Abstract: Disclosed herein are biopolymer-based coatings and products incorporating such coatings. Related methods and use are also provided.

Abstract: A method for generating three dimensional indicators for the visually impaired. The method includes selecting one or more pre-designed symbols from a plurality of pre-designed symbols. The pre-designed symbols represent standard building layout features and are sized to be readable via a physical touch. The method further includes inserting the one or more selected symbols into a two dimensional digital layout, and generating one or more of an orientation object and a legend object into the two dimensional digital layout. The method further includes converting the two dimensional digital layout into a three dimensional digital model, and generating an output file including the three dimensional model in a format compatible with a three dimensional printing device.

Abstract: A computing system may implement a split random number generator that may use a random number generator to generate and store seed values in a memory for retrieval and use by one or more core processors to generate random numbers for secure processes within each core processor.

Abstract: The disclosed system provides an adaptive control system technique generally related to distributed energy resources (DERs) located in distribution circuits. More specifically, the system technique relates to a DER with both active and reactive generation capability. In an embodiment, the system measures a voltage phase angle and a current phase angle of distribution feeder circuit, and measures a voltage value output by a power converter. The system calculates an active power setpoint value and a reactive power setpoint value of the power converter based on the measured voltage value, and the measured voltage phase angle and current phase angle. The system then sets the active and reactive power setpoint values on the power converter. The disclosed system automatically adjusts the setpoints to real-time load characteristics of the distribution feeder circuit, increases distribution feeder hosting capacity, and enables DERs to integrate in distribution feeders more efficiently.

Abstract: In some embodiments, the present invention provides methods for making resorbable ear tubes including the steps of providing a silk fibroin solution, and forming a silk ear tube from the silk fibroin solution, wherein the silk ear tube is less than 2 mm in length and has an outer diameter of less than 1.5 mm, and wherein the silk ear tube is resorbable. In some embodiments, the present invention also provides methods for treating otitis media including the step of introducing a silk ear tube into the ear canal of a subject, wherein the silk ear tube is less than 2 mm in length and has an outer diameter of less than 1.5 mm, and wherein the silk ear tube is resorbed by the subject.

Abstract: A method includes establishing an isolated execution environment for executing a platform firmware operating mode subroutine in a platform firmware operating mode. In response to receiving an interrupt, the platform firmware operating mode subroutine is executed in the isolated execution environment. In response to detecting an attempted access of a hardware resource resulting from execution of the platform firmware operating mode subroutine, the attempted access is blocked when the attempted access violates a security policy.

Abstract: The present disclosure provides binding agents, such as antibodies, that specifically bind ILT2, ILT4, or both ILT2 and ILT4, as well as compositions comprising the binding agents, and methods of their use. The disclosure also provides related polynucleotides and vectors encoding the binding agents and cells comprising the binding agents.

Abstract: Disclosed herein are biopolymer-based coatings and products incorporating such coatings. Related methods and use are also provided.

Abstract: Systems and devices for cooling and dispensing a beverage fluid are disclosed herein. One beverage dispensing system includes a beverage tower comprising a tower body, a shank, and a faucet. In some implementations, a coolant line is routed proximal to a beverage supply line through the tower body, through the shank, and into the faucet. In these and other implementations, the faucet includes a removable nozzle having a supplemental portion of the coolant line. In these and still other implementations, the faucet include a removable nozzle having a second coolant line. The coolant line and the second coolant line are configured to transport a coolant medium proximal to a beverage fluid in the beverage supply line to maintain or adjust the temperature of the beverage fluid. Many other features are described herein.

Abstract: The present disclosure provides binding agents, such as antibodies, that specifically bind ILT3, including human ILT3, as well as compositions comprising the binding agents, and methods of their use. The disclosure also provides related polynucleotides and vectors encoding the binding agents and cells comprising the binding agents.

Abstract: In some embodiments, the present invention provides methods for making resorbable ear tubes including the steps of providing a silk fibroin solution, and forming a silk ear tube from the silk fibroin solution, wherein the silk ear tube is less than 2 mm in length and has an outer diameter of less than 1.5 mm, and wherein the silk ear tube is resorbable. In some embodiments, the present invention also provides methods for treating otitis media including the step of introducing a silk ear tube into the ear canal of a subject, wherein the silk ear tube is less than 2 mm in length and has an outer diameter of less than 1.5 mm, and wherein the silk ear tube is resorbed by the subject.

Abstract: Systems and devices for cooling and dispensing a beverage fluid are disclosed herein. One beverage dispensing system includes a beverage tower comprising a tower body, a shank, and a faucet. In some implementations, a coolant line is routed proximal to a beverage supply line through the tower body, through the shank, and into the faucet. In these and other implementations, the faucet includes a removable nozzle having a supplemental portion of the coolant line. In these and still other implementations, the faucet include a removable nozzle having a second coolant line. The coolant line and the second coolant line are configured to transport a coolant medium proximal to a beverage fluid in the beverage supply line to maintain or adjust the temperature of the beverage fluid. Many other features are described herein.

