Patents by Inventor Deyuan Zhang
Deyuan Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11969368Abstract: A lumen stent preform is provided using a plasma nitriding technology, a preparation method thereof, a method for preparing a lumen stent by using the preform, and a lumen stent obtained according to the method. The preform is manufactured by using pure iron or an iron alloy containing no strong nitrogen compound, has a hardness of 160-250HV0.05/10, and has a microstructure that is a deformed structure having a grain size scale greater than or equal to 9 or a deformed structure after cold machining. Alternatively, the preform is an iron alloy containing a strong nitrogen compound, and has a microstructure that is a deformed structure having a grain size scale greater than or equal to 9 or a deformed structure after cold machining. The lumen stem preform meets the requirements of a conventional stent for radial strength and plasticity, so that plasma nitriding is applicable to commercial preparation of a lumen stent.Type: GrantFiled: July 7, 2022Date of Patent: April 30, 2024Assignee: BIOTYX MEDICAL (SHENZHEN) CO., LTD.Inventors: Deyuan Zhang, Xianmiao Chen, Wenjiao Lin, Xiangdong Liu
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Publication number: 20240042108Abstract: The present invention relates to the technical field of medical devices, and in particular to an orthopedic internal fixation implant medical device, including an iron matrix and a filling material including polylactic acid and an alkaline substance. The polylactic acid has a weight-average molecular weight of Mw kDa, the alkaline substance includes a metal element, the mass ratio of the metal element in the alkaline substance to the polylactic acid is p, and the p and the Mw satisfy a formula of 2Mw{circumflex over (?)}?0.8?p?30Mw{circumflex over (?)}?0.5. The orthopedic internal fixation implant medical device, with good mechanical properties, can control local pH values and induce bone healing.Type: ApplicationFiled: December 28, 2021Publication date: February 8, 2024Applicant: BIOTYX MEDICAL (SHENZHEN) CO., LTD.Inventors: Deyuan Zhang, Haiping Qi
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Patent number: 11819591Abstract: An iron-based alloy absorbable and implantable medical device for internal fixation. A substrate includes an iron-based alloy and degradable polymer. The mass ratio of the iron-based alloy to the degradable polymer is between 1:4 and 4:1. The weight-average molecular weight of the degradable polymer is between 150000 to 3000000, and the polydispersity index thereof is between 1 and 6. The device further includes antioxidants. The iron-based alloy is used as a load-bearing framework or reinforcement phase of the device. By adjusting the mass ratio of the iron-based alloy to the degradable polymer and the combination mode thereof, the corrosion rate of the iron-based alloy in the late period of the implantation is accelerated, and the quantity of corrosion products poorly soluble in the iron-based alloy is reduced. Adding antioxidants to the device further reduces the quantity of the corrosion products poorly soluble in the iron-based alloy.Type: GrantFiled: June 27, 2016Date of Patent: November 21, 2023Assignee: Biotyx Medical (Shenzhen) Co., Ltd.Inventors: Wenjiao Lin, Deyuan Zhang
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Publication number: 20230256142Abstract: An absorbable implantable medical device made of iron-based alloy, including a base made of iron-based alloy and a complex, wherein the complex includes a complexing agent. In a physiological solution, the base made of iron-based alloy can react with the complexing agent to generate a water-soluble iron complex having solubility in the physiological solution of no less than 10 mg/L. A corrosion product generated after the absorbable implantable medical device made of iron-based alloy is implanted in a human body can be quickly metabolized/absorbed by the body.Type: ApplicationFiled: April 21, 2023Publication date: August 17, 2023Applicant: Biotyx Medical (Shenzhen) Co., Ltd.Inventors: Deyuan ZHANG, Haiping QI, Wenjiao LIN, Gui ZHANG, Li QIN
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Patent number: 11684692Abstract: An absorbable iron-based instrument is provided having an iron-based substrate, a zinc-containing protector in contact with the iron-based substrate, and a degradable polyester in contact with the iron-based substrate and/or the zinc-containing protector. The range of the ratio of the mass of the zinc-containing protector to the mass of the iron-based substrate is 1:200 to 1:2. In the degradable polyester, the mass fraction of a low-molecular-weight part with a molecular weight of less than 10,000 is less than or equal to 5%; alternatively, in the degradable polyester, the mass fraction of a residual monomer is less than or equal to 2%.Type: GrantFiled: December 19, 2017Date of Patent: June 27, 2023Assignee: Lifetech Scientific (Shenzhen) Co. Ltd.Inventors: Hongtao Sun, Deyuan Zhang, Jun Hu, Liping Chen
