Abstract: A tissue traction system with a tissue traction device operably separably coupled with a delivery device. The tissue traction device may be engaged with tissue and separated from the delivery device by breaking a frangible connection between the tissue traction device and the delivery device. The tissue traction device may be implanted into tissue and may have a shape memory configuration which is constrained by the tissue upon implanting of the tissue traction device with respect to the tissue, and which is allowed to relax into an unconstrained curved configuration as the target tissue is cut from surrounding to tissue to apply traction to the cut target tissue.

Abstract: Medical devices and accessories for accessing the biliary tract include a tubular member with a tapered distal region adapted for endoscope insertion. The distal region can expand to accommodate endoscope advancement and contract upon retraction, utilizing accordion folds or axial slots that splay outward. An accessory device includes a mounting member with tapered prongs that spread apart as an endoscope advances. The devices may include proximal handles with steering and locking mechanisms.

Abstract: A tissue traction system and associated devices and method for applying traction to target tissue within a patient’s body by applying a force to an elongate element operably associated with the target tissue. The system may include two or more tissue-engagement elements operably associated with the elongate element. One of the tissue-engagement elements may be engaged with the target tissue, and another tissue-engagement element may be engaged with tissue at a vector-changing location spaced apart from the target tissue. The elongate element is fixedly coupled to the anchor tissue-engagement element to apply traction to the target tissue via the anchor tissue-engagement element, and is movably operably associated with a traction-adjusting tissue-engagement element to modify the traction force vector applied to the target tissue. The system may be delivered external to a working channel of a medical delivery device such as a medical scope.

Abstract: A medical device, comprising a handle, wherein the handle includes a movable body and a stationary body; an end cap, the end cap comprising an inner cap and an outer cap, wherein the inner cap is coupled to the movable body by a control element such that movement of the movable body relative to the stationary body extends the inner cap relative to the outer cap; and a patch disposed between the inner cap and the outer cap such that movement of the inner cap relative to the outer cap at least partially deploys the patch.

Abstract: A medical device may include a handle including a fixed body and a movable body. The movable body may be movable relative to the fixed body. The medical device may include a shaft extending from the fixed body and an end effector at a distal end of the shaft. Rotation of the movable body relative to the fixed body may permit rotation of the end effector relative to the shaft, and rotation of the movable body with rotation of the fixed body may permit rotation of the end effector with the shaft. Deflection of the movable body relative to the fixed body may permit deflection of the end effector relative to the fixed body.

Abstract: A system includes an adapter mounted over a distal end of an insertion device, a clip and a first extending member. The clip includes jaws movable between an insertion configuration, with the jaws separated and an initial deployed configuration with the jaws drawn together. The clip is biased toward the initial configuration. The first jaw includes a connection element and a first member releasably coupled to the first jaw connection element permits movement of the adapter relative to the clip while the first member remains coupled to the clip to enhance visual observation of the clip. The first member retracts the clip proximally over the adapter so that the clip is forced open as the clip is retracted over the adapter freeing the clip from tissue on which it had been clipped.

Abstract: A system includes a cap having first and second cap members, a clip, and first and second coupling members. The clip includes a first part rotatably coupled to a second part and first members coupled to the first part and corresponding second members coupled to the second part. Each of the first members is coupled to a corresponding one of the second members to form an iris mechanism operating to alter a size of a central opening of the clip when the parts are rotated relative to one another between open/closed configurations. The first coupling member is coupled between the first cap member and the first part, and the second coupling member is coupled between the second cap member and the second part so that, upon rotation of the first cap member relative to the second cap member, the first part is rotated relative to the second part.

Abstract: A method for fabricating an optic element The method may include: fabricating a first mold having a pattern of the optic element; fabricating a second mold with a soft material by using the first mold, the second mold having an opposite pattern to the pattern of the optic element; forming a nanocomposite layer on a substrate, where the nanocomposite layer comprises nanoparticles embedded therein, the nanocomposite layer having a refractive index which is equal to or greater than 2; placing the second mold onto the nanocomposite layer and curing the nanocomposite layer; and demolding the cured nanocomposite layer from the second mold to obtain the optic element.

Abstract: A medical device includes a handle including a main body and a movable body, a sheath element coupled to the handle, an actuation element disposed within the sheath element, an end cap configured to be coupled to a distal end of another medical device, and a patch positioned on the end cap and coupled to the actuation element. The patch includes a mesh and an expandable structure coupled to the mesh. The expandable structure is configured to be coupled to the actuation element, and the expandable structure is further configured to cause the mesh to retract and expand.

Abstract: A medical device for removing stones from a body lumen includes an elongate shaft with inner and outer loops that extend from the shaft. The inner and outer loops are movable between a capture configuration, where the inner loop plane is substantially orthogonal to the outer loop plane, and a release configuration, where the loops are substantially parallel. The elongate shaft includes an outer tubular member, an inner tube within the outer tubular member, and a core wire within the inner tube. The inner loop connects to the core wire while the outer loop connects to the inner tube. A handle secured to the elongate shaft includes a rotatable knob coupled to the core wire and a sliding element that enables translation of the core wire to control loop movement and configuration.

Abstract: A clipping system for treating tissue includes an adapter, a clip, an extending member, and a control wire. The adapter is mounted over an insertion device. The clip is mounted over the adapter and includes a connecting member connecting to first and second jaws. The jaws are configured to move between an insertion configuration and an initial deployed configuration. The extending member is coupled to the clip and the adapter and extends to abut the connecting member. The control wire is received within the extending member to move the clip between the insertion configuration, the initial deployed configuration and a review configuration. The control wire connects to the clip via a releasable link to retract the clip proximally over the adapter to force the clip to open. The releasable link is configured to release when the control wire is subject to a force exceeding a predetermined threshold value.

