Patents by Inventor Daniel C. Sigg
Daniel C. Sigg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20100292768Abstract: Electrical medical leads having active fixation electrodes, particularly helix electrodes intended to be screwed into body tissue, e.g., the heart, are disclosed having selectively applied insulation to optimize exposed electrode surface area and dispose the exposed electrode surface area toward tissue that is less traumatized by injury caused by screwing in the fixation helix. In a preferred fabrication method, an outer helical surface is masked by contact with a masking tube while a dielectric coating is applied to the inner helical surface of the coil turns of the helix, and the masking tube is removed when the dielectric coating has set. In one variation, at least one aperture is formed through the masking tube sidewall exposing an area of the outer helical surface thereby interrupting the uninsulated outer helical electrode.Type: ApplicationFiled: May 18, 2010Publication date: November 18, 2010Applicant: Medtronic, Inc.Inventors: John L. Sommer, Daniel C. Sigg, James A. Coles, JR.
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Publication number: 20100274221Abstract: A method for adjusting delivery of a therapeutic fluid to a patient suffering from or at risk of pulmonary arterial hypertension includes introducing the therapeutic fluid to a patient via a catheter at a predetermined rate. The catheter is positioned to deliver the fluid to the right ventricle or the pulmonary artery. The catheter a one-way valve configured to allow the fluid to flow from the catheter to the target location. The method further includes monitoring pressure of the target location by monitoring internal catheter pressure, and adjusting the rate at which the therapeutic fluid is introduced to the catheter based on the monitored pressure. The rate at which the fluid is introduced to the catheter is increased if internal catheter pressure increases, and the rate at which the fluid is introduced to the catheter is decreased if the internal catheter pressure decreases.Type: ApplicationFiled: April 26, 2010Publication date: October 28, 2010Applicant: Medtronic, Inc.Inventors: Daniel C. Sigg, Prasanga D. Hiniduma-Lokuge, Mary M. Morris
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Publication number: 20100234827Abstract: The present invention includes methods, systems, uses, and means for the delivery of one or more anti-fibrotic agents into the pericardial space for the treatment and prevention of heart failure (HF).Type: ApplicationFiled: March 11, 2010Publication date: September 16, 2010Inventors: Daniel C. Sigg, David Schwartzman, Eduardo N. Warman, Rodolphe Katra
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Patent number: 7778705Abstract: Heart pacing systems include at least one electronic or biological pacemaker as a primary pacemaker, and at least one electronic or biological pacemaker as a backup pacemaker. When implanted, the primary pacemaker(s) produce primary pacing stimuli that modulate cardiac function. The backup pacemaker(s) provide backup pacing stimuli when the electronic pacemaker is unable to modulate cardiac function at the predetermined pacing rate. The heart pacing systems are implemented by implantation in regions where they can provide pacing stimuli to cardiac tissue.Type: GrantFiled: October 31, 2006Date of Patent: August 17, 2010Assignee: Medtronic, Inc.Inventors: Daniel C. Sigg, Timothy G. Laske, Vinod Sharma, Orhan Soykan
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Patent number: 7742809Abstract: In general, the invention is directed to techniques for delivering macromolecules to a tissue site via electroporation. Particularly, a catheter detects contact between a distal end of the catheter and a target tissue site via a sensing electrode at the distal end of the catheter. The catheter delivers a fluid containing macromolecules to the tissue site upon detecting contact between the tissue site and the catheter. Concurrently or soon after delivery of the fluid, an electrical stimulus is applied to the tissue site. The electrical stimulus can be applied by the catheter or directly from a power supply, such as an implanted pulse generator. The electrical stimulus causes membranes of cells within the tissue site to destabilize, in turn, forming pores through which the macromolecules migrate into the cells of the tissue site.Type: GrantFiled: August 25, 2003Date of Patent: June 22, 2010Assignee: Medtronic, Inc.Inventors: Daniel C. Sigg, Daisy P. Cross, Jesus W. Casas-Bejar, Rodolfo A. Padua
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Patent number: 7720550Abstract: Electrical medical leads having active fixation electrodes, particularly helix electrodes intended to be screwed into body tissue, e.g., the heart, are disclosed having selectively applied insulation to optimize exposed electrode surface area and dispose the exposed electrode surface area toward tissue that is less traumatized by injury caused by screwing in the fixation helix. In a preferred fabrication method, an outer helical surface is masked by contact with a masking tube while a dielectric coating is applied to the inner helical surface of the coil turns of the helix, and the masking tube is removed when the dielectric coating has set. In one variation, at least one aperture is formed through the masking tube sidewall exposing an area of the outer helical surface thereby interrupting the uninsulated outer helical electrode.Type: GrantFiled: December 3, 2004Date of Patent: May 18, 2010Assignee: Medtronic, Inc.Inventors: John L Sommer, Daniel C Sigg, James A Coles, Jr.
