Abstract: A vehicle construction in which a survivability capsule and underbody V-deflector plate are located off-center relative to the vehicle providing desirable survivability and size characteristics, and minimizing overall vehicle width providing desirable maneuverability characteristics. The survivability capsule is constructed around occupants oriented to minimize capsule width and may incorporate traditional or spaced frame construction. The location of the capsule provides the ability to incorporate a large amount of storage area into the construction of the vehicle, or to use a spaced armor array on one side of the capsule providing protection from road-side threats including EFPs, RPGs, and RKG-3s.

Abstract: A method and apparatus for registering physical space to image space is disclosed. The system allows for determining fiducial markers as pixels or voxels in image data. The system can correlate and register the determined fiducial points with fiducial markers in physical space.

Abstract: A method for tone mapping a high dynamic range image of a large terrestrial area into a lower dynamic range image uses: globally aware, locally adaptive approach whereby local tonal balancing parameter values are derived from known tone mapping parameters for a local 3×3 matrix of image tiles and used in turn to derive a local sigmoid transfer function for pixels in the tile in the middle of the matrix. A global sigmoid transfer function is derived based on values of the tone mapping parameters applicable to the entire image. A lower dynamic range image pixel will have a local tone mapped value and a globally tone mapped value, which are combined by giving each a weighted value to provide a final low dynamitic range pixel value.

Abstract: Techniques for atmospheric and solar correction of aerial images are described. An apparatus may comprise an atmospheric and solar component arranged for execution by a logic device and operative to correct solar and atmosphere artifacts from an aerial image. The atmospheric and solar component may comprise an image information component operative to generate an image record for each aerial image of a group of aerial images, the image record comprising statistical information and image context information for each aerial image, a filter generation component operative to generate an atmospheric filter and a solar filter from the statistical information and the image context information stored in the image records, and an image correction component operative to correct atmospheric and solar artifacts from the aerial image using the respective atmospheric filter and solar filter. Other embodiments are described and claimed.

Abstract: The present invention relates to compounds of the formula and pharmaceutically acceptable salts, solvates or tautomers thereof, to processes for the preparation of, intermediates used in the preparation of, and compositions containing such compounds, and the uses of such compounds, in particular for the treatment of pain.

Abstract: A UV-IR combination curing system and method for manufacture and repair of composite parts, such as for use in wind blade manufacture and repair. The system and method utilize UV and IR dual radiation sources to cure glass fiber reinforced laminates containing a photo initiator. The UV and IR dual radiation sources can be configured as discrete stand-alone UV and IR lamps used in a side by side configuration, a plurality of UV lamps with thermal IR radiation, a combined UV/IR lamp, or other forms of light sources providing both UV and IR radiation. To achieve high glass transition and complete curing of thick laminates, the IR radiation source is initially turned on to heat the laminate to close to 40° C-100° C. before the UV radiation source is turned on. The IR radiation source can be turned off after UV radiation source is activated.

Abstract: Disclosed herein is an LED-based light for replacing a fluorescent bulb in a conventional fluorescent light fixture. The LED-based light includes a housing having a first end opposing a second end, a circuit board disposed within the housing and extending along a longitudinal axis of the housing, at least one LED mounted to the circuit board, at least one end cap disposed on one of the first and second ends of the housing, the end cap including a switch and at least one electrically conductive pin configured for physical and electrical connection to the light fixture; and circuitry configured to provide a current path between the at least one LED and the at least one electrically conductive pin, wherein the switch is configured to selectively disconnect the current path.

Abstract: The present invention relates to compounds of the formula and pharmaceutically acceptable salts, solvates or tautomers thereof, to processes for the preparation of, intermediates used in the preparation of, and compositions containing such compounds, and the uses of such compounds, in particular for the treatment of pain.

Abstract: A method and apparatus for registering physical space to image space is disclosed. The system allows for determining fiducial markers as pixels or voxels in image data. The system can correlate and register the determined fiducial points with fiducial markers in physical space.

Abstract: An impedance tomography apparatus is disclosed for the measuring of the electrical activity of excitable tissue. The apparatus comprises a plurality of signal transfer devices adapted for transferring an input signal to a body and receiving an output signal from a body. An input signal generator is adapted to generate an electrical input signal and apply it to at least one of the signal transfer devices. A measurement device is arranged to measure the output signal from the body at least one or more of the remaining signal transfer devices, wherein the input signal generator is adapted to generate an input signal of frequency greater than 100 Hz and less that 5 kHz. This allows the depolarisation of nervous or muscle tissue to be imaged.

