Patents by Inventor David Cox

David Cox has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Assessment and dynamic provisioning of computing resources for multi-tiered application
    Patent number: 10439870
    Abstract: Systems and methods for allocating computing resources for a multi-tiered application are disclosed. A computer-implemented method includes: determining, by a computing device, a topology of a multi-tiered application; determining, by the computing device, a modeled setting of a computing resource for the multi-tiered application based on the determined topology; determining, by the computing device, an actual usage of the computing resource by the multi-tiered application; and adjusting, by the computing device, an allocation of the computing resource to the multi-tiered application based on the actual usage and the modeled setting.
    Type: Grant
    Filed: November 24, 2015
    Date of Patent: October 8, 2019
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Danny Y. Chen, David A. Cox, Brent R. Phillips, John H. Smith
  • SOFTWARE DEPLOYMENT TO MULTIPLE COMPUTING DEVICES
    Publication number: 20190294424
    Abstract: A particular method includes storing a manifest file and a parameters file at a data store. The manifest file and the parameters file are associated with a software deployment package. An application associated with the software deployment package is published to a first remote computing device and to a second remote computing device. The method includes receiving first parameter values from the first remote computing device and receiving second parameter values from the second remote computing device. The first parameter values are stored in a first region of the data store that is specific to the first computing device. The second parameter values are stored in a second region of the data store that is specific to the second computing device.
    Type: Application
    Filed: April 8, 2019
    Publication date: September 26, 2019
    Inventors: Madhur Joshi, Crystal Hoyer, David Cox, Mohammed Parvez Shaikh, Emily B. Repperger, Yamini Jagadeesan, Muhammad Bilal Aslam, Clea Allington, Yishai Galatzer
  • Markers for breast cancer
    Patent number: 10407738
    Abstract: Correlations between polymorphisms and breast cancer are provided. Methods of diagnosing, prognosing, and treating breast cancer are provided. Systems and kits for diagnosis, prognosis and treatment of breast cancer are provided. Methods of identifying breast cancer modulators are also described.
    Type: Grant
    Filed: June 7, 2017
    Date of Patent: September 10, 2019
    Assignee: Cambridge Enterprise Limited
    Inventors: David Cox, Dennis Ballinger, Bruce Ponder, Doug Easton
  • METHODS AND SYSTEMS FOR NUCLEIC ACID ANALYSIS AND QUANTIFICATION
    Publication number: 20190264260
    Abstract: The present disclose provides methods and systems for amplifying and quantifying nucleic acids and for detecting the presence or absence of a target in a sample. The methods and systems provided herein may utilize a device comprising a plurality of partitions separated from an external environment by a gas-permeable barrier. Certain methods disclosed herein involve subjecting nucleic acid molecules in the plurality of partitions to conditions sufficient to conduct nucleic acid amplification reactions. The nucleic acid molecules may be subjected to controlled heating in the plurality of partitions to generate data indicative of a melting point(s) of the nucleic acid molecules.
    Type: Application
    Filed: May 9, 2019
    Publication date: August 29, 2019
    Inventors: Andrew Zayac, Ju-Sung Hung, Howard Gregg King, David Cox
  • UTILITY LOCATOR DEVICES, SYSTEMS, AND METHODS WITH SATELLITE AND MAGNETIC FIELD SONDE ANTENNA SYSTEMS
    Publication number: 20190257975
    Abstract: A transmitter system for providing current to a utility when performing a locate operation is disclosed. The transmitter system may include a tray apparatus, a transmitter module for generating an output current for provision to the utility so as to generate a magnetic field for detection by a utility locator disposed on or in the tray apparatus, and a sonde antenna node, a satellite antenna node, or a combined satellite navigation and sonde antenna node.
    Type: Application
    Filed: July 15, 2015
    Publication date: August 22, 2019
    Inventors: Mark S. Olsson, Jesse O. Casares, Jan Soukup, Stephanie M. Bench, Ray Merewether, David A. Cox, Justin W. Taylor
  • SYSTEMS AND METHODS FOR MACHINE LEARNING ENHANCED BY HUMAN MEASUREMENTS
    Publication number: 20190236413
    Abstract: In various embodiments, training objects are classilied by human annotators, psychometric data characterizing the annotation of the training objects is acquired, a human-weighted loss function based at least in part on the colassification data and the psychometric data is computationally derived, and one or more features of a query object are computationally classified based at least its part on the human-weighted loss function.
    Type: Application
    Filed: April 11, 2019
    Publication date: August 1, 2019
    Inventors: David COX, Walter SCHEIRER, Samuel ANTHONY, Ken NAKAYAMA
  • METHODS AND APPARATUS FOR THE DELIVERY OF HEPATITIS B VIRUS (HBV) VACCINES
    Publication number: 20190184010
    Abstract: Methods and apparatus for the reproducible, consistent and efficacious delivery of an HBV vaccine to a subject. The disclosure comprises apparatus for the controlled administration of the HBV vaccine through an orifice to the subject, a plurality of penetrating electrodes arranged with a predetermined spatial relationship relative to the orifice, and an electrical signal generator operatively connected to the electrodes.
