Abstract: A modified adenovirus, in particular Enadenotucirev (EnAd), armed with at least two bispecific T cell engagers each comprising at least two binding domains, wherein at least one of the domains is specific for a surface antigen on an immune cell of interest, such as a T-cell of interest. Also provided are a composition, such as a pharmaceutical formulation comprising the virus, use of the virus and virus formulations for treatment, such as in the treatment of cancer. The disclosure also extends to processes for preparing the virus.

Abstract: The disclosure describes equipment for magnetic annealing of a substrate, the equipment including: an anneal chamber configured to heat and cool a substrate held at a soak location along a first direction in the anneal chamber, the anneal chamber including: a heater, a cooler, and a substrate lifter including a substrate holder, where the substrate holder is configured to support a substrate oriented such that the first direction is perpendicular to a major surface of the substrate; and a magnet assembly configured to establish a homogeneous zone in the anneal chamber, the soak location being within the homogeneous zone, the homogeneous zone including a region of magnetic field.

Abstract: In an embodiment, an apparatus includes a first baseband section to receive a calibration signal; a first radio frequency (RF) section configured to generate a RF calibration signal based on modulating the calibration signal. The calibration signal comprises an orthogonal code based signal. The apparatus includes a second RF section to receive the RF calibration signal and generate a received calibration signal based on demodulating the RF calibration signal; a calibration section; a first antenna electrically coupled to the first RF section and configured to transmit the RF calibration signal; and a second antenna electrically coupled to the second RF section and configured to receive the RF calibration signal. The calibration section is configured to determine one or more of gain, baseband delay, or RF delay to calibrate the first RF section; and the second antenna is switchable between receiving the RF calibration signal and transmitting an encoded data signal.

Abstract: The present disclosure relates generally to systems and methods for generating, processing and correlating data from multiple sensors in an autonomous navigation system, and more particularly to the utilization of configurable and dynamic sensor modules within light detection and ranging systems that enable an improved correlation between sensor data as well as configurability and responsiveness of the system to its surrounding environment.

Abstract: A modified adenovirus, in particular Enadenotucirev (EnAd), armed with a bispecific T cell activator comprising at least two binding domains, wherein at least one of the domains is specific for a surface antigen on a T-cell of interest. Also provided are a composition, such as a pharmaceutical formulation comprising the virus, use of the virus and virus formulations for treatment, such as in the treatment of cancer. The disclosure also extends to processes for preparing the virus.

Abstract: The present invention relates to a polymer for a non-aqueous electrolyte rechargeable battery, an electrode slurry for a rechargeable battery and a rechargeable battery comprising the same.

Abstract: A handheld electronic device, such as a GPS-enabled wireless communications device with an embedded camera, a GPS-enabled camera-phone or a GPS-enabled digital camera, determines whether ephemeris data needs to be obtained for geotagging digital photos taken with the device. By monitoring user activity with respect to the camera, such as activation of the camera, the device can begin pre-acquisition of a GPS position fix by obtaining needed ephemeris data before the photograph is actually taken. This GPS pre-acquisition improves the likelihood that a position fix (GPS lock) is achieved by the time the photo is taken (to enable immediate geotagging). Alternatively, the photo can be geotagged retroactively by appending the current location to the metadata tag associated with the digital photo. An optional acquisition status indicator can be displayed on a user interface of the device to indicate that a position fix is being obtained.

Abstract: A handheld electronic device, such as a GPS-enabled wireless communications device with an embedded camera, a GPS-enabled camera-phone or a GPS-enabled digital camera, determines whether ephemeris data needs to be obtained for geotagging digital photos taken with the device. By monitoring user activity with respect to the camera, such as activation of the camera, the device can begin pre-acquisition of a GPS position fix by obtaining needed ephemeris data before the photograph is actually taken. This GPS pre-acquisition improves the likelihood that a position fix (GPS lock) is achieved by the time the photo is taken (to enable immediate geotagging). Alternatively, the photo can be geotagged retroactively by appending the current location to the metadata tag associated with the digital photo. An optional acquisition status indicator can be displayed on a user interface of the device to indicate that a position fix is being obtained.

Abstract: A handheld electronic device, such as a GPS-enabled wireless communications device with an embedded camera, a GPS-enabled camera-phone or a GPS-enabled digital camera, determines whether ephemeris data needs to be obtained for geotagging digital photos taken with the device. By monitoring user activity with respect to the camera, such as activation of the camera, the device can begin pre-acquisition of a GPS position fix by obtaining needed ephemeris data before the photograph is actually taken. This GPS pre-acquisition improves the likelihood that a position fix (GPS lock) is achieved by the time the photo is taken (to enable immediate geotagging). Alternatively, the photo can be geotagged retroactively by appending the current location to the metadata tag associated with the digital photo. An optional acquisition status indicator can be displayed on a user interface of the device to indicate that a position fix is being obtained.

