Abstract: A method of preparing a whitened tobacco material is provided, including: (i) extracting a tobacco material with a first extraction solution to provide a tobacco solids material and a tobacco extract; (ii) cooking the tobacco solids material in an alkaline cooking liquid comprising sodium sulfide and having a pH of greater than 11 to form a tobacco pulp; (iii) treating the tobacco pulp with an acid to lower the pH of the tobacco pulp and provide a neutralized tobacco pulp; (iv) extracting the neutralized tobacco pulp with a second extraction solution comprising at least one chelating agent to provide an extracted tobacco pulp; and (v) bleaching the extracted tobacco pulp with a bleaching solution to provide a whitened tobacco material.

Abstract: A fuel system is provided that includes a fuel tank, a heat detector, and a control circuit. The digital heat detector is disposed in proximity to the fuel tank. The control circuit is coupled with the digital heat detector and is configured to detect that a thermal event has occurred. The fuel system is configured to implement an emergency countermeasure in response to the detection of the thermal event.

Abstract: This disclosure describes systems, methods, and computer-readable media related to retargeting online advertisement campaign recommendations for advertisements with multiple items or services. Bids may be based on a combined advertisement creative comprising two or more items or services. Dynamically selecting multiple items at bid time using a retargeting model to determine a potential revenue generation amount associated with an event may increase the probability of a conversion event based on the creative that includes the selected items. In some embodiments, a machine-learned retargeting model may be used to select multiple items to be displayed in an advertisement. The retargeting model may be applied to items that were previously viewed by the consumer and may determine a value for each of the items using factors. A bid may be calculated for each of the selected items using the values determined by the retargeting model.

Abstract: A field cover system to selectively cover, and uncover, a sports field or similar is described. The field cover system comprising a flexible resilient planar material to extend and cover the sports field, and to retract and uncover the sports field, a plurality of elongate support members, moveable to extend between a retracted position and an extended position, and one or more tensile members configured to, in use, support and/or attach to the cover and attach to the plurality of elongate support members. In the retracted position the plurality of elongate support members is located substantially below a surface level of the sports field, and in the extended position and with the tensile members attached to or supporting the cover, the elongate support members elevate the flexible resilient planar material above the sports field.

Abstract: A fuel system is provided that includes a fuel system frame and in some cases access steps. The frame can be mounted to a vehicle frame rail. Bracket assemblies can be coupled to the fuel system frame at a plurality of positions. The fuel tank can be mounted at neck portions thereof and can be supported on the frame rail between the neck portion, e.g., spaced a distance from the neck portions in a longitudinal direction of the fuel system. The access steps can be non-rectangular to provide a wide stepping portion even if the fuel system includes large tanks. The steps can be directly supported by an outside surface of the tank.

Abstract: A time-sensitive, data reduction system is described. According to an aspect of the system, a method is disclosed that comprises: receiving at least a portion of an airline-specific dataset, wherein the airline-specific dataset comprises a plurality of location records, wherein each location record comprises a point of interest (POI) and a unique rank, wherein the POI is defined by unique geographic identifier; determining a current position of the aircraft; and based on the current position and based on the unique rank of each of the plurality of location records, controlling, at a passenger display in the aircraft, a presentation of a map and a plurality of POI indicators associated with a highly-ranked subset of the plurality of location records. According to another aspect of the system, a plurality of servers are used provide relevant location-related content to an aircraft passenger.

Abstract: Methods and compositions are provided for the molecular subtyping of lung cancer samples. Specifically, a method of assessing whether a patient's adenocarcinoma lung cancer subtype is terminal respiratory unit (TRU), proximal inflammatory (PI), or proximal proliferative (PP) is provided herein. The method entails detecting the levels of the classifier biomarkers of Table 1-Table 6 or a subset thereof at the nucleic acid level, in a lung cancer sample obtained from the patient. Based in part on the levels of the classifier biomarkers, the lung cancer sample is classified as a TRU, PI, or PP sample.

Abstract: A pressure relief valve configured to vent a pressurized tank in the event of a fire is provided. The pressure relief valve includes a body, a vent passage, a plug and a latch. The vent passage is disposed through the body. The vent passage can be placed in fluid communication with an internal volume of a tank and with the atmosphere. The plug is moveably mounted in the vent passage. The latch has a blocking member disposed in contact with a control end of the plug in a first configuration and out of contact with the control end in a second configuration. The second configuration allows movement of the plug in the vent passage. One or both of a shape memory alloy wire and a trigger piston is configured to actuate the latch from the first to the second configuration. The shape memory alloy wire is configured to shorten when exposed to a temperature above a threshold temperature. The trigger piston moves, e.g.

Abstract: Methods and compositions are provided for determining a subtype of lung squamous cell carcinoma (SQ) of an individual by detecting the expression level of at least one classifier biomarker selected from a group of gene signatures for lung squamous cell carcinoma. Also provided herein are methods and compositions for determining the response of an individual with a squamous cell carcinoma subtype to a therapy such as immunotherapy.

Abstract: An interferometric optical fibre sensor comprises optical fibre defining an optical circuit configured to propagate a first optical wave via an environment in which the optical fibre can be exposed to a stimulus that modifies the first optical wave, and a second optical wave, and to combine the first optical wave and the second optical wave to create an interference signal containing information about the stimulus, wherein optical fibre propagating either or both of the first optical wave and the second optical wave comprises hollow core optical fibre configured to propagate the optical wave or waves by an antiresonant optical guidance effect.

