Abstract: A self-wrapping, non-woven sleeve for routing and protecting elongate members and method of construction thereof is provided. The sleeve includes an elongate non-woven wall having opposite sides extending along a longitudinal axis of the sleeve. The sides are self-wrapping about the longitudinal axis to provide a tubular cavity. The sides are extendable away from one another under an externally applied force to expose the cavity for insertion of the elongate members, wherein the sides return to their self-wrapped configuration upon removal of the externally applied force. The wall includes discrete first regions of a material and discrete second regions of a material. The first and second regions of material are different and provide the wall with non-uniform physical properties.

Abstract: A liquid suspension comprising an antifungally effective amount of the micronized compound represented by the chemical structural formula I: at least one thickening agent, a non-ionic surfactant, and a pharmaceutically acceptable liquid carrier is disclosed.

Abstract: A system for generating electrical energy from ambient energy such as the energy of ambient motion and acoustic vibrations. The system has at least two stages, a resonating electrical generator and a kinetic energy conversion system. The stages have differing resonant frequencies to enable harvesting energy from lower frequency ambient motion and converting the energy to higher frequency resonant oscillation for efficiently generating electrical energy. A multiaxial system having a plurality of systems for generating electrical energy from ambient motion each oriented to be responsive to motion along a different axis. An embodiment of a system for generating electrical energy from ambient motion for which the resonating electrical generator is at least part of a driving mass of the kinetic energy conversion system.

Abstract: Dry powder inhalers are described with an inhaler body defining an enclosed cavity space and at least one of (a) an endless strip having opposing primary surfaces, the strip comprising a plurality of spaced apart blisters or dose containers holding dry powder medicament. The inhaler also has an inhalation exit flow path in the inhaler body in communication with at least one blister or at least one dose container held by the strip in a dispensing position and a piercer configured to release dry powder medicament from the blister or dose container in the dispensing position.

Abstract: A servicing daemon is described herein for providing servicing of a running computer system (such as a filer). The servicing daemon resides and executes on the operating system of the filer and communicates across a network with a debugger that resides and executes on a remote administering computer. A debugging session is performed that complies with a protocol relating to the remote accessing of files. The debugging session provides live servicing of an application executing on the filer without requiring an actual corefile (having copied filer memory data) to be created. Rather, the servicing daemon creates a simulated corefile header that is sent to the debugger, receives requests from the debugger, and maps addresses specified in the requests to filer memory addresses. The servicing daemon then reads and retrieves data directly from filer memory at the determined filer memory addresses and sends the data to the debugger for analysis.

Abstract: A locking fastener assembly comprising a nut and a washer. The nut and washer each have opposed load bearing surfaces which include a series of annularly extending, slightly inclined faces forming shallow undulations around each surface. The load bearing surface on the nut is generally spherically convex and the load bearing surface on the washer is generally spherically concave. The nut rotates as it is installed while the washer is prevented from rotating so that the undulating bearing surface on the nut slides over the undulating bearing surface on the washer against ever increasing resistance until the assembly is properly seated and the nut is effectively prevented from counter-rotating by interference between opposed, inclined faces. A concave clamping surface is formed on the outer end of the washer on a radially extending flange. The flange flexes when the assembly is installed and resiliently urges the washer against the nut.

Abstract: Methods are described for utilizing user-submitted data to provide a response to a query request. User-submitted data are received and referenced upon receiving a query request from an unregistered requester, a potential response is automatically identified from the user-submitted data, the potential response is extracted, and presented in response to the query request.

Abstract: Dry powder inhalers and methods are provided that facilitate deagglomeration of powdered medicament during inspiration. A dry powder inhaler includes a dry powder medicament container assembly, and an elongated dry powder delivery tube having an inlet at one end that communicates with a dose container, and an outlet or inhalation port that extends from the inhaler housing at an opposite end. The delivery tube includes one or more apertures adjacent the inlet that cause cyclonic or turbulent airflow through the delivery tube. The inner surface of the delivery tube has a polygonal configuration and the cyclonic air stream bounces off the polygonal inner surface numerous times as the air stream flows through the delivery tube. Another dry powder inhaler includes a deagglomeration chamber with a polygonal inner surface. An air stream containing dry powder medicament is directed into the deagglomeration chamber and impacts the polygonal inner surface numerous times.

Abstract: The present application provides novel compositions comprising posaconazole and a polymer wherein the composition has a glass transition temperature (Tg) of less than about 1100 C. The application also describes compositions comprising posaconazole and a polymer having a bulk density of greater than about 0.4 mg/mL. The application also describes compositions comprising posaconazole and a polymer which provide an exposure (AUCtf) of at least about 10,000 ng·hr/mL when administered to a patient in a fasted state. The application also describes a novel process for preparing these compositions. The preff erred polymer is HPMCAS. Preferably the composition is an extruded material.

Abstract: A method and apparatus for alerting a user of topical negative pressure therapy apparatus to a full waste canister condition are described, the apparatus comprising a device having vacuum pump means and a waste canister connected to the device and the waste canister operably connected to a wound dressing by aspiration conduit means for aspirating fluid from the wound, the aspiration conduit means, the waste canister and the device providing a fluid flow path therethrough and the vacuum pump means providing fluid flow through the apparatus, the apparatus further comprising fluid flow restriction means in the fluid flow path of said vacuum pump and fluid pressure sensing means upstream and downstream of said fluid flow restriction means.

