Patents by Inventor Daniel-Henri Caignard

Daniel-Henri Caignard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Indole compounds, a process for their preparation and pharmaceutical compositions containing them
    Patent number: 8003682
    Abstract: Compounds of formula (I): wherein: R1 represents an alkyl, cycloalkyl or cycloalkylalkyl group, R2 represents a linear or branched (C1-C6)alkyl group, and n represents from 1 to 6. Medicaments.
    Type: Grant
    Filed: October 17, 2007
    Date of Patent: August 23, 2011
    Assignee: Les Laboratories Servier
    Inventors: Pascal Marchand, Vincent Babonneau, Sylvie Piessard, Muriel Duflos, Jean Albert Boutin, Valérie Audinot, Philippe Delagrange, Daniel-Henri Caignard
  • Naphthalene compounds, a process for their preparation and pharmaceutical compositions containing them
    Patent number: 7947852
    Abstract: Compounds of formula (I): wherein: R1 represents alkyl, alkenyl, haloalkyl, polyhaloalkyl, cycloalkyl, cycloalkylalkyl, aryl, arylalkyl, heteroaryl or heteroarylalkyl, X represents a group N—OR2 wherein R2 represents a hydrogen atom or an alkyl group. Medicinal products containing the same which are useful in treating disorders of the melatoninergic system.
    Type: Grant
    Filed: July 1, 2008
    Date of Patent: May 24, 2011
    Assignee: Les Laboratoires Servier
    Inventors: Said Yous, Mohamed Ettaoussi, Ahmed Sabaouni, Pascal Berthelot, Michael Spedding, Philippe Delagrange, Daniel-Henri Caignard, Mark Millan
  • Piperidine compounds, a process for their preparation and pharmaceutical compositions containing them
    Publication number: 20110021569
    Abstract: Compounds of formula (I): wherein: R1 represents a hydrogen atom or a methyl group, R2 represents a bromine atom, a fluorine atom or a trifluoromethyl group. Medicinal products containing the same which are useful in treating cognitive disorders associated with pathologies of the central nervous system.
    Type: Application
    Filed: July 20, 2010
    Publication date: January 27, 2011
    Applicants: LES LABORATOIRES SERVIER, UNIVERSITE, UNIVERSITE DE NANTES
    Inventors: Iuliana Botez, Jacques Lebreton, Pierre Lestage, Caroline Louis, Monique Mathe, Daniel-Henri Caignard
  • INDOLE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
    Publication number: 20100204276
    Abstract: Compounds of formula (I): wherein: R1 represents an alkyl, cycloalkyl or cycloalkylalkyl group, R2 and R3, together with the nitrogen atom carrying them, form a heterocycle having from 5 to 8 ring members, and n represents from 2 to 6. Medicinal products containing the same which are useful in treating disorders of the to melatoninergic system.
    Type: Application
    Filed: October 17, 2007
    Publication date: August 12, 2010
    Applicant: LES LABORATOIRES SERVIER
    Inventors: Pascal Marchand, Vincent Babonneau, Sylvie Piessard, Muriel Duflos, Jean Albert Boutin, Valerie Audinot, Philippe Delagrange, Daniel-Henri Caignard
  • NAPHTHALENE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
    Publication number: 20100168244
    Abstract: Compounds of formula (I): wherein: R1 represents alkyl, alkenyl, haloalkyl, polyhaloalkyl, cycloalkyl, cycloalkylalkyl, aryl, arylalkyl, heteroaryl or heteroarylalkyl, X represents a group N—OR2 wherein R2 represents a hydrogen atom or an alkyl group. Medicinal products containing the same which are useful in treating disorders of the melatoninergic system.
