Patents by Inventor Darrin Anthony Lindhout

Darrin Anthony Lindhout has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods of use for treating metabolic disorders
    Patent number: 10562965
    Abstract: A complex comprising a GDF15 polypeptide is described. Methods of treating individuals with a metabolism disorder, such as, glucose metabolism disorder and/or a body weight disorder, and compositions associated therewith, are provided.
    Type: Grant
    Filed: January 31, 2018
    Date of Patent: February 18, 2020
    Assignee: NGM Biopharmaceuticals, Inc.
    Inventors: Wenyan Shen, Darrin Anthony Lindhout, Raj Haldankar, Hugo Matern
  • Pharmaceutical compositions comprising FGF19 variants
    Patent number: 10517929
    Abstract: Provided herein are pharmaceutical compositions, formulations and dosage forms comprising variants of fibroblast growth factor 19 (FGF19) proteins and peptide sequences (and peptidomimetics) and fusions of FGF19 and/or fibroblast growth factor 21 (FGF21) proteins and peptide sequences (and peptidomimetics), and variants of fusions of FGF19 and/or FGF21 proteins and peptide sequences (and peptidomimetics). Methods of using the pharmaceutical compositions, formulations and dosage forms are also provided herein.
    Type: Grant
    Filed: October 22, 2015
    Date of Patent: December 31, 2019
    Assignee: NGM Biopharmaceuticals, Inc.
    Inventors: Darrin Anthony Lindhout, Charles V. Olson
  • Methods of using compositions comprising variants of FGF19 polypeptides for reducing body mass in a subject
    Patent number: 10413590
    Abstract: The invention relates to methods of using variants of fibroblast growth factor 19 (FGF19) for reducing body mass in a subject.
    Type: Grant
    Filed: August 1, 2017
    Date of Patent: September 17, 2019
    Assignee: NGM Biopharmaceuticals, Inc.
    Inventors: Lei Ling, Darrin Anthony Lindhout
  • Compositions comprising variants of FGF19 polypeptides and uses thereof for the treatment of hyperglycemic conditions
    Patent number: 10398758
    Abstract: Provided herein are variants and fusions of fibroblast growth factor 19 (FGF19), variants and fusions of fibroblast growth factor 21 (FGF21), fusions of FGF19 and/or FGF21, and variants or fusions of FGF19 and/or FGF21 proteins and peptide sequences (and peptidomimetics), having one or more activities, such as glucose lowering activity, and methods for and uses in treatment of hyperglycemia and other disorders.
    Type: Grant
    Filed: May 27, 2015
    Date of Patent: September 3, 2019
    Assignee: NGM Biopharmaceuticals, Inc.
    Inventors: Lei Ling, Darrin Anthony Lindhout
  • Compositions and Methods of Use for Treating Metabolic Disorders
    Publication number: 20190183974
    Abstract: Methods of treating individuals with a glucose metabolism disorder and/or a body weight disorder, and compositions associated therewith, are provided.
    Type: Application
    Filed: December 14, 2018
    Publication date: June 20, 2019
    Inventors: Darrin Anthony Lindhout, Peng Zhang, Thomas Frederick Parsons
  • Compositions and methods of use for treating metabolic disorders
    Patent number: 10323075
    Abstract: Methods of treating individuals with a glucose metabolism disorder and/or a body weight disorder, and compositions associated therewith, are provided.
    Type: Grant
    Filed: October 20, 2017
    Date of Patent: June 18, 2019
    Assignee: NGM Biopharmaceuticals, Inc.
    Inventors: Hugo Matern, Darrin Anthony Lindhout, Raj Haldankar, Geoffrey Horner
  • COMPOSITIONS COMPRISING VARIANTS AND FUSIONS OF FGF19 POLYPEPTIDES
    Publication number: 20190177384
    Abstract: The invention relates to variants and fusions of fibroblast growth factor 19 (FGF19), variants and fusions of fibroblast growth factor 21 (FGF21), fusions of fibroblast growth factor 19 (FGF19) and/or fibroblast growth factor 21 (FGF21), and variants or fusions of fibroblast growth factor 19 (FGF19) and/or fibroblast growth factor 21 (FGF21) proteins and peptide sequences (and peptidomimetics), having one or more activities, such as glucose lowering activity, and methods for and uses in treatment of hyperglycemia and other disorders.