Abstract: The invention provides a functionalised compound of formula (II), which functionalised compound comprises n carbene precursor groups which are the same or different, wherein n is an integer equal to or greater than 3: wherein x is 1, E is a group which is capable of being converted into a carbene reactive intermediate group, Q is a core moiety, a polymer or a dendrimer, and each of the [R]x-E-L- groups, which are the same or different, is independently selected from a group of formula (Ie) and a group of formula (Ia): wherein L is a single bond or a linker group as defined herein, R is a terminal group as defined herein, and R1 is as defined herein. Further provided is the use of the functionalised compound as an agent for producing a chemically-bound three-dimensional network on or within a substrate.

Abstract: The invention relates to a method of assessing the proliferation or differentiation behavior of a population of target cells in a biological system, said method comprising the steps of; [a] measuring the value of at least one proliferation characteristic of said cells at least one time point t, wherein said proliferation characteristic is the clone size distribution; [b] comparing the clone size distribution measured in [a] to a reference clone size distribution at a corresponding time point t predicted or described by the equation; wherein a difference between the measured clone size distribution of [a] and the predicted or described clone size distribution of [b] indicates an altered proliferation or differentiation behavior of said cells. The invention further relates to methods involving assessing the scaling form of the above behaviors, values of the parameters, and inferring effects on cell proliferation and/or differentiation therefrom.

Abstract: The invention relates to sulfonamide derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to a new sulfonamide Nav1.7 inhibitors of formula (I): or a pharmaceutically acceptable salt thereof, wherein Ar1, X, R1, R2, R3, R4 and R5 are as defined in the description. Nav 1.7 inhibitors are potentially useful in the treatment of a wide range of disorders, particularly pain.

Abstract: The invention relates to sulfonamide derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to a new sulfonamide Nav1.7 inhibitors of formula (I): or a pharmaceutically acceptable salt thereof, wherein Het1, X, R1, R2, R3, R4 and R5 are as defined in the description. Nav 1.7 inhibitors are potentially useful in the treatment of a wide range of disorders, particularly pain.

Abstract: An LED light tube and method of manufacturing an LED light tube includes the steps of forming an LED light tube housing of a first housing segment joined to a first end cap. One end of a circuit board is inserted through the one housing segment into contact with the first end cap. One or more additional housing segments are slid over the circuit board into engagement with ends of previously mounted housing segments. A second end cap is joined to the engaged ends of the multiple housing segments are fixed together to complete a unitary housing.

Abstract: A mobile retail store structure transportable to a plurality of different locations includes a trailer construction configured both exteriorly and interiorly for housing a plurality of storage bins wherein products and/or parts can be stored. Each trailer is a self-sufficient module which includes doors at one end of the trailer unit for entry and exit thereto, portable stairs for providing access to the entry doors, opposed side doors and associated walkways for allowing coupling to additional similarly constructed trailers, extendable canopies for providing a secure passageway between the respective coupled trailers, and a generator/HVAC system for providing heating, cooling and electrical power to each trailer unit. In one embodiment, a terminal is provided to allow a user to either browse electronically various items for selection and/or sale, or access a self-service check-out station to complete a transaction.

Abstract: A compound of formula (I), or a pharmaceutical acceptable salt and/or solvate (including hydrate) thereof; and the use of a compound of formula (I) in the treatment of a TNF-mediated disease, disorder, or condition, or a p38-mediated disease, disorder, or condition, in particular the allergic and non-allergic airways diseases, more particularly obstructive or inflammatory airways diseases, preferably chronic obstructive pulmonary disease.

Abstract: The invention relates to a method of assessing the proliferation or differentiation behaviour of a population of target cells in a biological system, said method comprising the steps of; [a] measuring the value of at least one proliferation characteristic of said cells at least one time point t, wherein said proliferation characteristic is the clone size distribution; [b] comparing the clone size distribution measured in [a] to a reference clone size distribution at a corresponding time point t predicted or described by the predicted or described clone size distribution of [b] indicates an altered proliferation or differentiation behaviour of said cells. The invention further relates to methods involving assessing the scaling form of the above behaviours, values of the parameters, and inferring effects on cell proliferation and/or differentiation therefrom.

Abstract: There is provided a device comprising a body structure having one or more surfaces wherein at least one of the surfaces comprises a pH sensitive layer comprising a linear polymer, wherein the water solubility of the linear polymer increases from a first water solubility to a second water solubility at a pH trigger. A method of forming a device, and a method of preventing or mitigating infection is also described.

Abstract: A mobile device (301) for use in a wireless communication network, said mobile device comprising a processor (335) arranged to send a short message delivery receipt to a communication party, after normal receipt by the communication device of a first short message sent by said communication party, said first short message delivery receipt being in a byte format different than the received first short message, Send mobile originated (MO) short messages, of the same byte format as the received first short message, transfer the received first short message to an identification module (350) of the mobile device when said first short message is identified as a data update message comprising a data update for said identification module, the processor being further arranged, upon determination by the authentication module that the communication party requested from said authentication module that proof of receipt (PoR) data for the data update be inserted in a new MO short message serving as a PoR message to said co