Abstract: The present invention provides pharmaceutical compositions comprising solid nanoparticles, wherein the solid nanoparticles comprise i) an effective amount of a therapeutically active agent, wherein the therapeutically active agent is a substantially water insoluble prodrug; and ii) a biocompatible polymer.

Abstract: Systems, methods, and devices that perform flow scan sequences are provided. In one embodiment, an ultrasound imaging system includes an intraluminal catheter or guidewire, an annular array of acoustic elements positioned around a circumference of the catheter or guidewire, and a processor in communication with the annular array. The processor is configured to activate a first subaperture of the annular array at a first time, thereafter, activate a second interleaving subaperture, and activate the first subaperture again at a different, second time such that the scan sequence moves around the circumference of the catheter or guidewire. Temporal differences between the received ultrasound signals obtained by the first subaperture at the first and second times are determined to detect motion around the annular array. By interleaving subaperture firings, the total number of firings to form an image frame can be reduced.

Abstract: Disclosed herein are topical pharmaceutical compositions of Sebacoyl Dinalbuphine Ester (SDE) and methods of using such compositions for treating pruritus, pain, and inflammatory conditions.

Abstract: The present disclosure describes a flow reversing valve, along with associated methods and systems for providing forward flow, reverse flow, and bypass flow modes of operation, and integrating them into patient treatment systems, including those used for treating and inducing hyperthermia.

Abstract: Apparatuses, systems, and techniques to cause usage of information by a computer program to be increased based, at least in part, on one or more data structures used to monitor use of the information. In at least one embodiment, usage of information by a computer program is caused to be increased based, at least in part, on one or more data structures used to monitor use of the information based on, for example, CUDA or other parallel computing platform code.

Abstract: Apparatuses, systems, and techniques to generate one or more data structures to be used to monitor use of information by a computer program. In at least one embodiment, one or more data structures to be used to monitor use of information by a computer program are generated, based on, for example, CUDA or other parallel computing platform code.

Abstract: Apparatuses, systems, and techniques to cause usage of information by a computer program to be reduced based, at least in part, on one or more data structures used to monitor use of the information. In at least one embodiment, usage of information by a computer program is caused to be reduced based, at least in part, on one or more data structures used to monitor use of the information based on, for example, CUDA or other parallel computing platform code.

Abstract: A system and methods for ghost imaging second harmonic generation microscopy. Imaging data is collected in parallel, providing faster imagine reconstruction and enabling reconstruction in scattering environments. Ghost imaging, split light beam interacting with a target and a second light beam unimpeded and not required to pass through the same background. A second harmonic generation image is reconstructed from the detected photons.

Abstract: Rack-type backlight light emitting element (LEE) printed circuit boards (PCBs) with at least two layers to provide redundant current paths. This enables a PCB strip to be broken at designated perforations in the field in order to accommodate pipes or fixtures that require formation of a gap in the rack array. The entire length and width of an array can be sized in the field. A plurality of PCB arrays can be serially chained together with the system. A chain of PCB strips is snapped into clips, which in turn snap into rails that are fastened to a surface. The mounting system includes various types of clips, such as end clips, clips for different LEE patterns on the PCBs, and mounting clips to secure the rails to a surface.

Abstract: Methods and systems provide synchronized sharing of multimedia between multiple devices. The multiple devices may form an ad-hoc network for sharing of multimedia. In an embodiment, group members may have playlist manipulation privileges such as pausing, rewinding, fast forwarding, or adding tracks to the playlist. A system may stream or distribute content according to the shared playlist. Playback may be synchronized for group members so that everyone is exposed to a same part of the content as the same time.

Abstract: Systems, methods, and devices that perform flow scan sequences are provided. In one embodiment, an ultrasound imaging system includes an intraluminal catheter or guidewire, an annular array of acoustic elements positioned around a circumference of the catheter or guidewire, and a processor in communication with the annular array. The processor is configured to activate a first subaperture of the annular array at a first time, thereafter, activate a second interleaving subaperture, and activate the first subaperture again at a different, second time such that the scan sequence moves around the circumference of the catheter or guidewire. Temporal differences between the received ultrasound signals obtained by the first subaperture at the first and second times are determined to detect motion around the annular array. By interleaving subaperture firings, the total number of firings to form an image frame can be reduced.

