Abstract: Systems and methods are provided for intermittent microinfusion. A system may include a pump and an IV set that includes a y-port valve disposed below a pump interface portion of the IV tubing. The y-port valve may include an internal valve member that allows fluid to flow from the pump to a patient when no syringe is attached to the y-port. The internal valve member may be moved by the attachment of a syringe containing the medication to be infused to the y-port such that the fluid pathway from the pump to the patient is blocked and fluid from the syringe can be injected into the IV tubing between the y-port valve and the pump. The pump may retrograde pump the medication into the tubing via the y-port valve and then forward pump the medication to the patient when the syringe is removed from the y-port.

Abstract: An intravenous infusion tubing fitment comprises a body, a rotatable knob coupled with the body, and a pressure dome seated within the knob. The body defines; a first inlet configured for coupling with a first segment of tubing; a first outlet into a pressure dome; a second inlet from the pressure dome; and a second outlet configured for coupling with a second segment of tubing. The knob defines an expansion opening within a surface of the knob. The pressure dome is formed of a flexible elastomeric material and defines a fluid flow path between the first outlet and the second inlet. The pressure dome includes a vane configured to variably regulate flow through the fluid flow path in response to rotation of the knob. The pressure dome is configured to expand through the expansion opening in response to fluid pressure in the fluid flow path.

Abstract: A pump cassette body for detecting air bubbles in a fluid pathway, comprises an upstanding flow director vane, a fitment integrally molded into the pump cassette body, wherein the fitment comprises a base integrally molded into the pump cassette body, an elastomeric member attached to the base, and a housing at least partially surrounding the elastomeric member, wherein the elastomeric member is co-molded to the housing.

Abstract: Pump cassettes, infusion systems, and methods are described. An example pump cassette may include a rigid body comprising a frame portion, a base portion, a compliant membrane disposed substantially therebetween, and two opposing longitudinal edge sections. The rigid body may include a controllable fluid pathway defined in part by the compliant membrane and extending from an inlet port to an outlet port. The pump cassette may include a piston disposed at least partially within the rigid body such that movement of the piston varies a volume of a pump chamber defined within the controllable fluid pathway.

Abstract: Pump cassettes, infusion systems, and methods are described. An example pump cassette may include a rigid body comprising a frame portion, a base portion, a compliant membrane disposed substantially therebetween, and two opposing longitudinal edge sections. The rigid body may include a controllable fluid pathway defined in part by the compliant membrane and extending from an inlet port to an outlet port. The pump cassette may include a slider coupled to the two opposing longitudinal edge sections and longitudinally articulable with respect to the rigid body.

Abstract: Pump cassettes, infusion systems, and methods are described. An example pump cassette may include a rigid body including two opposing edge sections, an inlet port, an outlet port, and a controllable fluid pathway extending from the inlet port to the outlet port. The pump may include a slider coupled to the two opposing edge sections and articulable with respect to the rigid body; and a flow stop valve operably coupled to the controllable fluid pathway.

Abstract: A pressure-maintaining valve assembly can be coupled to the tubing of an infusion pump system. The valve assembly includes an element that regulates fluid flow through the tubing. This element may also act as a one way or check valve.

Abstract: A pumping mechanism is disclosed that includes a plurality of peristaltic pumping actuators configured to selectively and sequentially compress adjacent portions of a first portion of an at least partially compressible pumping element having an inlet that is upstream of an outlet. The plurality of pumping actuators are further configured to reciprocate at a common drive frequency with a first phase offset between each adjacent pair of pumping actuators. The pumping mechanism also includes at least one compensation actuator arranged to selectively compress a second portion of the at least partially compressible pumping element that is disposed between the first portion and the outlet. The at least one compensation actuator is configured to reciprocate at an optimal displacement and at a modulation frequency that is an integer multiple of the fundamental drive frequency and with a second phase offset between the at least one compensation actuator and the adjacent pumping actuator.

Abstract: A pumping mechanism is disclosed that includes a plurality of peristaltic pumping actuators configured to selectively and sequentially compress adjacent portions of a first portion of an at least partially compressible pumping element having an inlet that is upstream of an outlet. The plurality of pumping actuators are further configured to reciprocate at a common drive frequency with a first phase offset between each adjacent pair of pumping actuators. The pumping mechanism also includes at least one compensation actuator arranged to selectively compress a second portion of the at least partially compressible pumping element that is disposed between the first portion and the outlet. The at least one compensation actuator is configured to reciprocate at an optimal displacement and at a modulation frequency that is an integer multiple of the fundamental drive frequency and with a second phase offset between the at least one compensation actuator and the adjacent pumping actuator.

Abstract: A valve for controlling delivery of fluid includes a valve seat comprising a fluid inlet, a fluid outlet and a conical well having an opening, a beveled surface and a bottom, and a valve membrane comprising a conical portion having a base and a tip. The conical portion is configured to fit within the conical well of the valve seat. The valve membrane is configured to fluidly connect the fluid inlet to the fluid outlet when the valve membrane is in an undeformed position and fluidly disconnect the fluid inlet from the fluid outlet when the valve membrane is in a radially deformed position.

