Abstract: Implementations include methods of controlling a haptic response comprising receiving a force signal from a force sensor; determining a force magnitude associated with the force signal; comparing the force magnitude with an initial threshold force amount to determine whether the force magnitude exceeds the initial threshold force amount; measuring an elapsed time that the force magnitude exceeds the initial threshold force amount; comparing the elapsed time to a minimum elapsed time; if the elapsed time being greater than the minimum elapsed time, generating a haptic feedback control signal, the haptic feedback control signal causing a haptic actuator to propagate a plurality of pressure waves at a propagation frequency, the propagation frequency being proportional to the force magnitude; and generating a scroll control signal that causes a menu system to scroll through a plurality of menu options provided by the menu system at a scroll frequency associated with the propagation frequency.

Abstract: The disclosure is directed to an Echo-Planar-Imaging (EPI) magnetic resonance imaging techniques combined with a variable-density undersampling scheme. The technique comprises generating an RF pulse, applying a switched frequency-encoding read out gradient in a variable time interval, and applying simultaneously an intermittently blipped low-magnitude phase-encoding gradient with a variable value of an integral of the phase-encoding gradient. The aforementioned steps are carried out such that the k-space is at least partially undersampled and the time interval of one read out gradient is varied depending on the integral of the phase encoding gradient, such that a ratio between the variable time interval of the read out gradient and the integral of the corresponding phase encoding gradient is kept above or at a predetermined constant value, which is related to a predetermined criteria of image quality.

Abstract: Compounds of Formula (I): pharmaceutically acceptable salts thereof, deuterated derivatives of any of the foregoing, and metabolites of any of the foregoing are disclosed. Pharmaceutical compositions comprising the same, methods of treating cystic fibrosis using the same, and methods for making the same are also disclosed. Also disclosed are solid state forms of Compound 1 and salts and solvates thereof.

Abstract: A heating, ventilation, and/or air conditioning (HVAC) system includes a vessel configured to receive refrigerant from a condenser of the HVAC system, an evaporator configured to receive the refrigerant from the vessel, a first conduit configured to direct a first flow of the refrigerant to a first inlet of the evaporator, and a second conduit configured to direct a second flow of the refrigerant to a second inlet of the evaporator. The second inlet is above the first inlet relative to a vertical axis.

Abstract: The present teaching relates to medical suggestion searching. In one example, data related to a medication drug are obtained. One or more candidate prescription strings are identified from the obtained data. Each of the candidate prescription strings is associated with a plurality of attributes. Each of the one or more candidate prescription strings is automatically processed based on at least one model to generate one or more prescription strings each with an associated ranking. At least some of the generated one or more prescription strings and the associated rankings are stored for future use.

Abstract: A propulsion system is provided, wherein the propulsion system includes an afterburner assembly. The afterburner assembly including: an exhaust section and a fuel injector assembly that is operable to inject fuel in the exhaust section. The fuel injector assembly includes a plurality of fuel injection members. The plurality of fuel injection members defines a hot zone and a cold zone. The cold zone is positioned to provide a noise insulation barrier for the hot zone.

Abstract: Methods, systems, and devices for performance monitoring for a memory system are described. A memory system may use a set of counters to determine state information for the memory system. The memory system may also use a set of timers to determine latency information for the memory system. In response to a request for performance information, the memory system may transmit state information, latency information, or both to a host system.

Abstract: The invention relates to a method for producing embedded hydrogel contact lenses each having an insert that comprises alignment features capable of capable of aligning the insert in depth and radial position in a female mold half during cast molding of an embedded hydrogel contact lens. The alignment features protrude from the front surface, are rotationally symmetric with respect to the central axis of the insert and independently have a shape having a curvature being greater than 2 folds of the curvature of the molding surface so as to minimize contacting area between the alignment features and the molding surface. The use of such an insert can simplify the process for producing embedded hydrogel contact lenses and enable the process to be implemented readily in an automatic production.

Abstract: Various embodiments provide for one or more processor instructions and memory instructions that enable a memory sub-system to copy, move, or swap data across (e.g., between) different memory tiers of the memory sub-system, where each of the memory tiers is associated with different memory locations (e.g., different physical memory locations) on one or more memory devices of the memory sub-system.