    Type: Application
    Filed: July 1, 2008
    Publication date: July 1, 2010
    Applicant: LESS LABORATOIRES SERVIER
    Inventors: Said Yous, Mohamed Ettaoussi, Ahmed Sabaouni, Pascal Berthelot, Michael Spedding, Philippe Delagrange, Daniel-Henri Caignard, Mark Millan
  • Cycloalkylated benzothiadiazines, a process for their preparation and pharmaceutical compositions containing them
    Patent number: 7741320
    Abstract: Compounds of formula (I): wherein: RCy represents an unsubstituted or substituted cycloalkyl group or cycloalkylalkyl group, R1, R2, R3 and R4, which may be the same or different, each represent a hydrogen or halogen atom or a nitro group; a cyano group; a hydroxy group; an alkoxy group; an alkyl group; an unsubstituted or substituted amino group; a carboxy group; an alkoxycarbonyl group; an aryloxycarbonyl group; an unsubstituted or substituted aminocarbonyl group. Medicinal products containing the same which are useful in treating or preventing conditions treatable by an AMPA receptor modulator.
    Type: Grant
    Filed: July 9, 2009
    Date of Patent: June 22, 2010
    Assignee: Les Laboratoires Servier
    Inventors: Pierre Francotte, Pascal De Tullio, Bernard Pirotte, Laurence Danober, Pierre Lestage, Daniel-Henri Caignard
  • NAPHTHALENE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
    Publication number: 20100137446
    Abstract: Compounds of formula (I): wherein: R1 represents alkyl, alkenyl, haloalkyl, polyhaloalkyl, cycloalkyl, cycloalkylalkyl, aryl, arylalkyl, heteroaryl or heteroarylalkyl, R2 represents a fluorine atom or an alkyl group substituted by one or more fluorine atoms. Medicinal products containing the same which are useful in treating disorders of the melatoninergic system.
    Type: Application
    Filed: July 1, 2008
    Publication date: June 3, 2010
    Inventors: Said Yous, Mohamed Ettaoussi, Ahmed Sabaouni, Pascal Berthelot, Michael Spedding, Philippe Delagrange, Daniel-Henri Caignard, Mark Millan
  • Indole compounds, a process for their preparation and pharmaceutical compositions containing them.
    Publication number: 20100063128
    Abstract: Compounds of formula (I): wherein: R1 represents an alkyl, cycloalkyl or cycloalkylalkyl group, R2 represents a linear or branched (C1-C6)alkyl group, and n represents from 1 to 6.
    Type: Application
    Filed: October 17, 2007
    Publication date: March 11, 2010
    Inventors: Pascal Marchand, Vincent Babonneau, Sylvie Piessard, Muriel Duflos, Jean Albert, Valerie Audinot, Philippe Delagrange, Daniel-Henri Caignard
  • Cycloalkylated benzothiadiazines, a process for their preparation and pharmaceutical compostions containing them
    Publication number: 20100009974
    Abstract: Compounds of formula (I): wherein: RCy represents an unsubstituted or substituted cycloalkyl group or cycloalkylalkyl group, R1, R2, R3 and R4, which may be the same or different, each represent a hydrogen or halogen atom or a nitro group; a cyano group; a hydroxy group; an alkoxy group; an alkyl group; an unsubstituted or substituted amino group; a carboxy group; an alkoxycarbonyl group; an aryloxycarbonyl group; an unsubstituted or substituted aminocarbonyl group. Medicinal products containing the same which are useful in treating or preventing conditions treatable by an AMPA receptor modulator.
    Type: Application
    Filed: July 9, 2009
    Publication date: January 14, 2010
    Applicant: LES LABORATOIRES SERVIER
    Inventors: Pierre FRANCOTTE, Pascal De Tullio, Bernard Pirotte, Laurence Danober, Pierre Lestage, Daniel-Henri Caignard
  • Heterocyclic Oxime Compounds, Process for Their Preparation and Pharmaceutical Compositions Containing Them
    Publication number: 20090274674
    Abstract: Compounds of formula (I): wherein: X represents a hydrogen or halogen atom or an alkyl group, R1, R2, R3 and R4 are as defined in the description, A represents an alkylene chain as defined in the description, B represents an alkyl or alkenyl group substituted by a group D represents a pyridine nucleus.
