Abstract: A method for processing a sound program by a playback system, in which a virtual center channel is extracted from the sound program and a dynamic range compression and a boost are applied to produce a compressed virtual center channel. This is then used to produce a speaker driver signal. Other aspects are also described and claimed.

Abstract: Hardened reusable shipping containers (e.g., shippers) are disclosed herein. A shipper may have a base enclosure that is configured to receive a payload and maintain a temperature of an environment surrounding the payload. The shipper may have various features such as bosses, compartments, and surface features to facilitate protection of a dewar inside the base enclosure, and retention of a payload during shipment. The shipper may have various features to facilitate ready stacking of shippers and suitability for use in air cargo operations.

Abstract: A blower apparatus includes a fan and motor generating an airflow from an inlet end to an outlet end of the debris blower. The airflow defines an airflow axis and a cross-sectional plane normal to the airflow axis. An enclosure provides an airflow path towards the outlet end. A resonant chamber is proximate an airflow entrance end of the enclosure. The resonant chamber has first and second sections encompassing corresponding first and second volumes of different sizes. The different sizes are selected to form an acoustic resonator. The acoustic resonator attenuates noise from the blower over a selected attenuation frequency range.

Abstract: An online system matches source and target entities using multiple queues. The online system performs clustering of target entities to generate a plurality of clusters based on vector distances between pairs of target entities. Each cluster comprises target entities that are close to other target entities within the cluster compared to target entities of remaining clusters. The online system optimizes an aggregate score across the plurality of entities using a plurality of queues. Each queue is associated with a source entity and includes one or more target entities. The online system identifies a cluster of target entities based on a distance between the source entities and entities of the cluster of target entities. The online system selects a subset of target entities from the identified cluster using a machine learning based model trained to determine a score between an input source entity and target entity.

Abstract: A transport container is provided. The transport container includes a body having a base, a cover, an opening, and at least one side wall all defining a cavity therebetween. The transport container also includes an electronic controller. The electronic controller is configured to determine a geographic route from a carrier destination location to a destination location based on received carrier transfer information and received transportation information. The electronic controller is also configured to display the carrier transfer information on a user interface when the transport container is located at a carrier initial location. The electronic controller is further configured to deploy the transport container when the transport container is located at the carrier initial location.

Abstract: A loading apparatus of the present disclosure may be configured to receive one or more cartridges and assist with loading the one or more cartridges when received by the loading apparatus into a revolver. The loading apparatus may comprise a housing, a follower, a spring, and a release mechanism. The housing may include at least an upper end and a forward upper opening configured to receive therein and dispense therefrom the one or more cartridges. The spring is configured to apply an upward force to the follower towards the upper portion of the housing. The release mechanism may be defined on the housing and be configured to selectively disengage the upward force of the spring from an uppermost cartridge of the one or more cartridges while maintaining the upward force on the follower and any other cartridges of the one or more cartridges when received by the housing.

Abstract: Hydrogen purification devices and their components are disclosed. In some embodiments, the devices may include feed frame(s) and/or permeate frame(s) each having at least one elongate hole distinct and spaced from an open region, at least one output aperture, and/or at least one input aperture. The elongate hole may be disposed between the open region and the at least one input aperture. The elongate hole may be capable of receiving a portion of the mixed gas stream that leaks from the open region and/or at least one input conduit. The devices may additionally include gasket frames having at least one notch in one or more edges of a perimeter base. The notch may be in fluid communication with a longitudinal end portion of the elongate hole. The devices may further include first and second side plates that collectively enclose a plurality of frames.

Abstract: Compounds that selectively inhibit GluN2B-containing N-methyl-D-aspartic acid receptors (NMDARs) are disclosed. In some cases, the compounds selectively target GluN2B over GluN2A, GluN2C, and/or GluN2D. Generally, the compounds possess an enhanced potency to GluN2B at a pH that is more acidic compared to the physiological pH. Pharmaceutical formulations containing one or more of the compounds are also disclosed. Additionally, methods of treating a condition, disorder or disease using the compounds or their pharmaceutical formulations thereof are disclosed.

Abstract: A prosthetic knee can include a variable-torque magnetorheological (MR) actuator assembly or braking system, a frame and an electronics assembly or system that also serves as a mount for the knee actuator and facilitates in monitoring and controlling the operation of the knee actuator. The prosthetic knee system advantageously provides resistive forces to substantially simulate the position and motion of a natural knee joint during ambulation and/or other locomotory activities performed by the amputee. The prosthetic knee can be have a series of internal blades for providing resistive forces. A locking ratchet can be used to lock knee position. A dynamic seal with a protective shim can be disposed in the knee actuator. A coil with a non-circular cross-section can be used.

Abstract: Various implementations disclosed herein include devices, systems, and methods that interpret user activity as user interactions with user interface (UI) elements positioned within a three-dimensional (3D) space such as an extended reality (XR) environment. Some implementations enable user interactions with virtual elements displayed in 3D environments that utilize alternative input modalities, e.g., XR environments that interpret user activity as either direct interactions or indirect interactions with virtual elements.

