Abstract: A fill level control system for an article cleaning apparatus is provided. The fill level control system uses a sensor array to monitor a plurality of fill level points within, for example, a dishwasher. The level of water for each wash phase is monitored as a function of its height above the sump of an article cleaning apparatus, and the liquid used in the washing apparatus is introduced as a function of signals produced giving the level of liquid. The fill level control system further includes a low level sensor that turns the pumping system for the article cleaning apparatus off when the sump portion has been completely emptied. A further aspect of the fill level control system is an optional temperature control sensor, integrated with the liquid level sensors, to provide signals for modifying the temperature within the article cleaning apparatus.

Abstract: The present invention is directed to methods and compositions for evaluating allelic variations with improved quality controls, methods of preparing such compositions, and applications employing such compositions and methods. In particular, the present invention provides methods and compositions for reducing false positives and/or false negatives in nucleic acid measurements.

Abstract: The present invention identifies and quantifies changes in gene expression associated with non-small cell lung cancer NSCLC by examining gene expression in tissue from normal lung and diseased lung. The present invention also identifies and quantifies expression profiles which serve as useful diagnostic markers as well as markers that are useful to monitor disease states, disease progression, drug toxicity, drug efficacy and drug metabolism.

Abstract: A storage rack comprises horizontally extending front and back beams having upper surfaces, on which is supported a roller track comprising two side rails, a series of rollers journalled between and projecting above the side rails, and a series of tie rods extending between and bracing the side rails. The roller track is secured to the front and back beams by a front clip embracing an underside of the front beam, a J-bolt connected to the front clip and hooked over a front one of the tie rods, a back clip embracing an underside of the back beam, and a J-bolt connected to the back clip and hooked over a back one of the tie rods.

Abstract: The present invention provides compounds that inhibit Factor XIa and methods of preventing or treating undesired thrombosis by administering a compound of the invention to a mammal. The invention also provides three-dimensional structures of Factor XIa and methods for designing or selecting additional Factor XIa inhibitors using these structures.

Abstract: Automatic energy management is provided, in even the most complex multi-building system. The necessity of a human operator for managing energy in a complex, multi-building system is reduced and even eliminated. Computer-based monitoring and computer-based recognition of adverse energy events (such as the approach of a new energy peak) is highly advantageous in energy management. Immediate automatic querying of energy users within a system of buildings for energy curtailment possibilities is provided. Such immediate, automatic querying may be answered by the energy users through artificial intelligence and/or neural network technology provided to or programmed into the energy users, and the queried energy users may respond in real-time. Those real-time computerized responses with energy curtailment possibilities may be received automatically by a data processing facility, and processed in real-time.

Abstract: Automatic energy management is provided, in even the most complex multi-building system. The necessity of a human operator for managing energy in a complex, multi-building system is reduced and even eliminated. Computer-based monitoring and computer-based recognition of adverse energy events (such as the approach of a new energy peak) is highly advantageous in energy management. Immediate automatic querying of energy users within a system of buildings for energy curtailment possibilities is provided. Such immediate, automatic querying may be answered by the energy users through artificial intelligence and/or neural network technology provided to or programmed into the energy users, and the queried energy users may respond in real-time. Those real-time computerized responses with energy curtailment possibilities may be received automatically by a data processing facility, and processed in real-time.

Abstract: In a releasable locking device, which is useful at a beam-to-column connection in a storage rack, a housing having a lateral wall with two parallel slots has an end wall at an outer end and is open at the inner end, a locking pin having an internal portion movable within and along the lateral wall is movable between a retracted position and an extended position, toward which the locking pin is biased, and an outer sleeve is movable outside and along the lateral wall of the housing and is connected to the locking pin via a connecting pin extending through the locking pin, through the parallel slots, at each end to the outer sleeve. The outer sleeve has an external flange to facilitate pulling of the outer sleeve to move the locking pin toward the retracted position.

Abstract: A method measure expression of multiple target genes in a progenitor cell for bronchogenic carcinoma comprising the use of reverse transcription-polymerase chain reaction (RT-PCR) to allow simultaneous expression measurement of the multiple target genes is disclosed.

Abstract: In a releasable locking device, which is useful at a beam-to-column connection in a storage rack, a housing having a lateral wall with two parallel slots has an end wall at an outer end and is open at the inner end, a locking pin having an internal portion movable within and along the lateral wall is movable between a retracted position and an extended position, toward which the locking pin is biased, and an outer sleeve is movable outside and along the lateral wall of the housing and is connected to the locking pin via a connecting pin extending through the locking pin, through the parallel slots, at each end to the outer sleeve. The outer sleeve has an external flange to facilitate pulling of the outer sleeve to move the locking pin toward the retracted position.

