Abstract: The present invention relates to the use of (5S)-{[2-(4-carboxyphenyl)ethyl][2-(2-{[3-chloro-4?-(trifluoromethyl)biphenyl-4-yl]methoxy}phenyl)ethyl]-amino}-5,6,7,8-tetrahydroquinoline-2-carboxylic acid of formula (I), prefer-ably in form of one of its salts or solvates or hydrates, preferably (5S)-{[2-(4-carboxyphenyl)ethyl][2-(2-{[3-chloro-4?-(trifluoromethyl)biphenyl-4-yl]methoxy}phenyl)ethyl]-amino}-5,6,7,8-tetrahydroquinoline-2-carboxylic acid in form of monohydrate (I) of formula (I-M-I) or (5S)-{[2-(4-carboxyphenyl)ethyl][2-(2-{[3-chloro-4?-(trifluoromethyl)biphenyl-4-yl]methoxy}phenyl)-ethyl]-amino}-5,6,7,8-tetrahydroquinoline-2-carboxylic acid inform of mono hydrate (II) of formula (I-M-II), in the inhalative treatment of cardiopulmonary and pulmonary disorders, such as pulmonary arterial hypertension (P AH), chronic thromboembolic pulmonary hypertension (CTEPH) and pulmonary hypertension (PH) associated with chronic lung disease (PH group 3) such as pulmonary hypertension in chronic obstructive pulmo

Abstract: A membrane desalination system includes a housing, an electrically conductive membrane disposed within the housing, wherein the electrically conductive membrane includes a porous support and an electrically conductive layer disposed on the porous support, and the electrically conductive layer includes nanostructures, and an alternating current power source connected to the electrically conductive membrane.

Abstract: An example sensor interposer employing castellated through-vias formed in a PCB includes a planar substrate defining a plurality of castellated through-vias; a first electrical contact formed on the planar substrate and electrically coupled to a first castellated through-via; a second electrical contact formed on the planar substrate and electrically coupled to a second castellated through-via, the second castellated through-via electrically isolated from the first castellated through-via; and a guard trace formed on the planar substrate, the guard trace having a first portion formed on a first surface of the planar substrate and electrically coupling a third castellated through-via to a fourth castellated through-via, the guard trace having a second portion formed on a second surface of the planar substrate and electrically coupling the third castellated through-via to the fourth castellated through-via, the guard trace formed between the first and second electrical contacts to provide electrical isolation b

Abstract: An improved shelving unit for a shipping container is disclosed herein. The improved shelving unit can comprise one or more shelf assemblies and an RFID reader. Each of the one or more shelf assemblies can comprise a bottom platform and a top platform. The RFID reader can be mounted between the bottom platform and the top platform. The top platform can be capable of supporting items.

Abstract: The present disclosure describes techniques for coding and decoding video in which a plurality of coding hypotheses are developed for an input pixel block of frame content. Each coding hypothesis may include generation of prediction data for the input pixel block according to a respective prediction search. The input pixel block may be coded with reference to a prediction block formed from prediction data derived according to plurality of hypotheses. Data of the coded pixel block may be transmitted to a decoder along with data identifying a number of the hypotheses used during the coding to a channel. At a decoder, an inverse process may be performed, which may include generation of a counterpart prediction block from prediction data derived according to the hypothesis identified with the coded pixel block data, then decoding of the coded pixel block according to the prediction data.

Abstract: Examples describe an egress port manager that uses an adaptive jitter selector to apply a jitter threshold level for a buffer, wherein the jitter threshold level is to indicate when egress of a packet segment from the buffer is allowed, wherein a packet segment comprises a packet header and wherein the jitter threshold level is adaptive based on a switch fabric load. In some examples, the jitter threshold level is to indicate a number of segments for the buffer's head of line (HOL) packet that are to be in the buffer or indicate a timer that starts at a time of issuance of a first read request for a first segment of the packet in the buffer. In some examples, the jitter threshold level is not more than a maximum transmission unit (MTU) size associated with the buffer.

Abstract: Systems and methods are disclosed for flexibly controlling laser pulses being output from a laser system. An example surgical system comprises a laser, an optical switching device, and a laser pulse controller. Optical switching control signals communicated by the laser pulse controller control the length of a pulse picking cycle and the number of laser pulses in each pulse picking cycle to be output from the laser system. The number of laser pulses in each pulse picking cycle to be output from the laser system may be adjustable in a range that includes more than 50% of the laser pulses in each pulse picking cycle.

Abstract: Systems and methods are disclosed for flexibly controlling laser pulses being output from a laser system. An example surgical system comprises a laser, a laser energy control system configured to regulate the amount of electromagnetic energy of each laser pulse that exits the laser system, and a laser pulse controller. The control signals communicated by the laser pulse controller may include a sub-carrier signal that modulates the amount of electromagnetic energy of the laser pulses that exit the laser system. The control signals may further include a threshold signal and/or a maximum power signal. The sub-carrier signal may oscillate between the threshold power and a maximum power.

Abstract: In some embodiments, a method receives a request for an interface. A configuration for the interface includes a plurality of slots that are associated with a plurality of collection pools, wherein each collection pool is configurable with a ranking strategy. The method determines a collection pool for a slot in the interface where the collection pool is associated with a plurality of collections. A collection is received for the slot. The collection is determined by ranking the plurality of collections using a ranking strategy for the collection pool to generate a ranking of the plurality of collections. The method outputs the collection for the collection pool for display in the slot of the interface.