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Publication number: 20230142931Abstract: The present invention relates to a zinc-containing medical device, including a zinc-containing matrix and a polylactic acid coating arranged on the zinc-containing matrix. The polylactic acid coating has a thickness of x ?m; and when x and the weight-average molecular weight Mn (kDa) of polylactic acid satisfied the following formula: ( - b + b 2 - 4 ? a ? c ) / 2 ? a - 2 ? x ? ( - b + b 2 - 4 ? a ? c ) / 2 ? a + 2 , the corrosion rate of zinc in the matrix is relatively small, sufficient mechanical properties can be maintained within the repair period, and the biological risk is relatively low. When the polylactic acid is poly-racemic lactic acid, a=0.0336 ln(Mn)?0.1449, b=?0.472 ln(Mn)+2.1524, and c=1.1604 ln(Mn)?5.7128; and when the polylactic acid is poly-L-lactic acid, a=?0.006 ln(Mn)+0.03441, b=0.0648 ln(Mn)?0.3662, and c=?0.162 ln(Mn)+0.7847.Type: ApplicationFiled: April 7, 2021Publication date: May 11, 2023Applicant: BIOTYX MEDICAL (SHENZHEN) CO., LTD.Inventors: Deyuan Zhang, Haiping Qi, Wenjiao Lin
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Patent number: 11623028Abstract: An absorbable implantable medical device made of iron-based alloy, including a base made of iron-based alloy and a complex, wherein the complex includes a complexing agent. In a physiological solution, the base made of iron-based alloy can react with the complexing agent to generate a water-soluble iron complex having solubility in the physiological solution of no less than 10 mg/L. A corrosion product generated after the absorbable implantable medical device made of iron-based alloy is implanted in a human body can be quickly metabolized/absorbed by the body.Type: GrantFiled: June 14, 2016Date of Patent: April 11, 2023Assignee: Biotyx Medical (Shenzhen) Co., Ltd.Inventors: Deyuan Zhang, Haiping Qi, Wenjiao Lin, Gui Zhang, Li Qin
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Publication number: 20230041280Abstract: A luminal stent has a tube body and a skirt surrounding the tube body. The skirt has a flexible connecting section and a stent graft connected to a proximal end of the flexible connecting section. A distal end of the flexible connecting section is sealed and connected to the outer surface of the tube body. A proximal end of the stent graft is suspended and provided with a first radial support structure. When the flexible connecting section is radially compressed, at least a part of the first radial support structure is bent towards a direction distant from the tube body. Also provided is a stent system including the luminal stent. The stent system and the luminal stent can prevent type III endoleaks.Type: ApplicationFiled: October 13, 2022Publication date: February 9, 2023Applicant: Lifetech Scientific (Shenzhen) Co., Ltd.Inventors: Benhao XIAO, Deyuan ZHANG, Chang SHU, Chao YIN, Yifei WANG
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Patent number: 11547417Abstract: A left atrial appendage occluder comprises an elastic closure disc, and a supporting structure connecting with the closure disc and being located on one side of the closure disc, with the supporting structure comprising a central end connecting with the closure disc and a plurality of interconnected and bent struts, wherein at least one anchoring thorn is set near the end of at least one strut with the anchoring thorn toward the closure disc. The left atrial appendage occluder has a stable structure, a good positioning and sealing effect on the cavity wall in the left atrial appendage, and it is easy to position repeatedly; it can also be recycled before separating from a conveyor. When in surgical operation, the left atrial appendage occluder can select the position area based on the actual shape and size of the patient's left atrial appendage, so the surgical risk is lowered.Type: GrantFiled: April 2, 2019Date of Patent: January 10, 2023Assignee: Lifetech Scientific (Shenzhen) Co. Ltd.Inventors: Anning Li, Deyuan Zhang
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Patent number: 11498703Abstract: The invention discloses a system for hole making for an aircraft skin by normal positioning and locking. The hole-making system includes a posture adjustment part, a normal positioning and locking part and a hole-making execution part. This system solves the problems that the device in the prior art has high complexity and cumbersome positioning and does not adapt to complex curved surfaces, thereby failing to satisfy the needs of efficient hole making in different space states. In the present invention, the expansion of an outer expansion sleeve in a bottom sleeve locks a normal direction for hole making, thereby ensuring the positioning accuracy of the normal direction. An axial position is locked by the mutual cooperation of an axial positioning groove of the bottom sleeve and an axial positioning rib of the outer expansion sleeve. A hole-making auxiliary cylinder contracts to counteract part of an axial force for hole making.Type: GrantFiled: June 4, 2020Date of Patent: November 15, 2022Assignee: BEIHANG UNIVERSITYInventors: Deyuan Zhang, Shaomin Li, Yanqiang Liu, Chunjian Liu, Hui Tang, Guang Ma, Liangliang Ren
