Patents by Inventor David J. Mishelevich
David J. Mishelevich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10290232Abstract: Various systems and methods are provided for injection training by collecting, processing, analyzing and displaying measured information associated with the delivery of an injection. Sensor-based measurements of a syringe's position and orientation in three-dimensional space are obtained and processed to provide metrics of a trainee's injection performance. The measurements can be combined with a digital model of a training apparatus to deliver a computer-generated, graphical depiction of the training injection, enabling visualization of the injection from perspectives unavailable in the physical world. The training injection execution, as reflected in the measured sensor-based data, can be reviewed and analyzed at times after, and in locations different than, the time and location of the training injection. Additionally, injection training data associated with multiple training injections can be aggregated and analyzed for, among other things, trends in performance.Type: GrantFiled: May 14, 2018Date of Patent: May 14, 2019Assignee: TruInject Corp.Inventors: Gabrielle A. Rios, David J. Mishelevich, Clark B. Foster
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Patent number: 10290231Abstract: Various systems and methods are provided for injection training by collecting, processing, analyzing and displaying measured information associated with the delivery of an injection. Sensor-based measurements of a syringe's position and orientation in three-dimensional space are obtained and processed to provide metrics of a trainee's injection performance. The measurements can be combined with a digital model of a training apparatus to deliver a computer-generated, graphical depiction of the training injection, enabling visualization of the injection from perspectives unavailable in the physical world. The training injection execution, as reflected in the measured sensor-based data, can be reviewed and analyzed at times after, and in locations different than, the time and location of the training injection. Additionally, injection training data associated with multiple training injections can be aggregated and analyzed for, among other things, trends in performance.Type: GrantFiled: March 12, 2015Date of Patent: May 14, 2019Assignee: TruInject Corp.Inventors: Gabrielle A. Rios, David J. Mishelevich, Clark B. Foster
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Publication number: 20180326221Abstract: Stimulation of target cells using light, e.g., in vivo, is implemented using a variety of methods and devices. In one example, embodiments involve methods for stimulating target cells using a photosensitive protein that allows the target cells to be stimulated in response to light. In another specific example embodiment, target cells are stimulated using an implantable arrangement. The arrangement includes an electrical light-generation means for generating light and a biological portion. The biological portion has a photosensitive bio-molecular arrangement that responds to the generated light by stimulating target cells in vivo. Other aspects and embodiments are directed to systems and methods for screening chemicals based screening chemicals to identify their effects on cell membrane ion channels and pumps, and to systems and methods for controlling an action potential of neuron (e.g., in vivo and in vitro environments).Type: ApplicationFiled: July 20, 2018Publication date: November 15, 2018Inventors: Karl Deisseroth, Feng Zhang, David J. Mishelevich, M. Bret Schneider
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Publication number: 20180261126Abstract: Various systems and methods are provided for injection training by collecting, processing, analyzing and displaying measured information associated with the delivery of an injection. Sensor-based measurements of a syringe's position and orientation in three-dimensional space are obtained and processed to provide metrics of a trainee's injection performance. The measurements can be combined with a digital model of a training apparatus to deliver a computer-generated, graphical depiction of the training injection, enabling visualization of the injection from perspectives unavailable in the physical world. The training injection execution, as reflected in the measured sensor-based data, can be reviewed and analyzed at times after, and in locations different than, the time and location of the training injection. Additionally, injection training data associated with multiple training injections can be aggregated and analyzed for, among other things, trends in performance.Type: ApplicationFiled: May 14, 2018Publication date: September 13, 2018Inventors: Gabrielle A. Rios, David J. Mishelevich, Clark B. Foster
