Patents by Inventor David Marks

David Marks has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180350169
    Abstract: A method and a device for monitoring the functioning of a crankcase ventilation system of an internal combustion engine, crankcase ventilation gas being supplied to an intake line of the internal combustion engine via at least one crankcase ventilation line from the crankcase via an oil separator and a crankcase pressure regulating valve. An immediate surrounding environment of the internal combustion engine is monitored by at least one sensor that is sensitive to crankcase ventilation gas or to at least one crankcase ventilation gas component for the occurrence of crankcase ventilation gas, and that, if a presence of crankcase ventilation gas is determined, an informative or warning message is produced.
    Type: Application
    Filed: June 6, 2017
    Publication date: December 6, 2018
    Inventors: Stephan AHLBORN, David Mark POLLOCK
  • Patent number: 10140878
    Abstract: There is provided systems and methods for pilot alertness and awareness of target aircraft and target obstacle that are flying within a proceeding flight path collision. Transmitted guiding sound signals consisting of three dimensional effects and tonal sounds are generated by a flight unit, and sent to the pilot's headset for the desired purpose of directing the pilot's head position to locate the target aircraft and target obstacle. The flight unit processes time of collision from received target aircraft broadcast, and contain at least GPS data and target obstacle information from stored navigational maps. The flight unit further receives the pilot's head position through means of a head tracker. Furthermore, the flight unit is able to perform the functions of, storing piloted flight information, voice language instruction, flight assisted notification, and communicating with one or multiple mobile devices such for the information to be displayed visually, and is upgradable remotely.
    Type: Grant
    Filed: September 8, 2016
    Date of Patent: November 27, 2018
    Assignee: Beeper Avionics Inc.
    Inventors: Christopher Schupp, Jay David Marks
  • Publication number: 20180333400
    Abstract: The present application discloses a compound which is which activates Wnt/?-catenin signaling and thus treats or prevents diseases related to signal transduction, such as osteoporosis and osteoarthropathy; osteogenesis imperfecta, bone defects, bone fractures, periodontal disease, otosclerosis, wound healing, craniofacial defects, oncolytic bone disease, traumatic brain injuries related to the differentiation and development of the central nervous system, comprising Parkinson's disease, strokes, ischemic cerebral disease, epilepsy, Alzheimer's disease, depression, bipolar disorder, schizophrenia; eye diseases such as age related macular degeneration, diabetic macular edema or retinitis pigmentosa and diseases related to differentiation and growth of stem cell, comprising hair loss, hematopoiesis related diseases and tissue regeneration related diseases.
    Type: Application
    Filed: December 27, 2017
    Publication date: November 22, 2018
    Inventors: Sunil Kumar KC, David Mark Wallace, John Hood, Charlene F. Barroga
  • Patent number: 10131677
    Abstract: Azaindazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present invention concerns the use of an azaindazole compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, fibrotic disorders, bone or cartilage diseases, and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases and neurological conditions/disorders/diseases due to mutations or dysregulation of the Wnt pathway and/or of one or more of Wnt signaling components. Also provided are methods for treating Wnt-related disease states.
    Type: Grant
    Filed: August 4, 2017
    Date of Patent: November 20, 2018
    Assignee: Samumed, LLC
    Inventors: Sunil Kumar KC, David Mark Wallace, Jianguo Cao, Chandramouli Chiruta, John Hood
  • Publication number: 20180325910
    Abstract: Azaindazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present invention concerns the use of an azaindazole compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, fibrotic disorders, bone or cartilage diseases, and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases and neurological conditions/disorders/diseases due to mutations or dysregulation of the Wnt pathway and/or of one or more of Wnt signaling components. Also provided are methods for treating Wnt-related disease states.
    Type: Application
    Filed: December 15, 2017
    Publication date: November 15, 2018
    Inventors: Sunil Kumar KC, David Mark Wallace, Jianguo Cao, Chandramouli Chiruta, John Hood
  • Publication number: 20180318292
    Abstract: Indazole compounds for treating various diseases and pathologies are provided. More particularly, the use of an indazole compound or analogs thereof, in the treatment of inflammatory diseases or disorders is provided.