    Type: Application
    Filed: December 11, 2018
    Publication date: June 13, 2019
    Inventors: Lei Ling, Darrin Anthony Lindhout
  • Compositions and methods of use for treating metabolic disorders
    Patent number: 10195250
    Abstract: Methods of treating individuals with a glucose metabolism disorder and/or a body weight disorder, and compositions associated therewith, are provided.
    Type: Grant
    Filed: December 13, 2016
    Date of Patent: February 5, 2019
    Assignee: NGM Biopharmaceuticals, Inc.
    Inventors: Darrin Anthony Lindhout, Peng Zhang, Thomas Frederick Parsons
  • Compositions Comprising Variants and Fusions of FGF19 Polypeptides
    Publication number: 20180355007
    Abstract: The invention relates to variants and fusions of fibroblast growth factor 19 (FGF19), variants and fusions of fibroblast growth factor 21 (FGF21), fusions of fibroblast growth factor 19 (FGF19) and/or fibroblast growth factor 21 (FGF21), and variants or fusions of fibroblast growth factor 19 (FGF19) and/or fibroblast growth factor 21 (FGF21) proteins and peptide sequences (and peptidomimetics), having one or more activities, such as glucose lowering activity, and methods for and uses in treatment of hyperglycemia and other disorders.
    Type: Application
    Filed: June 25, 2018
    Publication date: December 13, 2018
    Inventors: Lei Ling, Darrin Anthony Lindhout
  • Compositions and Methods of Use for Treating Metabolic Disorders
    Publication number: 20180237514
    Abstract: A complex comprising a GDF15 polypeptide is described. Methods of treating individuals with a metabolism disorder, such as, glucose metabolism disorder and/or a body weight disorder, and compositions associated therewith, are provided.
    Type: Application
    Filed: January 31, 2018
    Publication date: August 23, 2018
    Inventors: Wenyan Shen, Darrin Anthony Lindhout, Raj Haldankar, Hugo Matern
  • Compositions and Methods of Use for Treating Metabolic Disorders
    Publication number: 20180134761
    Abstract: Methods of treating individuals with a glucose metabolism disorder and/or a body weight disorder, and compositions associated therewith, are provided.
    Type: Application
    Filed: November 1, 2017
    Publication date: May 17, 2018
    Inventors: Darrin Anthony Lindhout, Raj Haldankar, Hui Tian, Jer-Yuan Hsu
  • Methods of using compositions comprising variants and fusions of FGF19 polypeptides for reducing glucose levels in a subject
    Patent number: 9963494
    Abstract: The invention relates to variants and fusions of fibroblast growth factor 19 (FGF19), variants and fusions of fibroblast growth factor 21 (FGF21), fusions of FGF19 and/or FGF21, and variants or fusions of FGF19 and/or FGF21 proteins and peptide sequences (and peptidomimetics), having one or more activities, such as glucose lowering activity, and methods for and uses in treatment of hyperglycemia and other disorders.
    Type: Grant
    Filed: November 26, 2013
    Date of Patent: May 8, 2018
    Assignee: NGM Biopharmaceuticals, Inc.
    Inventors: Lei Ling, Darrin Anthony Lindhout
  • Compositions and Methods of Use For Treating Metabolic Disorders
    Publication number: 20180100003
    Abstract: Methods of treating individuals with a glucose metabolism disorder and/or a body weight disorder, and compositions associated therewith, are provided.
