Abstract: A system and method are provided for quantifying greenhouse gas (GHG) emissions associated with vehicle traffic. The method includes receiving data from a plurality of devices located at a plurality of traffic intersections in a traffic network, each device comprising at least one sensor configured to obtain data from the corresponding traffic intersection; using the received data and a traffic model to determine vehicle trajectory data; using the vehicle trajectory data and an emissions model to obtain corresponding GHG emissions data; and evaluating the corresponding GHG emissions data to a baseline of GHG emissions using a GHG quantification methodology to determine a GHG reduction that can achieve a carbon offset credit.

Abstract: This invention relates to methods of treating or preventing viral infections caused by flaviviruses, such as dengue virus, yellow fever virus, West Nile virus or Japanese encephalitis virus or infections caused by Chikungunya virus (CHIKV). The methods involve the administration of retinoic acid analogues to subjects who have, are suspected of having a flavivirus infection or infection with CHIKV, or to those who are at risk of becoming infected with a flavivirus or becoming infected with CHIKV.

Abstract: Systems, apparatuses, and methods for predictive memory access are described. Memory control circuitry instructs a memory array to read a data block from or write the data block to a location targeted by a memory access request, determines memory access information including a data value correlation parameter determined based on data bits used to indicate a raw data value in the data block and/or an inter-demand delay correlation parameter determined based on a demand time of the memory access request, predicts that read access to another location in the memory array will subsequently be demanded by another memory access request based on the data value correlation parameter and/or the inter-demand delay correlation parameter, and instructs the memory array to output another data block stored at the other location to a different memory level that provides faster data access speed before the other memory access request is received.

Abstract: A liquid dispersion made by a process is disclosed. The process includes forming multicellular networks having a diameter of 1,000 ?m or smaller by at a temperature of 1100° C. or less, in the presence of a powder of template particles, forming carbon shells, each of the carbon shells generally encapsulating a template particle and together with the encapsulated template particle comprising a heterostructure. The heterostructure comprises a particle diameter of 1,000 ?m or smaller and a morphology of interconnected structural subunits and, between the structural subunits, exohedral pores.

Abstract: A contact sensor for the repeatable detection of small, high frequency mechanical vibrations in external systems is presented herein. The sensor includes a metal housing with an attachment device at one end and an output at the other end. Inside the metal housing is a core assembly that includes a piezo transducer assembly suspended or isolated between an actuator and a biasing device. The actuator may be in the form of a ceramic sphere that sits at least partially within a recess on the inside of the housing and is in physical contact with the piezo transducer assembly. The biasing device may be in the form of a spring that causes the piezo transducer assembly to be pressed against the actuator at a contestant and known amount of tension.

Abstract: A method of using a medical tool comprising a cranial access drill includes placing a guide-hub against a cranial drilling surface, guiding a drill bit into the guide-hub along an axial direction of the guide-hub, drilling the cranial drilling surface in the axial direction with the drill bit using a motor, detecting, using a controller, an electrical parametric change at the drill bit that corresponds to puncturing the cranial drilling surface, and deactivating, using the controller, the motor in response to detecting the electrical parametric change.

Abstract: Solid forms including 7-[[(1S)-1-[4-[(1S)-2-cyclopropyl-1-(4-prop-2-enoylpiperazin-1-yl)ethyl]phenyl]ethyl]amino]-1-ethyl-4H-pyrimido[4,5-d][1,3]oxazin-2-one and a dihydroxybenzoic acid selected from 2,5-dihydroxybenzoic acid, 2,4-dihydroxybenzoic acid, and 2,3-dihydroxybenzoic acid are provided, as well as pharmaceutical compositions including the solid forms, methods for using the solid forms in treating cancer patients, and methods of making the solid forms.

Abstract: Disclosed are compounds of Formula 1, including all stereoisomers, N-oxides, and salts thereof: wherein R1, R2, R3, R4, R5, R6, Q1, Q2, Y1, and Y2 are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling undesired vegetation comprising contacting the undesired vegetation or its environment with an effective amount of a compound or a composition of the invention.

Abstract: A method of delivering a prosthetic valve to a native mitral valve of patient's heart may include providing a radially expandable prosthetic mitral valve which has an upstream atrial portion, a downstream ventricular portion and an annular region therebetween. A constraint is removed from the ventricular portion thereby allowing radial expansion of a ventricular portion. A first anchoring tab on the ventricular portion is radially expanded and an annular region is radially expanded. An atrial skirt on the atrial flange is radially expanded after radial expansion of the ventricular portion.

Abstract: A new and distinct variety of blueberry plant, which is denominated varietally as ‘NS 16-6’ is described, with a very dense fruit cluster density, medium to long leaf length, large to very large fruit size, medium firm fruit, fruiting on one-year-old shoots only, medium plant vigor, and low to medium fruit acidity under the ecological conditions prevailing in Yanchep, Western Australia.

