Abstract: An implantable medical device (IMD) includes one or more stimulation engines (SEs) and selectively connectable output switching circuitry for driving a plurality of output nodes associated with a respective plurality of electrodes of the IMD's lead system when implanted in a patient. The output switching circuitry may be configured to facilitate self-test mode (STM) functionality in the IMD (e.g., when it is in a hermetically sealed package) by using a dual mode switch in series with a stimulation engine selection switch with respect to each output node in the output switching circuitry under mode selection control.

Abstract: An implantable medical device (IMD) includes multiple stimulation engines for independently stimulating respective electrode sets of a lead system while avoiding collisions and/or channel contention during stimulation delivery. A first voltage multiplier is configured to generate an adjustable target voltage having sufficient headroom at an output node that is commonly coupled to anodic nodes of respective stimulation engines. Each stimulation engine includes a secondary voltage multiplier to drive the respective anode and a current regulator powered by a floating voltage supply, wherein the current regulator is coupled to a cathodic node and configured to control how much stimulation current is pulled from the patient tissue.

Abstract: A neurostimulation (NS) system and method are provided. The NS system includes an array of electrodes positioned within a patient. The array of electrodes includes an active electrode. The active electrode is configured to be a cathode electrode located proximate to neural tissue of interest that is associated with a target region. The NS system includes an anode electrode and an electromagnetic interference (EMI) antenna. A control circuit is configured to control delivery of a NS therapy during a therapy delivery interval. The NS therapy is to be delivered between the anode electrode and the active electrode. The NS system develops a residual voltage between the anode electrode and the active electrode over the therapy delivery interval. A current regulator (CR) circuit is connected to the cathode electrode. The CR circuit is configured to control current flow through the cathode electrodes.

Abstract: A system and method are provided that include a power supply having positive and negative terminals. The negative terminal defines a reference ground. First and second electrodes are positioned within a patient and configured to be located proximate to tissue of interest that is associated with a target region. A control circuit is configured to control delivery of current for a therapy between the first and second electrodes. A current regulator (CR) circuit is connected to, and configured to control current flow through, at least the first electrode during delivery of the therapy under direction of the control circuit. A floating power supply is connected across power supply terminals of the CR circuit. The CR circuit and floating power supply are coupled to a floating ground node that is electrically separate from the reference ground.

Abstract: Provided is an implantable pulse generator (IPG) that includes a controller, and stimulation circuitry for generating electrical pulses to stimulate neural tissue of the patient. The IPG also includes a static random-access memory (SRAM) component for storing data to control the generating of the electrical pulses, wherein the SRAM component is connected to at least the controller through a first interface bus at a first word width and is connected to at least the stimulation circuitry through a second interface bus at a second word width. The SRAM component comprises column select logic that decodes read or write (R/W) access from the controller and provides for selective connection of each column of the SRAM component to the first interface bus during the R/W access, or to the second interface bus during stimulation operations to provide stimulation control data to components of the stimulation circuitry.

Abstract: Provided is an implantable pulse generator (IPG) for providing electrical pulses to a patient during neurostimulation therapy. The IPG includes a controller for controlling operations of the IPG, a battery for powering the IPG, a therapeutic stimulation circuitry for generating electrical pulses to stimulate neural tissue of the patient, and internal diagnostic circuitry for digitizing device signals to control operations of the IPG. The internal diagnostic circuitry includes a multi-stage comparator including a pre-amplifier configured to receive an analog input signal and convert the analog input signal into a first analog output signal and second analog output signal. The multi-stage comparator also including a first latch circuit with a first receiving device that receives the first analog output signal, a second receiving device that receives the second analog output signal, and configured to convert the first analog output signal and second analog output signal into a digital output signal.

Abstract: System and methods for providing a pulsed therapy comprises an implantable pulse generator (IPG) having circuitry configured to control generation and delivery of electrical pulses using at least one electrode of a stimulation lead. The IPG further comprises memory configured to store program instructions and one or more processors configured to execute the program instructions. The one or more processors are configured to deliver the pulses, having a corresponding pulse duration and an amplitude, to the at least one electrode. The amplitude can vary over the pulse duration of at least one of the pulses. The processor(s), monitor a signal indicative of a present level of the amplitude of the at least one pulse, and based on the signal, declare a pulse valid based on the present level satisfying an initial criteria for at a sub-duration of the pulse duration that is less than an entire pulse duration.

Abstract: A neurostimulation (NS) system and method are provided. The NS system includes an array of electrodes positioned within a patient. The array of electrodes includes an active electrode. The active electrode is configured to be a cathode electrode located proximate to neural tissue of interest that is associated with a target region. The NS system includes an anode electrode and an electromagnetic interference (EMI) antenna. A control circuit is configured to control delivery of a NS therapy during a therapy delivery interval. The NS therapy is to be delivered between the anode electrode and the active electrode. The NS system develops a residual voltage between the anode electrode and the active electrode over the therapy delivery interval. A current regulator (CR) circuit is connected to the cathode electrode. The CR circuit is configured to control current flow through the cathode electrodes.

Abstract: A system and method are provided that include a power supply having positive and negative terminals. The negative terminal defines a reference ground. First and second electrodes are positioned within a patient and configured to be located proximate to tissue of interest that is associated with a target region. A control circuit is configured to control delivery of current for a therapy between the first and second electrodes. A current regulator (CR) circuit is connected to, and configured to control current flow through, at least the first electrode during delivery of the therapy under direction of the control circuit. A floating power supply is connected across power supply terminals of the CR circuit. The CR circuit and floating power supply are coupled to a floating ground node that is electrically separate from the reference ground.