Abstract: The present disclosure provides methods for treating cancer comprising administering one or more therapeutic agents for manipulation of a target gene (e.g., protein kinase, membrane associated tyrosine/threonine 1 (PKMYT1)), wherein the cancer has a mutation in, an altered (e.g., increased or decreased) expression level and/or an altered activity of a biomarker. Provided herein are methods for identifying biomarkers of the disclosure that form a synthetic lethal pair with a target gene (e.g., PKMYT1).

Abstract: A system and method for sub-merchant identification number (SMID) ingestion is disclosed. The method receives, from merchant aggregator, a transaction authorization request for a credit account customer and automatically scrapes the transaction authorization request for data to identify a sub-merchant. The method automatically determines a reward value of the sub-merchant for the credit account customer and automatically credits the customer with the determined reward.

Abstract: An apparatus, which is for connecting a first tubular and a second tubular in a downhole environment, includes a first component having a first component uphole end and a first component downhole end. The first component uphole end includes an uphole connection configured to connect to the first tubular. The apparatus includes a second component having a second component uphole end and a second component downhole end. The second component uphole end includes an extending portion and the second component downhole end includes a downhole connection configured to connect to the second tubular. The apparatus includes a weak point connection releasably connecting the first component downhole end to the second component uphole end. The weak point connection is releasable by applying uphole force on the first tubular, and the extending portion of the second component is exposed uphole by release of the weak point connection.

Abstract: An enterprise system may include one or more devices with sensors that measure operational parameters of the devices. The enterprise system may also include a sustainability platform system that obtains a sustainability model representative of a state of operations of the enterprise based on the measured operational parameters and receives sustainability target data that includes one or more threshold limits, one or more ranges, or both for one or more sustainability parameters. The sustainability platform system may also obtain one or more action plans for adjusting respective operations of the devices based on the sustainability model and the sustainability target data, simulate a performance of the action plans over a period of time relative to the sustainability parameters, and determine whether the simulated performance of the action plans is effective.

Abstract: Provided herein are antibodies that bind signal regulatory protein SIRP? and methods of making and using such antibodies. In some embodiments, the antibodies comprise an Fc, and are useful for preferential depletion of certain SIRP? expressing cells. In some embodiments, the antibodies provided herein are useful for treating a disease or condition associated with the dysregulation of cells (e.g. overactivation or aberrant proliferation of T-cells).

Abstract: An embodiment of an electronic processing system may include an application processor, persistent storage media communicatively coupled to the application processor, a graphics subsystem communicatively coupled to the application processor, an object space adjuster communicatively coupled to the graphics subsystem to adjust an object space parameter based on a screen space parameter, and a sample adjuster communicatively coupled to the graphics subsystem to adjust a sample parameter of the graphics subsystem based on a detected condition. Other embodiments are disclosed and claimed.

Abstract: Disclosed are methods and devices for detecting the presence or absence of cerebrospinal fluid (CSF) in a biological sample which normally does not contain CSF, in particular to the detection of the presence or absence of a tau protein in the biological sample. Also disclosed are devices and assays for the detection of the presence or absence of a tau protein indicating the presence or absence of CSF in a sample.

Abstract: The invention provides a method for producing embedded diffractive contact lenses involving use of a mold set in two-curing steps. The mold set consists of three mold halves, one of which is used twice, the first time for molding a diffractive insert and the second time for an embedded contact lens with the molded diffractive insert embedded therein. The twice-used mold half has been treated with a corona plasma or a vacuum UV in a central circular area having a diameter equal to or smaller than the diameter of the insert to ensure that the molded insert consistently adheres to the twice-used mold half, even though the other mating insert mold half for molding the diffractive insert has a great tendency to bind strongly the molded insert due to the diffractive structure on its molding surface.

Abstract: Certain aspects of the present disclosure provide techniques for parallel interaction with machine learning models. A method includes receiving first data in a first machine learning (ML) model interface window of a parallel interaction user interface, the first window is associated with a first identifier; receiving, within a prompt entry field in a second ML model interface window of the parallel interaction user interface, second data, wherein the second data includes the first identifier; responsive to a presence of the first identifier, generating a first ML model prompt based on the first data and the second data; providing the first ML model prompt to an ML model; receiving, from the ML model, a first model response; and displaying the first model response in the second ML model interface window.

Abstract: According to the present disclosure, air cleaner assemblies, components, features, and methods relating thereto, are described. These features, in part, relate to configuration of a preferred seal arrangement and seal surface of the cartridge. Particular arrangements are shown, in which: the filter cartridge includes a seal arrangement having a axial pinch seal surface with a projection/recess contour including at least one projection thereon; and, the cartridge includes a seal contour projection stabilizing portion at a location in perimeter alignment with the portion of the seal pinch arrangement including the first housing engagement projection. Additional features are included that relate to clean air separator section tubes of a precleaner arrangement secured to a cartridge. These features can be used in cartridges including features outlined above, or in alternative cartridges. Additional features of air cleaner arrangements and filter cartridges in accord with the above are described.