Abstract: A clipping system includes an adapter configured to be mounted over an insertion device and a clip including first and second jaws movable between an insertion configuration and an initial deployed configuration. A first extending member is releasably coupled to the clip and movably connected to the adapter to permit a movement of the clip relative to the adapter from the insertion configuration to the initial deployed configuration. The first extending member is configured to permit withdrawal of the adapter away from the clip to place the system in a review configuration to enhance a visual observation of the clip. The first extending member is operable to retract the clip over the adapter so that the clip is forced open, freeing the clip from tissue on which it has been clipped. The first extending member is configured to release the clip therefrom in a final deployed configuration.

Abstract: An assembly of a medical delivery device includes an inner sleeve including a flange at a proximal end. The flange includes one or more through holes. The assembly also includes an outer sleeve movably coupled to the inner sleeve. A distal tip of the outer sleeve includes a plurality of openings for delivering an adhesive to a treatment site. The assembly further includes a cavity formed between the inner sleeve and the outer sleeve and configured to hold the adhesive prior to the delivering. The assembly yet further includes one or more actuators connected to a proximal end of the outer sleeve and extended via the one or more through holes to a handle of the medical delivery device. Actuation of the one or more actuators moves one of the inner sleeve or the outer sleeve relative to the other to cause the delivering of the adhesive.

Abstract: A medical device includes a handle including a main body and a movable body, a sheath element coupled to the handle, an actuation element disposed within the sheath element, an end cap configured to be coupled to a distal end of another medical device, and a patch positioned on the end cap and coupled to the actuation element. The patch includes a mesh and an expandable structure coupled to the mesh. The expandable structure is configured to be coupled to the actuation element, and the expandable structure is further configured to cause the mesh to retract and expand.

Abstract: A medical device includes a handle with a primary actuator and one or more secondary actuators, an end cap configured to be coupled to a distal end of another medical device and including stationary and movable portions, one or more patches that are coupled to the movable portion, one or more control elements coupling the primary actuator to the movable portion; and one or more actuation elements. The one or more actuation elements extend from the one or more secondary actuators to a position between a portion of the one or more patches and the movable portion of the end cap. Movement of the primary actuator moves the movable portion of the end cap relative to the stationary portion of the end cap, and movement of the one or more secondary actuators at least partially deploys the one or more patches from the movable portion of the end cap.

Abstract: A medical device includes a handle, an end cap, and a patch. The handle includes a movable body and a stationary body. The movable body includes an actuation member. The end cap is configured to be coupled to a distal end of a scope. The patch is movable relative to the end cap. The patch is coupled to the movable body via one or more control elements such that movement of the movable body extends the patch from the end cap. The patch is further coupled to the actuation member via one or more actuation elements such that movement of the actuation member extends, bows, or bends the one or more actuation elements to at least partially deploy the patch.

Abstract: A medical device, comprising a handle, wherein the handle includes a movable body and a stationary body; an end cap, the end cap comprising an inner cap and an outer cap, wherein the inner cap is coupled to the movable body by a control element such that movement of the movable body relative to the stationary body extends the inner cap relative to the outer cap; and a patch disposed between the inner cap and the outer cap such that movement of the inner cap relative to the outer cap at least partially deploys the patch.

Abstract: A medical device that includes a handle including a plurality of actuators. The handle defines a longitudinal axis extending through a distal end of the handle. The device includes a shaft extending from the handle and an end effector at a distal end of the shaft. A first actuator of the plurality of actuators is configured to actuate the end effector in response to translation of the first actuator relative to the handle along an axis parallel to the longitudinal axis. A second actuator of the plurality of actuators is configured to deflect the end effector relative to the shaft in response to pivoting the second actuator about an axis transverse to the longitudinal axis. A third actuator of the plurality of actuators is configured to rotate the end effector relative to the shaft in response to rotation of the third actuator relative to the handle about the longitudinal axis.

Abstract: A device includes an elongated hollow member having an open distal end for receiving tissue therein and at least one exterior groove for loading at least one ligation band thereon. The device also includes a band deployment sleeve slidable over the exterior of the hollow member and configured to move from a radially expanded position to a radially contracted position in which, when the band deployment sleeve slides longitudinally over the hollow member, the distal portion engages the at least one ligation band. A closing sleeve slidable over the exterior of the band deployment sleeve is configured to constrain the distal portion from the radially expanded position into the radially contracted position. Retracting the closing sleeve proximally over the distal portion of the band deployment sleeve releases the distal portion from the radially contracted position into the radially expanded position.

Abstract: A medical device includes opposing first and second end effectors coupled together to move from an open configuration to a closed configuration, a first link with a distal end pivotally connected to a proximal end of the first end effector, the first link including a first slot at a proximal end of the first link, a second link with a distal end pivotally connected to a proximal end of the second end effector, and a first actuator pin slidable within the first slot.

Abstract: A guidewire assembly may include a handle assembly including: a handle body; a shaft extending through the handle body; and an actuator. The guidewire assembly may further include a tube extending distally from the handle assembly and including a proximal portion and a distal portion; and an interior body extending from the handle assembly through the tube to the distal portion of the tube, wherein the interior body is coupled to the shaft. The shaft may be configured to move longitudinally through the handle body as the actuator is rotated to move interior body longitudinally through the tube.

