom surface thereof by insert molding by use of a metal mold in which a hold member for holding an inner peripheral surface of the reel plate is disposed on an outer periphery of a gate.

Abstract: The recording medium cartridge includes a cartridge case containing a recording medium and a noncontact-type memory having an IC section for storing information and performing signal processing and an antenna section for transmitting and receiving signals. In one cartridge, the antenna section of the memory is placed in a region furtherest from metallic parts. In other cartridge, the memory is mounted in an accommodation portion recessed one step relative to a surrounding portion, in such a way that a portion of an inner wall of a real area for accommodating a magnetic tape corresponding to the recording medium is formed, in such a position as to be exposed when the cartridge is loaded into a drive, or in recess formed in an outer surface of a case. The cartridge label is attached to the cartridge and contains the noncontact-type memory.

Abstract: The present invention relates to a method of inhibiting lipid absorption through the small intestine, which comprises administering a compound having a CETP inhibitory activity to an administration subject, and an inhibitor of lipid absorption through the small intestine characterized in that it comprises a compound having a CETP inhibitory activity as an active ingredient. The lipid absorption inhibitor of the present invention can prevent and/or treat diseases such as for example hyperlipidemia, arteriosclerosis, coronary artery diseases, obesity, diabetes, hypertension and metabolic syndrome by inhibiting lipid absorption through the small intestine.

Abstract: Compound (I) is reacted with compound (II) to give compound (III), which is then reacted with compound (IX) to give compound (VIII), which is then preferably deprotected by an enzyme reaction to give compound (XII). The present invention provides an advantageous process for preparing a pyrimidine derivative useful as an enzyme inhibitor, and a synthetic intermediate: wherein P is an alkyl group and the like, R1 and R2 are alkyl groups and the like, R3 is an alkyl group optionally having substituent(s) and the like, R4 is a hydrogen atom and the like, R5 is an aralkyl group optionally having substituent(s) and the like, and Y is a heteroaryl group optionally having substituent(s) and the like.

Abstract: A magnetic tape cartridge has a case including a datum hole into which a positioning pin is inserted at a predetermined position thereof; a reel rotatably supported on the case with a magnetic tape wound thereon and including an engaging gear formed in the outer periphery of the flange thereof; a rotation restricting mechanism disposed in the case and engaging with the engaging gear of the reel to thereby restrict the rotation of the reel; and, an engagement releasing element slidably inserted into the datum hole from inside the case and removing the engagement between the rotation restricting mechanism and the engaging gear through the sliding movement thereof within the datum hole, wherein the positioning pin is inserted into the datum hole from outside of the case and push and slide the engagement releasing element, thereby releasing the rotation restriction of the reel by the rotation restricting mechanism.

Abstract: A speaker device includes a first cabinet on which a speaker unit is mounted, a second cabinet which is engaged with the first cabinet, and a logo-mark printed panel and a metal attaching side panel mounted on a one side surface or other side surface opposite to the one side surface of a cabinet manufactured when the first cabinet and the second cabinet are engaged. Particularly, in the speaker device, the one side surface of the cabinet is formed into the same shape as the other side surface of the cabinet, and the logo-mark printed panel and the metal attaching side panel are formed into shapes to be engaged with the one side surface and the other side surface, respectively.