Patents by Inventor David Osborne

David Osborne has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20070258919
    Abstract: Increased compliance in the use of topical sunscreens is obtained by combining a topical sunscreen agent in a formulation containing an antibacterial medication such as azelaic acid or an antibiotic.
    Type: Application
    Filed: June 27, 2007
    Publication date: November 8, 2007
    Inventors: Arturo Angel, David Osborne, Gordon Dow
  • Publication number: 20070207192
    Abstract: The present invention is directed to a mucoadhesive delivery system for the local or systemic administration of a pharmaceutical agent. The delivery system of the invention effectively and facilely enables transport of the pharmaceutical agent through mucosal membranes and into the vasculattire of the mucosa. The delivery system includes an at least partially water soluble bioadhesive layer and an at least partially water soluble backing layer. Incorporated within either or both of these layers are the pharmaceutical agent and a mucosal penetration enhancing agent. The mucosal penetration enhancing agent displays localized tissue irritation properties. The mucoadhesive delivery system may be in the form of a gel, film, disc or patch. It may be applied to any mucosal membrane of a patient including but not limited to those of the buccal and nasal cavities, throat, eye, vagina, alimentary tract and peritoneum.
    Type: Application
    Filed: December 22, 2006
    Publication date: September 6, 2007
    Applicant: QLT USA, Inc.
    Inventors: Richard Holl, David Osborne
  • Patent number: 7254747
    Abstract: A technique is provided for selecting among a plurality of service models for addressing serviceable events and faults in a complex machine system. Indicators established for each of the models serve as the basis for comparison to input data acquired from the complex system or from manual or semi-automated data acquisition methods. Based upon the comparisons, and upon flexible selection criteria, one or more of the service models is selected to most efficiently address the most likely root cause of the serviceable event or fault.
    Type: Grant
    Filed: March 28, 2003
    Date of Patent: August 7, 2007
    Assignee: General Electric Company
    Inventors: Mark David Osborn, Rasiklal Punjalal Shah, Jieqian Cathy Chen
  • Patent number: 7249284
    Abstract: A technique is provided for designing and evaluating service models for components, functions, subsystems and field replaceable units in a complex machine system. At a component or item level, each model identifies various items, failure modes, and so forth which may be the root cause of anticipated serviceable events or faults. The design tools permit numerous interfaces to be used in the design of service models, and in the evaluation of the degree to which the models address detectability and isolation capabilities for the root causes of serviceable events and faults.
    Type: Grant
    Filed: March 28, 2003
    Date of Patent: July 24, 2007
    Assignee: GE Medical Systems, Inc.
    Inventors: Rasiklal Punjalal Shah, Vrinda Rajiv, Mark David Osborn, Catherine Mary Graichen, Amey Sudhakar Joshi, Sreevidya Sambasivan, Jieqian Cathy Chen, Ernest Joseph Waldron
  • Publication number: 20070122435
    Abstract: The present invention relates to a method of treating acne by topically applying a dermatological composition comprising dapsone. In addition to inflammatory lesions, the composition also treats non-inflammatory acne. The composition is formulated to include dapsone in a both a dissolved and microparticulate state.
    Type: Application
    Filed: December 12, 2006
    Publication date: May 31, 2007
    Inventor: David Osborne
  • Publication number: 20060204526
    Abstract: The present invention relates to a topical, emulsive composition containing Dapsone or its derivative. The inventive composition incorporates emollients and Dapsone or its derivative in a stable emulsion. The stability is achieved through the use of a combination of certain surfactant mixtures and an enhancer providing solubility of the Dapsone.
    Type: Application
    Filed: February 13, 2006
    Publication date: September 14, 2006
    Inventors: Robert Lathrop, David Osborne
  • Patent number: 7103509
    Abstract: A method for predicting a time to failure of a component in a system is presented. The method comprises obtaining a set of data measurements related to the component. The set of data measurements are representative of a plurality of parameters including a plurality of leading parameters. The method comprises generating a prediction model based upon the leading parameters considered in combination. The prediction model is then used to predict the time to failure of the component based on a set of real-time measurements, wherein the plurality of parameters are processed to predict the time to failure for the component. Finally, a confidence level for the predicted time to failure is determined based upon the plurality of parameters.
