Patents by Inventor Daniel A. Crawford

Daniel A. Crawford has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11922631
    Abstract: There is provided a method for generating a 3D physical model of a patient specific anatomic feature from 2D medical images. The 2D medical images are uploaded by an end-user via a Web Application and sent to a server. The server processes the 2D medical images and automatically generates a 3D printable model of a patient specific anatomic feature from the 2D medical images using a segmentation technique. The 3D printable model is 3D printed as a 3D physical model such that it represents a 1:1 scale of the patient specific anatomic feature. The method includes the step of automatically identifying the patient specific anatomic feature.
    Type: Grant
    Filed: July 26, 2023
    Date of Patent: March 5, 2024
    Assignee: Axial Medical Printing Limited
    Inventors: Niall Haslam, Lorenzo Trojan, Daniel Crawford
  • Publication number: 20240018514
    Abstract: The present invention provides methods for large-scale production of a composition enriched for full-length mRNA molecules using an SP6 RNA polymerase and compositions produced using such methods and uses thereof.
    Type: Application
    Filed: December 14, 2022
    Publication date: January 18, 2024
    Inventors: Jonathan Abysalh, Daniel Crawford, Frank DeRosa, Anusha Dias, Michael Heartlein
  • Patent number: 11869670
    Abstract: Systems and methods are provided for multi-schema analysis of patient specific anatomical features from medical images. The system may receive medical images of a patient and metadata associated with the medical images indicative of a selected pathology, and automatically classify the medical images using a segmentation algorithm. The system may use an anatomical feature identification algorithm to identify one or more patient specific anatomical features within the medical images by exploring an anatomical knowledge dataset. A 3D surface mesh model may be generated representing the one or more classified patient specific anatomical features, such that information may be extracted from the 3D surface mesh model based on the selected pathology. Physiological information associated with the selected pathology for the 3D surface mesh model may be generated based on the extracted information.
    Type: Grant
    Filed: April 6, 2023
    Date of Patent: January 9, 2024
    Assignee: Axial Medical Printing Limited
    Inventors: Daniel Crawford, Rory Hanratty, Luke Donnelly, Luis Trindade, Thomas Schwarz, Adam Harpur
  • Publication number: 20230410317
    Abstract: There is provided a method for generating a 3D physical model of a patient specific anatomic feature from 2D medical images. The 2D medical images are uploaded by an end-user via a Web Application and sent to a server. The server processes the 2D medical images and automatically generates a 3D printable model of a patient specific anatomic feature from the 2D medical images using a segmentation technique. The 3D printable model is 3D printed as a 3D physical model such that it represents a 1:1 scale of the patient specific anatomic feature. The method includes the step of automatically identifying the patient specific anatomic feature.
    Type: Application
    Filed: July 26, 2023
    Publication date: December 21, 2023
    Applicant: Axial Medical Printing Limited
    Inventors: Niall HASLAM, Lorenzo TROJAN, Daniel CRAWFORD
  • Publication number: 20230245784
    Abstract: Systems and methods are provided for multi-schema analysis of patient specific anatomical features from medical images. The system may receive medical images of a patient and metadata associated with the medical images indicative of a selected pathology, and automatically classify the medical images using a segmentation algorithm. The system may use an anatomical feature identification algorithm to identify one or more patient specific anatomical features within the medical images by exploring an anatomical knowledge dataset. A 3D surface mesh model may be generated representing the one or more classified patient specific anatomical features, such that information may be extracted from the 3D surface mesh model based on the selected pathology. Physiological information associated with the selected pathology for the 3D surface mesh model may be generated based on the extracted information.
    Type: Application
    Filed: April 6, 2023
    Publication date: August 3, 2023
    Applicant: Axial Medical Printing Limited
    Inventors: Daniel CRAWFORD, Rory HANRATTY, Luke DONNELLY, Luis TRINDADE, Thomas SCHWARZ, Adam HARPUR
  • Patent number: 11715210
    Abstract: There is provided a method for generating a 3D physical model of a patient specific anatomic feature from 2D medical images. The 2D medical images are uploaded by an end-user via a Web Application and sent to a server. The server processes the 2D medical images and automatically generates a 3D printable model of a patient specific anatomic feature from the 2D medical images using a segmentation technique. The 3D printable model is 3D printed as a 3D physical model such that it represents a 1:1 scale of the patient specific anatomic feature. The method includes the step of automatically identifying the patient specific anatomic feature.
    Type: Grant
    Filed: January 4, 2023
    Date of Patent: August 1, 2023
    Assignee: Axial Medical Printing Limited
    Inventors: Niall Haslam, Lorenzo Trojan, Daniel Crawford
  • Publication number: 20230237740
    Abstract: A computer implemented method for generating a 3D printable model of a patient specific anatomic feature from 2D medical images is provided. A 3D image is automatically generated from a set of 2D medical images. A machine learning based image segmentation technique is used to segment the generated 3D image. A 3D printable model of the patient specific anatomic feature is created from the segmented 3D image.