    Type: Application
    Filed: November 7, 2016
    Publication date: November 8, 2018
    Inventors: John Hood, David Mark Wallace, Sunil Kumar KC, Yusuf Yazici, Christopher Swearingen, Luis A Dellamary
  • Publication number: 20180314835
    Abstract: Anomaly detection in computing environments is disclosed herein. An example method includes receiving an unstructured input stream of data instances from the computing environment, the unstructured input stream being time stamped; categorizing the data instances of the unstructured input stream of data instances, the data instances comprising at least one principle value and a set of categorical attributes determined through machine learning; generating anomaly scores for each of the data instances collected over a period of time; and detecting a change in the categorical attribute that is indicative of an anomaly.
    Type: Application
    Filed: December 27, 2017
    Publication date: November 1, 2018
    Inventors: Stephen Dodson, Thomas Veasey, David Mark Roberts
  • Patent number: 10105370
    Abstract: Provided herein are compounds according to Formula I and pharmaceutically acceptable salts thereof, and compositions comprising the same, for use in various methods, including treating cancers such as colon, ovarian, pancreatic, breast, liver, prostate and hematologic cancers:
    Type: Grant
    Filed: November 14, 2017
    Date of Patent: October 23, 2018
    Assignee: Samumed, LLC
    Inventors: John Hood, Sunil Kumar KC, David Mark Wallace
  • Publication number: 20180298358
    Abstract: The invention relates to modified polymerase enzymes which exhibit improved incorporation of nucleotide analogues bearing substituents at the 3? position of the sugar moiety that are larger in size than the naturally occurring 3? hydroxyl group. Also described are methods of using the polymerases to incorporate nucleotides into polynucleotides, particularly in the context of DNA sequencing.
    Type: Application
    Filed: June 26, 2018
    Publication date: October 18, 2018
    Applicant: Illumina Cambridge Limited
    Inventors: Geoffrey Paul Smith, David Mark Dunstan Bailey, Raquel Maria Sanches-Kuiper, Harold Swerdlow, David James Earnshaw
  • Patent number: 10104798
    Abstract: The present disclosure provides security enclosures for rack mounted network devices. The security enclosures include an adjustable enclosure body, and an adjustable locking cover operatively connected to the enclosure body. The cover is movable between a closed position and an open position, and the cover has a lock assembly to lock the cover to the enclosure body when the cover is in the closed position.
    Type: Grant
    Filed: March 24, 2015
    Date of Patent: October 16, 2018
    Assignee: Hubbell Incorporated
    Inventors: Shadi Alex AbuGhazaleh, David Mark Peck, Richard James Merrell
  • Patent number: 10093136
    Abstract: An air maintenance tire assembly is provided in which an elongate groove is located within a first sidewall of a tire. The groove forms an elongate channel within the first sidewall and an elongate groove access passage extends from the elongate channel to an access opening located at an outward surface of the first sidewall. An air pumping tube inserts through the groove access passage and is positioned within the groove channel. A cover strip attaches to the first sidewall to enclose the access opening of the groove access passage. The cover strip is positioned along the first sidewall at a higher distance from the bead region of the first sidewall than the groove channel to avoid contact with a wheel rim flange when the tire is mounted to a wheel rim.
    Type: Grant
    Filed: October 30, 2015
    Date of Patent: October 9, 2018
    Assignee: The Goodyear Tire & Rubber Company
    Inventors: Thulasiram Gobinath, Patrick David Marks, Arun Kumar Byatarayanapura Gopala, Jungmee Kang, Robin Lamgaday
  • Patent number: 10081631
    Abstract: Indazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present invention concerns the use of an indazole compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, fibrotic disorders, bone or cartilage diseases, and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases and neurological conditions/disorders/diseases due to mutations or dysregulation of the Wnt pathway and/or of one or more of Wnt signaling components. Also provided are methods for treating Wnt-related disease states.
    Type: Grant
    Filed: September 27, 2017
    Date of Patent: September 25, 2018
    Assignee: Samumed, LLC
    Inventors: Sunil Kumar KC, David Mark Wallace, Jianguo Cao, Chandramouli Chiruta, John Hood
  • Publication number: 20180264217
    Abstract: A respiratory mask assembly includes a frame having a channel and a cushioning element including a clip portion adapted for interference seal and retention in the channel. The cushioning element includes an interfacing portion constructed from foam and having a wider width than the clip portion.
