Patents by Inventor David P. Stumbo

David P. Stumbo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11878302
    Abstract: System, including methods and apparatus, for spacing droplets from each other and for detection of spaced droplets.
    Type: Grant
    Filed: September 2, 2021
    Date of Patent: January 23, 2024
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: George Carman, Thomas H. Cauley, III, David P. Stumbo
  • Publication number: 20230070234
    Abstract: Systems and methods for detection of a signal from droplets of an emulsion. An exemplary system may comprise a fluid transporter having a tube with an open end for aspirating droplets, a singulator to arrange the droplets in single file and to space the single-file droplets from one another, and a detection channel in optical communication with a detector configured to detect a signal from droplets. In some embodiments, the singulator may have a channel junction at which a stream of droplets in single file is combined with a stream of spacing fluid, and a tapered spacing channel extending downstream from the channel junction toward the detection channel. In some embodiments, the fluid transporter may suck droplet-containing fluid and spacing fluid through the detection channel from respective sources. In some embodiments, droplets may be subjected to a disaggregation routine before they are passed through the detection channel.
    Type: Application
    Filed: November 14, 2022
    Publication date: March 9, 2023
    Applicant: Bio-Rad Laboratories, Inc.
    Inventors: David P. STUMBO, George CARMAN, Steve HOBBS, Anthony J. MAKAREWICZ, JR., Dmitri SIMONIAN, David GLADE, Joshua OEN, Denis PRISTINSKI, John DZENITIS
  • Patent number: 11499183
    Abstract: Systems and methods for detection of a signal from droplets of an emulsion. An exemplary system may comprise a fluid transporter having a tube with an open end for aspirating droplets, a singulator to arrange the droplets in single file and to space the single-file droplets from one another, and a detection channel in optical communication with a detector configured to detect a signal from droplets. In some embodiments, the singulator may have a channel junction at which a stream of droplets in single file is combined with a stream of spacing fluid, and a tapered spacing channel extending downstream from the channel junction toward the detection channel. In some embodiments, the fluid transporter may suck droplet-containing fluid and spacing fluid through the detection channel from respective sources. In some embodiments, droplets may be subjected to a disaggregation routine before they are passed through the detection channel.
    Type: Grant
    Filed: June 28, 2018
    Date of Patent: November 15, 2022
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: David P. Stumbo, George Carman, Steve Hobbs, Anthony J. Makarewicz, Jr., Dmitri Simonian, David Glade, Joshua Oen, Denis Pristinski, John Dzenitis
  • Publication number: 20210394189
    Abstract: System, including methods and apparatus, for spacing droplets from each other and for detection of spaced droplets.
    Type: Application
    Filed: September 2, 2021
    Publication date: December 23, 2021
    Inventors: George Carman, Thomas H. Cauley, III, David P. Stumbo
  • Patent number: 11110458
    Abstract: System, including methods and apparatus, for spacing droplets from each other and for detection of spaced droplets.
    Type: Grant
    Filed: February 3, 2014
    Date of Patent: September 7, 2021
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: George Carman, Thomas H. Cauley, III, David P. Stumbo
  • Patent number: 11022785
    Abstract: Detection system comprising an examination region, a one-piece optical element including a focusing portion to concentrate light received from the examination region and a guiding portion to homogenize light received from the focusing portion, and a detector configured to detect homogenized light received from the guiding portion.
    Type: Grant
    Filed: January 16, 2020
    Date of Patent: June 1, 2021
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Denis Pristinski, David P. Stumbo
  • Publication number: 20200150410
    Abstract: Detection system comprising an examination region, a one-piece optical element including a focusing portion to concentrate light received from the examination region and a guiding portion to homogenize light received from the focusing portion, and a detector configured to detect homogenized light received from the guiding portion.
    Type: Application
    Filed: January 16, 2020
    Publication date: May 14, 2020
    Applicant: Bio-Rad Laboratories, Inc.
    Inventors: Denis PRISTINSKI, David P. STUMBO
  • Patent number: 10551603
    Abstract: Detection system comprising an examination region, a one-piece optical element including a focusing portion to concentrate light received from the examination region and a guiding portion to homogenize light received from the focusing portion, and a detector configured to detect homogenized light received from the guiding portion.