    Type: Application
    Filed: October 20, 2017
    Publication date: April 12, 2018
    Inventors: Hugo Matern, Darrin Anthony Lindhout, Raj Haldankar, Geoffrey Horner
  • Compositions and methods of use for treating metabolic disorders
    Publication number: 20180099025
    Abstract: Methods of treating individuals with a glucose metabolism disorder and/or a body weight disorder, and compositions associated therewith, are provided.
    Type: Application
    Filed: October 20, 2017
    Publication date: April 12, 2018
    Inventors: Hugo Matern, Darrin Anthony Lindhout, Raj Haldankar
  • Compositions and methods of use for treating metabolic disorders
    Patent number: 9920118
    Abstract: A complex comprising a GDF15 polypeptide is described. Methods of treating individuals with a metabolism disorder, such as, glucose metabolism disorder and/or a body weight disorder, and compositions associated therewith, are provided.
    Type: Grant
    Filed: October 29, 2015
    Date of Patent: March 20, 2018
    Assignee: NGM Biopharmaceuticals, Inc.
    Inventors: Wenyan Shen, Darrin Anthony Lindhout, Raj Haldankar, Hugo Matern
  • Compositions and methods of use for treating metabolic disorders
    Patent number: 9834586
    Abstract: Methods of treating individuals with a glucose metabolism disorder and/or a body weight disorder, and compositions associated therewith, are provided.
    Type: Grant
    Filed: July 28, 2015
    Date of Patent: December 5, 2017
    Assignee: NGM Biopharmaceuticals, Inc.
    Inventors: Darrin Anthony Lindhout, Raj Haldankar, Hui Tian, Jer-Yuan Hsu
  • Compositions and methods of use for treating metabolic disorders
    Patent number: 9828415
    Abstract: Methods of treating individuals with a glucose metabolism disorder and/or a body weight disorder, and compositions associated therewith, are provided.
    Type: Grant
    Filed: January 27, 2014
    Date of Patent: November 28, 2017
    Assignee: NGM Biopharmaceuticals, Inc.
    Inventors: Hugo Matern, Darrin Anthony Lindhout, Raj Haldankar, Geoffrey Horner
  • Compositions and methods of use for treating metabolic disorders
    Patent number: 9827291
    Abstract: Methods of treating individuals with a glucose metabolism disorder and/or a body weight disorder, and compositions associated therewith, are provided.
    Type: Grant
    Filed: September 4, 2015
    Date of Patent: November 28, 2017
    Assignee: NGM Biopharmaceuticals, Inc.
    Inventors: Hugo Matern, Darrin Anthony Lindhout, Raj Haldankar
  • METHODS OF USING COMPOSITIONS COMPRISING FUSION VARIANTS OF FGF19 POLYPEPTIDES FOR REDUCING GLUCOSE LEVELS IN A SUBJECT
    Publication number: 20170327551
    Abstract: The invention relates to variants and fusions of fibroblast growth factor 19 (FGF19), variants and fusions of fibroblast growth factor 21 (FGF21), fusions of fibroblast growth factor 19 (FGF19) and/or fibroblast growth factor 21 (FGF21), and variants or fusions of fibroblast growth factor 19 (FGF19) and/or fibroblast growth factor 21 (FGF21) proteins and peptide sequences (and peptidomimetics), having one or more activities, such as glucose lowering activity, and methods for and uses in treatment of hyperglycemia and other disorders.
    Type: Application
    Filed: August 1, 2017
    Publication date: November 16, 2017
    Inventors: Lei LING, Darrin Anthony LINDHOUT
  • Methods of using compositions comprising fusion variants of FGF19 polypeptides for reducing glucose levels in a subject
    Patent number: 9751924
    Abstract: The invention relates to methods for and uses in reducing glucose levels in subjects in need thereof with variants and fusions of fibroblast growth factor 19 (FGF19) proteins and peptide sequences (and peptidomimetics).
    Type: Grant
    Filed: December 29, 2015
    Date of Patent: September 5, 2017
    Assignee: NGM Biopharmaceuticals, Inc.
    Inventors: Lei Ling, Darrin Anthony Lindhout