Patents by Inventor Daniel-Henri Caignard

Daniel-Henri Caignard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5843947
    Abstract: A compound selected from those of formula (I): ##STR1## where m is equal to 0 or 1 and Het, A, X, R,R.sub.1, R.sub.2, R.sub.3, R.sub.4 and the ring ##STR2## are defined in the description, and a medicinal product comprising the same for treating an inflammatory disorder.
    Type: Grant
    Filed: March 26, 1997
    Date of Patent: December 1, 1998
    Assignee: Adir et Compagnie
    Inventors: Jean-Michel Robert, Odile Rideau, Sylvie Robert-Piessard, Jacqueline Courant, Guillaume Le Baut, Daniel-Henri Caignard, Pierre Renard, Gerard Adam
  • Patent number: 5807882
    Abstract: A compound of formula (I): ##STR1## in which R.sup.1, R.sup.2, X and Y are as defined in the description, the isomers thereof and the addition salts thereof with a pharmaceutically acceptable acid or base, and medicinal products containing the same are useful in the treatment of certain cancers.
    Type: Grant
    Filed: November 7, 1997
    Date of Patent: September 15, 1998
    Assignee: Adir et Compagnie
    Inventors: Gerard Coudert, Siham Khatib, Pascale Moreau, Daniel-Henri Caignard, Pierre Renard, Ghanem Atassi, Alain Pierre
  • Patent number: 5767128
    Abstract: The invention relates to a compound selected from those of formula (I): ##STR1## wherein R.sub.1, W and Y are as defined in the description, its geometric and/or optical isomers, and its pharmaceutically-acceptable addition salts with an acid or a base useful as analgesies.
    Type: Grant
    Filed: November 5, 1996
    Date of Patent: June 16, 1998
    Assignee: Adir et Compagnie
    Inventors: Gerald Guillaumet, Marie-Claude Viaud, Laurence Savelon, Panayota Pavli, Pierre Renard, Bruno Pfeiffer, Daniel-Henri Caignard, Jean-Guy Bizot-Espiard, Gerard Adam
  • Patent number: 5712294
    Abstract: A compound selected from those of formula (I): ##STR1## where m is equal to 0 or 1andHet, A, X, R, R.sub.1, R.sub.2, R.sub.3, R.sub.4 and the ring ##STR2## are defined in the description, and a medicinal product comprising the same for treating an inflammatory disorder.
    Type: Grant
    Filed: May 25, 1995
    Date of Patent: January 27, 1998
    Assignee: Adir Et Compagnie
    Inventors: Jean-Michel Robert, Odile Rideau, Sylvie Robert-Piessard, Jacqueline Courant, Guillaume Le Baut, Daniel-Henri Caignard, Pierre Renard, Gerard Adam
  • Patent number: 5703118
    Abstract: A method of treating a mammal afflicted with a disorder associated with the Na.sup.+ -independent Cl.sup.- /HCO.sub.3 - exchanger comprising the step of administering a compound selected from those of formula (I): ##STR1## in which R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7, R.sub.8, R.sub.9, R.sub.10, R.sub.11 and n are as defined in the description, which is effective for alleviating the said disorder.
    Type: Grant
    Filed: May 3, 1996
    Date of Patent: December 30, 1997
    Assignee: Adir et Compagnie
    Inventors: Ludovic Durand, Jean-Paul Babingui, Claudie Moulin, Sylvie Robert-Piessard, Guillaume Le Baut, Elisabeth Scalbert, Daniel-Henri Caignard, Pierre Renard
  • Patent number: 5691340
    Abstract: A compound selected from those of formula (I): ##STR1## where RA, RB, RC, RD, A, n, X, Y and Ar are defined in the description, and a medicinal product comprising the same for treating a mammal afflicted with a disease associated with sigma receptors.
    Type: Grant
    Filed: September 14, 1995
    Date of Patent: November 25, 1997
    Assignee: Adir et Compagnie
    Inventors: Genevieve Baziard-Mouysset, Sallouma Younes, Youssef Labssita, Marc Payard, Daniel-Henri Caignard, Pierre Renard, Marie-Claire Rettori
  • Patent number: 5688811
    Abstract: The invention relates to a compound selected from those of formula (I): ##STR1## in which R.sub.1, R.sub.2, R.sub.3, X and n are as defined in the description, the optical isomers thereof, and the addition salts thereof with a pharmaceutically acceptable acid or baseand medicinal product containing the same, useful for treating a mammal afflicted with a pathology associated with the sigma receptors.