    Type: Application
    Filed: December 18, 2018
    Publication date: June 20, 2019
    Inventors: Daniel Boden, Helen Horton, Jean-Marc Edmond Fernand Marie Neefs, Soumitra Roy, Andrew W. Hannaman, Robert M. Bernard, Stephen A. Morse, Oliver Ruck, Adam Hartman, Thomas David Cox
  • Ground tracking devices and methods for use with a utility locator
    Patent number: 10317559
    Abstract: A ground tracking apparatus for connection to a locator or other measurement device and configured to determine position, motion, and/or orientation information is disclosed. The ground tracking apparatus may include a ground follower assembly including one or more wheels, which may be detachably coupled to a buried object locator system to capture three-dimensional positional and orientation information during a locate process, as well as provide output data or information to be integrated with maps, photographs, drawings, or other data or information.
    Type: Grant
    Filed: June 26, 2017
    Date of Patent: June 11, 2019
    Assignee: SEESCAN, INC.
    Inventors: Mark S. Olsson, David A. Cox, Ryan B. Levin, Ray Merewether, Sequoyah Aldridge
  • Systems and methods for machine learning enhanced by human measurements
    Patent number: 10303982
    Abstract: In various embodiments, training objects are classified by human annotators, psychometric data characterizing the annotation of the training objects is acquired, a human-weighted loss function based at least in part on the classification data and the psychometric data is computationally derived, and one or more features of a query object are computationally classified based at least in part on the human-weighted loss function.
    Type: Grant
    Filed: July 25, 2018
    Date of Patent: May 28, 2019
    Assignee: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: David Cox, Walter Scheirer, Samuel Anthony, Ken Nakayama
  • Continuous publication of application to remote computing devices
    Patent number: 10296317
    Abstract: A particular method includes storing a manifest file and a parameters file at a data store. The manifest file and the parameters file are associated with a software deployment package. An application associated with the software deployment package is published to a first remote computing device and to a second remote computing device. The method includes receiving first parameter values from the first remote computing device and receiving second parameter values from the second remote computing device. The first parameter values are stored in a first region of the data store that is specific to the first computing device. The second parameter values are stored in a second region of the data store that is specific to the second computing device.
    Type: Grant
    Filed: December 20, 2010
    Date of Patent: May 21, 2019
    Assignee: Microsoft Technology Licensing, LLC
    Inventors: Madhur Joshi, Crystal Hoyer, David Cox, Mohammed Parvez Shaikh, Emily B. Repperger, Yamini Jagadeesan, Muhammad Bilal Aslam, Clea Allington, Yishai Galatzer
  • BURIED OBJECT LOCATING DEVICES AND METHODS
    Publication number: 20190137644
    Abstract: A buried object locator which may include at least one antenna array including three orthogonal antennas, each antenna sharing a common center point, is disclosed. An electronic circuit may be connected to the array and used to determine location information of the buried objects by measuring signal strength and magnetic field angular data in three dimensions.
    Type: Application
    Filed: May 28, 2018
    Publication date: May 9, 2019
    Inventors: Mark S. Olsson, Dawn E. Shaffer, Ray Merewether, Michael J. Martin, David A. Cox
  • Utility locator transmitter apparatus and methods
    Patent number: 10247845
    Abstract: A high-Q human-portable, battery-powered self-correcting tunable transmitter apparatus for inducing alternating currents in buried conductors to facilitate their location is disclosed.
    Type: Grant
    Filed: December 30, 2016
    Date of Patent: April 2, 2019
    Assignee: SEESCAN, INC.
    Inventors: Ray Merewether, Mark S. Olsson, Jan Soukup, Ryan B. Levin, David A. Cox
  • Use of eribulin and poly (ADP ribose) polymerase (PARP) inhibitors as combination therapy for the treatment of cancer
    Patent number: 10238630
    Abstract: The invention features methods for treating cancer in a patient in need thereof by administering eribulin, in combination with one or more PARP inhibitors, and, optionally, a platinum-based antineoplastic drug, and kits therefor. The invention is based in part on the observation that combinations of eribulin mesylate, a PARP inhibitor (e.g., E7449), and, optionally, a platinum-based antineo-plastic drug (e.g., carboplatin), show improved (e.g., synergistic) antitumor effects. Therefore, the present invention features methods of preventing and treating cancer (e.g., homologous recombination (HR)-deficient cancer by the use of combinations of eribulin (e.g., eribulin mesylate) and one or more PARP inhibitors (e.g., E7449 or a pharmaceutically acceptable salt thereof (e.g., the tartrate salt), optionally in combination with a platinum-based antineoplastic drug (e.g., carboplatin).