Abstract: A medical device that includes a handle, a shaft extending distally from the handle and defining a lumen, and an actuator disposed in the shaft and including a distal tip. The actuator and the distal tip are movable relative to the lumen. The medical device includes an expandable member having an inner cavity. The actuator is configured to engage the expandable member when moving distally relative to the lumen and in response to the distal tip entering the inner cavity. The actuator is configured to disengage the expandable member when moving proximally relative to the lumen and in response to the distal tip exiting the inner cavity.

Abstract: A medical device that includes: a first handle coupled to a first sheath; a second handle coupled to a second sheath, wherein at least a portion of the first sheath is disposed within a lumen of the second sheath; and a patch. In a first configuration, the first handle and the second handle may be separated by a first distance, and the patch may be disposed between a distal portion of the first sheath and a distal portion of the second sheath. In a second configuration, the first handle and the second handle may contact one another or may be separated by a second distance, wherein the second distance is smaller than the first distance, and wherein a distalmost end of the second sheath is proximal of a proximal end of the patch.

Abstract: A medical device adaptor may comprise a distal portion, including a cap configured to be removably affixed to a distal end of a medical device and a channel extending through a lumen of the cap. The channel may be in fluid communication with a working channel of the medical device upon removably affixing the cap to the distal end of the medical device. The adaptor may further comprise a proximal portion including an actuator having a lumen. The actuator may be removably affixed to a proximal end of the medical device, such that the lumen of the proximal portion is configured to be in fluid communication with the working channel of the medical device. The medical device adaptor also may include one or more wires extending between the proximal portion and the distal portion. The one or more wires may be configured to articulate the channel of the distal portion.

Abstract: A clipping system includes a clip, extending and control members and an endcap mounted on an insertion device. A planar body of the clip includes first and second cut-outs defining fingers. The control members slide within extending members to releasably couple to the clip so that movement the control members moves the clip between an insertion configuration, an initial deployed configuration and a review configuration in which the end cap is withdrawn proximally away from the clip to enhance visual observation of the clip. The control member is operable to retract the clip proximally over the end cap toward the insertion configuration so that the fingers are forced open as the clip is retracted over the end cap, freeing the clip from tissue on which it had been clipped to reposition the clip if necessary.

Abstract: A system includes a clip, a first control member, and an adapter including a channel extending from a proximal end to a distal end. The clip includes a base portion mounted over a periphery of the adapter and arms extending distally from the portion. The arms are movable relative to one another between insertion and initial deployed configurations. The first member is releasably coupled to the portion and is movably connected to the adapter so that a longitudinal movement of the first member relative to the adapter moves the clip between the insertion configuration, the initial deployed configuration, and a review configuration. The first member is operable to retract the clip proximally over the adapter toward the insertion configuration so that the arms is forced open as the clip is retracted over the adapter freeing the clip from tissue on which it had been clipped.

Abstract: Medical devices and methods are disclosed. An example medical device for accessing a body lumen along a biliary and/or pancreatic tract may include an elongated member having a distal end and a proximal end. The medical device may have a flexible distal tip. The flexible tip may be steerable by applying tension to one or more steering wires extending between the distal tip and a handle at a proximal end of the medical device. The medical device may be a sphincterotome.

Abstract: A device includes a catheter extending longitudinally from a proximal end to a distal end and including a lumen and a grasper. The grasper includes jaws connected such that the jaws are movable between an open configuration and a closed configuration. Also, the device includes a control member connected to the grasper so that a longitudinal movement of the member relative to the catheter moves the grasper between the configurations and a proximal interface including a piston connected to the proximal end so that, when the grasper is moved toward the closed configuration, the piston applies a negative pressure through the catheter to draw a separated portion of thrombus proximally therethrough.

Abstract: A medical assembly that includes a medical device including a handle having an actuator, a shaft extending distally from the handle, and a sensor at a distal end of the shaft. The distal end of the shaft is coupled to the actuator by a wire extending through the shaft, and the sensor is configured to measure data indicative of the distal end of the shaft moving from a first position to a second position. The actuator is configured to articulate the distal end of the shaft based on the data measured by the sensor to move the distal end from the second position to the first position.

Abstract: A clipping system includes an adapter, a clip and a first extending member. The clip includes first and second jaws which are movable between an insertion configuration and an initial deployed configuration. The jaws are biased toward the initial configuration. The first member is releasably coupled to the clip and movably connected to the adapter. The first member includes a distal end releasably coupled to the first jaw such that longitudinal movement of the first member relative to the adapter moves the clip between the insertion configuration, the initial configuration and a review configuration. The first member is operable to retract the clip proximally over the adapter so that the clip is forced open as the clip is retracted over the adapter. A first releasable link connects the first member to the clip and releases when the first member is subject to a force exceeding a predetermined threshold value.

Abstract: A clipping system for treating tissue including an adapter, a clip, an extending member and a control wire. The adapter couplable to an insertion device via steering members. The steering members extend alongside the insertion device and connect to the adapter to steer the adapter between a first position and a second position. The clip mounted over the adapter. The clip includes first and second jaws connected to one another and movable between an insertion configuration and an initial deployed configuration. The extending member slidably received within one of the steering members. The control wire slidably received within the extending member and extends through the first jaw such that simultaneous longitudinal movement of the control wire and the extending member relative to the adapter moves the clip between the insertion configuration, the initial deployed configuration, and a review configuration in which the clip is separated from the adapter.