Abstract: A new class of rapamycin 40-O-cyclic hydrocarbon esters is disclosed. The 40-O position of the rapamycin ester has the form 40-O—R, where R is C(O)—(CH2)n—X, n is 0, 1 or 2, and X is a cyclic hydrocarbon having 3-8 carbons, optionally containing one or more unsaturated bonds, and one or more linear (CH2)n) and/or cyclic (X) carbon atoms may have an OH or halide group. Also disclosed are therapeutic compositions and methods that employ the novel analogs.

Abstract: Status of a payload and a shipping container is tracked and monitored by a tracking module which receives at least one signal from one or more sensors; determines a rate of change over time for the signal(s) and sensor(s); compares, in real-time, memory-stored rate-of-change thresholds corresponding to a payload type to the determined rate(s) of change; and, responsive to the comparison indicating a current or impending violation of a payload handling condition, powers up a wireless communications interface, communicates a digital report to a remote computing system, and powers down the wireless communications interface upon completion of the communicating of the report, while continuing to monitor the sensor(s).

Abstract: Exemplified systems and methods facilitate multicasting latency optimization operations for router, switches, and other network devices, for routed Layer-3 multicast packets to provide even distribution latency and/or selective prioritized distribution of latency among multicast destinations. A list of network destinations for serially-replicated packets is traversed in different sequences from one packet to the next, to provide delay fairness among the listed destinations. The list of network destinations are mapped to physical network ports, virtual ports, or logical ports of the router, switches, or other network devices and, thus, the different sequences are also traversed from these physical network ports, virtual ports, or logical ports. The exemplified systems and methods facilitates the management of traffic that is particularly beneficial in in a data center.

Abstract: An acoustic receiver and method for acoustic logging. The acoustic receiver comprises a housing and a sensor subassembly, which is located within the housing. The sensor subassembly comprises a mount and a cylindrical piezoelectric crystal coupled to the mount. The sensor subassembly also comprises an isolation ring positioned between one of the ends of the cylindrical piezoelectric crystal and the mount. The isolation ring directly engages the crystal and the mount. The method of acoustic logging comprises receiving an acoustic signal using an acoustic receiver, which comprises a cylindrical piezoelectric crystal coupled to a mount without an adhesive material. The method also comprises converting the acoustic signal into an electrical signal by the cylindrical piezoelectric crystal and transmitting the electrical signal to a processor via a conductor coupled to the cylindrical piezoelectric crystal.

Abstract: A new class of rapamycin 40-O-cyclic hydrocarbon esters is disclosed. The 40-O position of the rapamycin ester has the form 40-O—R, where R is C(O)—(CH2)n—X, n is 0, 1 or 2, and X is a cyclic hydrocarbon having 3-8 carbons, optionally containing one or more unsaturated bonds, and one or more linear (CH2)n) and/or cyclic (X) carbon atoms may have an OH or halide group. Also disclosed are therapeutic compositions and methods that employ the novel analogs.

Abstract: A method is provided. An actual fatigue curve limit is determined for actual stress of a drilling component based on an actual yield strength of a material of the drilling component. A plurality of drilling parameters is simulated for the drilling component to determine one or more estimated stresses enacted on the drilling component for one or more combinations of the plurality of drilling parameters. A component life cycle of the drilling component is determined based on the actual fatigue curve limit and the plurality of drilling parameters. A consumed component life of the drilling component is determined for an actual drilling step utilizing the drilling component, and a remaining life of the drilling component after the actual drilling step is determined.

Abstract: A method of recommending a seat to a first user is provided. The method comprising: receiving environmental parameter preferences from a first user device; receiving environmental parameters for one or more seat locations, the one or more seat locations including a first seat location and a second seat location; determining one or more seat location recommendations in response to the environmental parameter preferences and the environmental parameters, the one or more seat location recommendations including a first seat location recommendation identifying the second seat location; and transmitting the one or more seat location recommendations to the first user device.

Abstract: A method of scheduling a meeting room is provided. The method comprising: receiving an attendee list including one or more attendees; obtaining an attendee detail for each attendee in response to the attendee list; determining a weighted ranking for each attendee in response to the attendee detail; obtaining an attendee schedule for each attendee; determining one or more optimal meeting times in response to the attendee schedule; determining a position for each attendee prior to each of the optimal meeting times; determining an optimal meeting location for each optimal meeting time in response to the weighted ranking for each attendee and the position for each attendee; obtaining a meeting room schedule for one or more meeting rooms located within a selected distance of the optimal meeting location at each optimal meeting time; and reserving one of the meeting rooms.

Abstract: The method for drawing a fiber with a textured surface comprises the following steps: —forming of a preform from which the fiber is to be drawn with a textured surface; —addition of an outer layer to the textured preform to preserve the shape of the texture of the preform surface during the drawing operation; —drawing of a fiber from the preform, whereby the fiber keeps the formed texture of the preform surface and —removing the additional outer layer to leave the original surface textured fiber exposed. The obtained fiber can be used as a mold to form a textured hollow channel in another material, as a surface coating and as a pressure detector.