    Type: Grant
    Filed: May 28, 2015
    Date of Patent: March 26, 2019
    Assignee: EISAI R&D MANAGEMENT CO., LTD.
    Inventors: David Cox, Alton Kremer, Sharon McGonigle, Jiayi Wu
  • UTILITY LOCATING TRANSMITTER APPARATUS & METHODS
    Publication number: 20190041538
    Abstract: A high-Q human-portable, battery-powered self-correcting tunable transmitter apparatus for inducing alternating currents in buried conductors to facilitate their location is disclosed.
    Type: Application
    Filed: January 22, 2018
    Publication date: February 7, 2019
    Inventors: Ray Merewether, Mark S. Olsson, Jan Soukup, Ryan B. Levin, David A. Cox
  • METHOD AND APPARATUS FOR DELIVERY OF THERAPEUTIC AGENTS
    Publication number: 20190030329
    Abstract: Methods and apparatus for the reproducible, consistent and efficacious delivery of a therapeutic agent to a subject. The present disclosure comprises apparatus for the controlled administration of the therapeutic agent through an orifice to the subject, a plurality of penetrating electrodes arranged with a predetermined spatial relationship relative to the orifice, and an electrical signal generator operatively connected to the electrodes.
    Type: Application
    Filed: September 27, 2018
    Publication date: January 31, 2019
    Inventors: Andrew W. HANNAMAN, Robert M. BERNARD, Stephen A. MORSE, Oliver RUCK, Adam HARTMAN, Thomas David COX
  • Adjustable variable resolution inspection systems and methods
    Patent number: 10175177
    Abstract: Camera heads configured to provide digitally articulated images or video, at adjustable resolutions and/or offsets and orientations, to a camera control unit (CCU) or other electronic computing system for display, storage, and/or transmission to other systems are disclosed.
    Type: Grant
    Filed: June 24, 2015
    Date of Patent: January 8, 2019
    Assignee: SEESCAN, INC.
    Inventors: Mark S. Olsson, Scott A Powell, Stephanie M Bench, Ray Merewether, David A Cox, Eric M Chapman
  • METHOD FOR THE PROTECTION OF TREES
    Publication number: 20180360044
    Abstract: The present invention provides a method for the prevention/treatment of bark beetle and/or wood borer infestation of trees comprising treatment of the tree with a composition comprising a macroyclic lactone.
    Type: Application
    Filed: August 22, 2018
    Publication date: December 20, 2018
    Applicant: Syngenta Participations AG
    Inventors: Donald M. Grosman, David Cox
  • SYSTEMS AND METHODS FOR MACHINE LEARNING ENHANCED BY HUMAN MEASUREMENTS
    Publication number: 20180357515
    Abstract: In various embodiments, training objects are classified by human annotators, psychometric data characterizing the annotation of the training objects is acquired, a human-weighted loss function based at least in part on the classification data and the psychometric data is computationally derived, and one or more features of a query object are computationally classified based at least in part on the human-weighted loss function.
    Type: Application
    Filed: July 25, 2018
    Publication date: December 13, 2018
    Inventors: David COX, Walter SCHEIRER, Samuel ANTHONY, Ken NAKAYAMA
  • Identification of Glycosylation Forms
    Publication number: 20180299461
    Abstract: The present teachings relate to methods, systems, and kits for analyzing a sample containing a glycopeptide of interest that can subject the glycopeptide of interest to a plurality of parallel deglycosylation reactions that differentially cleave the glycan, with the various products resulting from the deglycosylation reactions being differentially labeled (e.g., with isobaric and/or isomeric labeling reagents) to thereby produce labeled glycopeptides or labeled fragments of the glycopeptides. The products of the various deglycosylation reactions can then be mixed together and subject to LC-MS/MS using a single injection of the mixture. In accordance with various aspects, by associating the resulting mass spectral data with a particular deglycosylation reaction (e.g.
    Type: Application
    Filed: April 25, 2016
    Publication date: October 18, 2018
    Inventor: David Cox
  • Modular battery pack apparatus, systems, and methods including viral data and/or code transfer
    Patent number: 10090498
    Abstract: Intelligent modular battery pack assemblies and associated charging and docking systems are disclosed. In one embodiment a modular battery pack assembly may include an outer casing assembly, a thermally conductive structural housing element configured to house a battery assembly in an interior volume, a lid element configured to cover the opening in the thermally conductive structural housing element and mechanically strengthen the thermally conductive structural housing element, and a circuit element disposed to electrically couple the battery cell to a battery-powered device and provide viral data transfer between the battery and a coupled device.
    Type: Grant
    Filed: June 24, 2013
    Date of Patent: October 2, 2018
    Assignee: SEESCAN, INC.
    Inventors: Mark S. Olsson, David A. Cox, Alexander L. Warren, Joseph B. Phaneuf