Abstract: Systems, methods, and devices for analyzing small volumes of fluidic samples, as a non-limiting example, less than twenty microliters are provided. The devices are configured to make a first sample reading, for example, measure an energy property of the fluid sample, for example, osmolality, make a second sample reading, for example, detecting the presence or concentration of one or more analytes in the fluid sample, or make both the first sample reading and the second sample reading, for example, measuring the energy property of the fluid sample as well as detecting the presence or concentration of one or more analytes in the fluid sample.

Abstract: A vehicle for use in an amusement park ride with upright passenger seating. The vehicle includes a vehicle body and a seat assembly including a seat pan provided in the vehicle body between a front end and a rear end of the vehicle body. The vehicle further includes a passenger restraint system with: (a) a lap bar assembly; (b) a lap bar mount pivotally supporting the lap bar assembly within the vehicle body to pivot about a lap bar rotation axis passing between the seat pan and the front end of the vehicle body; (c) a side leg shield; and (d) a shield articulating assembly concurrently pivoting the side leg shield about a shield rotation axis from an open to a closed position with a pivoting of the lap bar assembly about the lap bar rotation axis from a disengage to an engaged position.

Abstract: A system for forming a tendon sleeve on an atmospheric balloon is described herein, the system comprising a coupling assembly including a seam coupling mechanism that forms a seam joint between a first gore panel and a second gore panel, the seam joint is spaced from respective first and second lateral edges of the first and second gore panels to form first and second edge flanges, and an edge coupling mechanism that forms an edge joint between the first and second edge flanges and closes a tendon sleeve, the edge joint spaced from the seam joint, the tendon sleeve includes a tendon sleeve passage between the seam joint and the edge joint and between the first and second edge flanges. The system also includes a tendon positioning mechanism that positions a tendon within the tendon sleeve passage. A tendon sleeve formed by this system is also described herein.

Abstract: A cam plate for use with a pump includes at least one camming surface configured to enable an impeller to rotate in a first direction and substantially prevent the impeller from rotating in a second direction opposite the first direction. A ring recess is defined in the cam plate. The ring recess is configured to receive at least a portion of a cam ring that is configured to rotate within the ring recess. A follower recess is at least partially defined by the at least one camming surface and extends from the ring recess. The follower recess is configured to receive at least one cam follower therein.

Abstract: Embodiments of the invention provide a method of managing content filters within a three dimensional (3D) immersive environment without compromising the visual and interactive integrity of the environment itself. In one embodiment, content may be selectively filtered by dynamically categorizing content within the immersive environment by tracking baseline avatar patterns. Once a pattern is identified between a given content element (i.e., some element of the environment which an avatar may interact with) and avatar interactions (or lack of interactions) with that content element, a filter may be defined and applied to that content element.

Abstract: A vehicle for use in an amusement park ride with upright passenger seating. The vehicle includes a vehicle body and a seat assembly including a seat pan provided in the vehicle body between a front end and a rear end of the vehicle body. The vehicle further includes a passenger restraint system with: (a) a lap bar assembly; (b) a lap bar mount pivotally supporting the lap bar assembly within the vehicle body to pivot about a lap bar rotation axis passing between the seat pan and the front end of the vehicle body; (c) a side leg shield; and (d) a shield articulating assembly concurrently pivoting the side leg shield about a shield rotation axis from an open to a closed position with a pivoting of the lap bar assembly about the lap bar rotation axis from a disengage to an engaged position.

Abstract: Provided herein is a method comprising: producing a first complex by annealing: a first nucleic acid comprising, in order, a first unique sequence, a first central sequence and a second unique sequence; and a second nucleic acid comprising, in order, said second unique sequence, a second central sequence and a third unique sequence; wherein the first, second and third unique sequences do not hybridize with each other; subjecting said first complex to multiple rounds of primer extension to extend the first and second nucleic acids using each other as a template, thereby producing a first product molecule that contains, in order, the first unique sequence, the first central sequence, the second unique sequence, the second central sequence and the third unique sequence; and circularizing said first product molecule by intramolecularly ligating the ends of said product molecule together. Kits and compositions relating to the method are also provided.

Abstract: A fan apparency arrangement for an appliance is disclosed. The appliance has a chamber with a first port and a second port. The arrangement includes a fan for moving air in or out of the chamber, and a sail switch disposed adjacent to the second port. When activated, the fan moves air in or out of the chamber through the first port to create a pressure difference between an inside and an outside of the chamber. The pressure difference causes the sail switch to change position and signal that the fan is activated. An appliance incorporating such a fan apparency arrangement is also disclosed.

Abstract: A camera accessory includes one or more kinematic sensor(s), such as accelerometer(s) and/or angular rate sensor(s), an actuator, and a coupling mechanism to adjust the orientation of a horizontal image plane of an image sensor of a digital video camera independent of the orientation of the camera housing of the digital video camera.

Abstract: This disclosure provides, among other things, a method of combining nucleic acid fragments, comprising: (a) providing two double-stranded DNA molecules with a common sequence, wherein the common sequence is at the end of each molecule; (b) nicking one strand in the common sequence of both molecules at a respective nicked site; (c) moderately denaturing both molecules to remove a single-stranded fragment from the nicked site to one end of each molecule, wherein the single-stranded fragment includes the common sequence in part or in whole, resulting in an overhanging sequence in each molecule, and the overhanging sequences in both molecules are complementary to each other; (d) allowing the overhanging sequences of both molecules to anneal to each other, and ligating the molecules. Alternative ways for performing the method are also provided.

