Abstract: An apparatus includes a portable case, and a slide-out printer is connected to the portable case. The slide-out printer is connected so as to slide in and out of the portable case. The slide-out printer includes a scanner, and the scanner includes a platen. The apparatus also includes a slide-out shredder connected to the portable case. The slide-out shredder is similarly connected to slide in and out of the portable case.

Abstract: A method in a reconfigurable computing system includes connecting a plurality of tensor consumers to their corresponding tensor producers via skip-buffers, which generates a plurality of skip-buffers. The method includes determining that at least one skip-buffer of the plurality of skip-buffers corresponding to a first set of tensor consumers and at least one skip-buffer of the plurality of skip-buffers corresponding to a second set of tensor consumers, are compatible to wholly or partially merge. The method also includes merging, wholly or partially, the compatible skip-buffers to produce a merged skip-buffer having a minimal buffer depth. The described method may reduce memory unit consumption and latency.

Abstract: An alignment system for a putter-type golf club head including a plurality of focus elements. The alignment system focuses the player’s eye proximate the ball at address to improve putting performance.

Abstract: A method to measure a cognitive load based upon ocular information of a subject includes the steps of: providing a video camera configured to record a close-up view of at least one eye of the subject; providing a computing device electronically connected to the video camera and the electronic display; recording, via the video camera, the ocular information of the at least one eye of the subject; processing, via the computing device, the ocular information to identify changes in ocular signals of the subject through the use of convolutional neural networks; evaluating, via the computing device, the changes in ocular signals from the convolutional neural networks by a machine learning algorithm; determining, via the machine learning algorithm, the cognitive load for the subject; and displaying, to the subject and/or to a supervisor, the cognitive load for the subject.

Abstract: A seed sampling system is provided comprising an automated seed loading assembly operable to singulate seeds from a plurality of seeds or enable loading of individually stored seeds and an automated seed sampling assembly comprising at least one sampling module operable to remove tissue samples from one of the singulated seeds. The system also includes an automated seed transport assembly comprising at least one retention member operable to transfer the singulated seeds from at least one elevator unit of the seed loading assembly to the at least one sampling module of the seed sampling assembly. In connection therewith, the at least one sampling module includes multiple sampling locations, each associated with a sampler, where the at least one sampling module is operable to remove tissue samples from seeds at one of sampling locations while another one of the sampling locations is cleaned to remove residual seed tissue therefrom.

Abstract: Abstract: A method for reducing variation in whole plant nitrogen includes providing, to a locus,a plurality of crop plants and a plurality of nitrogen fixing microbes that colonize the rhizosphere of said plurality of crop plants and supply the plants with fixed N. The variation in whole plant nitrogen of the plurality of crop plants colonized by said nitrogen fixing microbes, at a given growth stage and as measured across the locus, is lower than a variation in whole plant nitrogen of a control plurality of crop plants, when the control plurality of crop plants is provided to the locus.

Abstract: Disclosed herein are compositions and methods for topical delivery of mTOR inhibitors. In one embodiment, an anhydrous composition includes one or more mTOR inhibitors, one or more solvents, one or more gelling agents, and one or more antioxidants. Also disclosed herein are methods to treat skin disorders using such compositions.

Abstract: The disclosure provides methods for treating muscular dystrophy (MD), such as Duchenne muscular dystrophy (DMD) or Becker muscular dystrophy (BMD) in a mammalian subject. The methods are particularly useful for treating, inhibiting, reducing, ameliorating or delaying the onset of hypertrophic cardiomyopathy, dilated cardiomyopathy, heart failure and/or cardiac fibrosis in subjects diagnosed with, and/or being treated for, MD.The methods comprise administering to the subject an effective amount of a peptide such as H-D-Arg-2,6-Dmt-Lys-PHe-NH2 (a.k.a. elamipretide), or a pharmaceutically acceptable salt, hydrate, solvate and/or tautomer thereof, optionally in combination with at least one other active ingredient (i.e. drug) such a corticosteroid, ACE inhibitor, ARB(s), beta-blocker or drug that increases or corrects the expression of dystrophin in the subject (e.g. Eteplirsen (Exondys 51®), Golodirsen (Vyondys 53™)) or Casimersen (Amondys 45™).

Abstract: This invention is directed to compounds of formula (I): where r, q, R, R2, R3, R4, R5a, R5b, R5c, R6a, R6b, R6c, R7, R8, and R9 are described herein, as single stereoisomers or as mixtures of stereoisomers, or pharmaceutically acceptable salts, solvates, clathrates, polymorphs, ammonium ions, N-oxides or prodrugs thereof; which are leukotriene A4 hydrolase inhibitors and therefore useful in treating inflammatory disorders. Pharmaceutical compositions comprising the compounds of the invention and methods of preparing the compounds of the invention are also disclosed.