Abstract: A storage rack comprises horizontally extending front and back beams having upper surfaces, on which is supported a roller track comprising two side rails, a series of rollers journalled between and projecting above the side rails, and a series of tie rods extending between and bracing the side rails. The roller track is secured to the front and back beams by a front clip embracing an underside of the front beam, a J-bolt connected to the front clip and hooked over a front one of the tie rods, a back clip embracing an underside of the back beam, and a J-bolt connected to the back clip and hooked over a back one of the tie rods.

Abstract: In a releasable locking device, which is useful at a beam-to-column connection in a storage rack, a housing having a lateral wall with two parallel slots has an end wall at an outer end and is open at the inner end, a locking pin having an internal portion movable within and along the lateral wall is movable between a retracted position and an extended position, toward which the locking pin is biased, and an outer sleeve is movable outside and along the lateral wall of the housing and is connected to the locking pin via a connecting pin extending through the locking pin, through the parallel slots, at each end to the outer sleeve. The outer sleeve has an external flange to facilitate pulling of the outer sleeve to move the locking pin toward the retracted position.

Abstract: Automatic energy management is provided, in even the most complex multi-building system. The necessity of a human operator for managing energy in a complex, multi-building system is reduced and even eliminated. Computer-based monitoring and computer-based recognition of adverse energy events (such as the approach of a new energy peak) is highly advantageous in energy management. Immediate automatic querying of energy users within a system of buildings for energy curtailment possibilities is provided. Such immediate, automatic querying may be answered by the energy users through artificial intelligence and/or neural network technology provided to or programmed into the energy users, and the queried energy users may respond in real-time. Those real-time computerized responses with energy curtailment possibilities may be received automatically by a data processing facility, and processed in real-time.

Abstract: A method of automatically conducting patch clamp testing is provided wherein a liquid interface is utilized. The liquid interface is defined in a liquid suspension between layers of distinct densities such that cells introduced into the liquid suspension float towards the interface. Thus, the cells are locatable relative to the interface.

Abstract: The present application is directed to pipette configurations, arrays of the same and methods for using such pipettes and arrays to accomplish electrical measurements, including whole cell and on cell measurements. In one aspect of the present invention, a pipette includes a hollow tubular section having a distal portion and a tip portion. A bubble is formed at the tip and includes an interior chamber in communication with the hollow tubular section at an end adjacent to the bubble portion. The bubble may have a diameter greater than the diameter of an adjacent portion of the hollow tubular section. An aperture is formed between the internal chamber and an exterior surface of the bubble to accommodate seal formation.

Abstract: Methods and systems for loading and receiving traffic from a broadband communication link, such as an OC-3, link are disclosed. A system for loading a broadband communication link includes a simulated traffic generator for generating simulated traffic to be sent over the broadband communication link. Cascadable processing modules receive and aggregate the simulated traffic to load a broadband communication link. The cascadable processing modules can also receive and process data from a broadband communication link. Each cascadable processing module filters and processes a portion of received traffic. A single platform can be configured to simultaneously load a broadband communication link and receive traffic from the broadband communication link.

Abstract: Novel thallium-sensitive assays for identifying modulators of ion channels, channel-linked receptors or ion transporters are provided. The invention further provides novel chloride-free buffers and low chloride cell growth media.

Abstract: The present invention provides a method for generating and isolating cell lines that functionally express molecular targets for drug discovery without utilizing information from the nucleic acid or amino acid sequence of the target protein. This procedure for the first time allows one to develop fast, high throughput screens for evaluation of test compounds that may modulate molecular targets whose specific nucleic acid or amino acid sequences are unavailable.

Abstract: The present invention provides apparatuses for measuring cell membrane resistance, conductance, potential, and capacitance, which can be used to determine cellular electrical activity. More specifically, the present invention provides automated apparatuses that are designed for high-throughput analysis of various compounds, ligands, and cell processes that modulate cellular electrical properties (e.g., cell membrane conditions). Such automated apparatuses can be used for the precise determination of ion channel activity, and for the rapid identification of compounds, ligands, or processes that alter this activity. The present invention also provides methods for measuring cellular electrical properties utilizing the apparatuses provided herein.

Abstract: A method and apparatus for quantitative measurement of gene expression through multiplex competitive reverse transcriptase polymerase chain reaction amplification are disclosed. The method and apparatus are especially useful for analysis of small specimens of cells and tissues.