Patents by Inventor David J. Mishelevich

David J. Mishelevich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10643497
    Abstract: Systems and methods are disclosed for an apparatus and method for practicing injection techniques through an injectable apparatus. The injectable apparatus may contain a camera that is configured to detect the intensity and color of light attenuated from a testing tool after it is injected into a simulated human or animal body parts. A training tool may be connected to a user display device to generate a display of the injection apparatus as well as the performance parameters of a trainee.
    Type: Grant
    Filed: May 11, 2018
    Date of Patent: May 5, 2020
    Assignee: Truinject Corp.
    Inventors: Gabrielle A. Rios, Jeff Crockett, Clark B. Foster, Milan Trcka, David J. Mishelevich, Aaron J. Gifford, Chris C. Ludolph
  • Patent number: 10596310
    Abstract: The specification discloses a portable dialysis machine having a detachable controller unit and base unit. The controller unit includes a door having an interior face, a housing with a panel, where the housing and panel define a recessed region configured to receive the interior face of the door, and a manifold receiver fixedly attached to the panel. The base unit has a planar surface for receiving a container of fluid, a scale integrated with the planar surface, a heater in thermal communication with the planar surface, and a sodium sensor in electromagnetic communication with the planar surface. Embodiments of the disclosed portable dialysis system have improved structural and functional features, including improved modularity, ease of use, and safety features.
    Type: Grant
    Filed: November 2, 2016
    Date of Patent: March 24, 2020
    Assignee: Fresenius Medical Care Holdings, Inc.
    Inventors: Barry Neil Fulkerson, James Roswell Braig, David J Mishelevich, Charles Clemens, Clark Berg Foster, Martin Hering, Jan Brian Zwierstra, Russell Thomas Joseph, Victor Gura, Thomas Robinson, Milan Trcka, Daniele Ghidoli, Frank Isackson, Mark Forrest Smith
  • Patent number: 10569099
    Abstract: Stimulation of target cells using light, e.g., in vivo, is implemented using a variety of methods and devices. According to an example embodiment of the present invention, target cells are stimulated using an implantable arrangement. The arrangement includes an electrical light-generation means for generating light and a biological portion. The biological portion has a photosensitive bio-molecular arrangement that responds to the generated light by stimulating target cells in vivo.
    Type: Grant
    Filed: November 10, 2014
    Date of Patent: February 25, 2020
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Karl Deisseroth, M. Bret Schneider, David J. Mishelevich
  • Publication number: 20190321651
    Abstract: Stimulation of target cells using light, e.g., in vivo, is implemented using a variety of methods and devices. According to an example embodiment of the present invention, target cells are stimulated using an implantable arrangement. The arrangement includes an electrical light-generation means for generating light and a biological portion. The biological portion has a photosensitive bio-molecular arrangement that responds to the generated light by stimulating target cells in vivo.
    Type: Application
    Filed: May 6, 2019
    Publication date: October 24, 2019
    Inventors: Karl Deisseroth, Michael Bret Schneider, David J. Mishelevich
  • Patent number: 10290232
    Abstract: Various systems and methods are provided for injection training by collecting, processing, analyzing and displaying measured information associated with the delivery of an injection. Sensor-based measurements of a syringe's position and orientation in three-dimensional space are obtained and processed to provide metrics of a trainee's injection performance. The measurements can be combined with a digital model of a training apparatus to deliver a computer-generated, graphical depiction of the training injection, enabling visualization of the injection from perspectives unavailable in the physical world. The training injection execution, as reflected in the measured sensor-based data, can be reviewed and analyzed at times after, and in locations different than, the time and location of the training injection. Additionally, injection training data associated with multiple training injections can be aggregated and analyzed for, among other things, trends in performance.
    Type: Grant
    Filed: May 14, 2018
    Date of Patent: May 14, 2019
    Assignee: TruInject Corp.