    Type: Grant
    Filed: December 8, 1995
    Date of Patent: November 18, 1997
    Assignee: Adir et Compagnie
    Inventors: Ange Mouithys-Mickalad, Patrick Depreux, Daniel Lesieur, Gerard Adam, Daniel-Henri Caignard, Pierre Renard, Marie-Claire Rettori
  • Patent number: 5688820
    Abstract: The invention relates to a compound selected from those of formula (I): ##STR1## in which R.sub.1, R.sub.2, R.sub.3, X and n are as defined in the description, the optical isomers thereof, and the addition salts thereof with a pharmaceutically acceptable acid or base and medicinal product containing the same, useful for treating a mammal afflicted with a pathology associated with the sigma receptors.
    Type: Grant
    Filed: December 8, 1995
    Date of Patent: November 18, 1997
    Assignee: Adir et Compagnie
    Inventors: Ange Mouithys-Mickalad, Patrick Depreux, Daniel Lesieur, Gerard Adam, Daniel-Henri Caignard, Pierre Renard, Marie-Claire Rettori
  • Patent number: 5668138
    Abstract: A compound selected from those of formula (I): ##STR1## where RA, RB, RC, RD, A, n, X, Y and Ar are defined in the description, and a medicinal product comprising the same for treating a mammal afflicted with a disease associated with sigma receptors.
    Type: Grant
    Filed: July 10, 1996
    Date of Patent: September 16, 1997
    Assignee: Adir Et Compagnie
    Inventors: Genevieve Baziard-Mouysset, Sallouma Younes, Youssef Labssita, Marc Payard, Daniel-Henri Caignard, Pierre Renard, Marie-Claire Rettori
  • Patent number: 5618819
    Abstract: The invention relates to a compound selected from those of formula (I): ##STR1## wherein R.sub.1, W and Y are as defined in the description, its geometric and/or optical useful as anti-algies.
    Type: Grant
    Filed: July 3, 1995
    Date of Patent: April 8, 1997
    Assignee: Adir et Compagnie
    Inventors: G erald Guillaumet, Marie-Claude Viaud, Laurence Savelon, Panayota Pavli, Pierre Renard, Bruno Pfeiffer, Daniel-Henri Caignard, Jean-Guy Bizot-Espiard, G erard Adam
  • Patent number: 5585390
    Abstract: Compounds of the general formula: ##STR1## wherein m, X, Y, A, R.sub.2 and R.sub.3 are defined in the description, and medicaments containing the same.
    Type: Grant
    Filed: May 9, 1995
    Date of Patent: December 17, 1996
    Assignee: Adir Et Compagnie
    Inventors: Muriel Duflos, Sylvie Robert-Piessard, Lucien Welin, Guillaume Le Baut, Daniel-Henri Caignard, Pierre Renard, G erard Adam
  • Patent number: 5569669
    Abstract: The invention relates to a compound selected from those of formula (I): ##STR1## in which R.sub.1, R.sub.2, R.sub.2', R.sub.2", R.sub.2'", R.sub.3 and n are as defined in the description, an optical isomer, and an addition salt thereof with a pharmaceutically-acceptable acid or base,and medicinal product containing the same useful for treating a mammal afflicted with a disorder associated to 5-HT.sub.1A or 5-HT.sub.2C receptors.
    Type: Grant
    Filed: March 10, 1995
    Date of Patent: October 29, 1996
    Assignee: Adir et Compagnie
    Inventors: G erald Guillaumet, Marie-Claude Viaud, Pierre Renard, G erard Adam, Daniel-Henri Caignard, B eatrice Guardiola-Lemaitre, Marie-Claire Rettori
  • Patent number: 5534511
    Abstract: The invention relates to a compound selected from those of formula (I): ##STR1## in which R.sub.1, R.sub.2, R.sub.3, X and n are as defined in the description, the optical isomers thereof, and the addition salts thereof with a pharmaceutically acceptable acid or base and medicinal product containing the same, useful for treating a mammal afflicted with a pathology associated with the sigma receptors.
    Type: Grant
    Filed: March 21, 1995
    Date of Patent: July 9, 1996
    Assignee: Adir et Compagnie
    Inventors: Ange Mouithys-Mickalad, Patrick Depreux, Daniel Lesieur, Gerard Adam, Daniel-Henri Caignard, Pierre Renard, Marie-Claire Rettori
  • Patent number: 5534517
    Abstract: The invention relates to a compound selected from those of formula (I): ##STR1## wherein Ar, n, B and A are as defined in the description, to their optical isomers, and to their addition salts there of with a pharmaceutically-acceptable acid or base. The compounds are useful for treating or preventing anxiety and depression.
