Abstract: An applicator device or dispenser includes an applicator tip assembly and a housing which may, in some examples, have a reservoir for containing a product, such as a cosmetics product or a medicinal product. The applicator tip assembly may be coupled to the housing and may comprise a thermal storage applicator portion having an application face for applying the product to a surface, the thermal storage applicator portion being made from a material that is capable of storing and retaining and/or transferring thermal energy during application of the product. The applicator tip assembly may further comprise a main body portion having a product delivery passageway extending through the main body portion for dispensing a product to the application face of the thermal storage applicator portion, the main body portion configured to at least partially enclose the thermal storage applicator portion at a periphery of the thermal storage applicator portion.

Abstract: Illustrative applicators include a roller controllably coupled to a reservoir by a wicking agent such as a felt applicator insert. A cap for the applicator is also provided. The action of the cap being placed over the roller brings the roller into contact with the wicking agent, applying product contained in the reservoir to the roller. Removing the cap causes the roller to move out of contact with the wicking agent, allowing a quantity of product applied to the roller while the cap is on the applicator to be used.

Abstract: The invention relates to fused piperidine amides useful as inhibitors of ion channels for the treatment of pain. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.

Abstract: The present invention features a compound of formula I: or a pharmaceutically acceptable salt thereof, where R1, R2, R3, W, X, Y, Z, n, o, p, and q are defined herein, for the treatment of CFTR mediated diseases, such as cystic fibrosis. The present invention also features pharmaceutical compositions, method of treating, and kits thereof.

Abstract: Containers for distributing products are disclosed. The containers comprise a bottle having at least one sidewall and defining a cavity therein. The bottle has at least one opening. The containers also include an actuator comprising at least one sidewall defining a cavity therein. The bottle also includes a tip including an orifice. The orifice is configured to dispense product therethrough. The actuator is positioned between the bottle and the tip.

Abstract: Cosmetics packaging and applicators including a gel based tip are described. Gel applicators may or may not be provided with a through-hole. In various embodiments, the gel may be a stand-alone gel or may be encapsulated in a membrane. The gel applicator provides a soft feel and may have cooling effect as well. In some embodiments, the applicator is mounted to a platform or a hollow insert and coupled to a container housing the cosmetics product.

Abstract: An applicator device or dispenser includes an applicator tip assembly and a housing which may, in some examples, have a reservoir for containing a product, such as a cosmetics product or a medicinal product. The applicator tip assembly may be coupled to the housing and may comprise a thermal storage applicator portion having an application face for applying the product to a surface, the thermal storage applicator portion being made from a material that is capable of storing and retaining and/or transferring thermal energy during application of the product. The applicator tip assembly may further comprise a main body portion having a product delivery passageway extending through the main body portion for dispensing a product to the application face of the thermal storage applicator portion, the main body portion configured to at least partially enclose the thermal storage applicator portion at a periphery of the thermal storage applicator portion.

Abstract: An applicator device or dispenser includes a stone applicator tip and a housing which may, in some examples, have a reservoir for containing a product, such as a cosmetics product or a medicinal product. The stone tip comprises a material that is capable of storing and retaining and/or transferring thermal energy during application of the product.

Abstract: The modular electrical wiring device includes an electrical wiring device and an external plug that is electrically coupled by one or more wires to the wiring device. The modular plug is releasably coupled to a connector in a male-female relationship. Both the modular plug and connector include internal contacts for electrically coupling one to the other. The connector is electrically coupled to and directly terminates one or more building wires, which are used to provide power to one or more of the wiring devices. The external plug is removably coupled to the connector to provide electrical power to the wiring device by establishing and electrical pathway from a source of electrical power, through the building wires, the connector and the modular plug to the wiring device.

Abstract: The modular electrical wiring device includes an electrical wiring device and an external plug that is electrically coupled by one or more wires to the wiring device. The modular plug is releasably coupled to a connector in a male-female relationship. Both the modular plug and connector include internal contacts for electrically coupling one to the other. The connector is electrically coupled to and terminates one or more building wires, which are used to provide power to one or more of the wiring devices. The external plug is removably coupled to the connector to provide electrical power to the wiring device by establishing and electrical pathway from a source of electrical power, through the building wires, the connector and the modular plug to the wiring device.

Abstract: The modular electrical wiring device includes an electrical wiring device and an external plug that is electrically coupled by one or more wires to the wiring device. The modular plug is releasably coupled to a connector in a male-female relationship. Both the modular plug and connector include internal contacts for electrically coupling one to the other. The connector is electrically coupled to and terminates one or more building wires, which are used to provide power to one or more of the wiring devices. The external plug is removably coupled to the connector to provide electrical power to the wiring device by establishing and electrical pathway from a source of electrical power, through the building wires, the connector and the modular plug to the wiring device.

Abstract: The modular electrical wiring device includes an electrical wiring device and an external plug that is electrically coupled by one or more wires to the wiring device. The modular plug is releasably coupled to a connector in a male-female relationship. Both the modular plug and connector include internal contacts for electrically coupling one to the other. The connector is electrically coupled to and directly terminates one or more building wires, which are used to provide power to one or more of the wiring devices. The external plug is removably coupled to the connector to provide electrical power to the wiring device by establishing and electrical pathway from a source of electrical power, through the building wires, the connector and the modular plug to the wiring device.

Abstract: A method for building a language for a knowledge base correspondingly to the observation of facts in the world includes describing by a user a world representation by building an ontology, translating the description into restrictions corresponding to the user's prescriptions, observing errors between objects and actions present in an environment and in the prescriptions, and adapting the ontology or the system behaviour in such a way that the errors are moved off.