Abstract: A packaged intermittent urinary catheter comprising a single use catheter, a packaging surrounding the catheter, and a fluid reservoir holding a lubricant which, upon rupturing the fluid reservoir, is transferred into the packaging to immerse at least a portion of the catheter in the lubricant to prepare the catheter for use, wherein the lubricant comprises an antimicrobial medium. The invention further provides a method of using a packaged intermittent urinary catheter, and the use of a medium comprising at least one species independently chosen from: hypochlorous acid, at least one hypochlorite salt, chlorine dioxide, at least one chlorhexidine salt, and combinations thereof, as an antimicrobial medium for a single use intermittent urinary catheter.

Abstract: A computer-implemented system controls peripheral devices using artificial intelligence. Audio or video data captured by one or more microphones or cameras is processed to determine a participant's desire or related contextual information. Based on the determination, one or more peripheral devices are caused to act, such as by presenting related content or control outputs. The system may further note user sentiment regarding the actions taken and update a deep reinforcement learning model, enabling inference of subsequent desires. Sentiment may be derived from the processed audio or video data. In some embodiments, the system presents accompanying or supplemental context, optionally displayed via different portions of a user interface, to improve user interaction and understanding.

Abstract: Systems and methods are disclosed for analyzing video data from one or more cameras to determine object association and room readiness within an environment. The system detects at least one person and at least one object, correlates the object to an identified person, and determines that the person has exited while the object remains. Based on the determination, one or more control actions are automatically initiated, such as sending a notification, updating a scheduling application, or presenting a visual alert. In another embodiment, video data is processed to detect readiness factors including, e.g., chair count, cleanliness, or whiteboard markings. A readiness score is compared to a stored threshold to determine whether the environment is ready for use, and control actions are initiated accordingly, including, e.g., reassigning meetings or adjusting building management settings.

Abstract: An intelligent audiovisual control system is provided that utilizes a hierarchical, agentic artificial-intelligence framework. A large language model (LLM) operating as a room agent interprets input data and delegates execution to one or more task-specific LLMs that perform specialized functions. The system establishes communication among agents and includes an environment-assignment module for binding agents to physical environments or functional domains, and defines supervisory and subordinate relationships across physical environments. Each agent monitors sensor data and actuates connected control systems such as lighting, HVAC, and audiovisual equipment. The architecture enables scalable, context-aware, and privacy-preserving coordination of intelligent environments through distributed reasoning and autonomous task delegation.

Abstract: The present invention provides a system and a method for editing of an endogenous gene by replacing a gene portion sequence thereof comprised in a single exon with a transgene sequence, the system comprising at least one genome editing reagent designed for generating a double strand break (DSB) in a region spanning the gene portion sequence; and a replacement nucleic acid molecule comprising a coding sequence replacement (CDSR) construct designed for serving as a template for homology-directed repair (HDR) triggered by the DSB.

Abstract: The invention provides a reusable urinary catheter kit comprising a container comprising: a urinary catheter; and a medium comprising at least one species independently chosen from: hypochlorous acid, at least one hypochlorite salt, chlorine dioxide, and combinations thereof. The invention further provides a method of sterilising and/or lubricating a reusable urinary catheter using at least one species independently chosen from: hypochlorous acid, at least one hypochlorite salt, chlorine dioxide, and combinations thereof.

Abstract: A conferencing system may connect a processing unit to a camera and a microphone in a meeting room. A calibration module of the processing unit may generate a calibration strategy prior to obtaining video data from the camera, with the processing unit, in accordance with the calibration strategy. The processing unit may then translate the video data into spatial data that is utilized by a mapping module of the processing unit to identify a physical location of the microphone in the meeting room. The calibration module may determine a field of view operating parameter of the camera in response to the spatial data.

Abstract: A catheter storage and sterilisation device that has a housing and a removeable cartridge, the cartridge including a catheter-receiving chamber for receiving a catheter. The cartridge being removably attachable to the housing and having an opening in fluid communication with the housing. The housing has a chamber for receiving a sterilisation fluid and a mechanism for supplying a sterilisation fluid to the cartridge via the opening.

Abstract: A catheter storage and sterilisation device (99); the device comprising a catheter-receiving chamber (10) for receiving a catheter (1); a sterilisation fluid storage means (70) for storing a sterilisation fluid and an atomiser (53) or vaporiser configured to atomise or vaporise the sterilisation fluid to form an atomised or vaporised sterilisation fluid and to supply the atomised or vaporised sterilisation fluid to the catheter-receiving chamber (10).

Abstract: An intermittent catheter assembly that has a catheter having a proximal end for insertion into the body and a distal end; and a fluid collection bag arranged to receive fluid from the distal end of the catheter, wherein the fluid collection bag comprises a hand strap. The hand strap may comprise two ends, each end being attached to the fluid collection bag at substantially the same position on the fluid collection bag.

Abstract: The present invention is a modular exercise system made up of two handles, a segmented track, and two or more sliding carriages. The invention allows a user to safely and incrementally practice front and side split exercises by providing specific and adjustable stability and support. The invention can be extended to accommodate taller users and can also be fully disassembled and packed into a compact travelling configuration.

Abstract: The invention relates to intermittent catheters comprising a calixarene bonded to a surface thereof, in particular to provide a bacteria-repellent and/or lubricous coating on the outer surface of an intermittent catheter. The calixarene moiety may comprises hydrophilic surface groups to provide lubricity, whilst also providing a bacteria-repellent effect, especially useful preventing discomfort and/or infection for a user inserting multiple catheters per day.

Abstract: A door assembly for an appliance includes a frame door defining a vertical direction, a lateral direction, and a transverse direction, the frame door being attached to the cabinet and movable between an open position and a closed position to permit selective access to the cavity; an outer door slidably connected to the frame door, the outer door being slidable relative to the frame door between an open position and a closed position; and a slide assembly connecting the outer door to the frame door.

Abstract: A door assembly for an appliance includes a frame door defining a vertical direction, a lateral direction, and a transverse direction, the frame door being attached to the cabinet and movable between an open position and a closed position to permit selective access to the cavity; an outer door slidably connected to the frame door, the outer door being slidable relative to the frame door between an open position and a closed position; and a slide assembly connecting the outer door to the frame door.

Abstract: The present invention is a modular exercise system made up of two handles, a segmented track, and two or more sliding carriages. The invention allows a user to safely and incrementally practice front and side split exercises by providing specific and adjustable stability and support. The invention can be extended to accommodate taller users and can also be fully disassembled and packed into a compact travelling configuration.