Abstract: A paper winding machine is provided. The paper winding machine includes a frame body, wherein a winding roller is installed on the frame body in a horizontal direction, two winding roller adjusting mechanisms are respectively installed at two ends of and inside the winding roller, one end of the winding roller is connected with one end of a first rotating shaft, the other end of the winding roller is connected with one end of a second rotating shaft, the other end of the first rotating shaft and the other end of the second rotating shaft are installed on the frame body via bearing seats respectively, a crank handle is provided at the other end of the first rotating shaft, and a through groove is formed in an outer wall of the winding roller and formed in a length direction of the winding roller.

Abstract: A recombinant vector of a thermolabile UNG fused protein and an expressing and purifying method are provided. The method comprises cloning a Cod UNG genetic sequence to a pCold-SUMO vector to construct a recombinant vector pCold-SUMO-Cod UNG, transforming to E. coli BL21 (DE3) competent cells, transforming and expressing molecular chaperone plasmids pG-Tf2, and inducing the expression at a low temperature to obtain a soluble SUMO-Cod UNG fused protein.

Abstract: In some aspects, the disclosure relates to compositions and methods of engineering a transgene. In some embodiments, the disclosure provides self-regulating recombinant nucleic acids, viral vectors and pharmaceutical compositions comprising a MeCP2 transgene. In some embodiments, compositions and methods described by the disclosure are useful for treating diseases and disorders associated with a loss of function mutation, for example Rett syndrome.

Abstract: The present disclosure provides a method for obtaining adventitious tetraploid buds of Blumea balsamifera, comprising the following steps: selecting a root segment of diploid B. balsamifera as an explant, culturing the root segment in a chromosome doubling inducing medium supplemented with 0.025-0.1 mg/L 1-naphthaleneacetic acid (NAA), 1.0-2.0 mg/L 6-benzylaminopurine (6-BA), and 90-150 mg/L colchicine, inducing explant cells, and simultaneously doubling chromosomes and differentiating the adventitious buds. The present disclosure fills the blank of using a root of B. balsamifera as the explant and increases effective explant sources during the propagation, proliferation and biotechnological breeding of B. balsamifera. More importantly, root cells of the B.

Abstract: Aspects of the disclosure relate to manufacturing AAV using a stable cell line that expresses the rep gene by engineering tRNA to suppress a mutation introduced to a rep integrated into the genome of the cell line.

Abstract: Provided are a tail point detection method and apparatus, a device, and a storage medium. The implementation scheme includes acquiring a target audio; identifying a sentence pattern type of the target audio; determining detection waiting duration according to the sentence pattern type; and determining a result of detecting a tail point of the target audio according to the detection waiting duration.

Abstract: In some aspects the disclosure provides compositions and methods for promoting expression of functional Forkhead box G1 (FOXG1) protein in a subject. In some embodiments, the disclosure provides methods of treating a subject having FOXG1 deficiency.

Abstract: A device is provided. In some examples, the device includes a radar sensor configured to receive reflected chirps. In addition, the device includes processing circuitry configured to determine that a first object is moving. The processing circuitry is further configured to, responsive to determining that the first object is moving, determine a first location of the first object using a single frame of the reflected chirps. The processing circuitry is also configured to determine that a second object is stationary. In addition, the processing circuitry is configured to, responsive to determining that the second object is stationary, determine a second location of the second object using a plurality of frames of the reflected chirps.

Abstract: This invention provides for a radially expandable stent having superior strength and reduced foreshortening properties. The stents have a mixed configuration of straight and arcuate connector segments that serve to join annular segments that make up the body of the stent. Surprisingly the described mixed configuration provides superior resistance to flip deformation while maintaining desired flexibility.

Abstract: A millimeter or mm-wave system includes transmission of a millimeter wave (mm-wave) radar signal by a transmitter to an object. The transmitted mm-wave radar signal may include at least two signal orientations, and in response to each signal orientation, the object reflects corresponding signal reflections. The signal reflections are detected and a determination is made as to location of the object.

Abstract: The present disclosure provides an organic light-emitting diode structure and a display device. The electron blocking layer, the luminescent layer and the hole blocking layer in the organic light-emitting diode structure satisfy: HOMOhost?HOMOEBL?0.3 eV, LUMOhost>LUMOHBL, and HOMOHBL?HOMOhost?0.1 eV, wherein HOMO is the highest occupied molecular orbital, LUMO is the lowest unoccupied molecular orbital, host refers to the host material, EBL refers to the electron blocking layer, and HBL refers to the hole blocking layer.

