Abstract: The disclosure contained herein describes systems, units, and methods usable to stimulate a formation including a pump usable to pressurize fluid, an electric-powered driver in communication with and actuating the pump, and an electrical power source in communication with and powering the electric-powered driver. The electrical power source can include on-site generators and/or grid power sources, and transformers can be used to alter the voltage received to a voltage suitable for powering the electric-powered driver. Air moving devices associated with the electric-powered driver can be used to provide air proximate to the pump to disperse gasses. In combination with fluid supply and/or proppant addition subsystems, the pump can be used to fracture a formation.

Abstract: The present invention provides a skin surface sampling device in which a supply tube and a recovery tube are housed in an elongated hand-holdable tubular sleeve, the sleeve having upper and lower ends positioned along a longitudinal axis and the lower end being provided with a sampling head; in which: the supply tube is adapted to convey liquid from a liquid source to the sampling head; the recovery tube is adapted to convey liquid from the sampling head to a liquid collection vessel; the sampling head has a planar surface adapted for application to the surface of the skin to form a contact therewith during sampling; the planar surface has a liquid entry port adapted for liquid communication with the supply tube and a liquid exit port adapted for liquid communication with the recovery tube; and characterised in that: the liquid entry port and the liquid exit port are connected via a guide channel which is adapted to guide liquid from the liquid entry port, along the surface of the skin for the elution of mate

Abstract: Certain aspects of an apparatus and method for Internet protocol (IP) video signal synchronization may include a server or switching center. The method for synchronized transmission of content may include receiving a plurality of content streams and a request to switch the transmission of content. The plurality of content streams may be received from a plurality of sources. The request to switch may switch the transmission of content from a first content stream to a second content stream of the received plurality of content streams. A time delay may be determined to be added to the transmission of content to compensate for a propagation delay of the received request and a processing delay to process the received request.

Abstract: Disclosed are substituted pyridine compounds as well as pharmaceutical compositions and methods of use. One embodiment is a compound having the structure wherein E, J, T, the ring system denoted by “B”, T, R3, R4, w and x are as described herein. In certain embodiments, a compound disclosed herein activates the AMPK pathway, and can be used to treat metabolism-related disorders and conditions.

Abstract: Disclosed are substituted pyridine compounds as well as pharmaceutical compositions and methods of use. One embodiment is a compound having the structure wherein E, J, T, the ring system denoted by “B”, T, R3, R4, w and x are as described herein. In certain embodiments, a compound disclosed herein activates the AMPK pathway, and can be used to treat metabolism-related disorders and conditions.

Abstract: The invention encompasses compounds having formula I and the compositions and methods using these compounds in the treatment of conditions in which modulation of the JAK pathway or inhibition of JAK kinases, particularly JAK3, are therapeutically useful.

Abstract: A method and apparatus are disclosed for sharing an integrity security module in a dual-environment computing device. The apparatus include an integrity security module, one or more processors, a detection module and a regeneration module. The one or more processors may have access to the integrity security module and may operate in two distinct operating environments of a dual-environment computing device. The detection module may detect, during an initialization sequence, a power state transition of an operating environment of the dual-environment computing device. The regeneration module may regenerate one or more integrity values from a stored integrity metric log in response to detecting the power state transition of the operating environment of the dual-environment computing device.

Abstract: The present invention provides 2,4-pyrimidinediamine compounds having antiproliferative activity, compositions comprising the compounds and methods of using the compounds to inhibit cellular proliferation and to treat proliferative diseases such as tumorigenic cancers.

Abstract: The disclosure relates particularly to certain carboxamide, sulfonamide and amine compounds and pharmaceutical compositions thereof, and to methods of treating and ameliorating disorders and conditions related to the adiponectin pathway, sphingolipid metabolism, oxidative stress, mitochondrial dysfunction, free radical damage and metabolic inefficiency, among others. In certain embodiments, the compounds have the structures (I-1), (2-I) and (3-I) (The chemical formulas should be inserted here) in which the variables are as described herein.

Abstract: Disclosed herein methods, apparatuses, and systems for performing graphics processing. In this regard, a processing unit includes a tessellation module and a connectivity module. The tessellation module is configured to sequentially tessellate portions of a geometric shape to provide a series of tessellation points for the geometric shape. The connectivity module is configured to connect one or more groups of the tessellation points into one or more primitives in an order in which the series of tessellation points is provided.

Abstract: Disclosed are substituted pyridine compounds as well as pharmaceutical compositions and methods of use. One embodiment is a compound having the structure wherein E, J, T, the ring system denoted by “B”, T, R3, R4, w and x are as described herein. In certain embodiments, a compound disclosed herein activates the AMPK pathway, and can be used to treat metabolism-related disorders and conditions.

Abstract: The invention encompasses compounds having formula I-V and the compositions and methods using these compounds in the treatment of conditions in which modulation of the JAK pathway or inhibition of JAK kinases, particularly JAK3, may be therapeutically useful.

Abstract: Methods, systems, and computer readable media embodiments are disclosed for generating primitives in a grid. Embodiments include generating a set of vertices in a section of the grid, selecting one or more vertices in the set of vertices in an order based on a proximity of the vertices to a boundary edge of the grid, and generating primitives based on the order of the selected vertices.

Abstract: The invention encompasses compounds having formula I-V and the compositions and methods using these compounds in the treatment of conditions in which modulation of the JAK pathway or inhibition of JAK kinases, particularly JAK3, may be therapeutically useful.

Abstract: The invention encompasses compounds having formula I and the compositions and methods using these compounds in the treatment of conditions in which modulation of the JAK pathway or inhibition of JAK kinases are therapeutically useful.

Abstract: Disclosed are substituted pyridine compounds as well as pharmaceutical compositions and methods of use. One embodiment is a compound having the structure wherein E, J, T, the ring system denoted by “B”, T, R3, R4, w and x are as described herein. In certain embodiments, a compound disclosed herein activates the AMPK pathway, and can be used to treat metabolism-related disorders and conditions.

Abstract: The present invention provides 2,4-pyrimidinediamine compounds having antiproliferative activity, compositions comprising the compounds and methods of using the compounds to inhibit cellular proliferation and to treat proliferative diseases such as tumorigenic cancers.

Abstract: Software code changes are facilitated by receiving as input a user query specifying a search term and automatically generating a ranked list of connected call trees based on the search term. Each connected call tree identifies subroutines that contain an identifier matching at least part of the search term or that are linked to a subroutine that contains an identifier matching at least part of the search term. The ranked list of connected call trees is displayed as a diagram.

Abstract: Disclosed are substituted pyridine compounds as well as pharmaceutical compositions and methods of use. One embodiment is a compound having the structure wherein E, J, T, the ring system denoted by “B”, T, R3, R4, w and x are as described herein. In certain embodiments, a compound disclosed herein activates the AMPK pathway, and can be used to treat metabolism-related disorders and conditions.

Abstract: The invention encompasses compounds having formula I and the compositions and methods using these compounds in the treatment of conditions in which modulation of the JAK pathway or inhibition of JAK kinases are therapeutically useful.