Abstract: This invention relates to methods of characterising mammalian cells, e.g. mammalian cancer cells, based on their chemotypic signature. The methods comprise contacting test mammalian cells with a panel of reference compounds, measuring the effect of each reference compound on a phenotypic property of the test mammalian cells to produce a score for each reference compound in the panel, combining the scores to produce a chemotypic signature, and comparing this signature to the signatures of a set of reference mammalian cell lines. This may be useful for diagnostic and prognostic applications, as well as rational drug design, patient stratification, and personalised drug discovery.

Abstract: Vehicles for use on a railway and their methods of operation are disclosed. In one embodiment, a vehicle includes a bogie with wheels engaged with opposing tracks extending along a length of a railway the bogie travels along. The vehicle includes at least one sensor configured to sense a position of the bogie and/or wheels relative to the tracks of the railway. A processor of the vehicle uses the sensed position of the bogie and/or wheels relative to the tracks to steer the wheels of the bogie along a desired path on the tracks as the bogie travels along the railway.

Abstract: Embodiments related to a rail system for use with a personal rapid transit system are disclosed. In some embodiments, a railway may include a first rail configured to engage and support a bogie of a vehicle and a lift rail may be configured to engage and support the bogie of the vehicle. The lift rail, which may be a lift arm including a short section of rail that is attached at one end to a lift, may be configured to change a position of the lift rail to transition the vehicle between different desired positions. In another embodiment, a railway may include a first pair of main rails intersecting a second pair of main rails, where the second pair of main rails are divided by the first pair of main rails and a portion of the second pair of main rails are configured to hold one or more stationary vehicles.

Abstract: The present invention is for an improved vertical flow reactor utility that makes the technology more attractive for industrial development. The various embodiments of the invention improve various aspects of a vertical flow reactor utility. For example, in accordance with an embodiment of the invention, the design of the reactor is improved. Other embodiments provide improved systems and methods for, for example, insertion of oxygen, electrical production, and/or reactor geometry. These one or more various embodiments of the present invention lowers costs to construct, install, and/or operate a vertical flow reactor by improving economy of construction and/or operation of VFR systems.

Abstract: Proofing computer code in code blocks of an electronic computing interface based on generated dependency information between at least some related code blocks. When executing one or more of the code blocks, the dependency information is generated which tracks one or more of information associated with a user's actions, defined variables, defined functions, called functions, and associated imported data. A notification is displayed in the electronic computing interface to indicate when one or more or inconsistencies exist between related code blocks based on the dependency information.

Abstract: A self-contained active thermal regulating device includes a flexible, deformable outer membrane; a liquid saturated foam core contained therein having a dimension substantially coincident with the outer membrane wherein the liquid is at least partially circulable throughout the foam core; and, a phase change material being in intimate contact with the circulable liquid. The circulation of the liquid is effective to transfer heat between the flexible, deformable outer membrane and the phase change material to cool (or heat) the device without use of external power and the saturated foam core in cooperation with the sealable flexible membrane providing a substantially uniform, thermal regulating medium and structural support such that the device is readily, uniformly deformable when a load is applied thereto.

Abstract: Methods for providing skin enhancement and pain relief to an individual in need of treatment by administering to such an individual an effective amount of an immunostimulatory Aloe vera derived composition. Oral and topical methods and compositions are provided. Aloe vera derived immunostimulatory compositions and methods of producing such compositions are provided.

Abstract: Methods for providing skin enhancement and pain relief to an individual in need of treatment by administering to such an individual an effective amount of an immunostimulatory Aloe vera derived composition. Oral and topical methods and compositions are provided. Aloe vera derived immunostimulatory compositions and methods of producing such compositions are provided.

Abstract: The disclosure relates to systems, software and methods for diagnosis or prognosis of subjects for dementia, including, classification and treatment of subjects who have been diagnosed with or deemed at risk of dementia. The methods are based, in part, on the multimodal analysis of a plurality of features, e.g., genetic features such as SNPs or chromosome regions, including, loci or genes related thereto and structural brain features such as MRI images of brain or brain regions.

Abstract: Processes for producing melamine octamolybdates having high thermal stability include a step of reacting molybdenum trioxide and melamine in an acidic aqueous system at a pH of less than or equal to about 4 to form a slurry of the melamine octamolybdate. The resulting melamine octamolybdate can be characterized by a decomposition onset temperature (or a temperature at a weight loss of 1%, or a temperature at a weight loss of 2%) on a thermogravimetric analysis curve of greater than 300° C., and is useful in polymer compositions as a smoke suppressant.

Abstract: Processes for producing melamine octamolybdates having high thermal stability include a step of reacting molybdenum trioxide and melamine in an acidic aqueous system at a pH of less than or equal to about 4 to form a slurry of the melamine octamolybdate. The resulting melamine octamolybdate can be characterized by a decomposition onset temperature (or a temperature at a weight loss of 1%, or a temperature at a weight loss of 2%) on a thermogravimetric analysis curve of greater than 300° C., and is useful in polymer compositions as a smoke suppressant.