Abstract: A system and method for measuring and monitoring charge states of one or more electrodes of an implanted stimulation lead system associated with an IPG. A Kelvin connection scheme operative with a switching circuit is provided for coupling select electrode terminals disposed in a Kelvin connection measurement loop in a switchable manner to sense and reference inputs of an analog-to-digital converter (ADC) configured as at least part of diagnostic circuitry for the IPG.

Abstract: An implantable medical device (IMD) includes an adjustable capacitive voltage multiplier (CVM) that is responsive to diagnostic circuitry configured to provide control signals within a single stimulation current pulse for adjusting the voltage output applied to an electrode of the IMD's lead system. A control counter is coupled to the diagnostic circuitry for incrementing or decrementing an N-bit counter output signal operative to reconfigure a charge pump arrangement of the CVM so as to facilitate an adjusted voltage output.

Abstract: A system and method for measuring and monitoring charge states of one or more electrodes of an implanted stimulation lead system associated with an IPG. A Kelvin connection scheme operative with a switching circuit is provided for coupling select electrode terminals disposed in a Kelvin connection measurement loop in a switchable manner to sense and reference inputs of an analog-to-digital converter (ADC) configured as at least part of diagnostic circuitry for the IPG.

Abstract: Pulse pattern detecting circuitry for use with a fractional voltage multiplier of a neurostimulation system is provided. The pulse pattern detecting circuitry is configured to detect an initial overlap of a repeating pulse pattern, wherein the repeating pulse pattern is generated by a plurality of pulse engines that generate pulses at different frequencies, the initial overlap occurring when pulses generated by each of the plurality of pulse engines occur simultaneously, detect a subsequent overlap of the repeating pulse pattern, the subsequent overlap of the pulse pattern occurring when pulses generated by each of the plurality of pulse engines again occur simultaneously, detect a plurality of events between the initial overlap and the subsequent overlap, each event corresponding to at least one of the plurality of pulse engines generating a pulse, and record a voltage multiplier setting for each of the plurality of detected events.

Abstract: An implantable medical device (IMD) configured to provide stimulation therapy using an instruction set architecture (ISA) includes a main processor operating at a first frequency and a secondary processor operating at a second frequency lower than the first frequency. Example ISA may comprise assembly-language-like instructions that may be executed by the secondary processor for configuring one or more stimulation engines (SEs) to cause stimulation of select electrode sets of a lead system based on one or more pulse definitions and one or more timing definitions corresponding to a therapy program selection effectuated by a user at an external device.

Abstract: An implantable medical device (IMD) includes one or more stimulation engines (SEs) and selectively connectable output switching circuitry for driving a plurality of output nodes associated with a respective plurality of electrodes of the IMD's lead system when implanted in a patient. The output switching circuitry may be configured to facilitate self-test mode (STM) functionality in the IMD (e.g., when it is in a hermetically sealed package) by using a dual mode switch in series with a stimulation engine selection switch with respect to each output node in the output switching circuitry under mode selection control.

Abstract: An implantable medical device (IMD), includes a processor for controlling the IMD; circuitry for providing therapeutic or diagnostic medical operations for a patient; wireless communication circuitry for conducting wireless communications; a non-rechargeable battery; and device power control circuitry. The device power control circuitry includes at least one capacitor; charging control circuitry for switching between charging the at least one capacitor using the non-rechargeable battery and discharging the at least one capacitor to provide power for device operations. The IMD is configured to maintain a count related to a number of times of discharge of the at least one capacitor to provide an end-of-life estimation for the non-rechargeable battery.

Abstract: The present disclosure provides systems and methods for circuitry for an implantable pulse generator (IPG) of a neurostimulation system. The circuitry includes at least one anode node, at least one cathode node, a plurality of switching circuits, each switching circuit coupled to the at least one anode node and the at least one cathode node, and a plurality of output channels, each output channel coupled between an associated switching circuit and at least one electrode. The circuitry further includes a first DC blocking capacitor coupled between the at least one anode node and the plurality of switching circuits, a second DC blocking capacitor coupled between the at least one cathode node and the plurality of switching circuits. The circuitry further includes mitigation circuitry operable to limit DC leakage from the plurality of switching circuits through the plurality of output channels.

Abstract: The present disclosure provides systems and methods for providing neurostimulation therapy according to patient features. The patient features may be analyzed to develop a patient model between physiological and/or patient reported features and optimal settings for a neurostimulation therapy using machine learning operations. The model is used to control ongoing neurostimulation therapy for the patient.

Abstract: The present disclosure provides systems and methods for an output architecture for an implantable pulse generator of a neurostimulation system. The output architecture includes a power supply, a plurality of outputs, a global source current regulator coupled to the power supply and operable to source current from the power supply to the plurality of outputs through a plurality of source current branches, a global sink current regulator operable to sink current from the plurality of outputs to ground through a plurality of sink current branches, a current source branch selector operable to select, for each of the plurality of outputs, an amount of current sourced from the plurality of source current branches, and a current sink branch selector operable to select, for each of the plurality of outputs, an amount of current sunk to the plurality of sink current branches.

Abstract: The present disclosure provides systems and methods for generating waveforms for an implantable pulse generator of a neurostimulation system. A waveform generation system includes a computing device, at least one buffer memory, and at least one programmable current regulator. The at least one buffer memory is coupled between the computing device and the at least one programmable current regulator. The computing device is configured to load a string of output current values into the at least one buffer memory, and the at least one buffer memory is configured to sequentially feed each output current value to the at least one programmable current regulator. Further, the at least one programmable current regulator is configured to control current supplied to a plurality of electrodes based on the received output current values.