Abstract: A system and method for optimizing advertisements for display to users comprising receiving a request for an advertisement wherein the request comprises information about a user to whom the advertisement is to be displayed; determining at least one community of which the user is a member; determining a conditional probability that the user will interact with the advertisement; responsive to the conditional probability exceeding a threshold, determining community data to present with the advertisement and providing for display to the user the advertisement and the community data; responsive to the providing of the advertisement, receiving an indication of activity at a client system related to the advertisement or community data; and storing the indication in a storage medium.

Abstract: A self-powered in-core detector arrangement for measuring flux in a nuclear reactor core includes a first in-core detector and a second in-core detector. The first in-core detector includes a first flux detecting material, a first lead wire extending longitudinally from a first axial end of the first flux detecting material, a first insulating material surrounding outer diameters of the first flux detecting material and the first lead wire and a first sheath surrounding the first insulating material. The first sheath includes a first section surrounding the first flux detecting material and a second section surrounding the first lead wire. The first section of the first sheath has a greater outer diameter than the second section of the first sheath.

Abstract: A powder bed fusion apparatus for building an object in a layer-by-layer manner includes a build platform movable within a build sleeve to define a build volume, a layer formation device for forming layers of powder across the build volume in a working plane and an irradiation device for irradiating powder in the working plane to selectively fuse the powder. The powder bed fusion apparatus further includes a mechanical manipulator arranged to engage with the object and/or a build substrate, to which the object is attached, to tilt the object in a raised position above the working plane such that powder is freed from the object and deposited at a location above the working plane and/or into the build volume.

Abstract: Disclosed herein is an apparatus (10) for remediation of a site contaminated by an oil spill. The apparatus (10) comprises a porous capsule (12) encapsulating material (14) for sorbing oil. The material (14) comprises granules of an at least semi-open cell polymeric foam, the granules being less than 10cm3 in size. Ingredients from which the polymeric foam is formed comprise acrylonitrile butadiene rubber as a major constituent thereof by weight.

Abstract: A method of configuring a medical device for a patient comprising: receiving information relating to a patient, the patient requiring a medical device, determining and/or receiving a medical device configuration for the medical device, the medical device configuration being suitable for the patient, uploading the medical device configuration to a server, wherein, the medical device configuration on the server is for later download by the device when the patient has received their medical device and activated the medical device.

Abstract: Apparatuses, systems, and methods for prosthetic valves. Embodiments of prosthetic valves may include sealing bodies configured for an anchor to at least partially pass through. The pass through may allow for the sealing body to seal to a portion of a patient's heart in the event of a miscapture of a leaflet by the anchor. Embodiments may include modular valve systems and prosthetic valves including anchors for coupling to chordae, trabeculae, or papillary structures of a patient's heart. Embodiments may include prosthetic valves including anchors for engaging calcification of a patient's native valve.

Abstract: Disclosed herein are embodiments of a delivery system which can be used to recapture and/or reposition a replacement valve, such as a replacement mitral valve, after initial deployment of the valve. Embodiments of the disclosure can use the crimping/tensioning of sutures in order to re-crimp the replacement valve after release, though longitudinal or rotational forces.

Abstract: Features are disclosed for performing functions in response to user requests. Natural Language Understanding (“NLU”) processing may be performed to generate command data that represents a subject of an utterance. The command data may be sent to an application that causes presentation of first output content in a first modality at a first time in response to receiving the command data, and generates second output content in a second modality different from the first modality, wherein the second output content is associated with the first output content. The second output content may be presented in the second modality at a second time subsequent to the first time.

Abstract: Systems and methods for energy storage system are provided. The system includes a particle regeneration subsystem for applying electrical energy to regenerate metallic particulate fuel; a fuel storage subsystem for storing metallic particulate fuel, the fuel storage subsystem in fluid communication with the particle regeneration subsystem; and a power generation subsystem for producing electrical energy from the metallic particulate fuel, the power generation subsystem in fluid communication with the fuel storage subsystem; a bearer electrolyte for transporting the metallic particulate fuel through the particle regeneration subsystem, the fuel storage subsystem and the power generation subsystem; and a control unit configured to independently control flow of the bearer electrolyte between the particle regeneration subsystem and the fuel storage subsystem, and the fuel storage subsystem and the power generation subsystem.

Abstract: A humidification system can include a heater base, a chamber, and a breathing circuit. The heater base includes a heater plate positioned in a recessed region, and a heat conductive portion of the chamber is configured to contact the heater plate. The heater base includes a guard configured to control movement of the chamber into and out of the recessed region. The guard includes an anti-racking mechanism. The chamber includes an inlet port, an outlet port. A downward extension extends into the chamber from the inlet port, and a baffle is disposed at a lower end of the downward extension. A component of the breathing circuit can include a conduit hanging end cap for shipping and storage. The end cap can include a hanging component to allow the breathing circuit component to be hung from a medical stand. The system can detect when breathing circuits are connected in reverse.

