Abstract: The systems and methods disclosed herein receive alphanumeric characters defining operative boundaries for expected model use cases, along with operational data. The expected model use cases share common attributes, which are used by a first AI model to construct observed model use cases from the operational data. Each observed model use case includes features such as a text-based description, expected input and output, AI model(s) generating the expected output from the input, and/or data supporting the AI models. For each observed model use case, a second AI model maps the alphanumeric characters and features to a risk category, selecting from multiple risk categories based on the level of risk associated with the features. The system identifies criteria for the observed model use case within the alphanumeric characters and generates gaps by comparing the criteria with the features of the observed model use case.

Abstract: The systems and methods disclosed herein receives, from a computing device, operational data indicating software or hardware assets used on informational assets, and obtains set of alphanumeric characters defining operative boundaries for expected system assets, which include a set of common attributes. Using the set of attributes, a first set of AI models determines observed system assets from the operational data, each with specific features. A second set of AI models associates each information asset with the corresponding observed system assets. For each observed system asset, a third set of AI models identifies criteria within the alphanumeric characters, compares the criteria with the asset's features to identify gaps, and generates actions to ensure the observed system asset meets the identified criteria.

Abstract: Systems, methods, and devices that relate to intelligent query decomposition and parallel routing for specialized model processing are disclosed. In one example aspect, the system receives a query from a user comprising a request relating to a particular domain. The system determines, using a decomposition model, a set of sub-queries based on semantic boundaries, syntactics, tasks, relationships, and rules relating to particular domains. The system inputs the set of sub-queries into a routing model to determine a set of specialized models. For each sub-query, the system routes the sub-query to a respective specialized model, generates an output, and assigns a confidence score. The system detects conflicts among outputs using a conflict detection model configured to identify discrepancies. The system generates an aggregated output by combining outputs according to a weighted aggregation algorithm prioritizing higher confidence scores and conflict resolution rules, then displays the aggregated output.

Abstract: Systems for explainable large language model routing with immutable audit trails are disclosed. The system receives a query and determines its characteristics including complexity, domain, regulatory constraints, and performance requirements. It retrieves profiles for multiple LLMs from a model matrix containing performance attributes, resource consumption, and compliance parameters. The system selects a particular LLM by balancing resource consumption with performance requirements, evaluating regulatory compliance, ranking LLMs based on these factors, and prioritizing models with successful processing history. The system generates a human-readable explanation of the selection including decision factors, rationale, and alternatives considered. Finally, it records the selection and explanation in a tamper-evident, immutable audit trail data structure.

Abstract: Provided herein are, inter alia, extracellular products (e.g., vesicles such as microvesicles, e.g., exosomes) produced by renal cells (such as bioactive renal cells, e.g., selected renal cells). Methods of altering components (such as miRNAs or proteins) of vesicles produced by cells, as well as methods of producing vesicles comprising various compounds are also included. Also provided are diagnostic and treatment methods.

Abstract: Systems and methods disclosed herein automatically authorize, audit, and manage usage of protected digital content via agentic artificial intelligence (AI) models. A data access/usage request is received (e.g., from a graphical user interface) that is associated with digital assets licensed from third parties. The system uses a first AI agent set to identify the digital content and retrieve corresponding access policies from a distributed database. The system uses a second AI agent set (same as or different from the first AI agent set) to evaluate the request against the retrieved policy to generate a permission set and/or settlement instructions. The system uses a third AI agent set (same as or different from the first and/or second AI agent sets) to embed digital watermarks and/or cryptographic signatures into the accessed content, and to record an audit trail of access, authorization, and/or settlement events in a distributed ledger or database.

Abstract: The systems and methods disclosed herein obtain a set of alphanumeric characters defining constraints for agents and the agents' operational data. Each agent uses an output from a first set of artificial intelligence (AI) models and predefined objectives to autonomously generate proposed actions for execution on software application(s). For each agent, a second set of AI models evaluates the agent by identifying gaps in the proposed actions by comparing them with the expected actions. Using a third set of AI models and the identified gaps, the systems modify the proposed actions by adding, altering, or removing actions from the proposed actions.