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Publication number: 20100016740Abstract: A cardiac ischemic protection system and method for conditioning a patient's heart is provided. The method can include detecting acute myocardial infarction, angina pectoris, silent ischemia, or stunning and providing closed-loop dyssynchronous pacing to the patient's heart to precondition and/or postcondition the patient's heart in order to reduce ischemic damage.Type: ApplicationFiled: July 15, 2008Publication date: January 21, 2010Inventors: Daniel C. Sigg, James A. Coles, JR., Dwight H. Warkentin, Deborah Ann Jaye
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Publication number: 20090099611Abstract: A composition for implantation into cardiac tissue includes a biological pacemaker that, when implanted, expresses an effective amount of a mutated hyperpolarization-activated and cyclic nucleotide-gated (HCN) isoform to modify Ih when compared with wild-type HCN. Methods for implementing each of the biological pacemakers include implanting each of biological pacemakers into cardiac tissue.Type: ApplicationFiled: November 30, 2006Publication date: April 16, 2009Inventors: Daniel C. Sigg, Vinod Sharma, Yong-Fu Xiao
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Publication number: 20080228133Abstract: A sympatholytic cardiovascular agent delivered by a drug delivery pump to a central nervous system site to alleviate symptoms of acute or chronic cardiac insult or impaired cardiac performance. The drug delivery pump can be external or implantable infusion pump (IIP) coupled with a drug infusion catheter extending to the site. A patient activator can command delivery of a dosage and/or an implantable heart monitor (IHM) coupled with a sensor can detect physiologic parameters associated with cardiac insult or impaired cardiac performance and trigger dosage delivery. The IIP and IHM can be combined into a single implantable medical device (IMD) or can constitute separate IMDs that communicate by any of known communication mechanisms. The sympatholytic cardiovascular agent is one of the group consisting of an alpha-adrenergic agonist and an alpha2-adrenergic agonist (e.g.Type: ApplicationFiled: May 28, 2008Publication date: September 18, 2008Inventors: KEITH R. HILDEBRAND, Michael R. Ujhelyi, Xiaohong Zhou, Daniel C. Sigg, Linda M. Page
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Publication number: 20080172012Abstract: An injection needle comprises an elongated body having an outer surface and an inner surface defining a longitudinal channel through the tubular body. The elongated body further comprises a distal end and at least one lateral delivery port extending from the inner surface to the outer surface proximate the distal end and fluidly coupled to the longitudinal channel. A distal tip is coupled to the distal end and comprises a radio-opaque material.Type: ApplicationFiled: October 31, 2006Publication date: July 17, 2008Inventors: Prasanga D. Hiniduma-Lokuge, Daniel C. Sigg, John L. Sommer, Matthew D. Bonner, Brian C.A. Fernandes
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Patent number: 7390311Abstract: A sympatholytic cardiovascular agent delivered by a drug delivery pump to a central nervous system site to alleviate symptoms of acute or chronic cardiac insult or impaired cardiac performance. The drug delivery pump can be external or implantable infusion pump (IIP) coupled with a drug infusion catheter extending to the site. A patient activator can command delivery of a dosage and/or an implantable heart monitor (IHM) coupled with a sensor can detect physiologic parameters associated with cardiac insult or impaired cardiac performance and trigger dosage delivery. The IIP and IHM can be combined into a single implantable medical device (IMD) or can constitute separate IMDs that communicate by any of known communication mechanisms. The sympatholytic cardiovascular agent is one of the group consisting of an alpha-adrenergic agonist and an alpha2-adrenergic agonist (e.g.Type: GrantFiled: July 30, 2004Date of Patent: June 24, 2008Assignee: Medtronic, Inc.Inventors: Keith R. Hildebrand, Michael R. Ujhelyi, Xiaohong Zhou, Daniel C. Sigg, Linda M. Page
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Publication number: 20080103537Abstract: Heart pacing systems include at least one electronic or biological pacemaker as a primary pacemaker, and at least one electronic or biological pacemaker as a backup pacemaker. When implanted, the primary pacemaker(s) produce primary pacing stimuli that modulate cardiac function. The backup pacemaker(s) provide backup pacing stimuli when the electronic pacemaker is unable to modulate cardiac function at the predetermined pacing rate. The heart pacing systems are implemented by implantation in regions where they can provide pacing stimuli to cardiac tissue.Type: ApplicationFiled: October 31, 2006Publication date: May 1, 2008Inventors: Daniel C. Sigg, Timothy G. Laske, Vinod Sharma, Orhan Soykan