    Type: Application
    Filed: September 4, 2022
    Publication date: July 27, 2023
    Applicant: Axial Medical Printing Limited
    Inventors: Niall HASLAM, Daniel CRAWFORD, Catherine COOMBER
  • Publication number: 20230196563
    Abstract: An image processing method comprising: receiving MRI data representing a scan of an organ of a patient, the MRI data including multiecho data for a plurality of pixels; for each of a plurality of pixels of the MRI data: fitting the multiecho data to a simulated decay curve; calculating a tissue index based on at least one parameter of the simulated decay curve; and comparing the tissue index to a threshold to determine a tissue type; wherein each pixel of the multiecho data consists of 16 or fewer echoes.
    Type: Application
    Filed: April 16, 2021
    Publication date: June 22, 2023
    Inventors: Shonit Punwani, David Atkinson, Yangcan Gong, William Devine, Daniel Crawford Alexander
  • Publication number: 20230141276
    Abstract: There is provided a method for generating a 3D physical model of a patient specific anatomic feature from 2D medical images. The 2D medical images are uploaded by an end-user via a Web Application and sent to a server. The server processes the 2D medical images and automatically generates a 3D printable model of a patient specific anatomic feature from the 2D medical images using a segmentation technique. The 3D printable model is 3D printed as a 3D physical model such that it represents a 1:1 scale of the patient specific anatomic feature. The method includes the step of automatically identifying the patient specific anatomic feature.
    Type: Application
    Filed: January 4, 2023
    Publication date: May 11, 2023
    Applicant: Axial Medical Printing Limited
    Inventors: Niall HASLAM, Lorenzo TROJAN, Daniel CRAWFORD
  • Patent number: 11626212
    Abstract: Systems and methods are provided for multi-schema analysis of patient specific anatomical features from medical images. The system may receive medical images of a patient and metadata associated with the medical images indicative of a selected pathology, and automatically classify the medical images using a segmentation algorithm. The system may use an anatomical feature identification algorithm to identify one or more patient specific anatomical features within the medical images by exploring an anatomical knowledge dataset. A 3D surface mesh model may be generated representing the one or more classified patient specific anatomical features, such that information may be extracted from the 3D surface mesh model based on the selected pathology. Physiological information associated with the selected pathology for the 3D surface mesh model may be generated based on the extracted information.
    Type: Grant
    Filed: May 10, 2022
    Date of Patent: April 11, 2023
    Assignee: Axial Medical Printing Limited
    Inventors: Daniel Crawford, Rory Hanratty, Luke Donnelly, Luis Trindade, Thomas Schwarz, Adam Harpur
  • Publication number: 20230072174
    Abstract: The present disclosure relates generally to devices, systems, and methods for minimally invasive medical treatment, methods of diagnosing and treating diseases, and to visualizing, accessing, and perform interventions involving the thoracic duct.
    Type: Application
    Filed: September 7, 2022
    Publication date: March 9, 2023
    Inventor: Daniel A. Crawford
  • Patent number: 11560562
    Abstract: The present invention provides methods for large-scale production of a composition enriched for full-length mRNA molecules using an SP6 RNA polymerase and compositions produced using such methods and uses thereof.
    Type: Grant
    Filed: February 27, 2018
    Date of Patent: January 24, 2023
    Assignee: Translate Bio, Inc.
    Inventors: Anusha Dias, Daniel Crawford, Frank DeRosa, Jonathan Abysalh, Michael Heartlein
  • Patent number: 11551420
    Abstract: There is provided a method for generating a 3D physical model of a patient specific anatomic feature from 2D medical images. The 2D medical images are uploaded by an end-user via a Web Application and sent to a server. The server processes the 2D medical images and automatically generates a 3D printable model of a patient specific anatomic feature from the 2D medical images using a segmentation technique. The 3D printable model is 3D printed as a 3D physical model such that it represents a 1:1 scale of the patient specific anatomic feature. The method includes the step of automatically identifying the patient specific anatomic feature.
    Type: Grant
    Filed: March 23, 2022
    Date of Patent: January 10, 2023
    Assignee: Axial Medical Printing Limited
    Inventors: Niall Haslam, Lorenzo Trojan, Daniel Crawford
  • Patent number: 11497557
    Abstract: There is provided a method for generating a 3D physical model of a patient specific anatomic feature from 2D medical images. The 2D medical images are uploaded by an end-user via a Web Application and sent to a server. The server processes the 2D medical images and automatically generates a 3D printable model of a patient specific anatomic feature from the 2D medical images using a segmentation technique. The 3D printable model is 3D printed as a 3D physical model such that it represents a 1:1 scale of the patient specific anatomic feature. The method includes the step of automatically identifying the patient specific anatomic feature.