Abstract: Systems and methods disclosed herein automatically register, monitor, and authenticate distributed artificial intelligence (AI) agents and their operational contexts using a distributed or federated ledger-based agent knowledge registry. The system obtains a registration or query request (e.g., from an AI agent, orchestrator, or user interface) to identify or store operational context linked to each AI-based agent. The system determines a feature set of agent metadata and operational parameters using a first AI model set, and dynamically generates a cryptographically verifiable registry record set using a second AI model set (same as or different from the first AI model set) based on the operational feature set, to be stored in a distributed ledger database.

Abstract: Systems and methods disclosed herein automatically evaluate, select, and coordinate artificial intelligence (AI)-based agents for collaborative distributed task execution based on dynamic, multi-attribute scoring and resource allocation models. The system obtains a task specification request defining a computational requirement set, a performance metric set, and an available resource set for one or more tasks to be executed by a network of AI-based agents. A first AI model set generates domain-specific test datasets and validates prospective agents by comparing agent-generated fingerprints against predetermined hash values stored on a distributed or federated ledger. A second AI model set constructs a multi-dimensional scoring data structure for each agent by using historical performance metrics to compute weighted composite scores. The system selects a subset of AI-based agents, ranks the agents, and allocates resources proportional to each agent's composite score.

Abstract: Systems and methods disclosed herein automatically detect, analyze, and mitigate anomalous resource distribution among artificial intelligence (AI)-based agents within a distributed computational network. The system receives a resource allocation request specifying computational resources, agent parameters, and performance objectives for a network of agents. A first AI model set monitors agent activity by tracking resource consumption and behavioral deviations from baseline profiles. The system compares resource usage of agents with historical norms and/or predetermined thresholds to generate an anomaly score for each agent. A second AI model set aggregates scores to construct a multi-dimensional data structure that indicates the comparison and anomaly score. The system ranks agents by anomaly severity to isolate agents with high scores (e.g., misaligned agents), and reallocates resources and updates access privileges for the misaligned agents.

Abstract: The systems and methods disclosed herein receives, from a computing device, operational data indicating software or hardware assets used on informational assets, and obtains a set of alphanumeric characters defining operative boundaries for expected system assets, which include a set of common attributes. Using the set of attributes, a first set of AI models determines observed system assets from the operational data, each with specific features. A second set of AI models associates each information asset with the corresponding observed system assets. For each observed system asset, a third set of AI models identifies criteria within the alphanumeric characters, compares the criteria with the asset's features to identify gaps, and generates actions to ensure the observed system asset meets the identified criteria.

Abstract: The systems and methods disclosed herein receive an output generation request from that includes input for generating an output using a language model. The input includes a set of alphanumeric characters associated with operative standards for a first set of actions. The system divides the set of alphanumeric characters into text subsets. For each text subset, a vector representation is determined. Prompts are created for each vector representation including the set of alphanumeric characters, query contexts, keywords, and/or the text subset. Each vector representation's prompt is input into the language model, which generates a second set of actions of related actions, where subsequently generated actions are based on prior generated actions. The system aggregates the second set of actions into a third set of actions and displays a graphical layout. The graphical layout displays a representation of the set of alphanumeric characters and the corresponding actions.

Abstract: The systems and methods disclosed herein receive alphanumeric characters defining operative boundaries for expected model use cases, along with operational data. The expected model use cases share common attributes, which are used by a first AI model to construct observed model use cases from the operational data. Each observed model use case includes features such as a text-based description, expected input and output,? AI model(s) generating the expected output from the input, and/or data supporting the AI models. For each observed model use case, a second AI model maps the alphanumeric characters and features to a risk category, selecting from multiple risk categories based on the level of risk associated with the features. The system identifies criteria for the observed model use case within the alphanumeric characters and generates gaps by comparing the criteria with the features of the observed model use case.

