Abstract: An orthopedic plate is specifically configured for use in osteotomies, in which part of the plate extends into a portion of a first bone segment and part is external to the cortical surface of an adjacent bone segment to fix the segments to allow them to fuse. The plate has a first end and a second end where the end which is inserted into the bone has a chamfer and a through hole having a hole axis optionally at an oblique angle to the longitudinal axis of the plate, and which can receive a screw, peg or pin. The second end of the plate includes a locking screw hole and optionally including a compression slot extending in a direction toward a screw hole in the opposing end. Optionally, the non-locking hole has a shroud that forms an arc or portion of a cylinder over the hole. A plate driver having a recess that holds the plate is used to insert the plate into the bone.

Abstract: The present invention relates to compounds useful as inhibitors of ATR protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and methods of using the compounds in in vitro applications, such as the study of kinases in biological and pathological phenomena; the study of intracellular signal transduction pathways mediated by such kinases; and the comparative evaluation of new kinase inhibitors. The compounds of this invention have formula I: or a pharmaceutically acceptable salt, wherein the variables are as devined herein. Moreover, The compounds of this invention have formula I-A: or a pharmaceutically acceptable salt, wherein the variables are as defined herein.

Abstract: A head up display arrangement for a motor vehicle includes a head up display projector including a lens with a polarizer. The head up display projector emits a linearly polarized light field via the lens. A windshield reflects the light field such that the reflected light field is visible to a human driver of the motor vehicle as a virtual image. The windshield includes an outer plastic layer sandwiched between a half-wave plate and an outer glass layer. An inner plastic layer is sandwiched between the half-wave plate and an inner glass layer.

Abstract: A motor vehicle includes a head up display projector producing a light field such that the light field is reflected off of a windshield of the motor vehicle and is then visible to a driver of the motor vehicle as a virtual image. A sensor measures an effect of vibration on the motor vehicle and transmits a sensor signal dependent upon the measured effect. An actuator is coupled to the head up display projector and moves a component of the head up display projector such that a position and/or orientation of the virtual image as perceived by the driver is changed. An electronic processor is communicatively coupled to each of the head up display projector, the sensor and the actuator. The electronic processor receives the sensor signal and controls the actuator dependent upon the sensor signal such that the virtual image appears to be unaffected by the vibration.

Abstract: A motor vehicle includes a head up display projector emitting a light field. A windshield includes an outer layer of glass, an inner layer of glass, and a plastic layer sandwiched between the outer layer of glass and the inner layer of glass. The light field is reflected toward eyes of a driver of the motor vehicle by a reflective material added to one of an inner surface of the plastic layer, an outer surface of the plastic layer, an inner surface of the outer layer of glass, and an outer surface of the inner layer of glass.

Abstract: A motor vehicle includes a head up display projector producing a light field based upon image data such that the light field is reflected off of a windshield of the motor vehicle and is then visible to a driver of the motor vehicle as a virtual image. First means determines locations of physical objects visible to the driver through the windshield. Second means determines locations of eyes of the driver. An electronic processor receives first data indicative of the determined locations of the physical objects, and receives second data indicative of the determined locations of the eyes of the driver. The electronic processor produces the image data dependent upon the first data and the second data such that a symbol in the virtual image appears to be in a predetermined position relative to a selected one of the physical objects.

Abstract: The present invention relates to compounds useful as inhibitors of ATR protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and methods of using the compounds in in vitro applications, such as the study of kinases in biological and pathological phenomena; the study of intracellular signal transduction pathways mediated by such kinases; and the comparative evaluation of new kinase inhibitors. The compounds of this invention have formula I: or a pharmaceutically acceptable salt, wherein the variables are as devined herein. Moreover, The compounds of this invention have formula I-A: or a pharmaceutically acceptable salt, wherein the variables are as defined herein.

Abstract: An orthopedic plate is specifically configured for use in osteotomies, in which part of the plate extends into a portion of a first bone segment and part is external to the cortical surface of an adjacent bone segment to fix the segments to allow them to fuse. The plate has a first end and a second end where the end which is inserted into the bone has a chamfer and a through hole having a hole axis optionally at an oblique angle to the longitudinal axis of the plate, and which can receive a screw, peg or pin. The second end of the plate includes a locking screw hole and optionally including a compression slot extending in a direction toward a screw hole in the opposing end. Optionally, the non-locking hole has a shroud that forms an arc or portion of a cylinder over the hole. A plate driver having a recess that holds the plate is used to insert the plate into the bone.

Abstract: A head up display arrangement for a motor vehicle includes an image source emitting a light field. A first freeform mirror is positioned to provide a first reflection of the light field. A generally concave second freeform mirror is positioned to receive the first reflection and provide a second reflection of the light field. The second reflection is reflected off of a windshield of the vehicle so as to be visible to a driver of the vehicle. An arcuate section of a surface of the generally concave second freeform mirror receives the first reflection and provides the second reflection. An angle between the first freeform mirror and an imaginary line that is tangent to a midpoint of the arcuate section of the surface of the generally concave second freeform mirror is approximately between thirty degrees and sixty degrees.

