Abstract: Turntable control systems are disclosed. A playback device can include an analog audio source component such as a turntable. The playback device is configured to cause playback of first audio based on analog audio signals generated by the analog audio source component. Based on an indication that analog audio signals are no longer being generated, the playback device requests, via a network interface, audio content from one or more remote computing devices. The request can include identifying related content based on the first audio. The playback device receives, via the network interface, second audio content from, and causes playback of second audio based on the second audio content.

Abstract: Provided herein are methods and compositions for the detection of in-frame deletion germline mutations in the CALR gene. Also provided are methods for determining the prognosis of myeloproliferative diseases and the likelihood of developing somatic mutations in genes involved in the JAK-STAT pathway.

Abstract: Systems and methods for objective assessment of patient response for calibration of therapeutic interventions are pro-vided. Analysis of a human patient's speech provides an objective measurement for pain or discomfort experienced by a patient. This speech analysis can then be used to provide personalized therapeutic interventions which more effectively address the needs of the patient. The speech analysis provides not only a personalized initial intervention, but in the case of ongoing interventions the speech analysis can further refine the intervention as a patient's response changes over time.

Abstract: The present invention provides for single-molecule profiling of combinatorial protein modifications and single-molecule profiling of combinatorial protein modifications combined with single-molecule sequencing of protein/nucleic acids complexes. High-throughput single-molecule imaging was applied to decode combinatorial modifications on millions of individual nucleosomes from pluripotent stem cells and lineage-committed cells. Applicants identified bivalent nucleosomes with concomitant repressive and activating marks, as well as other combinatorial modification states whose prevalence varies with developmental potency. Applying genetic and chemical perturbations of chromatin enzymes show a preferential affect on nucleosomes harboring specific modification states. The present invention also combines this proteomic platform with single-molecule DNA sequencing technology to simultaneously determine the modification states and genomic positions of individual nucleosomes.

Abstract: Disclosed is a method for converting cymene generated from renewable low value terpene streams into renewable benzene, toluene, xylenes, and cymene isomers (ortho and meta) under flow disproportionation reaction conditions, which compounds are basic building blocks for fragrance materials. This technology has potential to replace high volume petrochemical-based feedstocks with plant-based building blocks that can fill the renewability gap for key fragrance ingredients.

Abstract: Examples described herein relate to transitioning a playback session between portable playback devices such as “smart” headphones, earbuds, and handheld speakers with playback devices of a zone-based media playback system. Exemplary techniques facilitate continuity of playback when transitioning between locations (e.g., from at home to on-the-go or vice versa) or between listening paradigms (e.g., personal or out-loud playback of audio content). An example implementation includes detecting a swap trigger, determining the source playback device(s) and target playback device(s), and performing a playback session swap between the source playback device(s) and target playback device(s).

Abstract: Generative media content (e.g., generative audio) can be played back across multiple playback devices concurrently. A generative content group coordinator device can receive input parameters, which can include sensor data, media content, or other such input. The coordinator device can generate first and second generative media content streams, each of which can be transmitted to first and second playback devices, respectively. The first and second playback devices can play back the first and second streams of generative media content concurrently.

Abstract: Disclosed are floating micro-aeration unit (FMU) devices, systems and methods for biological sulfide removal from water/wastewater bodies and streams. In some aspects, a system includes a manifold structure including one or more opening to flow air out of an interior of the manifold structure; one or more support structures connected to the manifold structure, in which the one or more support structures are floatable on a surface of a fluid that includes water or a wastewater; and an air source that flows air to the manifold structure, such that the manifold structure supplies the air containing a predetermined amount of oxygen (e.g., less than 0.1 mg/L of oxygen) to oxidize sulfide of the fluid.

Abstract: An example involves detecting, during a time period by a receiving device, an audio signal comprising a superposition of a plurality of audio signals transmitted by a plurality of respective playback devices. The example further comprises determining a time-frequency representation of the audio signal and obtaining data associating playback devices with respective reference audio signals, each reference audio signal having a predefined time-frequency representation. The example further comprises, based on the time-frequency representation of the audio signal and the data, determining that the audio signal comprises a superposition of a first audio signal transmitted by a first playback device and a second audio signal transmitted by a second playback device.

Abstract: Examples described herein relate to transitioning a playback session between portable playback devices such as “smart” headphones, earbuds, and handheld speakers with playback devices of a zone-based media playback system. Exemplary techniques facilitate continuity of playback when transitioning between locations (e.g., from at home to on-the-go or vice versa) or between listening paradigms (e.g., personal or out-loud playback of audio content). An example implementation includes detecting a swap trigger, determining the source playback device(s) and target playback device(s), and performing a playback session swap between the source playback device(s) and target playback device(s).

