Abstract: A window function generating system is presented herein. The system includes a first node; a second node; an integrator portion coupled to the first node; a differentiator portion coupled to the second node; and a rate adjustor coupled to the integrator portion and to the differentiator portion. The system also includes a multiplier configured to receive an input signal from the input node and a window function signal from the second node and to produce an output signal based on the input signal and window function signal.

Abstract: A system for determining one or more coefficients of a filter is presented. The system includes a modulated ramp generator including a ramp generator, a delta-sigma modulator coupled to the ramp generator and configured to generate a control signal, and a control output coupled to the delta-sigma modulator and configured to receive the control signal; and a filter coupled to the control output and configured to receive the control signal from the control output, the filter including one or more configurable coefficients, values of the configurable coefficients being selected by the control signal, an input for receiving a filterable signal, and an output for providing a filtered signal.

Abstract: Aspects of this disclosure relate to an asynchronous sample rate converter (ASRC) comprising a signal input configured to receive an input signal having one or more input signal values at a first sample rate, a first clock input configured to receive an input clock signal corresponding to the first sample rate, a signal output configured to provide an output signal having one or more output signal values at a second sample rate, a second clock input configured to receive an output clock signal corresponding to the second sample rate, a zero-padding circuit configured to add a plurality of zero values following at least one of the one or more input signal values, and a filter configured to generate the output signal, the output signal having one or more output signal values based on the input signal.

Abstract: A method for calibrating an audio amplification system can include injecting a tone having a frequency to an input path of an audio amplifier, such that an input signal provided to the audio amplifier includes the tone signal. The method can further include sampling an output signal at an output node of the audio amplifier, and sampling the input signal at an input node of the audio amplifier. The method can further include generating a correction signal based on the sampled output signal and the sampled input signal to correct for a gain variation of the audio amplifier.

Abstract: Various devices and methods are provided for machine learning-driven medical diagnostic testing. In one example, a method includes generating a patient-specific collaboration channel comprising a patient-specific dashboard and a communication thread between a care provider team monitoring a patient and a virtual healthcare assistant, storing, at the channel, text- and/or rich media-based messages on the communication thread between one or more care providers of the care provider team and the virtual healthcare assistant, at least a portion of the messages on the communication thread including patient-specific medical data, and responsive to a prompt, outputting at least a portion of the communication thread that includes the patient-specific medical data to a display device.

Abstract: In some embodiments, a calibration circuit for an audio amplification system can include a tone generator configured to provide a tone having a frequency to an input path of an audio amplifier, such that an input signal provided to the audio amplifier includes the tone, a a first sampling circuit configured to sample an output signal at an output node of the audio amplifier, and a second sampling circuit configured to sample the input signal at an input node of the audio amplifier. The calibration circuit can further include a gain adjustment circuit configured to generate a correction signal based on the sampled output signal and the sampled input signal to correct for a gain variation of the audio amplifier.

Abstract: This disclosure relates generally to a system for mitigating error in an amplifier. The system may include a loop filter; a driver; a digital-to-analog converter (DAC) configured to source and to sink current; an edge selector configured to determine a first delay between the driver receiving a signal to provide a driver output signal and the driver providing the driver output signal; a timing circuit configured to determine a second delay between the DAC receiving a signal to provide a DAC output current and the DAC providing the DAC output current; and at least one controller configured to control the DAC to source or to sink the DAC output current at a time corresponding to a beginning of the driver output signal, and control the DAC to stop sourcing or sinking the DAC output current at a time corresponding to an end of the driver output signal.

Abstract: Aspects of this disclosure relate to an asynchronous sample rate converter (ASRC) comprising a signal input configured to receive an input signal having one or more input signal values at a first sample rate, a first clock input configured to receive an input clock signal corresponding to the first sample rate, a signal output configured to provide an output signal having one or more output signal values at a second sample rate, a second clock input configured to receive an output clock signal corresponding to the second sample rate, a zero-padding circuit configured to add a plurality of zero values following at least one of the one or more input signal values, and a filter configured to generate the output signal, the output signal having one or more output signal values based on the input signal.

Abstract: In some embodiments, a calibration circuit for an audio amplification system can include a tone generator configured to provide a tone having a frequency to an input path of an audio amplifier, such that an input signal provided to the audio amplifier includes the tone, a a first sampling circuit configured to sample an output signal at an output node of the audio amplifier, and a second sampling circuit configured to sample the input signal at an input node of the audio amplifier. The calibration circuit can further include a gain adjustment circuit configured to generate a correction signal based on the sampled output signal and the sampled input signal to correct for a gain variation of the audio amplifier.

Abstract: The present invention provides methods for treating, preventing or ameliorating a fibrotic condition. The methods of the present invention include administering to a patient suffering from a fibrotic condition a therapeutically effective amount an anti-interleukin-36 receptor (anti-IL-36R) antibody.

Abstract: Various devices and methods are provided for machine learning-driven medical diagnostic testing. In one example, a method includes generating a patient-specific collaboration channel comprising a patient-specific dashboard and a communication thread between a care provider team monitoring a patient and a virtual healthcare assistant, storing, at the channel, text- and/or rich media-based messages on the communication thread between one or more care providers of the care provider team and the virtual healthcare assistant, at least a portion of the messages on the communication thread including patient-specific medical data, and responsive to a prompt, outputting at least a portion of the communication thread that includes the patient-specific medical data to a display device.

Abstract: Various devices and methods are provided for machine learning-driven medical diagnostic testing. In one example, a method includes generating a patient-specific collaboration channel comprising a patient-specific dashboard and a communication thread between a care provider team monitoring a patient and a virtual healthcare assistant, storing, at the channel, text- and/or rich media-based messages on the communication thread between one or more care providers of the care provider team and the virtual healthcare assistant, at least a portion of the messages on the communication thread including patient-specific medical data, and responsive to a prompt, outputting at least a portion of the communication thread that includes the patient-specific medical data to a display device.