Abstract: For optimizing resources for a parallel data integration job, a job request is received, which specifies a parallel data integration job to deploy in a grid. Grid resource utilizations are predicted for hypothetical runs of the specified job on respective hypothetical grid resource configurations. This includes automatically predicting grid resource utilizations by a resource optimizer module responsive to a model based on a plurality of actual runs of previous jobs. A grid resource configuration is selected for running the parallel data integration job, which includes the optimizer module automatically selecting a grid resource configuration responsive to the predicted grid resource utilizations and an optimization criterion.

Abstract: A method of forming a composite of embedded nanofibers in a polymer matrix is disclosed. The method includes incorporating nanofibers in a plastic matrix forming agglomerates, and uniformly distributing the nanofibers by exposing the agglomerates to hydrodynamic stresses. The hydrodynamic said stresses force the agglomerates to break apart. In combination or additionally elongational flow is used to achieve small diameters and alignment. A nanofiber reinforced polymer composite system is disclosed. The system includes a plurality of nanofibers that are embedded in polymer matrices in micron size fibers. A method for producing nanotube continuous fibers is disclosed. Nanofibers are fibrils with diameters of 100 nm, multiwall nanotubes, single wall nanotubes and their various functionalized and derivatized forms. The method includes mixing a nanofiber in a polymer; and inducing an orientation of the nanofibers that enables the nanofibers to be used to enhance mechanical, thermal and electrical properties.

Abstract: The present invention provides a solid molecularly dispersed composition comprising a poorly water soluble and weakly basic azole antifungal compound and a pH sensitive polymer, pharmaceutical compositions, comprising the solid molecularly dispersed composition of the invention and methods of treating and/or preventing a fungal infection in a patient in need thereof comprising orally administering a pharmaceutical composition comprising a composition of the invention to a patient in need thereof. Preferably the antifungal, compound is posaconazole, and the pH sensitive polymer is HPMCAS.

Abstract: A device for applying treatment, or therapy, to a body part directs air efficiently and effectively to the body part by using an air diverter. In particular, a device for treating a body part, such as a massager, has one or more treatment areas positioned to deliver treatment to the body part and an air blower having an air outlet that creates a flow of air in an outward direction from the air outlet. The air diverter is positioned to divert the flow of air to the one or more treatment areas.

Abstract: A system for controlling selection of filters for protecting against vulnerabilities of a computer network includes a vulnerability management system analyzes the computer network and determines network vulnerabilities for the computer network. The vulnerability management system is configured to receive real-time data on a status of filters protecting against vulnerabilities of the computer network. A database contains a pre-generated mapping of network vulnerabilities to filters for protecting against the network vulnerabilities. The vulnerability management system enables user control of filters for protecting against vulnerabilities of the computer network based upon the determined network vulnerabilities of the computer network, the pre-generated mapping of network vulnerabilities to the filters for protecting against the network vulnerabilities and the real-time data on the status of the filters.

Abstract: This invention relates to a load management controller for a household electrical installation comprising a plurality of electrical sub-circuits. The electrical sub-circuits may each comprise a plurality of components, a single component or a part of a single component. A plurality of the electrical sub-circuits have electricity usage profiles containing rules determining the supply of electricity to the electrical sub-circuit. The load management controller has access to the electricity usage profiles of the electrical sub-circuits and controls the supply of electricity to the electrical sub-circuit in accordance with the electricity usage profile related to that electrical sub-circuit. The household electrical installation may comprise a rechargeable battery bank or supply that may be used to provide power to the household electrical installation.

Abstract: The present invention relates to a load management controller for a household electrical installation comprising a pair of electricity supplies, a grid supply and a micro-generator supply, providing electricity to a plurality if sub-circuits. The household electrical installation has means to monitor the amount of electricity being supplied by the micro-generator supply and the amount of electricity being consumed in the household. The load management controller has means to access and use that information to control the supply of electricity to an energy storage sub-circuit to route surplus electricity supplied by the micro-generator to the energy storage sub-circuit. Furthermore, the load management controller can communicate with a remote electricity supplier to control the loads in the household to achieve better grid management and efficiency.

Abstract: A system and method of hosting a plurality of trading algorithms on an exchange is provided. The method includes an exchange server that receives an algorithm for trading orders from a user and associates the algorithm with the user in a database. The exchange server receives a marked order having information for associating the marked order with the algorithm, selects the algorithm associated with the user, receives market data from a market data feed, and executes the marked order according to the selected algorithm and the market data. The system includes an exchange server, rule container and rule database configured to execute the above-noted method.

Abstract: The invention provides for a process for preparing a urea grease including: (a) introducing a first feed component to a first feeding zone; (b) introducing a second feed component to a second feeding zone; (c) first reacting-mixing in a first reacting-mixing zone; and (d) cooling-mixing in a cooling-mixing zone. The invention also provides for a process for preparing a urea grease including: (a) introducing a first feed component to a first feeding zone; (b) introducing a second feed component to a second feeding zone; (c) first reacting-mixing in a first reacting-mixing zone; (d) introducing a third feed component to a third feeding zone; (e) second reacting-mixing in a second reacting-mixing zone; and (f) cooling-mixing in a cooling-mixing zone. The invention also provides for an apparatus for preparing a urea grease comprising: (a) a first feeding zone; (b) a second feeding zone; (c) a first reacting-mixing zone; and (d) a cooling-mixing zone.