Abstract: An ultrasonic cleaning apparatus comprising: a tank for in use receiving a cleaning liquid and an item to be cleaned; a plurality of transducers arranged, when driven, to direct ultrasonic pressure waves into the tank; and a controller arranged in use to drive the transducers. First and second transducers from the plurality of transducers are arranged in use to direct ultrasonic pressure waves into an overlapping volume; and the controller is arranged in use to drive the first and second transducers to produce ultrasonic pressure waves at different frequencies from each other. The controller is arranged to in use produce first and second drive signals for the transducers using first and second frequency generators to each switch between primary and secondary operation, with the sequential switching taking place to cause different combinations of primary and secondary operation for the first and second frequency generators to occur over time.

Abstract: A head restraint system having a rate sensitive device to connect a head restraint to a body of a user. The head restraint system includes a first connector to connect to the head of a user, a second connector connected to the first connector and to a body of the user, wherein one of the first connector and the second connector includes a rate sensitive (RS) device, wherein the first connector and the second connector are configured to restrain the user's head to the user's body at high speed motion of the user's head relative to the user's body and otherwise not restrain the user's head.

Abstract: A system measures the stability of a live a.c. power distribution grid, without disrupting sensitive loads on that grid. The system applies repetitive time-synchronized loads to create current pulses, and resulting voltage instabilities, on the grid. The current pulses are sized to ensure that the resulting voltage instabilities are too small to affect the sensitive loads. Time-synchronized voltage measurement devices record the voltage instabilities. The time synchronization, and the repetitive nature of the current pulses, allow the voltage instabilities caused by the current pulses to be extracted from the larger background voltage variations.

Abstract: Processes for producing melamine octamolybdates having high thermal stability include a step of reacting molybdenum trioxide and melamine in an acidic aqueous system at a pH of less than or equal to about 4 to form a slurry of the melamine octamolybdate. The resulting melamine octamolybdate can be characterized by a decomposition onset temperature (or a temperature at a weight loss of 1%, or a temperature at a weight loss of 2%) on a thermogravimetric analysis curve of greater than 300° C., and is useful in polymer compositions as a smoke suppressant.

Abstract: An ultrasonic cleaning apparatus and method, the ultrasonic cleaning apparatus (10) comprising a tank (12) for in use receiving a cleaning liquid and for receiving an item to be cleaned in a cleaning region (16) thereof, a transducer (21) arranged, when driven, to direct ultrasonic pressure waves into cleaning liquid received in the tank (12) and a controller (30) arranged in use to drive the transducer (21), a gas introducer (40) arranged to in use provide a supply of gas into cleaning liquid in the tank so that macroscopic bubbles of gas are produced wherein the gas introducer (40) provides a plurality of bubble sources distributed below the cleaning region of the tank. The apparatus further comprises an assembly arranged in use to enable movement of the item to be cleaned in the cleaning region.

Abstract: A method of accessing a persistent memory over a memory interface is disclosed. In one embodiment, the method includes allocating a virtual address range comprising virtual memory pages to be associated with physical pages of a memory buffer and marking each page table entry associated with the virtual address range as not having a corresponding one of the physical pages of the memory buffer. The method further includes generating a page fault when one or more of the virtual memory pages within the virtual address range is accessed and mapping page table entries of the virtual memory pages to the physical pages of the memory buffer. The method further includes transferring data between a physical page of the persistent memory and one of the physical pages of the memory buffer mapped to a corresponding one of the virtual memory pages.

Abstract: A method of accessing a persistent memory over a memory interface is disclosed. In one embodiment, the method includes allocating a virtual address range comprising virtual memory pages to be associated with physical pages of a memory buffer and marking each page table entry associated with the virtual address range as not having a corresponding one of the physical pages of the memory buffer. The method further includes generating a page fault when one or more of the virtual memory pages within the virtual address range is accessed and mapping page table entries of the virtual memory pages to the physical pages of the memory buffer. The method further includes transferring data between a physical page of the persistent memory and one of the physical pages of the memory buffer mapped to a corresponding one of the virtual memory pages.

Abstract: A flushing system for boat motors that allows for single-handed manipulation to remotely position flushing ears onto the intake vents of an outboard boat motor. A water passage tube provides a source of fresh water when flushing or performing maintenance on the motor of a boat stored on a lift. The flushing ears are positioned on the intake valves and are adjusted to form a seal by a gripping handle. A locking device prevents movement of the ears while flushing the motor and can be released to remove the ears once the flushing is complete.

Abstract: There are disclosed impedance matching networks and technique for impedance matching to microwave power transistors. Distributed capacitor inductor networks are used so as to provide a high degree of control and accuracy, especially in terms of inductance values, in comparison to existing lumped capacitor arrangements. The use of bond wires is reduced, with inductance being provided primarily by microstrip transmission lines on the capacitors.