Abstract: Disclosed are floating micro-aeration unit (FMU) devices, systems and methods for biological sulfide removal from water/wastewater bodies and streams. In some aspects, a system includes a manifold structure including one or more opening to flow air out of an interior of the manifold structure; one or more support structures connected to the manifold structure, in which the one or more support structures are floatable on a surface of a fluid that includes water or a wastewater; and an air source that flows air to the manifold structure, such that the manifold structure supplies the air containing a predetermined amount of oxygen (e.g., less than 0.1 mg/L of oxygen) to oxidize sulfide of the fluid.

Abstract: A dashboard component assembly for a vehicle, including: a cover-panel; a main body and an auxiliary body, the auxiliary body being retained on the main body so as to be movable in at least one dimension relative to the main body prior to installation of the cover-panel, the cover-panel is configured to cover at least a portion of each of the main body and the auxiliary body; a primary datum included by one of the cover-panel or the main body; a primary datum retainer included by the other of the cover-panel or the main body, the primary datum is configured to engage at least one primary datum retainer to cause a predetermined alignment of the cover-panel with regard to the main body; a secondary datum included by one of the cover-panel or the auxiliary body; a secondary datum receiver comprised by the other of the cover-panel or the auxiliary body.

Abstract: Methods and kits for detecting alternating spatial expression of PTEN and, optionally, SMAD4, CD44, and/or TP53 in colonic tumors are described. The methods and kits are useful for identifying a cancer stem cell (CSC)-like zone within a colonic tumor, identifying an adenoma-adenocarcinoma (Ad-ACA) transition zone in a colorectal cancer (CRC) tumor, identifying a CRC tumor that contains high-grade adenoma and/or early adenocarcinoma regions, identifying CSCs in a CRC tumor, diagnosing a subject with high-grade colon adenoma and/or early adenocarcinoma, and determining the likelihood that a colonic tumor in a subject will undergo invasive transformation if left untreated.

Abstract: A sobriety ignition interlock system including an engine control device and a method for managing available vehicle engine power using the sobriety ignition interlock system. The engine control device includes an engine control processor (ECP) that is electronically connected in between an engine control unit (ECU), an engine sensor assembly, and a sobriety processor. The sobriety processor determines a sobriety level of a vehicle driver and sends a corresponding sobriety signal to the ECP. The ECP intercepts an engine signal transmitted from the engine sensor assembly to the ECU and manipulates the engine signal according to the sobriety signal, in order to manage the available power of the vehicle engine.

Abstract: A sobriety ignition interlock system including an engine control device and a method for managing available vehicle engine power using the sobriety ignition interlock system. The engine control device includes an engine control processor (ECP) that is electronically connected in between an engine control unit (ECU), an engine sensor assembly, and a sobriety processor. The sobriety processor determines a sobriety level of a vehicle driver and sends a corresponding sobriety signal to the ECP. The ECP intercepts an engine signal transmitted from the engine sensor assembly to the ECU and manipulates the engine signal according to the sobriety signal, in order to manage the available power of the vehicle engine.

Abstract: The present invention relates to a method of triggering an event. The method includes receiving a signal stream, detecting a trigger point within the signal stream using a fingerprint associated with the trigger point and triggering an event associated with the detected trigger point.

Abstract: Embodiments described herein relate to a system and method for germicidally irradiating a waste receptacle or other receptacle that fosters microbial growth. A system for treating a waste receptacle may include a housing; a power source disposed about the housing for providing power; and a germicidal source energetically coupled to the power source for irradiating the waste receptacle. The waste receptacle may be a garbage disposal. The germicidal source may be an ultraviolet lamp. A method for treating a waste receptacle may include providing a housing; providing a power source disposed about the housing for providing power; and providing a germicidal lamp energetically coupled to the power source for irradiating the waste receptacle.

Abstract: Methods and kits for detecting alternating spatial expression of PTEN and, optionally, SMAD4, CD44, and/or TP53 in colonic tumors are described. The methods and kits are useful for identifying a cancer stem cell (CSC)-like zone within a colonic tumor, identifying an adenoma-adenocarcinoma (Ad-ACA) transition zone in a colorectal cancer (CRC) tumor, identifying a CRC tumor that contains high-grade adenoma and/or early adenocarcinoma regions, identifying CSCs in a CRC tumor, diagnosing a subject with high-grade colon adenoma and/or early adenocarcinoma, and determining the likelihood that a colonic tumor in a subject will undergo invasive transformation if left untreated.

Abstract: Examples described herein relate to transitioning a playback session between portable playback devices such as “smart” headphones, earbuds, and handheld speakers with playback devices of a zone-based media playback system. Exemplary techniques facilitate continuity of playback when transitioning between locations (e.g., from at home to on-the-go or vice versa) or between listening paradigms (e.g., personal or out-loud playback of audio content). An example implementation includes detecting a swap trigger, determining the source playback device(s) and target playback device(s), and performing a playback session swap between the source playback device(s) and target playback device(s).