Abstract: The present invention is directed to Benzomorphan Analog compounds of the Formula (I), Formula (IA), Formula (IB), Formula (IC), or Formula (ID) as shown below, wherein R1, R2a, R2b, R3, R4, Z, and G are as defined herein. Compounds of the Invention are useful for treating pain, constipation, and other conditions modulated by activity of opioid and ORL-1 receptors.

Abstract: User-specific language models (LMs) that include internal word indexes to a word table specific to the user-specific LM rather than a word table specific to a system-wide LM. When the system-wide LM is updated, the word table of the user-specific LM may be updated to translate the user-specific indices to system-wide indices. This prevents having to update the internal indices of the user-specific LM every time the system-wide LM is updated.

Abstract: A method and system for assigning data packet transmission in a wireless communications network is provided. The method comprises receiving first and second user data packets having respective first and second packet sizes, one of the packet sizes being larger than the other, determining an uplink/downlink ratio based on network statistics, and assigning the first and second data packets to respective first and second signal carrier spectrums each having a different time interval between uplink transmissions with the network. A system is also provided comprising a network controller configured to receive data packets and assign individual data packets to one of a first and a second signal carrier spectrum based on the size of the data packets, the first and the second signal carrier spectrums having the same uplink/downlink ratio and different uplink intervals.

Abstract: The invention provides systems, compositions, kits and methods for automated processing of biological samples and analysis using a flow cytometer.

Abstract: Systems and methods for detecting similar audio being received by separate voice activated electronic devices, and ignoring those commands, is described herein. In some embodiments, a voice activated electronic device may be activated by a wakeword that is output by the additional electronic device, such as a television or radio, may capture audio of sound subsequently following the wakeword, and may send audio data representing the sound to a backend system. Upon receipt, the backend system may, in parallel to performing automated speech recognition processing to the audio data, generate a sound profile of the audio data, and may compare that sound profile to sound profiles of recently received audio data and/or flagged sound profiles. If the generated sound profile is determined to match another sound profiles, then the automated speech recognition processing may be stopped, and the voice activated electronic device may be instructed to return to a keyword spotting mode.

Abstract: A method is disclosed in which control processes are used to maintain consistency across a research or diagnostic series of steps. Some embodiments of the processes include the use of fresh or lyophilized cell lines, beads, surface or other markers. The use of quality control processes is intended to monitor data from the underlying methods in order to detect unacceptable variations and to allow for exclusion or normalization. Overlapping control processes allows for tighter control and for redundancy in the monitoring.

Abstract: The present invention provides methods, compositions and kits for the characterization of cellular pathways in cells containing genetic alterations.

Abstract: The present disclosure relates to devices and methods of converting a bicycle frame from a mechanical gear-shifting configuration to an electronic gear-shifting configuration and vice versa. In a representative embodiment, a method of converting a bicycle frame from a mechanical gear-shifting configuration to an electronic gear-shifting configuration comprises removing a mechanical cable extending between a mechanical gear-shift actuator and a mechanical gear shifter via a cable stop of a removable bracket member secured to a down tube member of the bicycle frame, and removing the removable bracket member from the down tube member of the bicycle frame. The method further comprises mounting an electronically-actuated gear shifter to the bicycle frame in electrical communication with an electronic gear-shift actuator such that actuation of the electronic gear-shift actuator causes the electronically-actuated gear shifter to shift gears.

Abstract: In a dynamic automatic speech recognition (ASR) processing system, ASR processing may be configured to estimate a latency of returning speech results to a user based on work being done by an ASR processor. The ASR processing system may measure work done by an ASR processor by measuring one or more time independent metrics and comparing the metrics to threshold values. If the metrics exceed the thresholds, the ASR system may take steps to reduce latency associated with processing the utterance, including adjusting a speech recognition parameter.

Abstract: The present disclosure relates to devices and methods of converting a bicycle frame from a mechanical gear-shifting configuration to an electronic gear-shifting configuration and vice versa. In a representative embodiment, a method of converting a bicycle frame from a mechanical gear-shifting configuration to an electronic gear-shifting configuration comprises removing a mechanical cable extending between a mechanical gear-shift actuator and a mechanical gear shifter via a cable stop of a removable bracket member secured to a down tube member of the bicycle frame, and removing the removable bracket member from the down tube member of the bicycle frame. The method further comprises mounting an electronically-actuated gear shifter to the bicycle frame in electrical communication with an electronic gear-shift actuator such that actuation of the electronic gear-shift actuator causes the electronically-actuated gear shifter to shift gears.