Abstract: Variants of Squalene Hopene Cyclase (SHC) isolated from Gluconobacter morbifer are provided as is a method for using the variant G. morbifer SHC to biocatalytically convert homofarnesol to ambrox.

Abstract: Systems, methods, and non-transitory computer-readable media can determine contextual information associated with an environment including a vehicle and at least one agent for generating a computer simulation based on the environment. One or more behavior constraints for the at least one agent can be determined based on the contextual information. A set of trajectories can be generated based on the one or more behavior constraints. A trajectory can be selected from the set of trajectories based on determining that the trajectory satisfies one or more predetermined criteria. The computer simulation can be generated, wherein the computer simulation includes monitoring driving behavior of the vehicle in response to the vehicle interacting with the at least one agent based on the selected trajectory.

Abstract: A Business Method Invention to transact an Independent Inventor's Intangible Assets into Industry of Inventor's native Nation. A Process means to convey license usage to top-most Governmental and Industry leadership agencies and corporations, providing the formation, booking or floating of Treasury Assets, a cash-equivalent ledger item on the Asset-Side of the Balance Sheet. Also, a net-equal tangible value Swap of the pro-se Independent Inventor's IRS-governed Fair Market Value amortization deduction, said Swap to USA Federal or other major municipality, providing Government a tool for Demand-Side economic stimulus, over a fifteen-year period, by distributing Its swap value as per capita US taxpayer or citizen or business tax relief, or synthetic pay raise, or to targeted needs situations. A business method configuring a central bank or Treasury balance asset based upon the financial value of a nation's expired Intangible Assets.

Abstract: The embodiments of present invention provide processes and an intermediate for the large-scale preparation of 2,4,6-trifluoro-N-[6-(1-methylpiperidine-4-carbonyl)-2-pyridyl]benzamide hemisuccinate, and formulations and product forms made by these processes. The embodiments of the present invention further provide for the preparation of lasmiditan acetate, 2,4,6-trifluoro-N-[6-(1-methylpiperidine-4-carbonyl)-2-pyridyl]benzamide acetate salt, and/or pharmaceutical compositions thereof, and/or uses of lasmiditan acetate and formulations thereof in subcutaneous drug delivery.

Abstract: In an embodiment, the present invention provides a compound of the formula: or a pharmaceutically acceptable salt thereof, and methods of using this compound for treating type II diabetes mellitus.

Abstract: An aviation connectivity gateway module for remote access to an aircraft's systems and remotely offloading its aircraft data. The module broadly comprises a CPU, a first set of communication elements, a second set of communication elements, a memory, a battery, an IMU, a GPS module, and a number of antennas. The module responds to remote prompts and offloads aircraft data when the aircraft is powered off. An aviation connectivity gateway module for complete BVLOS cellular network connectivity broadly comprises a CPU, a set of electronic connectors, a memory, an IMU, a GPS module, a first cellular connectivity element, a second cellular connectivity element, and a number of antennas. The module switches between the first cellular communication element and the second communication element based a status of the aircraft.

Abstract: The embodiments of present invention provide processes and an intermediate for the large-scale preparation of 2,4,6-trifluoro-N-[6-(1-methylpiperidine-4-carbonyl)-2-pyridyl]benzamide hemisuccinate, and formulations and product forms made by these processes. The embodiments of the present invention further provide for the preparation of lasmiditan acetate, 2,4,6-trifluoro-N-[6-(1-methylpiperidine-4-carbonyl)-2-pyridyl]benzamide acetate salt, and/or pharmaceutical compositions thereof, and/or uses of lasmiditan acetate and formulations thereof in subcutaneous drug delivery.

Abstract: Method and apparatus for navigating along a vessel network of a body. An imaging catheter has an elongated body with opposing ends and a central lumen extending therethrough. A plurality of forward-facing imaging sensors are disposed at at least a first end, and a push wire is affixed to the second end. The central lumen is sized to allow passage of a deployable structure, such as a stent or an inflatable balloon, through the imaging catheter along a guide wire to a target location. The imaging catheter is configured for advancement and retraction to successively image the target location, the structure in the undeployed state, and the structure in the deployed state. Intravascular ultrasound (IVUS) or other types of image data can be captured. An external imaging system can additionally be used to provide top-down, 2D and/or 3D imaging of the catheter and structure at the target location.

Abstract: A device adapted for attachment to a coupler of a trailing railcar of a train includes an enclosure defining an internal compartment, a port adapted for connection to an air brake hose receiving air from a brake pipe of the train, a handle extending from the enclosure, a communication device disposed within the internal compartment of the enclosure, and at least one antenna connected to the communication device and extending at least partially through the internal compartment of the enclosure and into an internal cavity of the handle.