    Type: Application
    Filed: December 19, 2006
    Publication date: November 5, 2009
    Applicant: LES LABORATOIRES SERVIER
    Inventors: Franck Suzenet, Gerald Guillaumet, Christelle Pillard, Carine Bassene, Catherine Dacquet, Alain Ktorza, Daniel-Henri Caignard
  • Heterocyclic Cycloalkyl Compounds, a Process for their Preparation and Pharmaceutical Compositions Containing Them
    Publication number: 20090239917
    Abstract: Compounds of formula (I): wherein: R1 represents a (C3-C8)cycloalkyl group, R2 represents a group of formula (II) as defined in the description, X represents an oxygen atom or an N—OR? group wherein R? represents a hydrogen atom, a linear or branched (C1-C6)alkyl group, an aryl group or an aryl-(C1-C6)alkyl group in which the alkyl moiety may be linear or branched. Medicinal products containing the same which are useful as hypoglycaemic and hypolipaemic agents.
    Type: Application
    Filed: March 5, 2007
    Publication date: September 24, 2009
    Applicant: Les Laboratoires Servier
    Inventors: Aurelie Hurtevent, Jean-Martial L'Helgoual'ch, Pascal Carato, Nicolas Lebegue, Veronique Leclerc, Morgan Le Naour, Pascal Berthelot, Catherine Dacquet, Alain Ktorza, Daniel-Henri Caignard
  • Heterocyclic Oxime Compounds a Process for Their Preparation and Pharmaceutical Compositions Containing Them
    Publication number: 20090124656
    Abstract: Compounds of formula (I): wherein: R1, R2, R3, R4 and X are as defined in the description, A represents an alkylene chain as defined in the description, B represents an alkyl or alkenyl group substituted by a group or R7, or B represents a group or R7. Medicinal products containing the same which are useful as hypoglycaemic and hypolipaemic agents.
    Type: Application
    Filed: January 26, 2006
    Publication date: May 14, 2009
    Applicant: LES LABORATOIRES SERVIER
    Inventors: Cicile Parmenon, Marie-Claude Viaud-Massuard, Jerome Guillard, Catherine Dacuet, Alain Ktorza, Daniel- Henri Caignard
  • Thiadiazine derivatives and use thereof as positive AMPA receptor modulators
    Patent number: 7476668
    Abstract: Compounds of formula (I): wherein: A represents thienyl, furyl, pyrrolyl, oxathiol, thiazole, isothiazole, oxazole or imidazole, represents a single bond or a double bond, R1 represents hydrogen, linear or branched (C1-C6)alkyl optionally substituted by one or more groups selected from halogen or (C1-C6)alkoxy-(C1-C6)alkyl, R2 represents hydrogen or linear or branched (C1-C6)alkyl group optionally substituted by one or more halogen, R3 represents hydrogen or a group selected from linear or branched (C1-C6)alkyl, CONHR? and SO2NHR? wherein R? represents linear or branched (C1-C6)alkyl, its enantiomers and diastereoisomers, and addition salts thereof with a pharmaceutically acceptable acid or base. Medicinal products containing the same, which are useful as AMPA inhibitors.
    Type: Grant
    Filed: May 4, 2004
    Date of Patent: January 13, 2009
    Assignee: Les Laboratoires Servier
    Inventors: Emmanuel Graindorge, Pierre Francotte, Stéphane Boverie, Pascal De Tullio, Bernard Pirotte, Pierre Lestage, Laurence Danober, Pierre Renard, Daniel-Henri Caignard
  • Naphthalene compounds
    Patent number: 7462741
    Abstract: A compound selected from those of formula (I): Medicinal products containing the same which are useful in the treatment of disorders of the melatoninergic system.
    Type: Grant
    Filed: June 28, 2007
    Date of Patent: December 9, 2008
    Assignee: Les Laboratoires Servier
    Inventors: Said Yous, Basile Peres, Ahmed Sabaouni, Pascal Berthelot, Michael Spedding, Philippe Delagrange, Daniel-Henri Caignard, Mark Millan
  • Naphthalene compounds
    Patent number: 7435850
    Abstract: A compound selected from those of formula (I): Medicinal products containing the same which are useful in the treatment of disorders of the melatoninergic system.
