Abstract: The present invention provides, in part, compounds of Formula I: and pharmaceutically acceptable salts thereof; processes for the preparation of; intermediates used in the preparation of; and compositions containing such compounds or salts, and their uses for treating D1-mediated (or D1-associated) disorders including, e.g., schizophrenia (e.g., its cognitive and negative symptoms), cognitive impairment (e.g.

Abstract: The present disclosure provides pharmaceutical combinations of orally administered docetaxel and a P-gp inhibitor. The pharmaceutical combinations are suitable for the treatment of cancer in a subject and for reducing or preventing toxicity, hypersensitivity-type infusion reactions, and other negative outcomes resulting from or associated with intravenously administered docetaxel (e.g., Taxotere® or docetaxel formulated with polysorbate 80) therapy in a subject suffering from cancer.

Abstract: In one aspect, a playback device is configured to (i) receive a first stream of audio data representing audio content from a computing system, (ii) detect an indication that a source of the audio content is to switch from the computing system to a user device; (iii) after detecting the indication, establish a point-to-point wireless link with the user device over which to receive a second stream of audio data; (iv) receive the second stream of audio data representing the audio content; (v) determine a future time at which to transition from playing back the audio content using the first stream of audio data to playing back the audio content using the second stream of audio data; and (vi) at the future time, transition from playing back the audio content using the first stream of audio data to playing back the audio content using the second stream of audio data.

Abstract: Engine combustion phasing control techniques utilize a trained feedforward artificial neural network (ANN) to model both base and maximum brake torque (MBT) spark timing based on six inputs: intake and exhaust camshaft positions, mass and temperature of an air charge being provided to each cylinder of the engine, engine speed, engine coolant temperature. The selected target spark timing could be adjusted based on a two-dimensional surface having engine speed and air charge mass as inputs. The target spark timing adjustment could be performed only during an initial period when the trained ANN is immature. The ANN could also be trained using dynamometer data for the engine that is artificially weighted for high load regions where accuracy of spark timing is critical.

Abstract: A Rogowski coil in a sensor unit has voltage induced by a conductor surrounded by the Rogowski coil. The voltage is integrated to represent current which is converted to digital data representing current in the conductor and sent wirelessly to a multimeter. The sensor unit may receive control signals from the multimeter and a remote control apparatus. A plurality of sensor units may be networked and controlled by the remote control apparatus.

Abstract: A method and apparatus for forming torsional magnetic reconnection, and converting stored magnetic energy into charged particle kinetic energy and particle acceleration, is claimed. A torsional magnetic reconnection apparatus generally comprises (1) a vacuum environment housing (2) a plurality of conducting coils to form a magnetic field fan-spine topology and (3) a plasma generation device providing an azimuthal magnetic field perturbation such that current sheets are formed and magnetic reconnection processes can occur. Electric current energization of the plurality of conducting coils generates a potential magnetic fan-spine topology. A simultaneous capacitor bank discharge forms and axially drives a plasma sheath, featuring an azimuthal magnetic field, toward the fan-spine magnetic null that forces the diffusion of magnetic flux through the plasma. This magnetic to plasma kinetic energy conversion process accelerates charged particles far away from the reconnection region along open magnetic field lines.

Abstract: Techniques for controlling a forced-induction engine having a low pressure cooled exhaust gas recirculation (LPCEGR) system comprise determining a target boost device inlet pressure for each of one or more systems that could require a boost device inlet pressure change as part of their operation and boost device inlet pressure hardware limits for a set of components in the induction system, determining a final target boost device inlet pressure based on the determined sets of target boost device inlet pressures and boost device inlet pressure hardware limits, and controlling a differential pressure (dP) valve based on the final target boost device inlet pressure to balance (i) competing boost device inlet pressure targets of the one or more systems and (ii) the set of boost device inlet pressure hardware limits in order to optimize engine performance and prevent component damage.

Abstract: Certain example embodiments relate to electric, potentially-driven shades usable with insulating glass (IG) units, IG units including such shades, and/or associated methods. In such a unit, a dynamic shade is located between the substrates defining the IG unit, and is movable between retracted and extended positions. The dynamic shade includes on-glass layers including a transparent conductor and an insulator or dielectric film, as well as a shutter. The shutter includes a resilient polymer-based layer and a conductive layer. A first voltage is applied to the transparent conductors to cause the shutter to extend to a closed position, and a second voltage is applied to a stop to electrostatically hold the shutter in the closed position. The first and second voltage levels can be reduced once the shutter is extended to the closed position, the reduction to the first voltage level being greater than the reduction to the second voltage level.

Abstract: Embodiments of a method of printing low volumes of paper bags on a digital printing press are provided. In the method, a plurality of orders are received. Each order includes a particular format relating to a bag size selected from a predetermined number of bag sizes and a graphic to be printed. In the method, the plurality of orders are organized into a plurality of batches. Each batch includes orders of the plurality of orders having a same bag size. A first batch is selected, and the graphic of the orders contained in the first batch is digitally printed on a first roll of paper having dimensions associated with the bag size of the first batch. The first roll of paper is fed through the digital printing press, and the digital printing press prints the graphic of each order contained in the first batch without stopping when transitioning between orders.