Abstract: A virtualized computing environment is protected from a malicious hypervisor by restricting the hypervisor's access to one or more portions of an event (interrupt or exception) handling pathway of a guest virtual machine, wherein the guest virtual machine includes both a secure layer to manage security for the guest and one or more non-secure layers to handle event processing. The hypervisor is restricted from providing normal exception information to the guest virtual machine (referred to simply as a “guest” herein), and instead is only permitted to provide an event signal to the secure layer of the guest. In response to the event signal, the secure layer of the guest accesses a specified region of memory for the event information, reviews the information, and provides the information to another, non-secure, layer of the guest for processing only if the event information complies with specified security protocols.

Abstract: The present disclosure provides binding agents that modulate the interaction between LEAP2 and GHSR. Specifically, the present disclosure provides binding agents, such as LEAP2 peptides that bind GHSR and methods of their use to treat, ameliorate, or prevent a neuroendocrine and/or metabolic disease or disorder such as obesity, diabetes, acromegaly, gigantism and/or Prader-Willi syndrome. The present disclosure also provides binding agents, such as antibodies, that bind LEAP2, and methods of their use, to treat, ameliorate, or prevent a neuroendocrine and/or metabolic disease or disorder such as cachexia, anorexia, or other wasting syndromes.

Abstract: Systems, apparatuses, and methods for implementing hypervisor post-write notification of processor state register modifications. A write to a state register of the processor may be detected during guest execution. In response to detecting the write to the state register, the processor may trigger microcode to perform the write and copy the new value of the register to a memory location prior to exiting the guest. The hypervisor may be notified of the update to the state register after it occurs, and the hypervisor may be prevented from modifying the value of the guest's state register. The hypervisor may terminate the guest if the update to the state register is unacceptable. Alternatively, the hypervisor may recommend an alternate value to the guest. If the guest agrees, the guest may set the state register to the alternate value recommended by the hypervisor when the guest resumes operation.

Abstract: A subset of a set of architectural registers in a processing system is marked (or “tainted”) to indicate that speculative use of data in the subset of the architectural registers is constrained based on a taint handling policy. One or more speculation features supported by the processing system are disabled for the instruction so that the one or more speculation features cannot be used on data in the subset. In some cases, values of bits associated with the subset of architectural registers are modified to indicate that the subset is tainted. The taint handling policy can be indicated by values stored in a policy register. Taint markings are tracked in response to values stored in the tainted architectural registers being written to a memory or read from the memory.

Abstract: A state of a first architectural register in a processing system is changed from a first state to a second state that indicates that the first architectural register is to be monitored during speculative execution. A second architectural register in the processing system is associated with a third state in response to the first architectural register being a source register for a memory load instruction that loads data from a memory into the second architectural register during speculative execution. Use of data in the second architectural register is constrained during speculative operations while the second architectural register is in the third state. In some cases, a “set taint” instruction is executed to change the state of the first architectural register from the first state to the second state.

Abstract: Detection apparatus includes a microfluorometer having an objective, an excitation radiation source, and a detector. The detection apparatus also includes a fluidic system for delivering reagents from a reagent cartridge to a flow cell. The fluidic system includes a manifold body having a plurality of fluidic channels configured for fluid communication between the reagent cartridge and the flow cell. The fluidic system also includes a plurality of reagent sippers. The fluidic system also includes a valve configured to mediate fluid between reagent reservoirs and the flow cell. The detection apparatus also includes a flow cell latch clamp module having a clamp cover for holding the flow cell. The objective is configured to direct excitation radiation from the radiation source to the flow cell and to direct emission from the flow cell to the detector. The microfluorometer is movable to acquire wide-field images of different areas of the flow cell.

Abstract: A processing system includes a plurality of input/output (I/O) devices representing a plurality of I/O resources. Each I/O resource has at least one corresponding memory mapped I/O (MMIO) address range. A trap handler detects a write request targeting a configuration space of an identified I/O resource of the plurality of I/O resources and, responsive to determining the identified I/O resource is a protected I/O resource, selectively blocks the write request from further processing by the processing system based on whether the write request would change an MMIO address decoding of the identified I/O resource.

Abstract: The present disclosure provides binding agents that modulate the interaction between LEAP2 and GHSR. Specifically, the present disclosure provides binding agents, such as LEAP2 peptides that bind GHSR and methods of their use to treat, ameliorate, or prevent a neuroendocrine and/or metabolic disease or disorder such as obesity, diabetes, acromegaly, gigantism and/or Prader-Willi syndrome. The present disclosure also provides binding agents, such as antibodies, that bind LEAP2, and methods of their use, to treat, ameliorate, or prevent a neuroendocrine and/or metabolic disease or disorder such as cachexia, anorexia, or other wasting syndromes.