    Type: Grant
    Filed: July 21, 2017
    Date of Patent: February 4, 2020
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Denis Pristinski, David P. Stumbo
  • Patent number: 10490817
    Abstract: The present invention relates to nanostructured materials (including nanowires) for use in batteries. Exemplary materials include carbon-comprising, Si-based nanostructures, nanostructured materials disposed on carbon-based substrates, and nanostructures comprising nanoscale scaffolds. The present invention also provides methods of preparing battery electrodes, and batteries, using the nanostructured materials.
    Type: Grant
    Filed: May 19, 2010
    Date of Patent: November 26, 2019
    Assignee: OneD Material LLC
    Inventors: Yimin Zhu, Jay L. Goldman, Jason Hartlove, Hans Jurgen Hofler, Baixin Qian, Vijendra Sahi, Ionel C. Stefan, David P. Stumbo
  • Publication number: 20190002956
    Abstract: Systems and methods for detection of a signal from droplets of an emulsion. An exemplary system may comprise a fluid transporter having a tube with an open end for aspirating droplets, a singulator to arrange the droplets in single file and to space the single-file droplets from one another, and a detection channel in optical communication with a detector configured to detect a signal from droplets. In some embodiments, the singulator may have a channel junction at which a stream of droplets in single file is combined with a stream of spacing fluid, and a tapered spacing channel extending downstream from the channel junction toward the detection channel. In some embodiments, the fluid transporter may suck droplet-containing fluid and spacing fluid through the detection channel from respective sources. In some embodiments, droplets may be subjected to a disaggregation routine before they are passed through the detection channel.
    Type: Application
    Filed: June 28, 2018
    Publication date: January 3, 2019
    Inventors: David P. STUMBO, George CARMAN, Steve HOBBS, Anthony J. MAKAREWICZ, JR., Dmitri SIMONIAN, David GLADE, Joshua OEN, Denis PRISTINSKI, John DZENITIS
  • Patent number: 10060847
    Abstract: Systems and methods for detecting and processing signals from particles. In an exemplary method, particles may be passed through a zone of a channel, while the zone is irradiated with light. Interaction of the light with the particles may deflect light and induce photoluminescence. A deflection signal and a photoluminescence signal may be detected from the zone. Particle waveforms may be identified in the deflection signal. At least a subset of the particle waveforms may be double-peak waveforms including a pair of peaks corresponding to a particle entering and exiting the zone. Amplitudes may be obtained from the photoluminescence signal. The amplitudes may correspond to respective particles and their particle waveforms, and at least a subset of the amplitudes may correspond to the double-peak waveforms. Individual particles may be assigned as positive or as negative for an analyte based on the corresponding amplitudes.
    Type: Grant
    Filed: December 29, 2016
    Date of Patent: August 28, 2018
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Yunfeng Ling, David P. Stumbo, George Carman, Denis Pristinski
  • Publication number: 20170322401
    Abstract: Detection system comprising an examination region, a one-piece optical element including a focusing portion to concentrate light received from the examination region and a guiding portion to homogenize light received from the focusing portion, and a detector configured to detect homogenized light received from the guiding portion.
    Type: Application
    Filed: July 21, 2017
    Publication date: November 9, 2017
    Inventors: Denis Pristinski, David P. Stumbo
  • Patent number: 9726871
    Abstract: Detection system comprising an examination region, a one-piece optical element including a focusing portion to concentrate light received from the examination region and a guiding portion to homogenize light received from the focusing portion, and a detector configured to detect homogenized light received from the guiding portion.
    Type: Grant
    Filed: January 31, 2014
    Date of Patent: August 8, 2017
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Denis Pristinski, David P. Stumbo
  • Publication number: 20170191923
    Abstract: Systems and methods for detecting and processing signals from particles. In an exemplary method, particles may be passed through a zone of a channel, while the zone is irradiated with light. Interaction of the light with the particles may deflect light and induce photoluminescence. A deflection signal and a photoluminescence signal may be detected from the zone. Particle waveforms may be identified in the deflection signal. At least a subset of the particle waveforms may be double-peak waveforms including a pair of peaks corresponding to a particle entering and exiting the zone. Amplitudes may be obtained from the photoluminescence signal. The amplitudes may correspond to respective particles and their particle waveforms, and at least a subset of the amplitudes may correspond to the double-peak waveforms. Individual particles may be assigned as positive or as negative for an analyte based on the corresponding amplitudes.