    Inventors: Gabrielle A. Rios, David J. Mishelevich, Clark B. Foster
  • Patent number: 10290231
    Abstract: Various systems and methods are provided for injection training by collecting, processing, analyzing and displaying measured information associated with the delivery of an injection. Sensor-based measurements of a syringe's position and orientation in three-dimensional space are obtained and processed to provide metrics of a trainee's injection performance. The measurements can be combined with a digital model of a training apparatus to deliver a computer-generated, graphical depiction of the training injection, enabling visualization of the injection from perspectives unavailable in the physical world. The training injection execution, as reflected in the measured sensor-based data, can be reviewed and analyzed at times after, and in locations different than, the time and location of the training injection. Additionally, injection training data associated with multiple training injections can be aggregated and analyzed for, among other things, trends in performance.
    Type: Grant
    Filed: March 12, 2015
    Date of Patent: May 14, 2019
    Assignee: TruInject Corp.
    Inventors: Gabrielle A. Rios, David J. Mishelevich, Clark B. Foster
  • Publication number: 20180326221
    Abstract: Stimulation of target cells using light, e.g., in vivo, is implemented using a variety of methods and devices. In one example, embodiments involve methods for stimulating target cells using a photosensitive protein that allows the target cells to be stimulated in response to light. In another specific example embodiment, target cells are stimulated using an implantable arrangement. The arrangement includes an electrical light-generation means for generating light and a biological portion. The biological portion has a photosensitive bio-molecular arrangement that responds to the generated light by stimulating target cells in vivo. Other aspects and embodiments are directed to systems and methods for screening chemicals based screening chemicals to identify their effects on cell membrane ion channels and pumps, and to systems and methods for controlling an action potential of neuron (e.g., in vivo and in vitro environments).
    Type: Application
    Filed: July 20, 2018
    Publication date: November 15, 2018
    Inventors: Karl Deisseroth, Feng Zhang, David J. Mishelevich, M. Bret Schneider
  • Publication number: 20180261125
    Abstract: Systems and methods are disclosed for an apparatus and method for practicing injection techniques through an injectable apparatus. The injectable apparatus may contain a camera that is configured to detect the intensity and color of light attenuated from a testing tool after it is injected into a simulated human or animal body parts. A training tool may be connected to a user display device to generate a display of the injection apparatus as well as the performance parameters of a trainee.
    Type: Application
    Filed: May 11, 2018
    Publication date: September 13, 2018
    Inventors: Gabrielle A. Rios, Jeff Crockett, Clark B. Foster, Milan Trcka, David J. Mishelevich, Aaron J. Gifford, Chris C. Ludolph
  • Publication number: 20180261126
    Abstract: Various systems and methods are provided for injection training by collecting, processing, analyzing and displaying measured information associated with the delivery of an injection. Sensor-based measurements of a syringe's position and orientation in three-dimensional space are obtained and processed to provide metrics of a trainee's injection performance. The measurements can be combined with a digital model of a training apparatus to deliver a computer-generated, graphical depiction of the training injection, enabling visualization of the injection from perspectives unavailable in the physical world. The training injection execution, as reflected in the measured sensor-based data, can be reviewed and analyzed at times after, and in locations different than, the time and location of the training injection. Additionally, injection training data associated with multiple training injections can be aggregated and analyzed for, among other things, trends in performance.
    Type: Application
    Filed: May 14, 2018
    Publication date: September 13, 2018
    Inventors: Gabrielle A. Rios, David J. Mishelevich, Clark B. Foster
  • Patent number: 10052497
    Abstract: Stimulation of target cells using light, e.g., in vivo, is implemented using a variety of methods and devices. In one example, embodiments involve methods for stimulating target cells using a photosensitive protein that allows the target cells to be stimulated in response to light. In another specific example embodiment, target cells are stimulated using an implantable arrangement. The arrangement includes an electrical light-generation means for generating light and a biological portion. The biological portion has a photosensitive bio-molecular arrangement that responds to the generated light by stimulating target cells in vivo. Other aspects and embodiments are directed to systems and methods for screening chemicals based screening chemicals to identify their effects on cell membrane ion channels and pumps, and to systems and methods for controlling an action potential of neuron (e.g., in in vivo and in vitro environments).