Abstract: A method is provided in which multiple layers are formed. Each of the layers includes at least a first set of ceramic fibers and a second set of ceramic fibers. The first set is arranged at an angle with respect to the second set. The first set and the second set define a plurality of pores therebetween. The layers are arranged on top of each other to form a porous preform. The pores of the layers arranged on top of each other are aligned. The pores define a plurality of channels extending continuously through the porous preform from a first side of the porous preform to a second side of the porous preform. Each channel comprises one inlet at the first side of the porous preform and one outlet at the second side of the porous preform. The porous preform is infiltrated with a matrix material.

Abstract: A shelving unit can include a reverse cantilevered bracket assembly. The bracket assembly can be configured to facilitate a modular design that permits height adjustment of shelves for an article of furniture. In some embodiments, the brackets can be configured to be positioned to avoid obstructing a front opening so that a user can easily access shelfs supported by the brackets. In some embodiments, the brackets can be positioned to minimize their appearance to improve the aesthetic effect of the shelving unit.

Abstract: A method of fabricating a semiconductor device is provided, which includes providing a plurality of fins over a substrate and forming a plurality of first gate structures having a first gate pitch and a plurality of second gate structures having a second gate pitch traversing across a first and a second set of fins, respectively. The second gate pitch is wider than the first gate pitch. Epitaxial regions are formed between adjacent second gate structures in the second set of fins. A dielectric layer is deposited over the second gate structures and the epitaxial regions. Contact openings are formed in the dielectric layer. At least one of the contact openings is formed over the second gate structure where the second gate structure traverses across the second set of fins. The contact openings are filled with a conductive material to form contact structures electrically coupled to the second gate structures.

Abstract: Methods and devices are provided relating to taking an action in response to determining that a person who is present in the vicinity of the device, such as a smart speaker, is not authorized to be present. In an aspect, the electronic device receives the notification and a topic identifier associated with the notification. Information identifying persons located in the vicinity of the electronic device may be received. The device may then receive and/or determine information identifying at least one person located within the vicinity who is not authorized, based on the topic identifier, to be present in the vicinity when the notification is to be outputted. The device generates an output signal indicating receipt of the notification and that there is at least one person present in the vicinity who is not authorized to be present when the notification is to be outputted.

Abstract: A disclosed wireless tunneling system tunnels communications between two processing apparatuses through a wireless link, while maintaining compliance of the communications between the two processing apparatuses with a wired communication protocol. In one embodiment, the wireless tunneling system includes two wireless tunneling apparatuses that communicate with each other through the wireless link. A local wireless tunneling apparatus is coupled to a local processing apparatus through a wired connection and a remote wireless tunneling apparatus is coupled to the remote processing apparatus through another wired connection. In one aspect, the local wireless tunneling apparatus predicts a state of the remote processing apparatus, and mirrors the predicted state of the remote processing apparatus.

Abstract: A disclosed wireless tunneling system tunnels communications between two processing apparatuses through a wireless link, while maintaining compliance of the communications between the two processing apparatuses with a wired communication protocol. In one embodiment, the wireless tunneling system includes two wireless tunneling apparatuses that communicate with each other through the wireless link. A local wireless tunneling apparatus is coupled to a local processing apparatus through a wired connection and a remote wireless tunneling apparatus is coupled to the remote processing apparatus through another wired connection. In one aspect, the local wireless tunneling apparatus predicts a state of the remote processing apparatus, and mirrors the predicted state of the remote processing apparatus.

Abstract: Disclosed is an electrical connector having a substrate and movable electrical contacts which are mounted to the substrate and extend a distance D from the substrate. A layer of compressible material (such as a foam or elastomeric material) is positioned on the substrate adjacent at least some of the electrical contacts and ideally has an uncompressed thickness slightly greater than the distance D to provide for protection of the electrical contacts. When a mating electrical device such as an electrical connector or other circuit member is mated to the electrical connector with its electrical contacts and its layer of compressible material, the layer of compressible material is compressed to a thickness less than the distance D, allowing the contacts to make a suitable electrical interconnection to the mating electrical device.

Abstract: A disclosed wireless tunneling system tunnels communications between two processing apparatuses through a wireless link, while maintaining compliance of the communications between the two processing apparatuses with a wired communication protocol. In one embodiment, the wireless tunneling system includes two wireless tunneling apparatuses that communicate with each other through the wireless link. A local wireless tunneling apparatus is coupled to a local processing apparatus through a wired connection and a remote wireless tunneling apparatus is coupled to the remote processing apparatus through another wired connection. In one aspect, the local wireless tunneling apparatus predicts a state of the remote processing apparatus, and mirrors the predicted state of the remote processing apparatus.

Abstract: An image is saved to a contact record or set as a home screen directly from a camera application of a portable electronic device. The method includes: capturing an image using a camera that is integrated into the portable electronic device, selecting at least a portion of the image, selecting a contact record from an address book application or selecting a set as home screen option.