    Type: Grant
    Filed: June 29, 2007
    Date of Patent: October 14, 2008
    Assignee: Les Laboratoires Servier
    Inventors: Said Yous, Basile Peres, Ahmed Sabaouni, Pascal Berthelot, Michael Spedding, Philippe Delagrange, Daniel-Henri Caignard, Mark Millan
  • Heterocyclic Oxime Compounds, A Process For Their Preparation And Pharmaceutical Compositions Containing Them.
    Publication number: 20080113974
    Abstract: Compounds of formula (I): wherein: X represents an oxygen atom or a sulphur atom, R1, R2, R3 and R4 are as defined in the description, A represents an alkylene chain as defined in the description, and B represents an alkyl or alkenyl group substituted by a group or R7, or B represents a group or R7.
    Type: Application
    Filed: January 26, 2006
    Publication date: May 15, 2008
    Applicant: LES LABORATOIRES SERVIER
    Inventors: Aurelie Hurtevent, Jean-Martial L' Helgoual' Ch, Pascal Carato, Nicolas Lebegue, Veronique Leclerc, Pascal Berthelot, Catherine Dacquet, Alain Ktorza, Daniel-Henri Caignard
  • Pyridopyrimidinone compounds, method for production thereof and medicaments comprising the same
    Patent number: 7361662
    Abstract: A compound of formula (I): wherein: R1, R2, R3, R4 are defined in the description, its enantiomers, diastereoisomers, tautomers and also addition salts thereof with a pharmaceutically acceptable acid or base, and medicinal products containing the same which are useful as kinase modulators.
    Type: Grant
    Filed: November 4, 2003
    Date of Patent: April 22, 2008
    Assignee: Les Laboratoires Servier
    Inventors: Sylvain Rault, Jean-Charles Lancelot, Marina Kopp, Daniel-Henri Caignard, Bruno Pfeiffer, Pierre Renard
  • Naphthalene compounds
    Publication number: 20080004349
    Abstract: A compound selected from those of formula (I): Medicinal products containing the same which are useful in the treatment of disorders of the melatoninergic system.
    Type: Application
    Filed: June 28, 2007
    Publication date: January 3, 2008
    Applicant: LES LABORATOIRES SERVIER
    Inventors: Said Yous, Basile Peres, Ahmed Sabaouni, Pascal Berthelot, Michael Spedding, Philippe Delagrange, Daniel-Henri Caignard, Mark Millan
  • Naphthalene compounds
    Publication number: 20080004348
    Abstract: A compound selected from those of formula (I): wherein: R1 represents a group R4 or NHR4, wherein R4 is as defined in the description; R2 represents a substituted linear or branched (C1-C6)alkyl group; R3 represents a hydrogen or halogen atom or a linear or branched (C1-C6)alkyl or linear or branched (C2-C6)alkenyl group. Medicinal products containing the same which are useful in the treatment of disorders of the melatoninergic system.
    Type: Application
    Filed: June 27, 2007
    Publication date: January 3, 2008
    Applicant: LES LABORATOIRES SERVIER
    Inventors: Said Yous, Basile Peres, Ahmed Sabaouni, Pascal Berthelot, Michael Spedding, Philippe Delagrange, Daniel-Henri Caignard, Matthieu Desroses, Jean-Albert Boutin, Valerie Audinot
  • Naphthalene compounds
    Publication number: 20080004350
    Abstract: A compound selected from those of formula (I): Medicinal products containing the same which are useful in the treatment of disorders of the melatoninergic system.
    Type: Application
    Filed: June 29, 2007
    Publication date: January 3, 2008
    Applicant: LES LABORATOIRES SERVIER
    Inventors: Said Yous, Basile Peres, Ahmed Sabaouni, Pascal Berthelot, Michael Spedding, Philippe Delagrange, Daniel-Henri Caignard, Mark Millan