Abstract: A multi-tool (100) includes a power head (120) including a power head housing (122) having a handle (124) operably coupled thereto, a tool attachment (106, 108, 110) configured to perform a work function, the tool attachment (106, 108, 110) being alternately separable from and operably coupled to the power head (120), a motor (140) disposed in the power head housing (122), a battery (130) configured to be operably coupled to the motor (140) to selectively power the motor (140), a drive provider portion (300) disposed at the power head (120), and a drive receiver portion (320) disposed at the tool attachment (106, 108, 110). The drive provider portion (300) includes a driving portion (302) of a shaft (150) operably coupled to the motor (140), and the drive receiver portion (320) includes a driven portion (322) of the shaft (150). The driving portion (302), the drive receiver portion (320), and the motor (140) share a common axis (148).

Abstract: A medical device for measuring blood flow through a blood vessel of a mammal includes a conductive elastomer having a variable resistance. A frame is at least partially surrounding at least a portion of the conductive elastomer, the conductive elastomer is suspended within the frame. A mechanical amplification element is slidably engaged to the conductive elastomer, the mechanical amplification element being configured to slide within the frame and to contact skin of the mammal over the blood vessel when the frame is positioned over the blood vessel, the mechanical amplification element being configured to be displaced when the artery pulsates and changes the resistance of the elastomer.

Abstract: Synergistic queue management techniques are disclosed. The techniques can include receiving, by a server, a first queue action message, the first queue action message indicating a first queue action for a content queue associated with a client device, determining, based on the first queue action, a second queue action for the content queue, the second queue action comprising a supplemental queue action for the first queue action, and sending a second queue action message to the client device, the second queue action message indicating the second queue action.

Abstract: A test adapter assembly for an interface. The test adapter assembly has a test adapter frame having a first pair of opposing sides, a second pair of opposing sides and an engagement mechanism support member, the second pair of opposing sides being shorter than the first pair of opposing side, the first and second pairs of opposing sides forming a test adapter face; and a collar support member, the collar support member having plate portion mounted to one of the second pair of opposing sides of the test adapter frame and a collar mounting portion extending from the plate portion at an angle of 40-50° relative to the face of the test adapter frame.

Abstract: Disclosed are techniques for processing user profiles using data structures that are specialized for processing by a GPU. More particularly, the disclosed techniques relate to systems and methods for evaluating characteristics of user profiles to determine whether to offload certain user profiles to the GPU for processing or to process the user profiles locally by one or more central processing units (CPUs). Processing user profiles may include comparing the interest tags included in the user profiles with logic trees, for example, logic trees representing marketing campaigns, to identify user profiles that match the campaigns.

Abstract: A photoconductive switch that uses materials that support negative differential mobility, whose operation leverages the pulse compression of a charge could to generate the “on” time of the pulse in combination with the speed of light to generate the “off” time of the pulse, is described. In one example, a method of operating a photoconductive switch, which includes two electrodes and a light absorbing material positioned therebetween, includes selecting a value for one or more parameters comprising a voltage for generation of an electric field, a spot size of a laser pulse, a temporal pulse width of the laser pulse, or an intensity of the laser pulse, wherein the selected value(s) for the one or more parameters enable the switch to operate in a region where the light absorbing material exhibits negative differential mobility, and illuminating the light absorbing material with the laser pulse to generate a charge cloud within the light absorbing material.

Abstract: Techniques and systems are used to operate a fully automated vertical greenhouse for low-cost and sustainable production of local produce. The system includes robotic configurations that seed, propagate, transplant, water, and harvest plants, such as leafy greens and herbs, autonomously without direct human intervention. The system may manage and control a process for sprouting seeds, which is the beginning of a plant life cycle and is initiated by first watering. The system may manage and control a process for moving plants from sprouting growing conditions to adult growing conditions, which further include delivery of nutrient rich water to the adult plants. The system may also manage and control a process for gathering and sorting of mature plants (e.g., crops), which may be automatically prepared and sorted for delivery to retail locations.

Abstract: Provided is a firearm cartridge chamber with a relief feature that traps a portion of a cartridge case within the cartridge chamber when fired. The relief feature causes the cartridge case to deform within the chamber, wherein it optionally separates into a forward section and a rearward section. The deformed case remains trapped after firing, preventing extraction of the fired case and the chambering or firing of any subsequent cartridges, thereby causing a firearm malfunction. The cartridge chamber can distinguish between higher and lower pressure cartridges by allowing for normal firing and function with blank training ammunition while also facilitating localized deformation of the cartridge case when firing standard ammunition that includes one or more projectiles. The inventive chamber prevents more than one higher pressure round from firing while allowing lower pressure or training rounds to fire without limitation, which aids in enhanced safety during training exercises.

Abstract: A method for predicting an occurrence of a structural feature in a core image using a backpropagation-enabled process trained by inputting a set of training images of a core image, iteratively computing a prediction of the probability of occurrence of the structural feature for the set of training images and adjusting the parameters in the backpropagation-enabled model until the model is trained. The trained backpropagation-enabled model is used to predict the occurrence of the structural features in non-training core images. The set of training images may include non-structural features and/or simulated data, including augmented images and synthetic images.