    Type: Application
    Filed: May 23, 2018
    Publication date: September 20, 2018
    Inventors: Lee James VELISS, Renee Frances DOHERTY, Scott Alexander HOWARD, Alicia Kristianne WELLS, Fiona Catherine CARROLL, David Mark GILLIVER, Brett Thomas LINDSAY
  • Publication number: 20180256588
    Abstract: Provided herein are compounds according to Formula I and pharmaceutically acceptable salts thereof , and compositions comprising the same, for use in various methods, including treating cancers such as colon, ovarian, pancreatic, breast, liver, prostate and hematologic cancers:
    Type: Application
    Filed: November 14, 2017
    Publication date: September 13, 2018
    Inventors: John Hood, Sunil Kumar KC, David Mark Wallace
  • Patent number: 10071086
    Abstract: Provided herein are compounds according to Formulas (I) or (II) and pharmaceutically acceptable salts thereof, and compositions comprising the same, for use in various methods, including treating cancer, abnormal cellular proliferation, angiogenesis, Alzheimer's disease, lung disease, osteoarthritis, idiopathic pulmonary fibrosis and neurological conditions/disorders/diseases.
    Type: Grant
    Filed: January 31, 2017
    Date of Patent: September 11, 2018
    Assignee: Samumed, LLC
    Inventors: John Hood, Sunil Kumar KC, David Mark Wallace
  • Publication number: 20180250269
    Abstract: Azaindazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present invention concerns the use of an azaindazole compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, fibrotic disorders, bone or cartilage diseases, and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases and neurological conditions/disorders/diseases due to mutations or dysregulation of the Wnt pathway and/or of one or more of Wnt signaling components. Also provided are methods for treating Wnt-related disease states.
    Type: Application
    Filed: November 9, 2017
    Publication date: September 6, 2018
    Inventors: Sunil Kumar KC, David Mark Wallace, Jianguo Cao, Chandramouli Chiruta, John Hood
  • Publication number: 20180251675
    Abstract: A process for producing a photochromic eyewear lens. In one embodiment at least a layer of modified photochromic poly(urea-urethane) is formed by combining photochromic material and the reaction product of a polyurethane pre-polymer and a mixture of diethyltoluene diamine and one or more polyols, plus catalyst. The mixture comprises both NH2 and OH reactive groups, with at least 0.04 equivalent weights of OH reactive species available for reaction with each 1.0 equivalent weight of excess NCO reactive species available in the pre-polymer. The lens comprising the modified photochromic poly(urea-urethane) can exhibit faster fade-back rates and better photochromic performance than lenses with non-modified poly(urea-urethane).
    Type: Application
    Filed: March 1, 2018
    Publication date: September 6, 2018
    Applicant: Younger Mfg. Co. dba Younger Optics
    Inventors: Kevin Michael Niemi, David Mark Ambler
  • Patent number: 10052331
    Abstract: Azaindazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present invention concerns the use of an azaindazole compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, fibrotic disorders, bone or cartilage diseases, and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases and neurological conditions/disorders/diseases due to mutations or dysregulation of the Wnt pathway and/or of one or more of Wnt signaling components. Also provided are methods for treating Wnt-related disease states.
    Type: Grant
    Filed: August 10, 2017
    Date of Patent: August 21, 2018
    Assignee: Samumed, LLC
    Inventors: Sunil Kumar KC, David Mark Wallace, Jianguo Cao, Chandramouli Chiruta, John Hood
  • Publication number: 20180228785
    Abstract: 4-Azaindazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present disclosure concerns the use of a 4-azaindazole compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, fibrotic disorders, bone or cartilage diseases, and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases and neurological conditions/disorders/diseases due to mutations or dysregulation of the Wnt pathway and/or of one or more of Wnt signaling components. Also provided are methods for treating Wnt-related disease states.
    Type: Application
    Filed: August 3, 2016
    Publication date: August 16, 2018
    Inventors: Sunil Kumar KC, David Mark Wallace, Jianguo Cao, Chandramouli Chiruta, John Hood
  • Patent number: PP29626
    Abstract: A new and distinct plant variety of Hesperaloe parviflora, more commonly known as Texas red yucca, with long green to purple-red tipped stems having flowers exhibiting a unique coral-orange color on the outside of the petals and yellow in the interior of the petals.
    Type: Grant
    Filed: October 31, 2016
    Date of Patent: August 28, 2018
    Assignee: Waterwise Gardening, LLC
    Inventor: David Mark Salman