Abstract: A light emitting device (100) comprises a light source (114) mounted in a housing (112), a lens (122) through which light from the source (114) is emitted from the housing (112), and a filter (126) arranged between the light source (114) and the lens (122) to filter the emitted light, the filter (126) being of dichroic type and the lens (122) being asymmetric. The light emitting device (100) may comprise a plurality of light sources (114) and/or the filter (126) may be adapted to transmit perpendicularly incident light and to at least partially reflect obliquely incident light.

Abstract: Phosphatidylinositol (PI) 3-kinase inhibitor compounds, their pharmaceutically acceptable salts, and prodrugs thereof; compositions of the new compounds, either alone or in combination with at least one additional therapeutic agent, with a pharmaceutically acceptable carrier; and uses of the new compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of proliferative diseases characterized by the abnormal activity of growth factors, protein serine/threonine kinases, and phospholipid kinases.

Abstract: Compounds of formula I in free or salt form, wherein R1, R2, R3, R4 and X have the meanings as indicated in the specification, are useful for treating diseases mediated by phosphatidylinositol 3-kinase. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.

Abstract: Phosphatidylinositol (PI) 3 kinase inhibitor compounds, their pharmaceutically acceptable salts, and prodrugs thereof; compositions of the new compounds, either alone or in combination with at least one additional therapeutic agent, with a pharmaceutically acceptable carrier; and uses of the new compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of proliferative diseases characterized by the abnormal activity of growth factors, protein serine/threonine kinases, phospholipid kinases, G-protein coupled receptors, and phosphatases.

Abstract: A blast movement monitor for measuring the movement of material within a body of material as a result of a blasting operation, the monitor including: a housing having an interior chamber defining an inner surface; and an internal communication device that is received immediately within the interior chamber of the housing and which is adapted to transmit a signal to an external communication device and/or to detect a signal transmitted by the external communication device; wherein the internal communication device includes a body portion and opposing end portions, the end portions being configured such that they are complementary with the inner surface of the interior chamber and the internal communication device being biased to facilitate self-righting of the internal communication device to a desired orientation within the interior chamber independent of the orientation of the monitor.

Abstract: The present invention concerns a compound of formula Ia wherein: Ra* is hydrogen or C1-4-alkyl; Rb* is —(C1-C4-alkylene)-Y—C1-4-haloalkyl or —(C1-C4-alkylene)-Y—C1-C4-hydroxyalkyl; Y represents —CONH— or a five membered heteroaryl group.

Abstract: The invention describes novel pharmaceutically acceptable salt forms of camostat, processes for lyophilisation, taste-masked formulations, nebulised formulations and the use of each of the fore-going in the treatment of respiratory diseases, particularly cystic fibrosis and chronic obstructive pulmonary disease (COPD).

Abstract: A system for information capture for use in an environment comprising a plurality of nodes, wherein a node communicates with another node via an electronic message and wherein expertise information is associated with a first set of the plurality of nodes. The system comprises means for receiving an input comprising expertise information, means for determining the first set of the plurality of nodes associated with expertise information, means for aggregating a second set of a plurality of nodes of the first set, wherein each node in the second set is associated with the expertise information and communicates with another node in the second set via an electronic message and means for generating a visual representation from information associated with: the second set of a plurality of nodes and the electronic messages associated with the second set of a plurality of nodes.

Abstract: A context enhanced messaging and collaboration system in which resources related to the context of text messages may be automatically identified and exchanged between users in association with the text messages, is provided. A graphical user interface (GUI) is provided for instant messaging between client devices. The GUI operates in conjunction with a context analysis engine that automatically analyzes the context of the textual messages being exchanged between the users and retrieves resources that correspond to the detected context. Representations of these automatically identified resources may be presented to the user via the GUI. The user of the GUI may enter text messages into the GUI and may select individual ones of the retrieved resources for transmission in association with the text messages. Furthermore, an automated mechanism may be used to select resources to attach to individual text messages entered by the user.

Abstract: A method for measuring the movement of boundaries between different portions of a heterogeneous rock body is disclosed. The method comprises placing a plurality of blast movement monitors 109 in a rock body prior to blasting and noting the position of each blast movement monitor. The rock body is then blasted to break it up into a plurality of pieces. Thereafter the position of the blast movement monitors 109 is located and based on this the boundaries of rock portions can be adjusted to account for the blast. This leads to a more accurate reporting of different ore bodies to the appropriate processor in a heterogeneous rock body. An apparatus for carrying out the method is also disclosed. The apparatus comprises broadly a said monitor 109 and a receiver. The monitor 1 comprises a transmitter 109 received within a casing 111 that in turn is received within a housing 126. Further the casing 111 can move within the housing 126 and self right so that it always transmits its signal in an upright direction.

