Patents by Inventor David Sinclair

David Sinclair has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20260119278
    Abstract: In accordance with the described techniques, a system includes a plurality of compute nodes including a management node and a plurality of execution nodes. A processor of the management node is configured to read efficiency metrics associated with respective execution nodes of the plurality of execution nodes from one or more registers of the management node. Based on the efficiency metrics, the processor distributes software processes among the plurality of execution nodes for execution.
    Type: Application
    Filed: October 31, 2024
    Publication date: April 30, 2026
    Applicant: Advanced Micro Devices, Inc.
    Inventors: Srilatha Manne, Rajagopalan Desikan, Heather Lynn Hanson, Shidhartha Das, David Sinclair
  • Publication number: 20240197617
    Abstract: An anti-aging cosmetic composition including resveratrol and/or a derivative of resveratrol in combination with honokiol and/or magnolol. These molecules can be obtained from plant extracts. Both honokiol and magnolol are present in magnolia bark. A cosmetic treatment method is related including the application to the skin or skin appendages of the cosmetic composition.
    Type: Application
    Filed: May 10, 2022
    Publication date: June 20, 2024
    Inventors: Mathilde THOMAS, Bertrand THOMAS, David SINCLAIR
  • Publication number: 20240132872
    Abstract: Provided herein are methods and compositions for the capture of nucleic acids, for example by using a nucleic acid-guided nuclease-based system.
    Type: Application
    Filed: February 1, 2023
    Publication date: April 25, 2024
    Inventors: Stephane B. GOURGUECHON, Eric HARNESS, David SINCLAIR, Meredith L. CARPENTER
  • Publication number: 20200087652
    Abstract: Provided herein are methods and compositions for the capture of nucleic acids, for example by using a nucleic acid-guided nuclease-based system.
    Type: Application
    Filed: December 2, 2019
    Publication date: March 19, 2020
    Inventors: Stephane B. GOURGUECHON, Eric HARNESS, David SINCLAIR, Meredith L. CARPENTER
  • Publication number: 20200046617
    Abstract: The invention relates to a cosmetic use of an association of (i) resveratrol or a derivative thereof and (ii) betaine or a derivative thereof, or of a composition containing said association in a physiologically acceptable medium, to fight against the signs of ageing of the skin.
    Type: Application
    Filed: April 24, 2017
    Publication date: February 13, 2020
    Inventors: Mathilde Thomas, Bertrand Thomas, David Sinclair
  • Patent number: 10538758
    Abstract: Provided herein are methods and compositions for the capture of nucleic acids, for example by using a nucleic acid-guided nuclease-based system.
    Type: Grant
    Filed: August 18, 2016
    Date of Patent: January 21, 2020
    Assignee: Arc Bio, LLC
    Inventors: Stephane B. Gourguechon, Eric Harness, David Sinclair, Meredith L. Carpenter
  • Patent number: 10470987
    Abstract: Compositions allowing the stimulation of hyaluronic acid synthesis via an increase in has-2 expression and their use in the treatment of conditions related to a decrease in hyaluronic acid synthesis.
    Type: Grant
    Filed: June 5, 2015
    Date of Patent: November 12, 2019
    Assignees: TOMCAT INTERNATIONAL LIMITED, President and Fellows of Harvard College
    Inventors: Bertrand Thomas, Mathilde Thomas, David Sinclair
  • Patent number: 10229215
    Abstract: A method of rendering content items on a display via an electronic device involves mapping linked content items to a three-dimensional object defined by layout data. The layout data is then transmitted to an electronic device for display.
    Type: Grant
    Filed: September 26, 2016
    Date of Patent: March 12, 2019
    Assignees: DISNEY ENTERPRISES, INC., ETH ZÜRICH (EIDGENÖSSISCHE TECHNISCHE HOCHSCHULZE ZÜRICH)
    Inventors: Barbara Solenthaler, Sohyeon Jeong, Max Grosse, Sasha Schriber, David Sinclair, Maria Cabral, Markus Gross, Kenneth J. Mitchell
  • Publication number: 20180312830
    Abstract: Provided herein are methods and compositions for the capture of nucleic acids, for example by using a nucleic acid-guided nuclease-based system.
    Type: Application
    Filed: August 18, 2016
    Publication date: November 1, 2018
    Applicant: Arc Bio, LLC
    Inventors: Stephane B. GOURGUECHON, Eric HARNESS, David SINCLAIR, Meredith L. CARPENTER
  • Publication number: 20180161256
    Abstract: Compositions allowing the stimulation of hyaluronic acid synthesis via an increase in has-2 expression and their use in the treatment of conditions related to a decrease in hyaluronic acid synthesis.
    Type: Application
    Filed: June 5, 2015
    Publication date: June 14, 2018
    Inventors: Bertrand THOMAS, Mathilde THOMAS, David SINCLAIR
  • Publication number: 20180089905
    Abstract: A method of rendering content items on a display via an electronic device involves mapping linked content items to a three-dimensional object defined by layout data. The layout data is then transmitted to an electronic device for display.