    Type: Grant
    Filed: November 23, 2004
    Date of Patent: September 5, 2006
    Assignee: General Electric Company
    Inventors: Rasiklal Punjalal Shah, Vrinda Rajiv, Mark David Osborn, Mahesh Kumar Asati, Piero Patrone Bonissone
  • Patent number: 6964040
    Abstract: Optimizing storage and retrieval of monitoring data. In one aspect of this disclosure, there is a system, method and computer readable medium that stores instructions for instructing a computer system, to optimize storage and retrieval of data. In this embodiment, a transfer manager component acquires the data from an archive and assigns predetermined storage values to specified parameters that form the data structure of the acquired data. A database stores the data acquired by the transfer manager component in accordance with the predetermined storage values. A middle tier component extracts the data in the database and interpolates the data in accordance with the predetermined storage values.
    Type: Grant
    Filed: May 23, 2001
    Date of Patent: November 8, 2005
    Assignee: General Electric Company
    Inventor: Mark David Osborn
  • Publication number: 20050186156
    Abstract: The present invention provides a method for protecting against UV radiation-induced skin damage. Specifically, compositions including dapsone are administered to provide UV protection. The dapsone compositions may be administered orally, or by other parenteral routes, such as topically, transdermally, by inhalation, and the like.
    Type: Application
    Filed: December 14, 2004
    Publication date: August 25, 2005
    Inventor: David Osborne
  • Publication number: 20050147658
    Abstract: The present invention relates to a pharmaceutical delivery device for application of a pharmaceutical to mucosal surfaces. The device comprises an adhesive layer and a non-adhesive backing layer, and the pharmaceutical may be provided in either or both layers. Upon application, the device adheres to the mucosal surface, providing localized drug delivery and protection to the treatment site. The kinetics of erodability are easily adjusted by varying the number of layers and/or the components.
    Type: Application
    Filed: March 1, 2005
    Publication date: July 7, 2005
    Inventors: Gilles Tapolsky, David Osborne
  • Publication number: 20050048102
    Abstract: The present invention relates to a pharmaceutical delivery device for application of a pharmaceutical to mucosal surfaces. The device comprises an adhesive layer and a non-adhesive backing layer, and the pharmaceutical may be provided in either or both layers. Upon application, the device adheres to the mucosal surface, providing localized drug delivery and protection to the treatment site. The kinetics of erodability are easily adjusted by varying the number of layers and/or the components.
    Type: Application
    Filed: October 12, 2004
    Publication date: March 3, 2005
    Inventors: Gilles Tapolsky, David Osborne
  • Publication number: 20050013845
    Abstract: The present invention provides bioerodible, water-soluble pharmaceutical carriers for ocular (e.g., transconjunctival or transcorneal) delivery of pharmaceuticals for either systemic or local therapy.
    Type: Application
    Filed: November 12, 2003
    Publication date: January 20, 2005
    Inventors: Stephen Warren, David Osborne, Richard Holl
  • Publication number: 20040205398
    Abstract: A technique is provided for selecting among a plurality of service models for addressing serviceable events and faults in a complex machine system. Indicators established for each of the models serve as the basis for comparison to input data acquired from the complex system or from manual or semi-automated data acquisition methods. Based upon the comparisons, and upon flexible selection criteria, one or more of the service models is selected to most efficiently address the most likely root cause of the serviceable event or fault.
    Type: Application
    Filed: March 28, 2003
    Publication date: October 14, 2004
    Inventors: Mark David Osborn, Rasiklal Punjalal Shah, Jieqian Cathy Chen
  • Publication number: 20040193958
    Abstract: A technique is provided for designing and evaluating service models for components, functions, subsystems and field replaceable units in a complex machine system. At a component or item level, each model identifies various items, failure modes, and so forth which may be the root cause of anticipated serviceable events or faults. The design tools permit numerous interfaces to be used in the design of service models, and in the evaluation of the degree to which the models address detectability and isolation capabilities for the root causes of serviceable events and faults.
    Type: Application
    Filed: March 28, 2003
    Publication date: September 30, 2004
    Inventors: Rasiklal Punjalal Shah, Vrinda Rajiv, Mark David Osborn, Catherine Mary Graichen, Amey Sudhakar Joshi, Sreevidya Sambasivan, Jieqian Cathy Chen, Ernest Joseph Waldron
  • Patent number: 6792766
    Abstract: A thermal zone demand controlled air conditioning fan coil unit using dual cascade arranged heat pumps, chilled water, or a combination of chilled water and hot water, with or without back up electric resistance heat strips, and having an air circulation system for circulating air to and from a plurality of thermal zones and including a conditioned air chamber having first and second heat exchange refrigerant coils or direct or reversed cycle water coils being connected in refrigerant circulating relation respectively with the heat pumps, chilled water coil. A plurality of thermal zone blowers conduct conditioned air from the conditioned air chamber to respective thermal zones of a building space. Electronic controller circuitry of the system is coupled for thermal demand control of the heat pumps and the thermal zone blowers for operation of the first heat pump during average thermal load and for operation of both heat pumps during greater thermal load.