Abstract: The present disclosure provides pharmaceutical combinations of orally administered irinotecan and a P-gp inhibitor. The pharmaceutical combinations are suitable for the treatment of cancer in a subject and for reducing or preventing toxicity, hypersensitivity-type infusion reactions, and other negative outcomes resulting from or associated with intravenously administered irinotecan (e.g., Camptosar®) therapy in a subject suffering from cancer.

Abstract: A 3D production apparatus and method that receives a 3D production file containing an extrusion control command for controlling an extruder mechanism. A corrected extrusion control command is generated based on the extrusion control command and a correction formula. The extruder mechanism is controlled in accordance with the corrected extrusion control command.

Abstract: The present disclosure relates to pharmaceutical compositions suitable for inhalation, parenteral administration, and oral administration comprising a an insoluble active ingredient, pharmaceutical systems comprising them, methods of treatment and/or prophylaxis, and uses comprising them.

Abstract: A replacement heart valve prosthesis for transcatheter repair of a native valve, the replacement heart valve comprises a valve construct mounted to the exterior surface of an expandable frame. The frame comprises an expandable region near the distal end of the frame, and a cusp region near the proximal region comprising a plurality of valve attachment features. The valve construct may be attached to the valve construct at least at the valve attachment features. The replacement heart valve prosthesis of present disclosure may be a more durable and long-lasting valve that has added benefits by placing valve tissue between the expandable frame and native cardiac tissue.

Abstract: A laminated window assembly has a first glass pane with a coating formed thereon, a second glass pane, and a polymeric interlayer provided between the first glass pane and the second glass pane. The coating includes a first layer deposited over a major surface of the glass pane, wherein the first layer has a refractive index of 1.6 or more and a thickness of 50 nm or less, a second layer deposited over the first layer, wherein the second layer has a refractive index that is less than the refractive index of the first layer and a thickness of 50 nm or less, a third layer deposited over the second layer, wherein the third layer has a refractive index that is greater than the refractive index of the second layer and a thickness of less than 500 nm, and a fourth layer deposited over the third layer, wherein the fourth layer has a refractive index that is less than the refractive index of the third layer and a thickness of 100 nm or less.

Abstract: A replacement heart valve prosthesis for transcatheter repair of a native valve comprises a frame having a distal end, a proximal end, and a length between the distal end and the proximal end, the frame further comprising an exterior surface and an interior surface defining a lumen, the frame expandable from an unexpanded state to an expanded state. The frame further comprises an expandable region near the distal end of the frame and a cusp region near the proximal end of the frame. The cusp region has a plurality of valve attachment features. A valve construct is mounted to the exterior surface of the frame and attached to the frame at least at the valve attachment features.

Abstract: A replacement heart valve prosthesis for transcatheter repair of a native valve, the replacement heart valve comprises a valve construct mounted to the exterior surface of an expandable frame. The frame comprises an expandable region near the distal end of the frame, and a cusp region near the proximal region comprising a plurality of valve attachment features. The valve construct may be attached to the valve construct at least at the valve attachment features. The replacement heart valve prosthesis of present disclosure may be a more durable and long-lasting valve that has added benefits by placing valve tissue between the expandable frame and native cardiac tissue.

Abstract: The application pertains to methods of treating and/or preventing actinic keratosis, comprising administering a therapeutically effective amount of KX-01, to a subject in need thereof.

Abstract: Disclosed are techniques for processing user profiles using data structures that are specialized for processing by a GPU. More particularly, the disclosed techniques relate to systems and methods for evaluating characteristics of user profiles to determine whether to offload certain user profiles to the GPU for processing or to process the user profiles locally by one or more central processing units (CPUs). Processing user profiles may include comparing the interest tags included in the user profiles with logic trees, for example, logic trees representing marketing campaigns, to identify user profiles that match the campaigns.

Abstract: A method for predicting an occurrence of a geological feature in a geologic core image uses a backpropagation-enabled segmentation process trained by inputting multiple training geologic core images and a set of associated labels of geological features, iteratively computing a prediction of the probability of occurrence of the geological feature for the training images and adjusting the parameters in the backpropagation-enabled segmentation model until the model is trained. The trained backpropagation-enabled segmentation model is used to predict the occurrence of the geological features in non-training geologic core images. Geological features to be predicted with this method include structural features (such as veins, fractures, bedding contacts, etc.), and stratigraphic features (such as lithologic types, sedimentary structures, sedimentary facies, etc.).

Abstract: A bioprocess mixer (1), which comprises: —a support vessel (2) with at least one side wall (3, 4, 5, 6) and a bottom wall (7), where the walls define a support vessel inner volume (8), and at least a first (9) and a second (10) magnetic impeller drive unit; and —a flexible bag (11, 111) adapted to fit inside the support vessel inner volume, where the bag has at least one bag side wall (12, 112, 13, 113, 14, 15), a bag bottom wall (16, 116) and a bag top wall (17, 117) defining a bag inner volume (18), and at least a first (19) and a second (20) magnetic impeller rotatably attached to a bag wall in the bag inner volume.