Abstract: In an automatic speech recognition (ASR) processing system, ASR processing may be configured to reduce a latency of returning speech results to a user. The latency may be determined by comparing a time stamp of an utterance in process to a current time. Latency may also be estimated based on an endpoint of the utterance or other considerations such as how difficult the utterance may be to process. To improve latency the ASR system may be configured to adjust various processing parameters, such as graph pruning factors, path weights, ASR models, etc. Latency checks and corrections may occur dynamically for a particular utterance while it is being processed, thus allowing the ASR system to adjust to rapidly changing latency conditions.

Abstract: Compounds and methods in the fields of chemistry and medicine are disclosed. Some of the disclosed embodiments include compounds, compositions and methods of using heterocycle amines. Some of the disclosed embodiments include heterocycle amines useful to treat inflammatory disorders.

Abstract: Determining the end of an utterance for purposes of automatic speech recognition (ASR) may be improved with a system that provides early results and/or incorporates semantic tagging. Early ASR results of an incoming utterance may be prepared based at least in part on an estimated endpoint and processed by a natural language understanding (NLU) process while final results, based at least in part on a final endpoint, are determined. If the early results match the final results, the early NLU results are already prepared for early execution. The endpoint may also be determined based at least in part on the content of the utterance, as represented by semantic tagging output from ASR processing. If the tagging indicate completion of a logical statement, an endpoint may be declared, or a threshold for silent frames prior to declaring an endpoint may be adjusted.

Abstract: The present disclosure relates to devices and methods of converting a bicycle frame from a mechanical gear-shifting configuration to an electronic gear-shifting configuration and vice versa. In a representative embodiment, a method of converting a bicycle frame from a mechanical gear-shifting configuration to an electronic gear-shifting configuration comprises removing a mechanical cable extending between a mechanical gear-shift actuator and a mechanical gear shifter via a cable stop of a removable bracket member secured to a down tube member of the bicycle frame, and removing the removable bracket member from the down tube member of the bicycle frame. The method further comprises mounting an electronically-actuated gear shifter to the bicycle frame in electrical communication with an electronic gear-shift actuator such that actuation of the electronic gear-shift actuator causes the electronically-actuated gear shifter to shift gears.

Abstract: In systems and methods of managing wireless communication link resources, a static overhead load, a data traffic load, and a signaling load are determined of a wireless communication link between an access node and at least one wireless device. A wireless communication link load is calculated based on the static overhead load, the data traffic load, and the signaling load, and a load control process is performed when the wireless communication link load meets a load criteria.

Abstract: Features are disclosed for identifying and providing command suggestions during automatic speech recognition. As utterances are interpreted, suggestions may be provided based on even partial interpretations to guide users of a client device to commands available via speech recognition.

Abstract: Compounds and methods in the fields of chemistry and medicine are disclosed. Some of the disclosed embodiments include compounds, compositions and methods of using heterocycle amines. Some of the disclosed embodiments include heterocycle amines useful to treat inflammatory disorders.

Abstract: A wireless network access device comprising a radio interface with a serial communication line, a switch, and M serial connections to M connectors for connecting up to M corresponding detachable radio modules. The radio interface forms up to M individually addressable radio communications paths. Each radio module includes a radio configured to communicate with client devices in a coverage area and a radio processor configured to manage at least one radio receiving buffer. The radio receiving buffers store receiver buffer identifiers to corresponding received data space. A processor manages communication between the client devices that communicate with the radio modules and a data network via the radio interface and a network interface when N?M radio modules are connected to the radio interface. An assist engine is connected in the serial connection between the processor and the switch to manage allocation of receive buffer identifiers to the radio modules.

Abstract: The invention provides systems, compositions, kits and methods for automated processing of biological samples and analysis using a flow cytometer.

Abstract: The present invention is directed to Benzomorphan Analog compounds of the Formula (I), Formula (IA), Formula (IB), Formula (IC), or Formula (ID) as shown below, wherein R1, R2a, R2b, R3, R4, Z, and G are as defined herein. Compounds of the Invention are useful for treating pain, constipation, and other conditions modulated by activity of opioid and ORL-1 receptors.