    Type: Grant
    Filed: October 16, 2017
    Date of Patent: November 15, 2022
    Assignee: Axial Medical Printing Limited
    Inventors: Niall Haslam, Lorenzo Trojan, Daniel Crawford
  • Patent number: 11436801
    Abstract: A computer implemented method for generating a 3D printable model of a patient specific anatomic feature from 2D medical images is provided. A 3D image is automatically generated from a set of 2D medical images. A machine learning based image segmentation technique is used to segment the generated 3D image. A 3D printable model of the patient specific anatomic feature is created from the segmented 3D image.
    Type: Grant
    Filed: July 9, 2021
    Date of Patent: September 6, 2022
    Assignee: Axial Medical Printing Limited
    Inventors: Niall Haslam, Daniel Crawford, Catherine Coomber
  • Publication number: 20220270762
    Abstract: Systems and methods are provided for multi-schema analysis of patient specific anatomical features from medical images. The system may receive medical images of a patient and metadata associated with the medical images indicative of a selected pathology, and automatically classify the medical images using a segmentation algorithm. The system may use an anatomical feature identification algorithm to identify one or more patient specific anatomical features within the medical images by exploring an anatomical knowledge dataset. A 3D surface mesh model may be generated representing the one or more classified patient specific anatomical features, such that information may be extracted from the 3D surface mesh model based on the selected pathology. Physiological information associated with the selected pathology for the 3D surface mesh model may be generated based on the extracted information.
    Type: Application
    Filed: May 10, 2022
    Publication date: August 25, 2022
    Applicant: Axial Medical Printing Limited
    Inventors: Daniel CRAWFORD, Rory HANRATTY, Luke DONNELLY, Luis TRINDADE, Thomas SCHWARZ, Adam HARPUR
  • Publication number: 20220215627
    Abstract: There is provided a method for generating a 3D physical model of a patient specific anatomic feature from 2D medical images. The 2D medical images are uploaded by an end-user via a Web Application and sent to a server. The server processes the 2D medical images and automatically generates a 3D printable model of a patient specific anatomic feature from the 2D medical images using a segmentation technique. The 3D printable model is 3D printed as a 3D physical model such that it represents a 1:1 scale of the patient specific anatomic feature. The method includes the step of automatically identifying the patient specific anatomic feature.
    Type: Application
    Filed: March 23, 2022
    Publication date: July 7, 2022
    Applicant: Axial Medical Printing Limited
    Inventors: Niall HASLAM, Lorenzo TROJAN, Daniel CRAWFORD
  • Patent number: 11288865
    Abstract: There is provided a method for generating a 3D physical model of a patient specific anatomic feature from 2D medical images. The 2D medical images are uploaded by an end-user via a Web Application and sent to a server. The server processes the 2D medical images and automatically generates a 3D printable model of a patient specific anatomic feature from the 2D medical images using a segmentation technique. The 3D printable model is 3D printed as a 3D physical model such that it represents a 1:1 scale of the patient specific anatomic feature. The method includes the step of automatically identifying the patient specific anatomic feature.
    Type: Grant
    Filed: September 30, 2021
    Date of Patent: March 29, 2022
    Assignee: Axial Medical Printing Limited
    Inventors: Niall Haslam, Lorenzo Trojan, Daniel Crawford
  • Publication number: 20220073944
    Abstract: The present invention provides, among other things, multimeric coding nucleic acids that exhibit superior stability for in vivo and in vitro use. In some embodiments, a multimeric coding nucleic acid (MCNA) comprises two or more encoding polynucleotides linked via 3? ends such that the multimeric coding nucleic acid compound comprises two or more 5? ends.
    Type: Application
    Filed: August 17, 2021
    Publication date: March 10, 2022
    Inventors: Frank DeRosa, Michael Heartlein, Daniel Crawford, Shrirang Karve
  • Publication number: 20220020213
    Abstract: There is provided a method for generating a 3D physical model of a patient specific anatomic feature from 2D medical images. The 2D medical images are uploaded by an end-user via a Web Application and sent to a server. The server processes the 2D medical images and automatically generates a 3D printable model of a patient specific anatomic feature from the 2D medical images using a segmentation technique. The 3D printable model is 3D printed as a 3D physical model such that it represents a 1:1 scale of the patient specific anatomic feature. The method includes the step of automatically identifying the patient specific anatomic feature.
    Type: Application
    Filed: September 30, 2021
    Publication date: January 20, 2022
    Applicant: Axial Medical Printing Limited
    Inventors: Niall HASLAM, Lorenzo TROJAN, Daniel CRAWFORD