Abstract: A method and apparatus for forming torsional magnetic reconnection, and converting stored magnetic energy into charged particle kinetic energy and particle acceleration, is claimed. A torsional magnetic reconnection apparatus generally comprises (1) a vacuum environment housing (2) a plurality of conducting coils to form a magnetic field fan-spine topology and (3) a plasma generation device providing an azimuthal magnetic field perturbation such that current sheets are formed and magnetic reconnection processes can occur. Electric current energization of the plurality of conducting coils generates a potential magnetic fan-spine topology. A simultaneous capacitor bank discharge forms and axially drives a plasma sheath, featuring an azimuthal magnetic field, toward the fan-spine magnetic null that forces the diffusion of magnetic flux through the plasma. This magnetic to plasma kinetic energy conversion process accelerates charged particles far away from the reconnection region along open magnetic field lines.

Abstract: The present invention provides, in part, compounds of Formula I: and pharmaceutically acceptable salts thereof; processes for the preparation of; intermediates used in the preparation of; and compositions containing such compounds or salts, and their uses for treating D1-mediated (or D1-associated) disorders including, e.g., schizophrenia (e.g., its cognitive and negative symptoms), cognitive impairment (e.g., cognitive impairment associated with schizophrenia, AD, PD, or pharmacotherapy therapy), Parkinson's disease and chronic apathy.

Abstract: Disclosed are techniques for processing user profiles using data structures that are specialized for processing by a GPU. More particularly, the disclosed techniques relate to systems and methods for evaluating characteristics of user profiles to determine whether to offload certain user profiles to the GPU for processing or to process the user profiles locally by one or more central processing units (CPUs). Processing user profiles may include comparing the interest tags included in the user profiles with logic trees, for example, logic trees representing marketing campaigns, to identify user profiles that match the campaigns.

Abstract: Disclosed are techniques for processing user profiles using data structures that are specialized for processing by a GPU. More particularly, the disclosed techniques relate to systems and methods for evaluating characteristics of user profiles to determine whether to offload certain user profiles to the GPU for processing or to process the user profiles locally by one or more central processing units (CPUs). Processing user profiles may include comparing the interest tags included in the user profiles with logic trees, for example, logic trees representing marketing campaigns, to identify user profiles that match the campaigns.

Abstract: Disclosed are techniques for processing user profiles using data structures that are specialized for processing by a GPU. More particularly, the disclosed techniques relate to systems and methods for evaluating characteristics of user profiles to determine whether to offload certain user profiles to the GPU for processing or to process the user profiles locally by one or more central processing units (CPUs). Processing user profiles may include comparing the interest tags included in the user profiles with logic trees, for example, logic trees representing marketing campaigns, to identify user profiles that match the campaigns.

Abstract: Oral treatment devices formed from wax-based compositions that are thermally stable when formed into a three-dimensional shape to a temperature of at least 45° C. and plastically deformable at room temperature (25° C.). The wax-based compositions include a wax fraction homogeneously blended with a polymer fraction. The wax fraction includes at least one wax. The polymer fraction includes at least one polymer selected such that, when the wax and polymer are homogeneously blended together, they yield a wax-based composition having the desired properties of thermal stability and plastic deformability. Oral treatment devices are dimensionally stable to a temperature of at least 40° C. without external support and can be plastically deformed in a user's mouth to become at least partially customized to the size and shape of user's unique dentition and/or an appliance in a user's mouth.

Abstract: A support apparatus configured to support a person is provided. The support apparatus includes a top surface including one or more predetermined areas, one or more conduits located inside the support apparatus which are located proximate to the one or more predetermined areas, and an air supply configured to provide air to the one or more conduits for delivering to the one or more predetermined areas. The air supply includes a temperature sensor configured to measure a temperature of the air provided by the air supply, a cooling element, and a controller communicatively coupled to the temperature sensor and the cooling element. The controller determines whether the measured temperature of the air is higher than a predetermined temperature, and controls the cooling element to cool the air to the predetermined temperature if it is determined that the temperature of the air is higher than the predetermined temperature.

Abstract: An exemplary mobile apparatus for assessing an operating condition of an asset. The mobile device includes at least one sensor device for acquiring data related to one or more operational or environmental characteristics of an asset during operation. The mobile device further includes a processing device encoded with a neural network architecture having one or more models trained to identify one or more operating conditions of one or more assets according to asset type. The processing device can determine an operating condition of the asset by extracting features from the acquired data and comparing attributes of the extracted features to attributes of at least one known operating condition determined through training of the models. The mobile device can also include an output interface to output a result of the determination performed by the processing device, which can include communicating the result to a remote device.

Abstract: A solar panel system is assembled into a three-dimensional volume with the solar cell(s) positioned on an inward facing surface to collect sunlight and reflect sunlight from different angles as the sun passes overhead. Embodiments may be mounted into the interior of a building with a top end of the module being positioned on or proximate a roof surface and disposed to collect sunlight into the module interior below the roof line. Some embodiments may be pyramidal shaped. Outdoor mounting of the solar panel module includes embodiments that may be held in a frame and rail mounted system.

Abstract: A rotorcraft has a fuselage, an engine disposed substantially laterally centrally relative to the fuselage, and an air intake system (AIS). The AIS has a first duct configured to provide streamline air flow, a second duct configured to provide streamline air flow, and a combining section configured to receive streamline air flow from each of the first duct and the second duct. The combining section is further configured to output streamline air flow.