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Publication number: 20180261125Abstract: Systems and methods are disclosed for an apparatus and method for practicing injection techniques through an injectable apparatus. The injectable apparatus may contain a camera that is configured to detect the intensity and color of light attenuated from a testing tool after it is injected into a simulated human or animal body parts. A training tool may be connected to a user display device to generate a display of the injection apparatus as well as the performance parameters of a trainee.Type: ApplicationFiled: May 11, 2018Publication date: September 13, 2018Inventors: Gabrielle A. Rios, Jeff Crockett, Clark B. Foster, Milan Trcka, David J. Mishelevich, Aaron J. Gifford, Chris C. Ludolph
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Patent number: 10052497Abstract: Stimulation of target cells using light, e.g., in vivo, is implemented using a variety of methods and devices. In one example, embodiments involve methods for stimulating target cells using a photosensitive protein that allows the target cells to be stimulated in response to light. In another specific example embodiment, target cells are stimulated using an implantable arrangement. The arrangement includes an electrical light-generation means for generating light and a biological portion. The biological portion has a photosensitive bio-molecular arrangement that responds to the generated light by stimulating target cells in vivo. Other aspects and embodiments are directed to systems and methods for screening chemicals based screening chemicals to identify their effects on cell membrane ion channels and pumps, and to systems and methods for controlling an action potential of neuron (e.g., in in vivo and in vitro environments).Type: GrantFiled: January 9, 2008Date of Patent: August 21, 2018Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Karl Deisseroth, Feng Zhang, David J. Mishelevich, M. Bret Schneider
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Publication number: 20170246481Abstract: Disclosed are methods and systems for optimized deep or superficial deep-brain stimulation using multiple therapeutic modalities impacting one or multiple points in a neural circuit to produce Long-Term Potentiation (LTP) or Long-Term Depression (LTD). Also disclosed are methods for treatment of clinical conditions and obtaining physiological impacts.Type: ApplicationFiled: February 27, 2017Publication date: August 31, 2017Inventor: David J Mishelevich
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Publication number: 20170232177Abstract: The specification discloses a portable dialysis machine having a detachable controller unit and base unit. The controller unit includes a door having an interior face, a housing with a panel, where the housing and panel define a recessed region configured to receive the interior face of the door, and a manifold receiver fixedly attached to the panel. The base unit has a planar surface for receiving a container of fluid, a scale integrated with the planar surface, a heater in thermal communication with the planar surface, and a sodium sensor in electromagnetic communication with the planar surface. Embodiments of the disclosed portable dialysis system have improved structural and functional features, including improved modularity, ease of use, and safety features.Type: ApplicationFiled: November 2, 2016Publication date: August 17, 2017Inventors: Barry Neil Fulkerson, James Roswell Braig, David J Mishelevich, Charles Clemens, Clark Berg Foster, Martin Hering, Jan Brian Zwierstra, Russell Thomas Joseph, Victor Gura, Thomas Robinson, Milan Trcka, Daniele Ghidoli, Frank Isackson, Mark Forrest Smith
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Publication number: 20170186339Abstract: Systems and methods are disclosed for an apparatus and method for practicing injection techniques through an injectable apparatus. The injectable apparatus may contain a camera that is configured to detect the intensity and color of light attenuated from a testing tool after it is injected into a simulated human or animal body parts. A training tool may be connected to a user display device to generate a display of the injection apparatus as well as the performance parameters of a trainee.Type: ApplicationFiled: September 7, 2016Publication date: June 29, 2017Inventors: Gabrielle A. Rios, Jeff Crockett, Clark B. Foster, David J. Mishelevich, Milan Trcka, Aaron J. Gifford, Chris C. Ludolph
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Publication number: 20170151443Abstract: Described herein are shaped coil TMS electromagnets formed by two bent magnetic coil loops joined at a vertex having an angle between the outer coil regions of the coils that is typically less than 120 degrees (e.g., between about 45 and about 70 degrees, 60 degrees, etc.). The vertex region shaped to optimize the magnetic field projected from the TMS electromagnet. For example, the vertex region may be horizontal or vertical. In some variations the vertex region is formed by re-arranging the conductive windings forming the two coils so that they are no longer arranged in the same columnar structure that they are in the other portions of the bent magnetic coil loops. These TMS electromagnets may be well suited for use in deep-brain Transcranial Magnetic Stimulation.Type: ApplicationFiled: July 5, 2016Publication date: June 1, 2017Inventors: David J. MISHELEVICH, M. Bret SCHNEIDER