Abstract: A multi-sensory sensor comprises at least a first and a second sensor element, wherein the multi-sensory sensor is adapted for attachment to a movable structure in a building. The multi-sensory sensor is operatively associated with a controller that is configured to receive input from said first sensor element, wherein the input is indicative of a movement of the movable structure. The controller is further configured to receive input from the second sensor element, and indirectly identify a human behavioural action in the building based on a combination of the input from the first sensor element and the input from the second sensor element. It is further configured to determine a function to be taken based on the identified action, and cause the function to be taken to be executed. In one embodiment the first sensor is a movement sensor element for sensing a movement and the second sensor element is an audio sensor element for sensing audio.

Abstract: Drop-weight tower (110) for reproducibly initiating a crack in a material sample for fracture mechanics testing comprising a base (120) with a top surface upon which a sample holder (124) is mounted to grip a material sample, an attachment column (140) having a linear rail (142), a carriage (162) attached to the linear rail (142) and a stage (164) is attached to the carriage. The stage (164) includes a vertical rod (184) and a razor-blade holder (178). A weight is slidably mounted to the vertical rod (184). The carriage is used to adjust the height of the stage (164) relative to the material sample. A hammer (180) slides up and down the vertical rod (184) to apply consistent and reproducible force on the razor (178) that then initiates the crack in the material sample.

Abstract: A head up display arrangement for a motor vehicle includes an image source emitting a virtual image based on image data. A mirror is positioned to reflect the virtual image such that the virtual image further reflects off of a windshield of the motor vehicle and is visible to a driver of the vehicle while eyes of the driver are disposed within an eyebox. A driver's input device is coupled to the mirror and changes an angle of reflection of the mirror and thereby changes a vertical level of the eyebox in response to input from the driver. A controller is communicatively coupled to the image source and produces the image data. The controller determines the angle of reflection of the mirror, and adjusts the image data in response to the change in the angle of reflection of the mirror such that a vertical level of the virtual image is unchanged by the change in the angle of reflection of the mirror.

Abstract: Systems and methods are described herein for performing actions based on a determined intent within messages received by a mobile device. In some embodiments, the systems and methods may access a message received by a mobile application (e.g., text messaging application, chat application, and so on) of the mobile device, analyze the message to determine an intent of the message (e.g., whether the message includes a request or a task for a recipient of the message), and perform an action based on the determined intent (e.g., set a reminder when the message includes a task for the recipient). Further details are described herein.

Abstract: Systems and methods are described herein for determining suggestions of emojis, and other pictorial or multimedia elements, to users based on the content (e.g., a derived intent, tone, sentiment, and so on) of their messages. In some embodiments, the systems and methods access a string of text input by a user of a messaging application of a computing device, assign a specific classification to the string of text, and identify one or more pictorial elements to present to the user for insertion into the string of text that are associated with the specific classification of the string of text.

Abstract: A multi-sensory sensor comprises at least a first and a second sensor element, wherein the multi-sensory sensor is adapted for attachment to a movable structure in a building. The multi-sensory sensor is operatively associated with a controller that is configured to receive input from said first sensor element, wherein the input is indicative of a movement of the movable structure. The controller is further configured to receive input from the second sensor element, and indirectly identify a human behavioral action in the building based on a combination of the input from the first sensor element and the input from the second sensor element. It is further configured to determine a function to be taken based on the identified action, and cause the function to be taken to be executed. In one embodiment the first sensor is a movement sensor element for sensing a movement and the second sensor element is an audio sensor element for sensing audio.

Abstract: A head up display arrangement for a motor vehicle includes an image source providing an illuminated image. A first concave mirror is positioned to provide a first reflection of the illuminated image. A second concave mirror is positioned to receive the first reflection and provide a second reflection of the illuminated image. A windshield is positioned to receive the second reflection and provide a third reflection of the illuminated image such that the third reflection is visible to a driver of the vehicle.

Abstract: A head up display arrangement for a motor vehicle includes a disc having a plurality of holographic optical elements. A motor rotates the disc. An image source produces an image. A transmissive display receives the image and collimated coherent light and projects an illuminated version of the image onto the disc. An optical element receives a reflection of the illuminated version of the image off of the disc and projects the reflection onto a windshield of the motor vehicle.

Abstract: A head up display arrangement for a motor vehicle includes a body that is at least partially transparent and that has a plurality of outer surfaces. An image source emits an illuminated image into a transparent portion of the body such that the illuminated image is internally reflected off the outer surfaces a plurality of times within the transparent portion of the body before leaving the body and then being reflected off of a windshield of the vehicle such that the illuminated image is visible to a driver of the vehicle.

Abstract: The present invention relates to compounds useful as inhibitors of ATR protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and methods of using the compounds in in vitro applications, such as the study of kinases in biological and pathological phenomena; the study of intracellular signal transduction pathways mediated by such kinases; and the comparative evaluation of new kinase inhibitors. The compounds of this invention have formula I: or a pharmaceutically acceptable salt, wherein the variables are as devined herein. Moreover, The compounds of this invention have formula I-A: or a pharmaceutically acceptable salt, wherein the variables are as defined herein.

Abstract: The present invention relates to pyrazine compounds useful as inhibitors of ATR protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and methods of using the compounds in in vitro applications, such as the study of kinases in biological and pathological phenomena; the study of intracellular signal transduction pathways mediated by such kinases; and the comparative evaluation of new kinase inhibitors. Certain compounds of this invention are of formula II, V, and/or VII: wherein the variables are as defined herein.