    Type: Grant
    Filed: August 26, 1994
    Date of Patent: July 9, 1996
    Assignee: Adir Et Compagnie
    Inventors: Ousmane Diouf, Daniel Lesieur, Patrick Depreux, Beatrice Guardiola-Lemaitre, Daniel-Henri Caignard, Pierre Renard, Gerard Adam
  • Patent number: 5519023
    Abstract: The invention relates to compounds of the general formula (I): ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6 and Z are as defined in the description, their optical isomers and their addition salts with a pharmaceutically-acceptable acid or base and medicaments containing the same, useful in the treatment and prevention of stress, anxiety, and related ailments.
    Type: Grant
    Filed: July 2, 1993
    Date of Patent: May 21, 1996
    Assignee: Adir et Compagnie
    Inventors: Marc Payard, Genevieve Baziard-Mouysset, Gilbert De Saqui-Sannes, Beatrice Guardiola, Daniel-Henri Caignard, Pierre Renard, Gerard Adam
  • Patent number: 5512569
    Abstract: The invention relates to the compounds of formula (I): ##STR1## in which R.sub.1 and R.sup.2 are as defined in the description, the optical isomers thereof,and an addition salt thereof with a pharmaceutically-acceptable acid or base, and medicinal product useful for treating a mammal afflicted with a disease associated with sigma receptors.
    Type: Grant
    Filed: March 21, 1995
    Date of Patent: April 30, 1996
    Assignee: Adir et Compagnie
    Inventors: Hamid A. Mansour, Thierry Taverne, Raymond Houssin, Isabelle Lesieur, Patrick Depreux, Geard Adam, Daniel-Henri Caignard, Pierre Renard, Marie-Claire Rettori
  • Patent number: 5470864
    Abstract: Compounds of the general formula: ##STR1## wherein m, X, Y, A, R.sub.2 and R.sub.3 are defined in the description.
    Type: Grant
    Filed: June 30, 1994
    Date of Patent: November 28, 1995
    Assignee: Adir et Compagnie
    Inventors: Muriel Duflos, Sylvie Robert-Piessard, Lucien Welin, Guillaume Le Baut, Daniel-Henri Caignard, Pierre Renard, Gerard Adam
  • Patent number: 5395834
    Abstract: A compound selected from those of formula (I): ##STR1## in which R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7, R.sub.8, R.sub.9 and n are as defined in the description, its optical isomers, and its addition salts thereof with a pharmaceutically-acceptable acid or base, and medicinal product containing the same for treating a mammal afflicted with a disorder connected with peroxydation processes and biosynthesis of eicosanoids.
    Type: Grant
    Filed: April 11, 1994
    Date of Patent: March 7, 1995
    Assignee: Adir et Compagnie
    Inventors: Guillaume Le Baut, Jean-Paul Babingui, Sylvie Robert-Piessard, Pierre Renard, Daniel-Henri Caignard, Jean-Francois Renaud de la Faverie, Gerard Adam
  • Patent number: 5393775
    Abstract: A compound selected from those of formula (I): ##STR1## in which R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7, R.sub.8, R.sub.9 and n are as defined in the description, its optical isomers, and its addition salts thereof with a pharmaceutically-acceptable acid or base,and medicinal product containing the same for treating a mammal afflicted with a disorder connected with peroxydation processes and biosynthesis of eicosanoids.
    Type: Grant
    Filed: September 7, 1993
    Date of Patent: February 28, 1995
    Assignee: Adir et Compagnie
    Inventors: Guillaume Le Baut, Jean-Paul Babingui, Sylvie Robert-Piessard, Pierre Renard, Daniel-henri Caignard, jean-Francois Renaud de la Faverle, Gerard Adam
  • Patent number: 5389668
    Abstract: The invention relates to compounds of the formula I: ##STR1## in which R.sub.1 is as defined in the description, their optical isomers and their addition salts with a pharmaceutically-acceptable acid or base, and medicinal products which are useful for treating Central Nervous System disorders.
    Type: Grant
    Filed: January 12, 1994
    Date of Patent: February 14, 1995
    Assignee: Adir Et Compagnie
    Inventors: Gerald Guillaumet, Gerard Coudert, Tchao Podona, Beatrice Guardiola-Lemaitre, Pierre Renard, Gerard Adam, Daniel Henri-Caignard