Abstract: Provided herein is a method for producing a population of oligonucleotides that has reduced synthesis errors. In certain embodiments, the method comprises: a) obtaining an initial population of hairpin oligonucleotide molecules that each comprise a double-stranded stem region and a loop region; b) contacting the double-stranded region of the hairpin oligonucleotide molecules with a mismatch binding protein; and c) eliminating any molecules that bind to the mismatch binding protein, thereby producing a population of oligonucleotides that has reduced synthesis errors. A kit and a composition for performing the method are also provided.

Abstract: A method for fragmenting a genome is provided. In certain embodiments, the method comprises: (a) combining a genomic sample containing genomic DNA with a plurality of Cas9-gRNA complexes, wherein the Cas9-gRNA complexes comprise a Cas9 protein and a set of at least 10 Cas9-associated guide RNAs that are complementary to different, pre-defined, sites in a genome, to produce a reaction mixture; and (b) incubating the reaction mixture to produce at least 5 fragments of the genomic DNA. Also provided is a composition comprising at least 100 Cas9-associated guide RNAs that are each complementary to a different, pre-defined, site in a genome. Kits for performing the method are also provided. In addition, other methods, compositions and kits for manipulating nucleic acids are also provided.

Abstract: Apparatuses for use in plants for processing methane, the apparatuses comprising a plurality of reaction modules each including a plurality of Fischer-Tropsch reactors operable to convert a gaseous mixture including carbon monoxide and hydrogen to a liquid hydrocarbon. Each module may be disconnected and taken away for servicing while allowing the plant to continue to operate. In some of the apparatuses, each Fischer-Tropsch reactor comprises a plurality of metal sheets arranged as a stack to define first and second flow channels for flow of respective fluids, the channels being arranged alternately to ensure good thermal contact between the fluids in the channels.

Abstract: Methane reacts with steam generating carbon monoxide and hydrogen in a first catalytic reactor; the resulting gas mixture undergoes Fischer-Tropsch synthesis in a second catalytic reactor. In the steam/methane reforming, the gas mixture passes through a narrow channel having mean and exit temperatures both in the range of 750° C. to 900° C., residence time less than 0.5 second, and the channel containing a catalyst, so that only reactions having comparatively rapid kinetics will occur. Heat is provided by combustion of methane in adjacent channels. The ratio of steam to methane may be about 1.5. Almost all methane will undergo the reforming reaction, almost entirely forming carbon monoxide. After Fischer-Tropsch synthesis, the remaining hydrogen may be fed back to the combustion channels. The steam for the reforming step may be generated from water generated by the chemical reactions, by condensing products from Fischer-Tropsch synthesis and by condensing water vapor generated in combustion.

Abstract: A method, system, and computer usable program product for improving processor performance during power supply failure are provided in the illustrative embodiments. A throttled condition of a processor is detected in a data processing system. A voltage of the electrical power being provided to the processor is reduced. The processor is un-throttled. Additionally, a frequency of electrical power being provided to the processor may also be reduced. A determination is made whether a condition that caused the throttling has been corrected. In response to the condition having been corrected, the frequency is returned to normal frequency and the voltage is returned to normal voltage. The reducing the frequency operation and reducing the voltage operation may each be performed by distinct components communicating over a data network external to the data processing system.

Abstract: A reactor module for Fischer-Tropsch synthesis having a generally rectangular reactor block with a stack of plates defining flow channels for coolant and flow channels for the synthesis reaction arranged alternately in the block. The synthesis flow channels extend in a generally vertical direction between upper and lower faces of the reactor block and are defined by plates in combination with either bars or sheets such that each channel is of width no more than 200 mm. The coolant flow channels are oriented in the same direction, and communicate through distributor chambers with inlet and outlet ports at side faces of the reactor block. A plant may contain a multiplicity of such reactor modules operating in parallel, the modules being interchangeable and replaceable. The temperature control is enhanced by allowing the coolant flow to be parallel to the synthesis gas flow.

Abstract: A heat pump water heater and systems and methods for its control are disclosed. The systems are configured to heat water within a water storage tank of a heat pump water heater wherein a controller within the system is operatively connected to a plurality of heat sources including at least one electric heating element and a heat pump and sensors in order to selectively energize one of the plurality of heat sources. The controller is configure to process data representative of the temperature of water within the tank near the top of the water storage tank, and rate of water flowing out of the water storage tank, in order to automatically selectively energize the heat sources. The selection of heat sources by the controller is determined by a mode of operation selected by the user and the data processed by the controller in view of the selected mode of operation.

Abstract: A gas burner for a cooking appliance having a base portion and a side wall extending from the base portion. A cap is disposed on the side wall. The cap includes a substantially conical interior surface facing the base portion. The substantially conical interior surface is configured to substantially eliminate creation of turbulent flow eddies in a gaseous fuel mixture passing through the gas burner.

Abstract: A rotor assembly for use with a pump includes an impeller having an impeller plate and a cam ring extending from a first surface of the impeller plate and a cam plate positioned proximate the impeller plate. The cam plate includes at least one camming surface. At least one cam follower is positioned between the cam ring and the at least one camming surface. The at least one cam follower is configured to cooperate with at least one of the cam ring and the at least one camming surface to enable the impeller to rotate in a first direction and substantially prevent the impeller from rotating in a second direction opposite the first direction.

Abstract: A cam plate for use with a pump includes at least one camming surface configured to enable an impeller to rotate in a first direction and substantially prevent the impeller from rotating in a second direction opposite the first direction. A ring recess is defined in the cam plate. The ring recess is configured to receive at least a portion of a cam ring that is configured to rotate within the ring recess. A follower recess is at least partially defined by the at least one camming surface and extends from the ring recess. The follower recess is configured to receive at least one cam follower therein.