    Type: Grant
    Filed: January 9, 2008
    Date of Patent: August 21, 2018
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Karl Deisseroth, Feng Zhang, David J. Mishelevich, M. Bret Schneider
  • Publication number: 20170246481
    Abstract: Disclosed are methods and systems for optimized deep or superficial deep-brain stimulation using multiple therapeutic modalities impacting one or multiple points in a neural circuit to produce Long-Term Potentiation (LTP) or Long-Term Depression (LTD). Also disclosed are methods for treatment of clinical conditions and obtaining physiological impacts.
    Type: Application
    Filed: February 27, 2017
    Publication date: August 31, 2017
    Inventor: David J Mishelevich
  • Publication number: 20170232177
    Abstract: The specification discloses a portable dialysis machine having a detachable controller unit and base unit. The controller unit includes a door having an interior face, a housing with a panel, where the housing and panel define a recessed region configured to receive the interior face of the door, and a manifold receiver fixedly attached to the panel. The base unit has a planar surface for receiving a container of fluid, a scale integrated with the planar surface, a heater in thermal communication with the planar surface, and a sodium sensor in electromagnetic communication with the planar surface. Embodiments of the disclosed portable dialysis system have improved structural and functional features, including improved modularity, ease of use, and safety features.
    Type: Application
    Filed: November 2, 2016
    Publication date: August 17, 2017
    Inventors: Barry Neil Fulkerson, James Roswell Braig, David J Mishelevich, Charles Clemens, Clark Berg Foster, Martin Hering, Jan Brian Zwierstra, Russell Thomas Joseph, Victor Gura, Thomas Robinson, Milan Trcka, Daniele Ghidoli, Frank Isackson, Mark Forrest Smith
  • Publication number: 20170186339
    Abstract: Systems and methods are disclosed for an apparatus and method for practicing injection techniques through an injectable apparatus. The injectable apparatus may contain a camera that is configured to detect the intensity and color of light attenuated from a testing tool after it is injected into a simulated human or animal body parts. A training tool may be connected to a user display device to generate a display of the injection apparatus as well as the performance parameters of a trainee.
    Type: Application
    Filed: September 7, 2016
    Publication date: June 29, 2017
    Inventors: Gabrielle A. Rios, Jeff Crockett, Clark B. Foster, David J. Mishelevich, Milan Trcka, Aaron J. Gifford, Chris C. Ludolph
  • Publication number: 20170151443
    Abstract: Described herein are shaped coil TMS electromagnets formed by two bent magnetic coil loops joined at a vertex having an angle between the outer coil regions of the coils that is typically less than 120 degrees (e.g., between about 45 and about 70 degrees, 60 degrees, etc.). The vertex region shaped to optimize the magnetic field projected from the TMS electromagnet. For example, the vertex region may be horizontal or vertical. In some variations the vertex region is formed by re-arranging the conductive windings forming the two coils so that they are no longer arranged in the same columnar structure that they are in the other portions of the bent magnetic coil loops. These TMS electromagnets may be well suited for use in deep-brain Transcranial Magnetic Stimulation.
    Type: Application
    Filed: July 5, 2016
    Publication date: June 1, 2017
    Inventors: David J. MISHELEVICH, M. Bret SCHNEIDER
  • Patent number: 9517296
    Abstract: The specification discloses a portable dialysis machine having a detachable controller unit and base unit. The controller unit includes a door having an interior face, a housing with a panel, where the housing and panel define a recessed region configured to receive the interior face of the door, and a manifold receiver fixedly attached to the panel. The base unit has a planar surface for receiving a container of fluid, a scale integrated with the planar surface, a heater in thermal communication with the planar surface, and a sodium sensor in electromagnetic communication with the planar surface. Embodiments of the disclosed portable dialysis system have improved structural and functional features, including improved modularity, ease of use, and safety features.
    Type: Grant
    Filed: September 27, 2013
    Date of Patent: December 13, 2016
    Assignee: Fresenius Medical Care Holdings, Inc.