Abstract: Disclosed herein include systems, devices, computer readable media, and methods for subsampling flow cytometric event data. First and second flow cytometric event data can be transformed into a lower-dimensional space, associated with a plurality of bins, and assigned to a first bin and a second bin. Subsampled flow cytometric event data comprising the first flow cytometric event data can be generated. The subsampled flow cytometric event data can comprise the second flow cytometric event data if the first bin and the second bin are different. The subsampled flow cytometric event data may not comprise the second flow cytometric event data if the first bin and the second bin are identical.

Abstract: Systems and methods for remotely monitoring liquids that are stored in containers in a storage facility are provided. A radiating cable that is in communication with a receiver is routed through the storage facility. Liquid monitoring systems are associated with each container and broadcast signals that are received by the radiating cables. Various aspects of the liquid can be monitored, such as volume level, atmospheric pressure, humidity, and temperature via sensors of the liquid monitoring system.

Abstract: Systems and methods are disclosed for detecting Cherenkov radiation produced during radiotherapy. A radiotherapy system comprises a patient receiving space for receiving a patient, a therapeutic radiation source, and a light detector configured to detect Cherenkov radiation subsequent to the emission of therapeutic radiation. Optionally, the system may make use of a optically transmissive dielectric to produce Cherenkov radiation.

Abstract: A quick-release rifle mounting system, comprising: (a) a mounting panel having a back side for securely engaging to an interior surface of a bag, and a front side having at least two panel loops extending therefrom, whereby each panel loop forms an open channel between the panel loop and the front side of the mounting panel; and (b) a quick-release strap has a grip portion and two strap portions, each strap portion having an end attached to the grip portion, and a free end sized to be threaded through the channels on the front side of the mounting panel. The strap portions are releasably attached at their ends to form strap loops.

Abstract: An air cleaner assembly having a lighting arrangement which emits ultraviolet (UV) light for the purpose of disinfecting air which is circulated through the air cleaner assembly, and which disinfected air is then discharged from the assembly. The air cleaning assembly may be utilized in conjunction with an upright space-dividing wall panel system, such as those used in office or work areas.

Abstract: The present invention relates to IL-8 inhibitor compounds, preferably dual CXCR1/CXCR2 receptor inhibitors, useful in the treatment and/or prevention of some sarcomas, preferably in the treatment and/or prevention of osteosarcoma, Ewing sarcoma, rhabdomyosarcoma or lung metastasis associated thereof.

Abstract: A replacement mitral valve prosthesis includes a support structure and a valve body having three flexible leaflets. The support structure preferably includes an internal valve frame and an external sealing frame. The valve frame supports the flexible leaflets. The sealing frame is adapted to conform to the shape of the native mitral valve annulus. The sealing frame may be coupled to an inlet end of the valve frame, an outlet end of the valve frame, or both. A plurality of anchors is coupled to the outlet end of the valve frame. The anchors extend radially outwardly for placement behind native leaflets. The prosthesis preferably includes a skirt disposed along an exterior of the external sealing frame. The prosthesis is collapsible for delivery into the heart via a delivery catheter. The prosthesis is configured to self-expand for deployment in the heart when released from the delivery catheter.

Abstract: A biomarker detection apparatus in which a CMOS-based chip is used to generate independent detection signals from a reaction zone that receives a biological sample, where the biological sample is provided to both a test region and positive and negative control regions within the reaction zone. The independent detection signals can be processed together (i.e. as a group of input parameters for an algorithm) to identify the presence of a biomarker (or a plurality of biomarkers) in a biological sample. The use of sample-specific, independently detectable positive and negative controls facilitates improved detection accuracy.

Abstract: This invention relates to a breath indicator that is receivable by a part of a breathing assistance apparatus that supplies gas to a patient. The indicator comprises an elongate body having a gas sampling end and an attachment end. The attachment end is adapted to attach to a part of a breathing assistance apparatus and for locating the gas sampling end. The gas sampling end is to be located in a region where gas from the patient is to be exhaled. The gas sampling end being in communication with a sensor comprising a detector material changeable between a first visual indicator state relating to an inhalation phase of the patient, and a second visual indicator state relating to an exhalation phase of the patient. The detector material is capable of changing between the visual indicator states at a sufficient rate to substantially correspond with the inhalation and exhalation phases of the patient.

Abstract: Devices, systems, and methods are provided for performing volume and intensity-based activity evaluations. A method may include determining, by a device, a heart rate. The method may include determining, based on the heart rate, a motion threshold amount for a time period. The method may include determining motion data. The method may include comparing the motion data to the motion threshold for the time period. The method may include determining, based on the comparison of the motion data to the motion threshold for the time period, an activity intensity level associated with the heart rate and the motion data. The method may include determining, based on the activity intensity level, an activity score. The method may include sending data indicating the activity score for presentation at a second device.