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Patent number: 9517296Abstract: The specification discloses a portable dialysis machine having a detachable controller unit and base unit. The controller unit includes a door having an interior face, a housing with a panel, where the housing and panel define a recessed region configured to receive the interior face of the door, and a manifold receiver fixedly attached to the panel. The base unit has a planar surface for receiving a container of fluid, a scale integrated with the planar surface, a heater in thermal communication with the planar surface, and a sodium sensor in electromagnetic communication with the planar surface. Embodiments of the disclosed portable dialysis system have improved structural and functional features, including improved modularity, ease of use, and safety features.Type: GrantFiled: September 27, 2013Date of Patent: December 13, 2016Assignee: Fresenius Medical Care Holdings, Inc.Inventors: Barry Neil Fulkerson, James Roswell Braig, David J Mishelevich, Charles Clemens, Clark Berg Foster, Martin Hering, Jan Brian Zwierstra, Russell Thomas Joseph, Victor Gura, Thomas Robinson, Milan Trcka, Daniele Ghidoli, Frank Isackson, Mark Forrest Smith
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Publication number: 20160346610Abstract: A system and method for optimizing a patient's Kegel exercises is provided. The system includes a user interface device and a vaginal device. The vaginal device includes an intra-vaginal probe having an accelerometer that is configured to generate a signal in response to movement of the probe. The user interface device is connected to the vaginal device and analyzes signals from the accelerometer to provide physiological feedback information to the patient. The vaginal device may be connected to the user interface device via wireless communications such as Bluetooth or by wire. The user interface device may be a smart device or a computer that transmits information to central web-based data server accessible by the patient or authorized healthcare providers or third-party payers.Type: ApplicationFiled: January 6, 2015Publication date: December 1, 2016Applicant: Remendium Labs LLCInventors: Ramon Jose Iglesias, David J. Mishelevich, Sean C. Nash, Kaitlin B. Schaefer, Jahnavi Lokre, Milan V. Trcka, Himanshu Patel, Jan B. Zwierstra, Trevor Dunlop, Aaron Gifford
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Patent number: 9486639Abstract: The present invention provides for Stereotactic Transcranial Magnetic Stimulation (sTMS) at predetermined locations with the brain or spinal cord and incorporates an array of electromagnets arranged in a specified configuration where selected coils in the array are pulsed simultaneously. Activation of foci demonstrated by functional MRI or other imaging techniques can be used to locate the neural region affected. Imaging techniques can also be utilized to determine the location of the designated targets.Type: GrantFiled: September 22, 2011Date of Patent: November 8, 2016Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: David J. Mishelevich, M. Bret Schneider
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Patent number: 9445742Abstract: A device is described for measuring electrical characteristics of biological tissues with plurality of electrodes and a processor controlling the stimulation and measurement in order to detect the presence of abnormal tissue masses in organs. Examples of suitable organs are the breast, skin, oral cavity, lung, liver, colon, rectum, cervix, and prostate and determine probability of tumors containing malignant cancer cells being present in tissue. The approach can also be applied to biopsied tissue samples. The device has the capability of providing the location of the abnormality. The method for measuring electrical characteristics includes placing electrodes and applying a voltage waveform in conjunction with a current detector. A mathematical analysis method is then applied to the collected data, which computes spectrum of frequencies and correlates magnitudes and phases with given algebraic conditions to determine mass presence and type.Type: GrantFiled: May 22, 2015Date of Patent: September 20, 2016Inventors: Roman A. Slizynski, David J. Mishelevich
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Patent number: 9443446Abstract: Systems and methods are disclosed for an apparatus and method for practicing injection techniques through an injectable apparatus. The injectable apparatus may contain a camera that is configured to detect the intensity and color of light attenuated from a testing tool after it is injected into a simulated human or animal body parts. A training tool may be connected to a user display device to generate a display of the injection apparatus as well as the performance parameters of a trainee.Type: GrantFiled: January 13, 2015Date of Patent: September 13, 2016Assignee: Trulnject Medical Corp.Inventors: Gabrielle A. Rios, Jeff Crockett, Clark B. Foster, David J. Mishelevich, Milan Trcka, Aaron J. Gifford, Chris C. Ludolph