    Type: Application
    Filed: December 29, 2016
    Publication date: July 6, 2017
    Inventors: Yunfeng Ling, David P. Stumbo, George Carman, Denis Pristinski
  • Publication number: 20160281256
    Abstract: Methods, systems, and apparatuses for nanowire deposition are provided. A deposition system includes an enclosed flow channel, an inlet port, and an electrical signal source. The inlet port provides a suspension that includes nanowires into the channel. The electrical signal source is coupled to an electrode pair in the channel to generate an electric field to associate at least one nanowire from the suspension with the electrode pair. The deposition system may include various further features, including being configured to receive multiple solution types, having various electrode geometries, having a rotatable flow channel, having additional electrical conductors, and further aspects.
    Type: Application
    Filed: June 8, 2016
    Publication date: September 29, 2016
    Inventors: Erik FREER, James M. HAMILTON, David P. STUMBO, Kenji KOMIYA, Akihide SHIBATA
  • Patent number: 9390951
    Abstract: Methods, systems, and apparatuses for nanowire deposition are provided. A deposition system includes an enclosed flow channel, an inlet port, and an electrical signal source. The inlet port provides a suspension that includes nanowires into the channel. The electrical signal source is coupled to an electrode pair in the channel to generate an electric field to associate at least one nanowire from the suspension with the electrode pair. The deposition system may include various further features, including being configured to receive multiple solution types, having various electrode geometries, having a rotatable flow channel, having additional electrical conductors, and further aspects.
    Type: Grant
    Filed: July 24, 2014
    Date of Patent: July 12, 2016
    Assignee: SHARP KABUSHIKI KAISHA
    Inventors: Erik Freer, James M. Hamilton, David P. Stumbo, Kenji Komiya, Akihide Shibata
  • Patent number: 8999851
    Abstract: The present invention relates to methods of forming substrate elements, including semiconductor elements such as nanowires, transistors and other structures, as well as the elements formed by such methods.
    Type: Grant
    Filed: December 9, 2008
    Date of Patent: April 7, 2015
    Assignee: OneD Material LLC
    Inventors: Francisco Leon, Francesco Lemmi, Jeffrey Miller, David Dutton, David P. Stumbo
  • Publication number: 20140331930
    Abstract: Methods, systems, and apparatuses for nanowire deposition are provided. A deposition system includes an enclosed flow channel, an inlet port, and an electrical signal source. The inlet port provides a suspension that includes nanowires into the channel. The electrical signal source is coupled to an electrode pair in the channel to generate an electric field to associate at least one nanowire from the suspension with the electrode pair. The deposition system may include various further features, including being configured to receive multiple solution types, having various electrode geometries, having a rotatable flow channel, having additional electrical conductors, and further aspects.
    Type: Application
    Filed: July 24, 2014
    Publication date: November 13, 2014
    Applicants: SHARP KABUSHIKI KAISHA, OneD Material LLC
    Inventors: Erik Freer, James M. Hamilton, David P. Stumbo, Kenji Komiya, Akihide Shibata
  • Publication number: 20140218719
    Abstract: Detection system comprising an examination region, a one-piece optical element including a focusing portion to concentrate light received from the examination region and a guiding portion to homogenize light received from the focusing portion, and a detector configured to detect homogenized light received from the guiding portion.
    Type: Application
    Filed: January 31, 2014
    Publication date: August 7, 2014
    Applicant: Bio-Rad Laboratories, Inc.
    Inventors: Denis Pristinski, David P. Stumbo
  • Publication number: 20140221239
    Abstract: System, including methods and apparatus, for spacing droplets from each other and for detection of spaced droplets.
    Type: Application
    Filed: February 3, 2014
    Publication date: August 7, 2014
    Applicant: Bio-Rad Laboratories, Inc.
    Inventors: George Carman, Thomas H. Cauley, III, David P. Stumbo