Abstract: A variable output data rate converter circuit preferably meets performance requirements while keeping the circuit complexity low. In some embodiments, the converter circuit may include an oversampling sigma delta modulator circuit to quantize an analog input signal at an oversampled rate, and output an sigma delta modulated signal, a transposed polynomial decimator circuit to decimate the sigma delta modulated signal, and output a first decimated signal, and an integer decimator circuit to decimate the first decimated signal by an integer factor and output a second decimated signal having a desired output data rate. The transposed polynomial decimator circuit has a transposed polynomial filter circuit and a digital phase locked loop circuit, which tracks a ratio between a sampling rate of the first decimated signal and the oversampled rate, and outputs an intersample position parameter to the transposed polynomial filter circuit.

Abstract: A variable output data rate converter circuit preferably meets performance requirements while keeping the circuit complexity low. In some embodiments, the converter circuit may include an oversampling sigma delta modulator circuit to quantize an analog input signal at an oversampled rate, and output an sigma delta modulated signal, a transposed polynomial decimator circuit to decimate the sigma delta modulated signal, and output a first decimated signal, and an integer decimator circuit to decimate the first decimated signal by an integer factor and output a second decimated signal having a desired output data rate. The transposed polynomial decimator circuit has a transposed polynomial filter circuit and a digital phase locked loop circuit, which tracks a ratio between a sampling rate of the first decimated signal and the oversampled rate, and outputs an intersample position parameter to the transposed polynomial filter circuit.

Abstract: Various devices and methods are provided for machine learning-driven medical diagnostic testing. In one example, a method includes generating a patient-specific collaboration channel comprising a patient-specific dashboard and a communication thread between a care provider team monitoring a patient and a virtual healthcare assistant, storing, at the channel, text- and/or rich media-based messages on the communication thread between one or more care providers of the care provider team and the virtual healthcare assistant, at least a portion of the messages on the communication thread including patient-specific medical data, and responsive to a prompt, outputting at least a portion of the communication thread that includes the patient-specific medical data to a display device.

Abstract: In a cascaded integrator comb (CIC) filter, a time-varying gain is added before the last integrating stage transforming its sub optimal boxcar impulse response into an FIR filter of arbitrary length. Make the coefficients sparse and taking them from a set of small integers leads to an efficient hardware implementation that does not compromise any of the essential CIC filter characteristics especially the overflow handling. The proposed sparse CIC structure can improve the worst case stop band attenuation by as much as 10 dB while occupying 77% of the chip area and consuming 30% less power compared to a standard a 5th order CIC filter, and reducing the overall bit growth of the filter and the amount of high rate operations. Design examples are given illustrating the advantages and flexibility of the proposed structure.

Abstract: In a cascaded integrator comb (CIC) filter, a time-varying gain is added before the last integrating stage transforming its sub optimal boxcar impulse response into an FIR filter of arbitrary length. Make the coefficients sparse and taking them from a set of small integers leads to an efficient hardware implementation that does not compromise any of the essential CIC filter characteristics especially the overflow handling. The proposed sparse CIC structure can improve the worst case stop band attenuation by as much as 10 dB while occupying 77% of the chip area and consuming 30% less power compared to a standard a 5th order CIC filter, and reducing the overall bit growth of the filter and the amount of high rate operations. Design examples are given illustrating the advantages and flexibility of the proposed structure.

Abstract: A discrete-time (e.g., digital) filter can be used as an interpolation filter for processing an oversampled input signal, such as included as a portion of a sigma-delta digital-to-analog conversion circuit. An interpolation filter control circuit can be configured to adjust a filter order of the discrete-time interpolation filter at least in part in response to information indicative of an envelope signal magnitude. For example, higher-level input signals might be processed using an interpolation filter having a stop-band attenuation that is more stringently-specified (e.g., having greater attenuation) than a corresponding attenuation used for lower-level input signals. The filter order can be variable, such as varied in response to a detected envelope magnitude of the input signal to achieve power savings as compared to a filter having fixed parameters.

Abstract: A method for immobilizing dyes and antimicrobial agents on a polymeric cover or housing for a medical device is disclosed and described. The surface may be that of a catheter, a connector, a drug vial spike, a bag spike, a prosthetic device, an endoscope, a surface of an infusion pump, a key pad, a touch screen or a handle. The surfaces may also be one or more of those associated with a infusion of a medicament or dialysis treatment, such as peritoneal dialysis or hemodialysis, where it is important that the working surface for the dialysis fluid be sterile. These surfaces include connectors for peritoneal dialysis sets or for hemodialysis sets, bag spikes, dialysis catheters, and so forth. A method for determining whether a surface has been sterilized, and a dye useful in so indicating, is also disclosed.

Abstract: A method for immobilizing dyes and antimicrobial agents on a polymeric cover or housing for a medical device is disclosed and described. The surface may be that of a catheter, a connector, a drug vial spike, a bag spike, a prosthetic device, an endoscope, a surface of an infusion pump, a key pad, a touch screen or a handle. The surfaces may also be one or more of those associated with a infusion of a medicament or dialysis treatment, such as peritoneal dialysis or hemodialysis, where it is important that the working surface for the dialysis fluid be sterile. These surfaces include connectors for peritoneal dialysis sets or for hemodialysis sets, bag spikes, dialysis catheters, and so forth. A method for determining whether a surface has been sterilized, and a dye useful in so indicating, is also disclosed.