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Publication number: 20160220274Abstract: External fixation assemblies offer good benefits in relevant orthopedic procedures but would be used more efficiently if the quick-release fasteners could be used so no tools would be required. This invention covers various embodiments of quarter-turn, quick-release fasteners, various shapes and surfaces of connecting rods and bone pins or other clamped objects to facilitate use of external fixation assemblies. Included are quick-release fasteners constructed from programmable magnets. Connecting rods can have fastening positions in the form of threaded or non-threaded holes. Both holes and connecting rods and bone pins can be of different shapes, for example, round, square, oval, pentagonal, hexagonal, octagonal, or any arbitrary shape. In both adding holes and non-circular shapes, rotation is eliminated allowing better fixation, and, in the case of holes or dimpled or out-dented surfaces, longitudinal motion along the rod or pin as well.Type: ApplicationFiled: March 27, 2016Publication date: August 4, 2016Inventors: Charles H. Lang, JR., David J. Mishelevich, Kevin Scott
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Patent number: 9386937Abstract: A device is described for measuring electrical characteristics of biological tissues with plurality of electrodes and a processor controlling the stimulation and measurement in order to detect the presence of abnormal tissue masses in organs. Examples of suitable organs are the breast, skin, oral cavity, lung, liver, colon, rectum, cervix, and prostate and determine probability of tumors containing malignant cancer cells being present in tissue. The approach can also be applied to biopsied tissue samples. The device has the capability of providing the location of the abnormality. The method for measuring electrical characteristics includes placing electrodes and applying a voltage waveform in conjunction with a current detector. A mathematical analysis method is then applied to the collected data, which computes spectrum of frequencies and correlates magnitudes and phases with given algebraic conditions to determine mass presence and type.Type: GrantFiled: May 17, 2015Date of Patent: July 12, 2016Inventors: Roman A. Slizynski, David J. Mishelevich
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Patent number: 9381374Abstract: Described herein are shaped coil TMS electromagnets formed by two bent magnetic coil loops joined at a vertex having an angle between the outer coil regions of the coils that is typically less than 120 degrees (e.g., between about 45 and about 70 degrees, 60 degrees, etc.). The vertex region shaped to optimize the magnetic field projected from the TMS electromagnet. For example, the vertex region may be horizontal or vertical. In some variations the vertex region is formed by re-arranging the conductive windings forming the two coils so that they are no longer arranged in the same columnar structure that they are in the other portions of the bent magnetic coil loops. These TMS electromagnets may be well suited for use in deep-brain Transcranial Magnetic Stimulation.Type: GrantFiled: September 14, 2015Date of Patent: July 5, 2016Assignee: Rio Grande Neurosciences, Inc.Inventors: David J. Mishelevich, M. Bret Schneider
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Publication number: 20160067518Abstract: Described herein are shaped coil TMS electromagnets formed by two bent magnetic coil loops joined at a vertex having an angle between the outer coil regions of the coils that is typically less than 120 degrees (e.g., between about 45 and about 70 degrees, 60 degrees, etc.). The vertex region shaped to optimize the magnetic field projected from the TMS electromagnet. For example, the vertex region may be horizontal or vertical. In some variations the vertex region is formed by re-arranging the conductive windings forming the two coils so that they are no longer arranged in the same columnar structure that they are in the other portions of the bent magnetic coil loops. These TMS electromagnets may be well suited for use in deep-brain Transcranial Magnetic Stimulation.Type: ApplicationFiled: September 14, 2015Publication date: March 10, 2016Inventors: David J. MISHELEVICH, M. Bret SCHNEIDER
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Publication number: 20160067516Abstract: Described herein are methods for neuromodulating brain activity of one or more target brain regions, the methods using Transcranial Magnetic Stimulation (TMS) to produce robust analgesia. In particular, described herein are systems for arranging one or more (e.g., a plurality) of TMS electromagnets in a configuration and applying sufficient energy to neuromodulate the dorsal anterior cingulate gyrus relative to cortical brain regions to significant modulate pain, including the pain of fibromyalgia.Type: ApplicationFiled: September 11, 2015Publication date: March 10, 2016Inventors: M. Bret SCHNEIDER, David J. MISHELEVICH, John W. SADLER