Abstract: Hydrophilic, high quantum yield, chemiluminescent acridinium compounds with increased light output, improved stability, fast light emission and decreased non specific binding are disclosed. The chemiluminescent acridinium esters possess hydrophilic, branched, electron-donating functional groups at the C2 and/or C7 positions of the acridinium nucleus.

Abstract: Embodiments discussed herein facilitate employing a pretrained model to determine risk(s) of adverse event(s) based on Computed Tomography (CT) image volume(s) of an artery and/or training a model to determine such risk(s). Example embodiments can determine risk based on territory-specific calcium score(s) and/or intensity/morphological/location features discussed herein. Various embodiments can determine risk(s) based on a single CT image volume and/or change(s) in CT image volumes taken over a series of time points.

Abstract: The present invention provides a composition comprising solid nanoparticles wherein the solid nanoparticles comprise i) an effective amount of a first therapeutically active agent; ii) an effective amount of one or more additional therapeutically active agents; and iii) a biocompatible polymer wherein the one or more additional therapeutically active agents is sufficiently miscible with the first therapeutically active agent to form solid particles, wherein the particles comprise a substantially single-phase mixture of the first therapeutically active agent and the one or more additional therapeutically active agents.

Abstract: Hydrophilic, high quantum yield, chemiluminescent acridinium compounds with increased light output, improved stability, fast light emission and decreased non specific binding are disclosed. The chemiluminescent acridinium esters possess hydrophilic, branched, electron-donating functional groups at the C2 and/or C7 positions of the acridinium nucleus.

Abstract: A seam structure of protective clothing that is capable of being formed quickly and has high sealing performance provided includes: a first cloth including a first side surface and a second side surface opposite to each other; a second cloth welded to the first cloth and including a first surface and a second surface opposite to each other, wherein the first surface is abutted against and welded to the first side surface to form a first welding portion; a sealing cloth including a first sealing section and a third sealing section, wherein the first sealing section is abutted against and welded to the second side surface of the first cloth to form a second welding portion, and the third sealing section is abutted against and welded to the second surface of the second cloth to form a fourth welding portion.

Abstract: The present invention relates to methods of enhancing chemiluminescence from a chemiluminescent label comprising contacting a chemiluminescent label with an acid in the presence of a degradable cationic surfactant and hydrogen peroxide followed by the addition of a base. Related kits containing such degradable cationic surfactant are also provided. The degradable cationic surfactant can compress light emission time of the chemiluminescent label to an extent that is comparable to or shorter than conventional surfactants. The degradable cationic surfactant can also increase chemiluminescence of the chemiluminescent label, providing increased light emission output that is comparable to conventional surfactants.

Abstract: Zwitterion-containing compounds for the modification of hydrophobic molecules to improve their solubility and/or to lower their non-specific binding as provided. The zwitterion-containing compounds may be suitable for modification of detectable labels such as biotin and fluorescein to improve their solubility. The zwitterion-containing compounds may also be useful for the preparation of conjugates of proteins, peptides and other macromolecules or for crosslinking molecules and/or macromolecules.

Abstract: Hydrophilic, high quantum yield, chemiluminescent acridinium compounds with increased light output, improved stability, fast light emission and decreased non specific binding are disclosed. The chemiluminescent acridinium esters possess hydrophilic, branched, electron-donating functional groups at the C2 and/or C7 positions of the acridinium nucleus.

Abstract: The present invention relates to methods of enhancing chemiluminescence from a chemiluminescent label comprising contacting a chemiluminescent label with an acid in the presence of a degradable cationic surfactant and hydrogen peroxide followed by the addition of a base. Related kits containing such degradable cationic surfactant are also provided. The degradable cationic surfactant can compress light emission time of the chemiluminescent label to an extent that is comparable to or shorter than conventional surfactants. The degradable cationic surfactant can also increase chemiluminescence of the chemiluminescent label, providing increased light emission output that is comparable to conventional surfactants.