    Inventors: Barry Neil Fulkerson, James Roswell Braig, David J Mishelevich, Charles Clemens, Clark Berg Foster, Martin Hering, Jan Brian Zwierstra, Russell Thomas Joseph, Victor Gura, Thomas Robinson, Milan Trcka, Daniele Ghidoli, Frank Isackson, Mark Forrest Smith
  • Publication number: 20160346610
    Abstract: A system and method for optimizing a patient's Kegel exercises is provided. The system includes a user interface device and a vaginal device. The vaginal device includes an intra-vaginal probe having an accelerometer that is configured to generate a signal in response to movement of the probe. The user interface device is connected to the vaginal device and analyzes signals from the accelerometer to provide physiological feedback information to the patient. The vaginal device may be connected to the user interface device via wireless communications such as Bluetooth or by wire. The user interface device may be a smart device or a computer that transmits information to central web-based data server accessible by the patient or authorized healthcare providers or third-party payers.
    Type: Application
    Filed: January 6, 2015
    Publication date: December 1, 2016
    Applicant: Remendium Labs LLC
    Inventors: Ramon Jose Iglesias, David J. Mishelevich, Sean C. Nash, Kaitlin B. Schaefer, Jahnavi Lokre, Milan V. Trcka, Himanshu Patel, Jan B. Zwierstra, Trevor Dunlop, Aaron Gifford
  • Patent number: 9486639
    Abstract: The present invention provides for Stereotactic Transcranial Magnetic Stimulation (sTMS) at predetermined locations with the brain or spinal cord and incorporates an array of electromagnets arranged in a specified configuration where selected coils in the array are pulsed simultaneously. Activation of foci demonstrated by functional MRI or other imaging techniques can be used to locate the neural region affected. Imaging techniques can also be utilized to determine the location of the designated targets.
    Type: Grant
    Filed: September 22, 2011
    Date of Patent: November 8, 2016
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: David J. Mishelevich, M. Bret Schneider
  • Patent number: 9445742
    Abstract: A device is described for measuring electrical characteristics of biological tissues with plurality of electrodes and a processor controlling the stimulation and measurement in order to detect the presence of abnormal tissue masses in organs. Examples of suitable organs are the breast, skin, oral cavity, lung, liver, colon, rectum, cervix, and prostate and determine probability of tumors containing malignant cancer cells being present in tissue. The approach can also be applied to biopsied tissue samples. The device has the capability of providing the location of the abnormality. The method for measuring electrical characteristics includes placing electrodes and applying a voltage waveform in conjunction with a current detector. A mathematical analysis method is then applied to the collected data, which computes spectrum of frequencies and correlates magnitudes and phases with given algebraic conditions to determine mass presence and type.
    Type: Grant
    Filed: May 22, 2015
    Date of Patent: September 20, 2016
    Inventors: Roman A. Slizynski, David J. Mishelevich
  • Patent number: 9443446
    Abstract: Systems and methods are disclosed for an apparatus and method for practicing injection techniques through an injectable apparatus. The injectable apparatus may contain a camera that is configured to detect the intensity and color of light attenuated from a testing tool after it is injected into a simulated human or animal body parts. A training tool may be connected to a user display device to generate a display of the injection apparatus as well as the performance parameters of a trainee.
    Type: Grant
    Filed: January 13, 2015
    Date of Patent: September 13, 2016
    Assignee: Trulnject Medical Corp.
    Inventors: Gabrielle A. Rios, Jeff Crockett, Clark B. Foster, David J. Mishelevich, Milan Trcka, Aaron J. Gifford, Chris C. Ludolph
  • Publication number: 20160220274
    Abstract: External fixation assemblies offer good benefits in relevant orthopedic procedures but would be used more efficiently if the quick-release fasteners could be used so no tools would be required. This invention covers various embodiments of quarter-turn, quick-release fasteners, various shapes and surfaces of connecting rods and bone pins or other clamped objects to facilitate use of external fixation assemblies. Included are quick-release fasteners constructed from programmable magnets. Connecting rods can have fastening positions in the form of threaded or non-threaded holes. Both holes and connecting rods and bone pins can be of different shapes, for example, round, square, oval, pentagonal, hexagonal, octagonal, or any arbitrary shape. In both adding holes and non-circular shapes, rotation is eliminated allowing better fixation, and, in the case of holes or dimpled or out-dented surfaces, longitudinal motion along the rod or pin as well.
    Type: Application
    Filed: March 27, 2016
    Publication date: August 4, 2016
    Inventors: Charles H. Lang, JR., David J. Mishelevich, Kevin Scott