Abstract: A valve for controlling delivery of fluid includes a valve seat comprising a fluid inlet, a fluid outlet and a conical well having an opening, a beveled surface and a bottom, and a valve membrane comprising a conical portion having a base and a tip. The conical portion is configured to fit within the conical well of the valve seat. The valve membrane is configured to fluidly connect the fluid inlet to the fluid outlet when the valve membrane is in an undeformed position and fluidly disconnect the fluid inlet from the fluid outlet when the valve membrane is in a radially deformed position.

Abstract: A cassette has an interface element having a first position and a second position. The interface element is configured to be driven from the first position to the second position and back to the first position by unidirectional rotary motion of a driving element. The cassette also has a first and a second pumping chamber each having a volume and each coupled to the interface element such that the volume of the first pumping chamber is increasing while the volume of the second pumping chamber is decreasing as the interface element moves from the first position to the second position and the volume of the first pumping chamber is decreasing while the volume of the second pumping chamber is increasing as the interface element moves from the second position to the first position.

Abstract: A pressure-maintaining valve assembly can be coupled to the tubing of an infusion pump system. The valve assembly includes an element that regulates fluid flow through the tubing. This element may also act as a one way or check valve.

Abstract: A pump cassette includes fluid lumen adapted for passage of an infusion fluid toward a patient. A rotary valve assembly can be actuated to regulate fluid flow through the fluid lumen and a frame is coupled to the fluid lumen and the valve assembly. The frame is adapted to be inserted into a seat of a pump device, wherein the frame provides a platen relative to the fluid lumen. The frame is configured to be inserted into the seat only when aligned in a predetermined orientation relative to the seat.

Abstract: A pumping mechanism includes a housing containing the pumping mechanism, the housing defining a seat configured to receive a pump cassette having a fluid lumen that can be acted upon by the pumping mechanism so as to pump fluid through the fluid lumen of the pump cassette. A platen pad is movably attached to the housing mechanism, wherein the platen pad can movably adjust in position relative to the pump cassette as the pump cassette is secured in the seat of the housing.

Abstract: A pump device includes a pumping mechanism and a housing containing the pumping mechanism. A structure on a door of the housing is configured to urge the tube of a pump set toward engagement with a sensor as the door is closed with the pump set is mounted housing.

Abstract: An intravenous infusion tubing fitment comprises a body, a rotatable knob coupled with the body, and a pressure dome seated within the knob. The body defines; a first inlet configured for coupling with a first segment of tubing; a first outlet into a pressure dome; a second inlet from the pressure dome; and a second outlet configured for coupling with a second segment of tubing. The knob defines an expansion opening within a surface of the knob. The pressure dome is formed of a flexible elastomeric material and defines a fluid flow path between the first outlet and the second inlet. The pressure dome includes a vane configured to variably regulate flow through the fluid flow path in response to rotation of the knob. The pressure dome is configured to expand through the expansion opening in response to fluid pressure in the fluid flow path.

Abstract: An intravenous infusion tubing fitment comprises a body, a rotatable knob coupled with the body, and a pressure dome seated within the knob. The body defines; a first inlet configured for coupling with a first segment of tubing; a first outlet into a pressure dome; a second inlet from said pressure dome; and a second outlet configured for coupling with a said second segment of tubing. The knob defines an expansion opening within a surface of the. The pressure dome is formed of a flexible elastomeric material and defines a fluid flow path between the first outlet and the second inlet. The pressure dome includes a vane configured to variably regulate flow through the fluid flow path in response to rotation of the knob. The pressure dome is configured to expand through the expansion opening in response to fluid pressure in the fluid flow path.

Abstract: A pumping mechanism is disclosed that includes a plurality of peristaltic pumping actuators configured to selectively and sequentially compress adjacent portions of a first portion of an at least partially compressible pumping element having an inlet that is upstream of an outlet. The plurality of pumping actuators are further configured to reciprocate at a common drive frequency with a first phase offset between each adjacent pair of pumping actuators. The pumping mechanism also includes at least one compensation actuator arranged to selectively compress a second portion of the at least partially compressible pumping element that is disposed between the first portion and the outlet. The at least one compensation actuator is configured to reciprocate at an optimal displacement and at a modulation frequency that is an integer multiple of the fundamental drive frequency and with a second phase offset between the at least one compensation actuator and the adjacent pumping actuator.

Abstract: An intravenous infusion tubing fitment comprises a body, a rotatable knob coupled with the body, and a pressure dome seated within the knob. The body defines; a first inlet configured for coupling with a first segment of tubing; a first outlet into a pressure dome; a second inlet from said pressure dome; and a second outlet configured for coupling with a said second segment of tubing. The knob defines an expansion opening within a surface of the. The pressure dome is formed of a flexible elastomeric material and defines a fluid flow path between the first outlet and the second inlet. The pressure dome includes a vane configured to variably regulate flow through the fluid flow path in response to rotation of the knob. The pressure dome is configured to expand through the expansion opening in response to fluid pressure in the fluid flow path.