Abstract: A filter holder for liposome extrusion includes a housing having an inlet configured to receive a material to be extruded and an outlet, and a filter support member disposed within the housing between the inlet and the outlet. The filter support member includes an upstream side having a filter support surface configured to support a membrane filter assembly, a downstream side opposite the upstream side, and a plurality of passages extending through the filter support member from the filter support surface to the downstream side. The filter holder also includes an outlet cavity in fluid communication with the outlet, and the filter holder is configured such that the material to be extruded flows through the membrane filter assembly and into the outlet cavity via the plurality of passages before being discharged through the outlet.

Abstract: Systems and methods are disclosed for dynamically controlling laser pulses being output from a laser system. An example surgical system comprises a laser, an optical switching device, an adjustable input device such as a foot pedal, and a laser pulse controller. An operator actuates the adjustable input device over an operating range to control dynamically the laser pulses being output from the laser system. In one mode, the adjustable input device may dynamically control output laser energy. In another mode, the adjustable input device may dynamically control selection of laser pulses to be output from the system.

Abstract: In some embodiments, a method receives a request for an interface. A configuration for the interface includes a plurality of slots that are associated with a plurality of collection pools, wherein each collection pool is configurable with a ranking strategy. The method determines a collection pool for a slot in the interface where the collection pool is associated with a plurality of collections. A collection is received for the slot. The collection is determined by ranking the plurality of collections using a ranking strategy for the collection pool to generate a ranking of the plurality of collections. The method outputs the collection for the collection pool for display in the slot of the interface.

Abstract: An improved wall panel for an automated inventory module is disclosed herein. The improved wall panel can comprise a wall panel. The wall panel can be capable of being mounted at a corrugated interior surface of an automated inventory module (AIM). The wall panel can comprise a substantially flat first exterior layer comprising a first side and a second side. The first exterior layer first side can face the interior of the AIM when the wall panel is mounted at the interior surface, and the first exterior layer second side can face the interior surface when the wall panel is mounted at the interior surface. The first exterior layer can comprise a ferromagnetic material.

Abstract: An improved shelving unit for a shipping container is disclosed herein. The improved shelving unit can comprise one or more shelf assemblies and an RFID reader. Each of the one or more shelf assemblies can comprise a bottom platform and a top platform. The RFID reader can be mounted between the bottom platform and the top platform. The top platform can be capable of supporting items.

Abstract: An improved automated inventory system is herein disclosed. The improved automated system (AIS) can comprise an enclosure for storing one or more items, one or more RFID readers, and a control system. Each of the items are tagged with an RFID (radio frequency identification) tag. The enclosure can comprise a plurality of of interior surfaces that defines an interior space within said enclosure. The enclosure can also comprise one or more access points within the interior surfaces that allow access to the items within the enclosure. Each of the RFID readers can be capable of reading the RFID tag. The control system can be in communication with the one or more RFID readers.

Abstract: Systems and methods are disclosed for selectively allowing or preventing output of laser pulses. In some embodiments, a laser system comprises a shutter and a shutter motor. The shutter motor is configured to move the shutter in an alternating manner between a first position in which output of laser electromagnetic radiation is allowed a second position in which output of laser electromagnetic radiation is prevented.

Abstract: Systems and methods are disclosed for monitoring a laser system using detection of back reflection. In some embodiments, a laser system comprises a laser, at least one optical fiber, and a back-reflection monitoring sensor for detecting electromagnetic radiation reflected back from the optical fiber(s). The back-reflection monitoring sensor may be adapted to detect back-reflected electromagnetic radiation while the laser system is in use. The laser system may further comprise a computing system adapted to calculate an output power of the system based upon the back-reflected electromagnetic radiation. In some embodiments, a method of monitoring a laser system using detection of back reflection comprises transmitting electromagnetic radiation from a laser, receiving the electromagnetic radiation at one or more optical fibers, and detecting electromagnetic radiation that is back reflected at a back-reflection monitoring sensor.

Abstract: This invention relates to drug conjugates useful for localized treatment of diseases or disorders of the middle ear and/or inner ear. Methods of treating diseases or disorders of the middle ear and/or inner ear, pharmaceutical compositions comprising the conjugates, and methods of inhibiting a Tropomyosin receptor kinase are also provided.

Abstract: Methods and systems are provided for forming a molded foam article. An example method may include molding a plurality of separate pieces of closed-cell foam by exposure to a temperature cycle within a sealed mold to soften the plurality of pieces sufficiently for physical bonding; and forming a molded foam article with the pieces bonded together without an adhesive, wherein, during the temperature cycle, the mold is unsealed at least once to release gases and/or pressure. In another example, a method includes exposing a filled, sealed mold filled with a plurality of pieces of foamed material to a heating cycle; at a threshold temperature, unsealing the filled, sealed mold until a pressure reduces to within a threshold of atmospheric pressure; and, following the unsealing, cooling the filled mold prior to removing a molded foam article.

Abstract: Systems and methods are disclosed for controlled illumination of LEDs. An example system comprises: a plurality of LEDs; an LED controller; a current buffer adapted to receive an input bias level signal from the LED controller, wherein a set of LEDs to be controlled together are connected in parallel with each other in a circuit with the current buffer; and at least one current limiting resistor connected in the circuit with the plurality of LEDs and the current buffer. The systems and methods are adapted to control the illumination of the LEDs by applying a constant voltage to the circuit based upon the input bias level signal, thereby controlling the illumination of the light-emitting diodes without the use of pulse width modulation. Crosstalk interference with RFID components due to pulse width modulation is thereby avoided.