    Type: Grant
    Filed: October 4, 2002
    Date of Patent: September 21, 2004
    Assignee: Cascade Manufacturing, L.P.
    Inventors: David Osborne, Brian Chester, Gary R. Scoggins
  • Publication number: 20040065095
    Abstract: A thermal zone demand controlled air conditioning fan coil unit using dual cascade arranged heat pumps, chilled water, or a combination of chilled water and hot water, with or without back up electric resistance heat strips, and having an air circulation system for circulating air to and from a plurality of thermal zones and including a conditioned air chamber having first and second heat exchange refrigerant coils or direct or reversed cycle water coils being connected in refrigerant circulating relation respectively with the heat pumps, chilled water coil A plurality of thermal zone blowers conduct conditioned air from the conditioned air chamber to respective thermal zones of a building space. Electronic controller circuitry of the system is coupled for thermal demand control of the heat pumps and the thermal zone blowers for operation of the first heat pump during average thermal load and for operation of both heat pumps during greater thermal load.
    Type: Application
    Filed: October 4, 2002
    Publication date: April 8, 2004
    Applicant: CASCADE MANUFACTURING, L.P.
    Inventors: David Osborne, Brian Chester, Gary R. Scoggins
  • Patent number: 6716546
    Abstract: A system 10 is provided for supplying air to a fuel cell 12 for use within a vehicle 14. The system 10 includes a conventional storage tank 16 which receives and stores hydrogen gas at a relatively high pressure, an expander unit 18, a compressor unit 20, pressure regulators 22, 24, a valve 26, a controller 30, and vehicle sensors 32, and a secondary compressor 34. The system 10 selectively channels pressurized hydrogen gas through expander unit 18 which lowers the pressure of the hydrogen gas and rotatably drives compressor 20. By utilizing the potential energy within the hydrogen gas to drive compressor 20, system 10 conserves energy and improves the overall fuel economy of the vehicle 14.
    Type: Grant
    Filed: May 4, 2001
    Date of Patent: April 6, 2004
    Assignee: Ford Motor Company
    Inventors: Keith Andrew Oglesby, Kurt David Osborne, Woong-chul Yang
  • Publication number: 20040024667
    Abstract: An apparatus for deciding credit, the apparatus comprising: a customer identification module adapted for generating customer identification data from salesperson input data; a customer financial data acquisition module adapted for transmitting the customer identification data to a financial data provider and receiving customer financial data from the financial data provider using a communications network; and a credit limit calculator adapted for calculating a credit limit from the customer financial data and from a reasoning model structure using Example Based Evidential Reasoning and for transmitting the credit limit to a credit provider using the communications network.
    Type: Application
    Filed: July 31, 2002
    Publication date: February 5, 2004
    Inventors: James Patrick Quaile, Srinivas Bollapragada, Prasanthi Venkata Surya Phani Ganti, Kannan Ramanathan, Mark David Osborn
  • Patent number: 6628006
    Abstract: A system 10 is provided for recovering the potential energy of a hydrogen gas fuel supply within a fuel cell powered vehicle 14. The system 10 includes a conventional storage tank 16 which receives and stores hydrogen gas at a relatively high pressure, an expander 18, a compressor 20, a motor/generator 76 which selectively generates electrical power and torque, pressure regulators 22, 24, a valve 26, an electrical charge storage device or battery 28, a controller 30, vehicle sensors 32 and electrical switches or switching module 34. The system 10 selectively channels pressurized hydrogen gas through expander 18 which lowers the pressure of the hydrogen gas, rotatably drives compressor 20 and generates electricity. Controller 30 causes the generated electricity to be selectively communicated to electrical accessories 72, and/or to battery 28 by use of switching module 34, based upon vehicle attribute data received from sensors 32.
    Type: Grant
    Filed: May 3, 2001
    Date of Patent: September 30, 2003
    Assignee: Ford Motor Company
    Inventors: Keith Andrew Oglesby, Kurt David Osborne, Woong-chul Yang
  • Patent number: D488448
    Type: Grant
    Filed: July 11, 2002
    Date of Patent: April 13, 2004
    Inventor: Jeremy David Osborn Ranger