Abstract: An assembly of a medical delivery device includes an inner sleeve including a flange at a proximal end. The flange includes one or more through holes. The assembly also includes an outer sleeve movably coupled to the inner sleeve. A distal tip of the outer sleeve includes a plurality of openings for delivering an adhesive to a treatment site. The assembly further includes a cavity formed between the inner sleeve and the outer sleeve and configured to hold the adhesive prior to the delivering. The assembly yet further includes one or more actuators connected to a proximal end of the outer sleeve and extended via the one or more through holes to a handle of the medical delivery device. Actuation of the one or more actuators moves one of the inner sleeve or the outer sleeve relative to the other to cause the delivering of the adhesive.

Abstract: A steerable medical device may include a proximal elongate shaft having a first plurality of lumens and a distal elongate shaft having a second plurality of lumens, wherein the second plurality is less than the first plurality. An articulation assembly may couple the proximal and distal elongate shafts. The articulation assembly may include a segmented sleeve coupled to the proximal elongate shaft and an articulating connector pivotably coupled to the segmented sleeve and coupled to the distal elongate shaft. At least one deflection member may extend through a dedicated lumen of the proximal elongate shaft and may be couple to the articulating connector. Selective actuation of the deflection member may cause lateral deflection of the distal elongate shaft relative to the proximal elongate shaft.

Abstract: A tissue-engagement member having a pair of jaws movable between a closed configuration and an open configuration, an actuator movable to shift the jaws between the closed and open configurations, and a biasing element biasing the jaws into a closed configuration. The biasing element may be provided over a portion of the tissue-engagement member. A cam mechanism may be provided in operative association with at least one of the jaws and/or the actuator. The biasing element may operatively engage at least one of the jaws and/or the actuator to actuate the cam mechanism to return the jaws to a closed configuration from an open configuration. A manipulator having an actuator-engagement element may be provided to engage an actuation element operatively associated with the actuator. The actuator-engagement element may operatively engage the actuation element in a range of orientations.

Abstract: A clipping system includes an adapter, a clip and a first extending member. The clip includes first and second jaws which are movable between an insertion configuration and an initial deployed configuration. The jaws are biased toward the initial configuration. The first member is releasably coupled to the clip and movably connected to the adapter. The first member includes a distal end releasably coupled to the first jaw such that longitudinal movement of the first member relative to the adapter moves the clip between the insertion configuration, the initial configuration and a review configuration. The first member is operable to retract the clip proximally over the adapter so that the clip is forced open as the clip is retracted over the adapter. A first releasable link connects the first member to the clip and releases when the first member is subject to a force exceeding a predetermined threshold value.

Abstract: A medical device includes a handle, an actuator rotatably coupled to the handle, a shaft extending distally from the handle, and a sheath including a plurality of branches. The plurality of branches are secured to the actuator at a proximal end and to the shaft at a distal end. The actuator is configured to articulate the shaft by rotating relative to the handle and translating at least one of the plurality of branches relative to the remaining plurality of branches.

Abstract: A clipping system includes an adapter and a clip. The proximal portion of the adapter extends along a first longitudinal axis. The distal portion of the adapter includes a cylinder extending along a second longitudinal axis that extends substantially perpendicular relative to the first axis. The clip includes first and second pairs of arms and first and second jaws. Proximal ends of the first arms are connected via a first hinge. Proximal ends of the second arms are connected via a second hinge. The first jaw extends between distal ends of a first one of the first arms and a first one of the second arms. The second jaw extends between distal ends of a second one of the first arms and a second one of the second arms so that the jaws are movable relative to one another between open and closed configurations.

Abstract: A medical device may comprise a handle, wherein the handle includes a movable body and a main body; a cap configured to be coupled to a distal end of a scope; a patch, wherein the patch is moveable relative to the cap; and a petal body. The patch may be removably coupled to the petal body. The medical device may further comprise an actuator body coupling the patch to the moveable body such that movement of the moveable body extends the patch from the cap. The petal body may be configured to transition between a closed configuration in which the patch is retracted, and an open configuration in which the patch is extended radially-outward from a central longitudinal axis of the scope.

Abstract: A system includes a clip, a first control member, and an adapter including a channel extending from a proximal end to a distal end. The clip includes a base portion mounted over a periphery of the adapter and arms extending distally from the portion. The arms are movable relative to one another between insertion and initial deployed configurations. The first member is releasably coupled to the portion and is movably connected to the adapter so that a longitudinal movement of the first member relative to the adapter moves the clip between the insertion configuration, the initial deployed configuration, and a review configuration. The first member is operable to retract the clip proximally over the adapter toward the insertion configuration so that the arms is forced open as the clip is retracted over the adapter freeing the clip from tissue on which it had been clipped.

Abstract: A device includes a capture assembly, a hollow member, a tube, and a control member. The assembly includes a capture sleeve received on a distal end of an insertion device and a flange mounted on the insertion device proximal of the sleeve. The hollow member, the tube, and the control member each have a proximal end accessible by the user. The tube pushes the sleeve distally off the insertion device when the tube is advanced distally through the hollow member. The control member includes a distal end forming a loop coupled around a circumference of a distal opening of the sleeve. The loop moves between a constricted configuration in which at least a portion of the loop is drawn proximally into the tube and an open configuration in which the loop is extended distally from the tube to open the loop and the distal opening of the sleeve.

Abstract: A medical device may include a handle having an actuator. A medical device may include a shaft. A medical device may include an end effector at a distal end of the medical device, wherein the actuator is configured to (1) articulate the shaft in response to moving the actuator in a first direction relative to a body of the handle and (2) actuate the end effector in response to moving the actuator in a second direction relative to the body of the handle.