    Type: Application
    Filed: September 26, 2016
    Publication date: March 29, 2018
    Applicants: Disney Enterprises, Inc., ETH Zürich (Eidgenössische Technische Hochschule Zürich)
    Inventors: Barbara Solenthaler, Sohyeon Jeong, Max Grosse, Sasha Schriber, David Sinclair, Maria Cabral, Markus Gross, Kenneth J. Mitchell
  • Publication number: 20150175645
    Abstract: Provided herein are sirtuin-modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing. Also provided are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent.
    Type: Application
    Filed: July 24, 2014
    Publication date: June 25, 2015
    Inventors: Michael MILBURN, Jill MILNE, Karl D. NORMINGTON, Joseph J. NUNES, Thomas SALZMANN, David SINCLAIR, Christoph H. WESTPHAL
  • Publication number: 20140067856
    Abstract: Systems and methods for facilitating diagnosis and product identification for patients requiring continence products. Embodiments of the invention have been particularly developed there by to provide a software application (for example an iOS or Android application) thereby to assist a clinician and/or patient in identifying appropriate continence products for a given set of patient requirements. While some embodiments will be described herein with particular reference to that application, it will be appreciated that the invention is not limited to such a field of use, and is applicable in broader contexts.
    Type: Application
    Filed: September 5, 2013
    Publication date: March 6, 2014
    Inventors: Kylie Wicks, David Sinclair, Birgitte Maibom, Elke Krishnan
  • Publication number: 20130273498
    Abstract: A dental implant comprising an implant body which has an asymmetric root portion receivable in an asymmetric open root cavity of the patient and engagement means on the asymmetric root portion to at least in part engage a surface of the root cavity so as to prevent or inhibit unintentional extraction. The asymmetric root portion is complementarily shaped to fit the said asymmetric open root cavity, thus substantially dispensing with the need for protracted preparation of the root cavity and providing substantially immediate stability for the prosthetic tooth.
    Type: Application
    Filed: November 1, 2011
    Publication date: October 17, 2013
    Inventors: John Woods, Michael Tuke, David Sinclair
  • Publication number: 20110159464
    Abstract: A spherical object is disclosed provided with a map substantial covering its entire surface wherein the map represents only a portion of the Earth such as a town, city, district, county, state or country. A label is also disclosed provided comprising a series of biconvex shapes which collectively describe such a map.
    Type: Application
    Filed: December 31, 2009
    Publication date: June 30, 2011
    Applicant: GLOBEE LIMITED
    Inventor: David Sinclair
  • Publication number: 20100065469
    Abstract: The determination of wax crystal particle size and population is used to monitor the performance of wax crystallizers used in lubricant oil processing using solvent dewaxing. The wax crystal particle size is monitored using online measurements. The information obtained from on-line monitoring is then used to control crystallization in the dewaxing equipment in order to optimize performance of the dewaxing units.
    Type: Application
    Filed: October 19, 2007
    Publication date: March 18, 2010
    Inventors: Thomas R. Palmer, Brent E. Beasley, David Sinclair
  • Publication number: 20070230801
    Abstract: A technique is provided for classifying images in a library (1) for subsequent selective retrieval. Each library image is segmented (2) into a plurality of coherent regions. Each of the regions is analysed in respect of a plurality of visual properties, each of which is ascribed a number according to the value of the visual property. The property numbers are then compared (4) with bands of the available property range and a computer-readable character, such as a letter of the alphabet, is ascribed to each of the property values. The characters are then arranged (5) in a predetermined order to form a region character string. The strings for each region are then indexed (7) to form an index (8) of the images by region character string. For image retrieval, a target image (10) is analysed in the same way to form region character strings which are then supplied to a text retrieval system (12) for detecting matches with entries in the index (8).
    Type: Application
    Filed: June 8, 2007
    Publication date: October 4, 2007
    Inventors: David Sinclair, Kenneth Wood
  • Publication number: 20060276416
    Abstract: Provided herein are methods and compositions for treating and/or preventing flushing and/or weight gain. Methods may comprise modulating the activity or level of a sirtuin, such as SIRT1 or Sir2. Exemplary embodiments include methods and compositions for counteracting drug-induced weight gain and/or drug-induced flushing by administering a sirtuin-activating compound.
    Type: Application
    Filed: January 20, 2006
    Publication date: December 7, 2006
    Applicant: Sirtris Pharmaceuticals, Inc.
    Inventors: David Sinclair, Robert Langer, Christoph Westphal, Michael Milburn
  • Publication number: 20060229265
    Abstract: Provided herein are sirtuin-modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing. Also provided are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent.
    Type: Application
    Filed: March 30, 2006
    Publication date: October 12, 2006
    Applicant: Sirtris Pharmaceuticals, Inc.
    Inventors: Michael Milburn, Jill Milne, Karl Normington, Joseph Nunes, Thomas Salzmann, David Sinclair, Christoph Westphal
  • Patent number: D683792
    Type: Grant
    Filed: October 26, 2009
    Date of Patent: June 4, 2013
    Assignee: Globee Limited
    Inventor: David Sinclair