Abstract: Disclosed embodiments include a mounting apparatus for a sliding security barrier that includes unique security features that ensure the sliding security barrier is secure and does not suffer problems that exist with conventional security doors and windows. The sliding security barrier is configured to be implemented using tracks that are common to conventional sliding patio screen door or windows. Additional security features include a unique striker plate, a lift protector at a corner, adjustable top and/or bottom channel caps, an interlock, and a uniquely shaped lock. These features provide greater security at a lower cost because they use an existing sliding door or window sash and channels but provide a secure attachment that inhibits tampering and removal of the sliding screen barrier.

Abstract: The present disclosure relates to a light source system suitable for use in a time of flight camera. The light source system includes a light source, such as a laser, and a driver arranged to supply a drive current to the light source to turn the light source on to emit light. The driver includes or is coupled to a capacitor to store energy and then discharge to generate the drive current. The driver can be integrated into a semiconductor die on which the light source is mounted. Thus, the driver can include within it the source of energy for the drive current and the light source and driver can be very close together, Therefore, the light source may be turned on and off very quickly, such as with a relatively large drive current, such as to output a high optical power, short duration light pulse.

Abstract: The present disclosure relates to devices, methods, and computer-readable medium for saving and restoring physical hardware states and virtual machine (VM) states for an application actively being executed on a virtual machine by a user on a computer device. The devices, methods, and computer-readable medium may allow a user to suspend a current state of an application session and save the VM and memory state to persistent storage, and later resume the execution of the saved application session by reading the state back into memory and restoring the VM state.

Abstract: The disclosure provides a product including a plurality of beads configured for oral use, the plurality of beads containing bleached plant material, a filler, a binder, water, and at least one flavoring agent, active ingredient, or a combination thereof. Further provided are pouched products including the plurality of beads, and a process for preparing the beads.

Abstract: A discovery protocol for use in a mobile telecommunications network where the protocol is used to discover a target core network component of the network. The network comprises base station core network components having at least one Mobile Management Entity (MME), a Serving Gateway (SGW) a Packet Gateway (PGW), an HSS; and a discovery request distributor connected to all other network components. The protocol utilizes the steps of: sending a discovery request from a first core network component to a discovery request distributor, where the discovery request includes a target identifier of a target core network component to be discovered; forwarding the discovery request to all other core network components within the network; receiving a discovery response at the first network component, from an identified target core network component with the defined target identifier and no responses from the other target core network components.

Abstract: The disclosure provides oral pouched products in the form of a porous pouch defining a cavity containing a composition adapted for oral use, wherein the porous pouch is formed from a fleece material comprising two or more layers, wherein the two or more layers are in direct contact with one another. The disclosure also provides pouched products that include at least one layer of fleece material and at least one layer of a gel that is in direct contact with the fleece material. The disclosure also provides methods of forming such pouched products and for controlling/tailoring certain properties of pouched products using such multi-layered and/or gel-based approaches.

Abstract: The present disclosure relates to a light source system suitable for use in a time of flight camera. The light source system includes a light source, such as a laser, and a driver arranged to supply a drive current to the light source to turn the light source on to emit light. The driver includes a capacitor to store energy and then discharge to generate the drive current, and the driver is integrated into a semiconductor die on which the light source is mounted. Consequently, the driver includes within it the source of energy for the drive current and the light source and driver are very close together, meaning that the light source may be turned on and off very quickly with a relatively large drive current, in order to output a high optical power, short duration light pulse.

Abstract: The present disclosure relates to a light source system suitable for use in a time of flight camera. The light source system includes a light source, such as a laser, and a driver arranged to supply a drive current to the light source to turn the light source on to emit light. The driver includes two transistors coupled to the light source in series, such that when both transistors are turned on, a drive circuit is completed, current flows and the light source turns on. A very short pulse of light emission may be achieved efficiently by switching one of the transistors to the on-state to complete the drive circuit and a short time later turning off the other transistor in order to break the drive circuit. In this way, a pulse of light in the order of less than 1 nanosecond or less than 500 picoseconds may be achieved.

Abstract: A pressure vessel has an interior chamber and includes an outer shell, a boss, and an internal liner disposed within the outer shell. The boss includes a port extending between the interior chamber and an exterior of the pressure vessel; and an annular flange extending radially from the port and having an exterior surface and an interior surface. The liner includes an exterior portion adjacent the exterior surface of the flange; an interior portion adjacent the interior surface of the flange; and a vent in the interior portion. A method for forming a pressure vessel includes mounting a boss on a mandrel, flowing a non-metallic polymer around a flange of the boss to form an internal liner of the pressure vessel, forming a vent in an interior portion of the liner; and forming an outer shell surrounding the liner and at least a portion of the flange of the boss.

Abstract: Methods and compositions are provided for determining a subtype of lung adenocarcinoma (AD) of an individual by detecting the expression level of at least one classifier biomarker selected from a group of gene signatures for lung adenocarcinoma. Also provided herein are methods and compositions for determining the response of an individual with an adenocarcinoma subtype to a therapy such as immunotherapy.