Abstract: Described apparatuses and methods balance memory-portion accessing. Some memory architectures are designed to accelerate memory accesses using schemes that may be at least partially dependent on memory access requests being distributed roughly equally across multiple memory portions of a memory. Examples of such memory portions include cache sets of cache memories and memory banks of multibank memories. Some code, however, may execute in a manner that concentrates memory accesses in a subset of the total memory portions, which can reduce memory responsiveness in these memory types. To account for such behaviors, described techniques can shuffle memory addresses based on a shuffle map to produce shuffled memory addresses. The shuffle map can be determined based on a count of the occurrences of a reference bit value at bit positions of the memory addresses. Using the shuffled memory address for memory requests can substantially balance the accesses across the memory portions.

Abstract: Compounds, compositions and methods are provided for modulating the activity of EP2 and EP4 receptors, and for the treatment, prevention and amelioration of one or more symptoms of diseases or disorders related to the activity of EP2 and EP4 receptors. In certain embodiments, the compounds are antagonists of both the EP2 and EP4 receptors.

Abstract: A system for handling yarn packages and empty cores. The system includes a winder, a creel and a gripper assembly. The winder is configured to receive an empty core and to wind a predetermined length of yarn onto the empty core to create a yarn package. The creel is configured to provide an array of creel positions for receiving a yarn package. The gripper assembly is configured to be moveable between the winder and the creel. The gripper assembly has a jaw adapted to grip a yarn package when delivering the yarn package from the winder to the creel and to grip an empty core when removing the empty core from the creel and delivering the empty core to the winder. Devices, systems and methods for controlling a yarn tail, loading a yarn spool into a creel, and feeding the yarn through the creel, are also disclosed.

Abstract: A haircare appliance has an air inlet, an air outlet, and an airflow generator for generating an airflow from the air inlet to the air outlet. The air outlet has a first aperture having a first cross-sectional area, and a second aperture having a second cross-sectional area greater than the first cross-sectional area. The haircare appliance has a first configuration in which airflow through the second aperture is inhibited, and a second configuration in which airflow through the second aperture is uninhibited.

Abstract: Systems and methods are provided for data synchronization for client application generated data. Content may be generated by a client application executed by a creator client device and sent to a server system that may distribute the content to one or more additional client devices of recipients of the content. The server system can push content to the recipient client devices without receiving a request for the content from the recipient client devices. The content generated by the creator client device may be stored by each of the creator client device, by the server system, and by the one or more recipient client devices. The server system may also generate version data related to respective versions of content that may be consumed by a client application. The version data may be used by client devices to determine versions of content that may be missing from the client devices.

Abstract: Disclosed is a substance which down-regulates the activity of a MAST gene, or the activity of a transcription or translation product of a MAST gene, for use in the prevent and/or treatment of an inflammatory skin condition in a mammalian subject.

Abstract: The subject matter of the present disclosure generally relates to techniques for neuromodulation of a tissue that include applying energy (e.g., ultrasound energy) into the tissue at multiple regions of interest, concurrently or consecutively. The neuromodulation may result in tissue displacement, which may be observed through changes in one or more molecules of interest.

Abstract: Method and systems for preparing and analyzing a DNA sample from a subject are provided herein. Also provided are methods and systems for obtaining, analyzing, and manipulating genomic and proteomic sequence data. In particular, methods and systems provided herein involve transformation of raw genetic or proteomic sequence into a compressed data set and transmission of the compressed data set using a fixed binary encoding scheme capable of compressing the data by up to 75%. An interface is in communication with the compression module and configured to display transmitted genomic and proteomic sequence data.

Abstract: The disclosed embodiments include a protective housing for a fragile article for containing fluid medicament.

Abstract: The invention provides a compound of Formula (I) or a pharmaceutically acceptable salt of the compound, wherein R1, R2, R3, Z, A1, L and A2 are as described herein; pharmaceutical compositions thereof; and the use thereof in treating diseases, conditions or disorders modulated by the inhibition of an acetyl-CoA carboxylase enzyme(s) in an animal.

Abstract: A new and distinct variety of blueberry plant, which is denominated varietally as ‘NS 16-6’ is described, with a very dense fruit cluster density, medium to long leaf length, large to very large fruit size, medium firm fruit, fruiting on one-year-old shoots only, medium plant vigor, and low to medium fruit acidity under the ecological conditions prevailing in Yanchep, Western Australia.