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Patent number: 7274966Abstract: A medical fluid delivery system includes an implantable medical lead including a fixation element adapted to secure the lead to a tissue site and a fluid delivery device including a tissue piercing distal tip; the device is adapted to pass through a proximal port, a lumen and a distal port of the lead. The system further includes means for adjusting a position of the device distal tip with respect to the lead distal port.Type: GrantFiled: January 8, 2004Date of Patent: September 25, 2007Assignee: Medtronic, Inc.Inventors: John L. Sommer, James A. Coles, Jr., Daniel C. Sigg
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Patent number: 7232435Abstract: A sympatholytic cardiovascular agent delivered by a drug delivery pump to a central nervous system site to alleviate symptoms and otherwise treat heart failure (HF) and pathologies associated with HF. The drug delivery pump can be external or implantable infusion pump (IIP) coupled with a drug infusion catheter extending to the site. A patient activator can command delivery of a dosage and/or an implantable heart monitor (IHM) coupled with a sensor can detect physiologic parameters associated with HF (or pathologies associated with HF) and trigger dosage delivery. The IIP and IHM can be combined into a single implantable medical device (IMD) or can constitute separate IMDs that communicate by any of known communication mechanisms. The sympatholytic cardiovascular agent is one of the group consisting of an alpha-adrenergic agonist and an alpha2-adrenergic agonist, e.g.Type: GrantFiled: February 6, 2004Date of Patent: June 19, 2007Assignee: Medtronic, Inc.Inventors: Keith R. Hildebrand, Michael R. Ujhelyi, Xiaohong Zhou, Daniel C. Sigg, Linda M. Page
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Patent number: 7187971Abstract: A medical fluid delivery system includes an implantable medical lead and a fluid delivery device; the device is adapted to pass through a proximal port, a lumen and a distal port of the lead. The fluid delivery device includes a tissue piercing distal tip and a pre-formed curve in proximity to the distal tip such that the tip is directed away from a lead fixation element after passing beyond the distal port of the lead.Type: GrantFiled: January 8, 2004Date of Patent: March 6, 2007Assignee: Medtronic, Inc.Inventors: John L. Sommer, James A. Coles, Jr., Daniel C. Sigg
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Patent number: 7103418Abstract: A medical system incorporating fluid delivery and lead delivery lumens dispense fluid into a volume of tissue. The fluid comprises or contains a pharmacologic, genetic, or biologic agent. The fluid may be dispensed initially during implantation or later using a minimally invasive medical procedure.Type: GrantFiled: October 2, 2002Date of Patent: September 5, 2006Assignee: Medtronic, Inc.Inventors: Timothy G. Laske, Daniel C. Sigg, John L. Sommer
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Patent number: 6931286Abstract: An implantable lead system includes an elongated device slideably engaged within a lumen of a lead body. A distal portion of the elongated device is slidable through a helix tip coupled to a distal end of the lead body by passing through a pierceable fluid-tight seal disposed in proximity to the distal end of the lead body; the seal prevents ingress of bodily fluid into the lumen of the lead body.Type: GrantFiled: April 25, 2003Date of Patent: August 16, 2005Assignee: Medtronic, Inc.Inventors: Daniel C. Sigg, John L. Sommer
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Publication number: 20040147963Abstract: A medical fluid delivery system includes an implantable medical lead including a fixation element adapted to secure the lead to a tissue site and a fluid delivery device including a tissue piercing distal tip; the device is adapted to pass through a proximal port, a lumen and a distal port of the lead. The system further includes means for adjusting a position of the device distal tip with respect to the lead distal port.Type: ApplicationFiled: January 8, 2004Publication date: July 29, 2004Applicant: Medtronic, Inc.Inventors: John L. Sommer, James A. Coles, Daniel C. Sigg
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Publication number: 20040143314Abstract: A medical fluid delivery system includes an implantable medical lead and a fluid delivery device; the device is adapted to pass through a proximal port, a lumen and a distal port of the lead. The fluid delivery device includes a tissue piercing distal tip and a pre-formed curve in proximity to the distal tip such that the tip is directed away from a lead fixation element after passing beyond the distal port of the lead.Type: ApplicationFiled: January 8, 2004Publication date: July 22, 2004Applicant: Medtronic, Inc.Inventors: John L. Sommer, James A. Coles, Daniel C. Sigg
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Publication number: 20040068312Abstract: An implantable lead system includes an elongated device slideably engaged within a lumen of a lead body. A distal portion of the elongated device is slidable through a helix tip coupled to a distal end of the lead body by passing through a pierceable fluid-tight seal disposed in proximity to the distal end of the lead body; the seal prevents ingress of bodily fluid into the lumen of the lead body.Type: ApplicationFiled: April 25, 2003Publication date: April 8, 2004Applicant: Medtronic, Inc.Inventors: Daniel C. Sigg, John L. Sommer