Abstract: A computer implemented method of information capture is provided. Each node in a knowledge network associated with a first piece of expertise information that communicates with at least one other node associated with the first piece of expertise information is aggregated to form a first expertise network. Each node in the first expertise network associated with a second piece of expertise information that communicates with at least one other node associated with the second piece of expertise information is aggregated to form a second expertise network. Visual representations of the knowledge network, the first expertise network, and the second expertise network are generated. Trends and patterns are determined using the visualization of the knowledge network, the visualization of the first expertise network, and the visualization of the second expertise network.

Abstract: Compounds of formula I in free or salt form, wherein R1, R2, R3, R4 and X have the meanings as indicated in the specification, are useful for treating diseases mediated by phosphatidylinositol 3-kinase. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.

Abstract: in free or salt form, wherein Ra, Rb, R2, R3, R4 and R5 have the meanings as indicated in the specification, are useful for treating conditions that are mediated by mediated by phosphatidylinositol 3-kinase. Pharmaceutical compositions that contain the compounds and a process for preparing the compounds are also described.

Abstract: An apparatus, system, and method are disclosed for an inline display of related blog postings. The apparatus, system, and method include searching a first blog for material common to the first blog and to a second blog and adding a link to the common material in the second blog. The link includes an interactive indicator in the second blog that displays a posting from the first blog that contains the common material in response to selection of the indicator. The apparatus, system, and method include marking each posting in the first blog that contains the common material and that has been displayed in the second blog as having been read.

Abstract: An audio broadcast creation client applies the concept of style sheets to audio data intended for audio broadcasts. The creation client associates style sheet elements to sections of the audio broadcast. An audio broadcast rendering engine applies the style sheet elements at runtime to alter or enhance sections of the audio broadcast. Different style sheets may be applied to the same raw audio broadcast data to alter the end result. A template is provided for generating audio broadcasts. The user may record the appropriate audio files and refer to these audio files in fields of the audio broadcast template.

Abstract: A kit and method for assembling an item, such as assembly-required furniture, is provided. The kit includes a plurality of parts and a plurality of compartments for packaging the parts. The parts packaged in a first compartment are used in a first assembly step, and the parts packaged in a second compartment are used in a second assembly step. This kit and method may be used to simplify the process of assembling various types of items such as furniture, toys, games and decorations as well as other various assembly-required items.

Abstract: A method for measuring the movement of boundaries between different portions of a heterogeneous rock body is disclosed. The method comprises placing a plurality of blast movement monitors 109 in a rock body prior to blasting and noting the position of each blast movement monitor. The rock body is then blasted to break it up into a plurality of pieces. Thereafter the position of the blast movement monitors 109 is located and based on this the boundaries of rock portions can be adjusted to account for the blast. This leads to a more accurate reporting of different ore bodies to the appropriate processor in a heterogeneous rock body. An apparatus for carrying out the method is also disclosed. The apparatus comprises broadly a said monitor 109 and a receiver. The monitor 1 comprises a transmitter 109 received within a casing 111 that in turn is received within a housing 126. Further the casing 111 can move within the housing 126 and self right so that it always transmits its signal in an upright direction.

Abstract: Compounds of formula I in free or salt form, wherein Ar, R1, R2, R3, X and T have the meanings as indicated in the specification, are useful for treating a condition mediated by CCR-3, particularly an inflammatory or allergic condition such as an inflammatory or obstructive airways disease. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.

Abstract: An apparatus for managing outputs of a first application and a second application is provided. Each application is operable to execute on a data processing system and output of the first application is executed on the data processing system. The apparatus comprises a classifier for associating the first application and the second application with classification data, wherein the classification data is stored in a classification data structure; a comparator for comparing the classification data associated with the first application and the second application with the classification data structure to determine a priority; and a generator, responsive to determination of the priority, for generating metadata associated with at least one of: the output of the first application and the output of the second application.

Abstract: A process of dispersing at least one pigment into a carrier such as castor oil or a vegetable wax such as palm oil glyceride wax. The resulting dispersion exhibits excellent color development and is fluid at room temperature. Suitable pigments include FD&C, D&C and inorganic pigments.