Abstract: A traction device and system configured for use with a medical delivery device having a lumen through which medical instruments are delivered. The traction device and system allow for delivery and/or deployment of the traction device independently of delivery of medical instruments through the medical delivery device. Additionally or alternatively, the traction device and system allow for manipulation and/or control of the traction device independently of manipulation and control of other medical instruments. Additionally or alternatively, the traction device and system allow for application of multi-vector traction to a target tissue. The traction device may be controlled from outside the patient’s body to apply traction to target tissue within a patient’s body.

Abstract: An assembly of a medical delivery device includes an inner sleeve including a flange at a proximal end. The flange includes one or more through holes. The assembly also includes an outer sleeve movably coupled to the inner sleeve. A distal tip of the outer sleeve includes a plurality of openings for delivering an adhesive to a treatment site. The assembly further includes a cavity formed between the inner sleeve and the outer sleeve and configured to hold the adhesive prior to the delivering. The assembly yet further includes one or more actuators connected to a proximal end of the outer sleeve and extended via the one or more through holes to a handle of the medical delivery device. Actuation of the one or more actuators moves one of the inner sleeve or the outer sleeve relative to the other to cause the delivering of the adhesive.

Abstract: A steerable medical device may include a proximal elongate shaft having a first plurality of lumens and a distal elongate shaft having a second plurality of lumens, wherein the second plurality is less than the first plurality. An articulation assembly may couple the proximal and distal elongate shafts. The articulation assembly may include a segmented sleeve coupled to the proximal elongate shaft and an articulating connector pivotably coupled to the segmented sleeve and coupled to the distal elongate shaft. At least one deflection member may extend through a dedicated lumen of the proximal elongate shaft and may be couple to the articulating connector. Selective actuation of the deflection member may cause lateral deflection of the distal elongate shaft relative to the proximal elongate shaft.

Abstract: A tissue-engagement member having a pair of jaws movable between a closed configuration and an open configuration, an actuator movable to shift the jaws between the closed and open configurations, and a biasing element biasing the jaws into a closed configuration. The biasing element may be provided over a portion of the tissue-engagement member. A cam mechanism may be provided in operative association with at least one of the jaws and/or the actuator. The biasing element may operatively engage at least one of the jaws and/or the actuator to actuate the cam mechanism to return the jaws to a closed configuration from an open configuration. A manipulator having an actuator-engagement element may be provided to engage an actuation element operatively associated with the actuator. The actuator-engagement element may operatively engage the actuation element in a range of orientations.

Abstract: A clipping system includes an adapter, a clip and a first extending member. The clip includes first and second jaws which are movable between an insertion configuration and an initial deployed configuration. The jaws are biased toward the initial configuration. The first member is releasably coupled to the clip and movably connected to the adapter. The first member includes a distal end releasably coupled to the first jaw such that longitudinal movement of the first member relative to the adapter moves the clip between the insertion configuration, the initial configuration and a review configuration. The first member is operable to retract the clip proximally over the adapter so that the clip is forced open as the clip is retracted over the adapter. A first releasable link connects the first member to the clip and releases when the first member is subject to a force exceeding a predetermined threshold value.

Abstract: A medical device includes a handle, an actuator rotatably coupled to the handle, a shaft extending distally from the handle, and a sheath including a plurality of branches. The plurality of branches are secured to the actuator at a proximal end and to the shaft at a distal end. The actuator is configured to articulate the shaft by rotating relative to the handle and translating at least one of the plurality of branches relative to the remaining plurality of branches.

Abstract: A clipping system includes an adapter and a clip. The proximal portion of the adapter extends along a first longitudinal axis. The distal portion of the adapter includes a cylinder extending along a second longitudinal axis that extends substantially perpendicular relative to the first axis. The clip includes first and second pairs of arms and first and second jaws. Proximal ends of the first arms are connected via a first hinge. Proximal ends of the second arms are connected via a second hinge. The first jaw extends between distal ends of a first one of the first arms and a first one of the second arms. The second jaw extends between distal ends of a second one of the first arms and a second one of the second arms so that the jaws are movable relative to one another between open and closed configurations.

Abstract: A medical device may comprise a handle, wherein the handle includes a movable body and a main body; a cap configured to be coupled to a distal end of a scope; a patch, wherein the patch is moveable relative to the cap; and a petal body. The patch may be removably coupled to the petal body. The medical device may further comprise an actuator body coupling the patch to the moveable body such that movement of the moveable body extends the patch from the cap. The petal body may be configured to transition between a closed configuration in which the patch is retracted, and an open configuration in which the patch is extended radially-outward from a central longitudinal axis of the scope.

Abstract: A system includes a clip, a first control member, and an adapter including a channel extending from a proximal end to a distal end. The clip includes a base portion mounted over a periphery of the adapter and arms extending distally from the portion. The arms are movable relative to one another between insertion and initial deployed configurations. The first member is releasably coupled to the portion and is movably connected to the adapter so that a longitudinal movement of the first member relative to the adapter moves the clip between the insertion configuration, the initial deployed configuration, and a review configuration. The first member is operable to retract the clip proximally over the adapter toward the insertion configuration so that the arms is forced open as the clip is retracted over the adapter freeing the clip from tissue on which it had been clipped.