Abstract: In the present disclosure, described is an electrolyte for an electrochemical cell comprising a solvent mixture comprising at least two carbonate solvents. Disclosed is also an electrolyte for an electrochemical cell comprising a solvent mixture comprising co-solvent DMC, co-solvent EC, and co-solvent PC, and additives SCN and FEC, wherein the mass % of each of additives SCN and FEC are less than 5%.

Abstract: Implementations set forth herein relate to an automated assistant that can provide suggestions for a user to interact with the automated assistant to control applications while in a vehicle. The suggestions can be provided to encourage hands-free interactions with the applications, by suggesting an assistant input that invokes the automated assistant to operate as an interface between the user and the applications. Assistant suggestions can be based on a context of a user and/or a context of the vehicle, such as content of a display interface of a device that the user is accessing while in the vehicle. For instance, the automated assistant can determine that an action that the user has employed an application to perform can be initialized more safely and/or in less time by utilizing a particular assistant input. This particular assistant input can then be rendered at an interface of a vehicle computing device.

Abstract: This invention relates to the large-scale production of psilocybin for use in medicine. More particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly, in the form of Polymorph A. It further relates to a method for the manufacture of psilocybin and intermediates in the production thereof and formulations containing psilocybin.

Abstract: A therapeutic molecule (single chain-based antibody or ligand-based) optimized for expression and secretion from engineered T cells, which may be gamma delta (gd) T cells. When expressed from engineered gdT cells, the STAR will be secreted and mediate engagement between gdT cells and antigen/receptor on target cells. Binding mediates the formation of a cytolytic synapse between the gdT cell and the target cell leading to activation the gdT cells to release proteolytic enzymes that kill target cells.

Abstract: A wirelessly-controlled jamb-mounted access control system can include an in-jamb housing, a lock body at least partially inside the housing and rotatable about a first axis between locked and unlocked positions. The first axis can extend parallel to the jamb, and the lock body can include inner and outer sidewalls that define a latch cavity configured to receive a latch tongue of a door. The wirelessly-controlled j amb-mounted access control system can further include an actuator configured to control release of the lock body from the locked position in response to a control signal.

Abstract: An illustrative application executing on a first device establishes a first network connection between the first device and a collaboration platform server managing a set of components for a collaboration platform providing voice communication services with respect to a virtual space. Using the first network connection, the application: 1) sets a first location within the virtual space at which a first voice component is positioned, and 2) determines a second location within the virtual space at which a second voice component is positioned. The application receives, by way of a second network connection between the first and second devices, audio data representing voice communication originating at the second device. Based on the first and second locations, the application generates a spatialized rendering of the audio data for presentation to a user. Corresponding methods and systems are also disclosed.

Abstract: Per- and polyfluoroalkyl substances (PFAS) are destroyed by oxidation in supercritical conditions. PFAS in water can be concentrated and prepared for destruction in a pretreatment phase. Following annihilation of the PFAS in supercritical conditions to levels below 5 parts per trillion (ppt), the water effluent can be used to recover heat, returned to sub-critical conditions, and then released back into the environment.

Abstract: Per- and polyfluoroalkyl substances (PFAS) are destroyed by oxidation in supercritical conditions. PFAS in water can be concentrated and prepared for destruction in a pretreatment phase. Following annihilation of the PFAS in supercritical conditions to levels below 5 parts per trillion (ppt), the water effluent can be used to recover heat, returned to sub-critical conditions, and then released back into the environment.

Abstract: There is disclosed a nanopore support structure comprising a wall layer comprising walls defining a plurality of wells, and overhangs extending from the walls across each of the wells, the overhang defining an aperture configured to support a membrane suitable for insertion of a nanopore. There is further disclosed a nanopore sensing device comprising a nanopore support structure, and methods of manufacturing the nanopore support structure and the nanopore sensing device.

Abstract: A method according to an embodiment includes receiving UWB data by an access control device, performing predictive analysis on the UWB data to generate expected location data associated with a location of a mobile device, determining a velocity of the mobile device and a heading of the mobile device based on the UWB data, determining whether the mobile device is on course to a passageway associated with the access control device based on the velocity and the heading of the mobile device, performing state estimation to determine whether the mobile device is within a secure distance threshold from the passageway, wherein the secure distance threshold dynamically changes based on the velocity of the mobile device, and inferring ingress intent of a user of the mobile device in response to determining that the mobile device is within the secure distance threshold and on course to the passageway.

Abstract: Provided are imaging agents comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof, and methods of their use.