Abstract: Status of a payload and a shipping container is tracked and monitored by a tracking module which receives at least one signal from one or more sensors; determines a rate of change over time for the signal(s) and sensor(s); compares, in real-time, memory-stored rate-of-change thresholds corresponding to a payload type to the determined rate(s) of change; and, responsive to the comparison indicating a current or impending violation of a payload handling condition, powers up a wireless communications interface, communicates a digital report to a remote computing system, and powers down the wireless communications interface upon completion of the communicating of the report, while continuing to monitor the sensor(s).

Abstract: An antenna shield latches around a mandrel or wellbore tubular to protect an antenna carried by the mandrel. The antenna shield opens to facilitate installation over the mandrel, and closes the around the antenna to provide robust protection from the downhole environment. Radial sections of the antenna shield are coupled to one another such that the antenna shield maintains a one piece construction, and the sections may pivot to move the antenna shield between open and closed configurations. Readily opening and closing the antenna shield facilitates maintenance and repair of the antenna and reusability of the antenna shield. Other components of a logging tool system, e.g., stabilizers, may also be provided with a similar latch mechanism for coupling to an outer diameter of the wellbore tubular.

Abstract: A method of indoor environmental preference management includes initializing, by a processor of a preference processing system, a plurality of occupant indoor environmental setting preferences for a plurality of users with a plurality of default settings based on a plurality of control types for a plurality of building systems. The processor of the preference processing system adjusts at least one control setting of the occupant indoor environmental setting preferences for a first user based on feedback from the first user. At least one control device of a building automation system is operated based on the adjustment to the at least one control setting of the occupant indoor environmental setting preferences.

Abstract: A method of integrated environmental control for shared locations includes determining, by a processor of an indoor environment planning system, an occupancy schedule for users scheduled to be at a shared location. The processor of the indoor environment planning system determines a plurality of occupant indoor environmental setting preferences for the users scheduled to be at the shared location based on the occupancy schedule and a weighted set point for a building system operable to adjust an indoor environment at the shared location based on the occupant indoor environmental setting preferences for the users scheduled to be at the shared location. The processor of the indoor environment planning system determines an adjusted set point schedule for the shared location to transition between a previously planned set point and the weighted set point. A control device of the building system is operated based on the adjusted set point schedule.

Abstract: A resistivity logging tool includes a resistivity antenna and an antenna shield having a longitudinal slot segments interconnected to form an elongated slot with an elongated slot length that is longer than the length of the sleeve in which the slot segments are formed thereby enhancing electromagnetic wave strength propagated through the shield. Longitudinal slot segments may be interleaved to maximize the total number of elongated slots.

Abstract: Exemplified systems and methods facilitate multicasting latency shaping operations for router, switches, and other network devices, to control distribution latency and/or selective prioritized distribution of latency among multicast destinations using a tag that specifies a traversal sequence of a Multicast Expansion Table (MET). The exemplified systems and methods facilitates the management of traffic that is particularly beneficial in a data center.

Abstract: A method and system for indoor environmental weighted preference management are provided. The method includes determining, by a processor of a weighted preference processing system, a plurality of occupant indoor environmental setting preferences for a plurality of users at a location and a complaint history of the users. The processor of the weighted preference processing system determines one or more weighted set points for at least one building system operable to adjust an indoor environment at the location based on the occupant indoor environmental setting preferences for the users as weighted with respect to the complaint history of the users. One or more control devices of the at least one building system are operated based on the one or more weighted set points.

Abstract: A method of monitoring a user is provided. The method comprising: receiving a reminder request from a first user device, the reminder request requesting an alarm to activate on the first user device when the first user device is within a selected distance of a second user device; detecting a first current position of the first user device; detecting a second current position of the second user device; determining a distance between the first current position and the second current position; determining whether the distance is less than or equal to the selected distance; and activating an alarm on the first user device when the distance is less than or equal to the selected distance.

Abstract: A method of controlling access to at least one access point along a path is provided. The method comprising: receiving a current position of a user of a user device; checking a schedule of the user of the user device; determining a next event in the schedule; determining an event destination of a next event in the schedule; determining a path from the current position to the event destination; determining an access device list of one or more access devices located on the path; transmitting a command to each access device when the user of the user device is located within a position boundary of the access device; and adjusting the access device when the command is received.

Abstract: A concentrator nozzle attachment for a blower device is disclosed that increases the airflow velocity of the blower without sacrificing the field of the jetting air. The concentrator nozzle is formed of an outer ring with a centrally located guide surface and is placed at the exit of an air tube. As the air exits the air tube, it's forced to flow around the guide surface, thus increasing its velocity. The attachment is secured to the end of the air tube and so does not alter the outer diameter through which the air exits. In this way, air velocity is increased without reducing its effectiveness.

Abstract: An acoustic receiver and method for acoustic logging. The acoustic receiver comprises a housing and a sensor subassembly, which is located within the housing. The sensor subassembly comprises a mount and a cylindrical piezoelectric crystal coupled to the mount. The sensor subassembly also comprises an isolation ring positioned between one of the ends of the cylindrical piezoelectric crystal and the mount. The isolation ring directly engages the crystal and the mount. The method of acoustic logging comprises receiving an acoustic signal using an acoustic receiver, which comprises a cylindrical piezoelectric crystal coupled to a mount without an adhesive material. The method also comprises converting the acoustic signal into an electrical signal by the cylindrical piezoelectric crystal and transmitting the electrical signal to a processor via a conductor coupled to the cylindrical piezoelectric crystal.