Abstract: A low latency retimer and a low latency control method are provided; a physical layer module is provided on each of two opposite sides of the retimer; each physical layer module includes at least one set of signal transceiver units including a signal receiving unit and a signal transmitting unit; the signal receiving unit performs a serial-to-parallel conversion on a first high-speed serial signal to generate a parallel signal, and sends the parallel signal to the signal transmitting unit; the signal transmitting unit performs a parallel-to-serial conversion on the parallel signal, to convert the parallel signal to obtain a second high-speed serial signal, and outputs the second high-speed serial signal. Data paths of the retimer form a loopback structure, and the signal transmitting unit and the signal receiving unit are physically adjacent to each other, which solves the problem of signal transmission delay, and avoids high power consumption.

Abstract: A method of coating a substrate, the method comprises adding a nanocarbon material to an electrophoretic solution in an electrophoretic deposition apparatus including the substrate and an electrode spaced from the substrate, and applying a current to the substrate and the electrode to deposit the nanocarbon material onto the substrate.

Abstract: Aspects of the disclosure relate to compositions and methods for exon replacement in a cell or a subject. In some embodiments, the disclosure relates to isolated nucleic acids (and vectors, such as rAAV vectors) encoding one or more guideRNAs (gRNAs) that target an intron-exon boundary; an intronic sequence having a splice signal; and a donor sequence encoding a gene product of a gene of interest, or portion thereof. In some embodiments, compositions described herein are useful for replacing mutant exons associated with certain diseases, for example Duchen's muscular dystrophy (DMD), cystic fibrosis (CF), spinal muscular atrophy (SMA), Rett syndrome, and mucopolysaccharidosis (MPS).

Abstract: An electronic device and one or more control methods thereof are provided. In one example, the electronic device may include a display device, one or more imaging devices, and a signal processing device. The display device may include a display panel and a non-display area at an edge of the display panel, the non-display area having one or more light-passing structures. Each of the one or more imaging devices may correspond to one of the one or more light-passing structures. Further, each of the one or more imaging devices may be disposed in an internal space of the electronic device. The signal processing device may be connected to each of the display device and the one or more imaging devices. The electronic device may increase an actual screen ratio of a rectangular image displayed on a user-oriented side of the electronic device.

Abstract: A power load data prediction method and device, and a storage medium are disclosed. In an embodiment, the he method comprises: acquiring historical power load data of a one-dimensional time sequence, the historical power load data including values of corresponding time points; mapping the values of corresponding time points to a coordinate system in which a horizontal axis is a set time period, and a vertical axis is time points within the time period, and performing marking at each mapping point by using predetermined pixel values corresponding to the values to obtain a mapping image, wherein different values correspond to different pixel values; and inputting the pixel values of the mapping image to a trained data prediction model, and acquiring a power load data prediction value output by the data prediction model. The method and device and the storage medium can improve the prediction accuracy of the power load data.

Abstract: Provided is an electroluminescent device, including an anode, a cathode, and a light emitting layer disposed between the anode and the cathode, wherein the light emitting layer includes a host material and a dopant material; the host material includes a component A and a component B; the component A and the component B have the following general structural formula: wherein n is a positive integer greater than or equal to 1; and Ar is any one of the following structures:

Abstract: Aspects of the disclosure relate to compositions and methods for treating certain diseases associated with the presence of one or more premature stop codons in a gene, for example dominantly inherited diseases or recessively inherited diseases. In some embodiments, compositions comprise a vector (e.g., a viral vector, such as an rAAV vector) encoding one or more synthetic suppressor transfer RNAs (tRNAs) configured to read-through certain stop codons (e.g., premature stop codons). In some embodiments, the disclosure relates to methods for treating Hurler syndrome comprising administering such vectors to a subject.

Abstract: A system may include a cluster and a module of the cluster. The module may include a user resource definition and a catalog server. The catalog server may maintain a configuration of the cluster.

Abstract: In an example, a method is implemented in a radar system. The method may include transmitting, via transmission channels, a frame of chirps, the chirps transmitted having a programmed frequency offset that is a function of a transmission channel of the transmission channels that is transmitting the frame of chirps, receiving, via a receive channel, a frame of reflected chirps, the reflected chirps comprising the chirps reflected by an object within a field of view of the radar system, and determining a Doppler domain representation of the frame of reflected chirps having a Doppler domain spectrum that includes multiple spectrum bands, the object represented in at least a portion of the spectrum bands based on the reflected chirps, wherein the programmed frequency is configured to cause the Doppler domain spectrum to include a number of spectrum bands greater than the number of transmission channels.