Abstract: A system includes a cap having first and second cap members, a clip, and first and second coupling members. The clip includes a first part rotatably coupled to a second part and first members coupled to the first part and corresponding second members coupled to the second part. Each of the first members is coupled to a corresponding one of the second members to form an iris mechanism operating to alter a size of a central opening of the clip when the parts are rotated relative to one another between open/closed configurations. The first coupling member is coupled between the first cap member and the first part, and the second coupling member is coupled between the second cap member and the second part so that, upon rotation of the first cap member relative to the second cap member, the first part is rotated relative to the second part.

Abstract: A medical device includes a handle with a primary actuator and one or more secondary actuators, an end cap configured to be coupled to a distal end of another medical device and including stationary and movable portions, one or more patches that are coupled to the movable portion, one or more control elements coupling the primary actuator to the movable portion; and one or more actuation elements. The one or more actuation elements extend from the one or more secondary actuators to a position between a portion of the one or more patches and the movable portion of the end cap. Movement of the primary actuator moves the movable portion of the end cap relative to the stationary portion of the end cap, and movement of the one or more secondary actuators at least partially deploys the one or more patches from the movable portion of the end cap.

Abstract: A system includes an adapter mounted over a distal end of an insertion device, a clip and a first extending member. The clip includes jaws movable between an insertion configuration, with the jaws separated and an initial deployed configuration with the jaws drawn together. The clip is biased toward the initial configuration. The first jaw includes a connection element and a first member releasably coupled to the first jaw connection element permits movement of the adapter relative to the clip while the first member remains coupled to the clip to enhance visual observation of the clip. The first member retracts the clip proximally over the adapter so that the clip is forced open as the clip is retracted over the adapter freeing the clip from tissue on which it had been clipped.

Abstract: A tissue moving device and apparatus with an expansion section including a plurality of elongated expansion elements shiftable from a delivery configuration to an expanded configuration. The elongated expansion elements may be separately and independently shiftable to allow various expansion configurations. The elongated expansion elements may have an end coupled to a support which is segmented into a plurality of support segments, each independently movable to allow independent shifting of the associated elongated expansion element with respect to the other elongated expansion elements. The expansion section may be mounted over a shaft, such as a shaft of a cutting device, or a shaft with a lumen through which a cutting device is axially translatable.

Abstract: A device for delivering an agent includes a valve assembly including an enclosure for storing the agent, an agitation mechanism rotatably disposed inside the enclosure, and a tube disposed inside the enclosure and extending through the agitation mechanism. The tube includes a channel having a longitudinal length defined between a first opening at a first end of the tube and a second opening at a second end of the tube. The agitation mechanism is configured to direct a fluid received in the enclosure towards the agent stored therein in response to rotating about the tube, thereby agitating the agent within the enclosure. The tube is configured to receive a mixture of the fluid and the agent at the second opening and direct the mixture through the channel for delivery out of the enclosure via the first opening.

Abstract: Anatomical obstruction extraction devices and associated methods are disclosed herein. Example anatomical obstruction extraction devices may include a first elongate shaft including a first expandable portion and a first proximal portion extending in a proximal direction from the first expandable portion. The first expandable portion may include one or more elongate support elements. A first actuator may be provided and adapted to actuate the first expandable portion to adjust between an elongate configuration and an expanded configuration. A second elongate shaft may be disposed concentrically about the first elongate shaft, and may include a second expandable portion connected and/or otherwise coupled to one or more second actuators. The one or more second actuators may act upon and/or actuate the second expandable portion to adjust between an elongate configuration and an expanded configuration.

Abstract: A medical device for insertion into a body may include a handle assembly including a handle body and a ball joint; a sensor assembly configured to electronically communicate with a magnet; a body extending longitudinally from the handle assembly; an articulation portion coupled to a distal end of the body, wherein the articulation portion includes a magnetic material; and an end effector coupled to a distal end of the articulation portion. The articulation portion may be configured to move upon application of a magnetic field from the magnet.

Abstract: A medical device is adapted to seal around elongate shafts of varying diameter therethrough. The medical device includes a plurality of elastomeric sealing members together defining a variable dimension aperture, a chuck body, and a chuck ring that is rotatably secured relative to the chuck body. The medical device is adapted such that rotating the chuck ring in a first direction causes the plurality of elastomeric sealing members to move closer together, thereby reducing a size of the variable dimension aperture, and rotating the chuck ring in a second direction causes the plurality of elastomeric sealing members to move farther apart, thereby increasing a size of the variable dimension aperture.

Abstract: A device for delivering an agent includes a valve assembly including a cavity for storing the agent and an agitation mechanism movably disposed inside the cavity. An inlet conduit fluidly coupled to a fluid source and the valve assembly. An outlet conduit fluidly coupled to the valve assembly, wherein the inlet and outlet conduit are each in fluid communication with the cavity. The agitation mechanism is configured to agitate the agent within the cavity in response to the agitation mechanism moving inside the cavity. The valve assembly is configured to urge the agitation mechanism to move inside the cavity in response to receiving a fluid from the fluid source via the inlet conduit, combine the fluid with the agent within the cavity in response to the agitation mechanism moving inside the cavity, and deliver a combination of the agent and the fluid out of the cavity through the outlet conduit.

Abstract: A medical device adaptor may comprise a distal portion, including a cap configured to be removably affixed to a distal end of a medical device and a channel extending through a lumen of the cap. The channel may be in fluid communication with a working channel of the medical device upon removably affixing the cap to the distal end of the medical device. The adaptor may further comprise a proximal portion including an actuator having a lumen. The actuator may be removably affixed to a proximal end of the medical device, such that the lumen of the proximal portion is configured to be in fluid communication with the working channel of the medical device. The medical device adaptor also may include one or more wires extending between the proximal portion and the distal portion. The one or more wires may be configured to articulate the channel of the distal portion.