Abstract: Systems for explainable large language model routing with immutable audit trails are disclosed. The system receives a query and determines its characteristics including complexity, domain, regulatory constraints, and performance requirements. It retrieves profiles for multiple LLMs from a model matrix containing performance attributes, resource consumption, and compliance parameters. The system selects a particular LLM by balancing resource consumption with performance requirements, evaluating regulatory compliance, ranking LLMs based on these factors, and prioritizing models with successful processing history. The system generates a human-readable explanation of the selection including decision factors, rationale, and alternatives considered. Finally, it records the selection and explanation in a tamper-evident, immutable audit trail data structure.

Abstract: Systems, methods, and devices that relate to intelligent query decomposition and parallel routing for specialized model processing are disclosed. In one example aspect, the system receives a query from a user comprising a request relating to a particular domain. The system determines, using a decomposition model, a set of sub-queries based on semantic boundaries, syntactics, tasks, relationships, and rules relating to particular domains. The system inputs the set of sub-queries into a routing model to determine a set of specialized models. For each sub-query, the system routes the sub-query to a respective specialized model, generates an output, and assigns a confidence score. The system detects conflicts among outputs using a conflict detection model configured to identify discrepancies. The system generates an aggregated output by combining outputs according to a weighted aggregation algorithm prioritizing higher confidence scores and conflict resolution rules, then displays the aggregated output.

Abstract: Methods of identifying an enriched heterogeneous renal cell population having therapeutic potential, enriched heterogeneous renal cell populations having therapeutic potential and uses for same.

Abstract: The systems and methods disclosed herein relate to querying data using artificial intelligence models. A generalized model receives an output generation request and partitions it into segments mapped to specific domains, where each domain indicates associated databases and guidelines. The segments are routed to domain-specific models trained on domain-specific data, which generate query fragments by comparing performance metrics and system resource usage metrics. The query fragments are aggregated into an overall query that satisfies guidelines across domains. The systems and methods can include a feedback loop to adjust the domain-specific models using user interactions and performance metrics to dynamically adapt to a skill level or experience of the user.

Abstract: A strongly consistent distributed data storage system comprises an enhanced metadata service that is capable of fully recovering all metadata that goes missing when a metadata-carrying disk, disks, and/or partition fail. An illustrative recovery service runs automatically or on demand to bring the metadata node back into full service. Advantages of the recovery service include guaranteed full recovery of all missing metadata, including metadata still residing in commit logs, without impacting strong consistency guarantees of the metadata. The recovery service is network-traffic efficient. In preferred embodiments, the recovery service avoids metadata service downtime at the metadata node, thereby reducing the impact of metadata disk failure on the availability of the system. The disclosed metadata recovery techniques are said to be “self-healing” as they do not need manual intervention and instead automatically detect failures and automatically recover from the failures in a non-disruptive manner.

Abstract: Provided herein are, inter alia, extracellular products (e.g., vesicles such as microvesicles, e.g., exosomes) produced by renal cells (such as bioactive renal cells, e.g., selected renal cells). Methods of altering components (such as miRNAs or proteins) of vesicles produced by cells, as well as methods of producing vesicles comprising various compounds are also included. Also provided are diagnostic and treatment methods.

Abstract: The systems and methods disclosed herein obtain a set of alphanumeric characters defining constraints for agents and the agents' operational data. Each agent uses an output from a first set of artificial intelligence (AI) models and predefined objectives to autonomously generate proposed actions for execution on software application(s). For each agent, a second set of AI models evaluates the agent by identifying gaps in the proposed actions by comparing them with the expected actions. Using a third set of AI models and the identified gaps, the systems modify the proposed actions by adding, altering, or removing actions from the proposed actions.