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Publication number: 20220339012Abstract: A lumen stent preform is provided using a plasma nitriding technology, a preparation method thereof, a method for preparing a lumen stent by using the preform, and a lumen stent obtained according to the method. The preform is manufactured by using pure iron or an iron alloy containing no strong nitrogen compound, has a hardness of 160-250HV0.05/10, and has a microstructure that is a deformed structure having a grain size scale greater than or equal to 9 or a deformed structure after cold machining. Alternatively, the preform is an iron alloy containing a strong nitrogen compound, and has a microstructure that is a deformed structure having a grain size scale greater than or equal to 9 or a deformed structure after cold machining. The lumen stem preform meets the requirements of a conventional stent for radial strength and plasticity, so that plasma nitriding is applicable to commercial preparation of a lumen stent.Type: ApplicationFiled: July 7, 2022Publication date: October 27, 2022Applicant: BIOTYX MEDICAL (SHENZHEN) CO., LTD.Inventors: Deyuan Zhang, Xianmiao Chen, Wenjiao Lin, Xiangdong Liu
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Patent number: 11389308Abstract: A lumen stent preform is provided using a plasma nitriding technology, a preparation method thereof, a method for preparing a lumen stent by using the preform, and a lumen stent obtained according to the method. The preform is manufactured by using pure iron or an iron alloy containing no strong nitrogen compound, has a hardness of 160-250HV0.05/10, and has a microstructure that is a deformed structure having a grain size number greater than or equal to 9 or a deformed structure after cold machining. Alternatively, the preform is an iron alloy containing a strong nitrogen compound, and has a microstructure that is a deformed structure having a grain size number greater than or equal to 9 or a deformed structure after cold machining. The lumen stent preform meets the requirements of a conventional stent for radial strength and plasticity, so that plasma nitriding is applicable to commercial preparation of a lumen stent.Type: GrantFiled: November 12, 2015Date of Patent: July 19, 2022Assignee: Biotyx Medical (Shenzhen) Co. Ltd.Inventors: Deyuan Zhang, Xianmiao Chen, Wenjiao Lin, Xiangdong Liu
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Patent number: 11173059Abstract: A tube stent includes a first tube body. The first tube body includes a first section, a second section, and a transition section located between the first section and the second section. One end of the transition section is connected to the first section, and the other end is connected to the second section. The shortening rate of the first section and the shortening rate of the second section are smaller than the shortening rate of the transition section. By using the tube stent, the pulsations of aortas are buffered by the transition section, so that vibration deformations of the tube stent are confined to the first section and the transition section, and accordingly the relative stability of the second section and branch blood vessels can be ensured, and the stimulations to walls of the branch blood vessels can be reduced.Type: GrantFiled: August 22, 2018Date of Patent: November 16, 2021Assignee: LIFETECH SCIENTIFIC (SHENZHEN) CO., LTDInventors: Deyuan Zhang, Chang Shu, Benhao Xiao, Yifei Wang
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Publication number: 20210253272Abstract: The invention discloses a system for hole making for an aircraft skin by normal positioning and locking. The hole-making system includes a posture adjustment part, a normal positioning and locking part and a hole-making execution part. This system solves the problems that the device in the prior art has high complexity and cumbersome positioning and does not adapt to complex curved surfaces, thereby failing to satisfy the needs of efficient hole making in different space states. In the present invention, the expansion of an outer expansion sleeve in a bottom sleeve locks a normal direction for hole making, thereby ensuring the positioning accuracy of the normal direction. An axial position is locked by the mutual cooperation of an axial positioning groove of the bottom sleeve and an axial positioning rib of the outer expansion sleeve. A hole-making auxiliary cylinder contracts to counteract part of an axial force for hole making.Type: ApplicationFiled: June 4, 2020Publication date: August 19, 2021Inventors: Deyuan Zhang, Shaomin Li, Yanqiang Liu, Chunjian Liu, Hui Tang, Guang Ma, Liangliang Ren
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Patent number: 11071624Abstract: An artificial heart valve stent including: a tubular stent body having an inflow side end and an outflow side end, the inflow side end and the outflow side end being opposite to each other; an inflow side skirt surrounding the external wall of the stent body; and an outflow side skirt surrounding the external wall of the stent body. In a spread state, free ends of the inflow side skirt and the outflow side skirt extend toward the inflow side end; and the inflow side skirt cooperates with the outflow side skirt to clamp heart valve tissues. The artificial heart valve stent can be steadily arranged on heart valve tissues, prolong the service life of an artificial heart valve and reduce the risk of another artificial heart valve replacement for the patient.Type: GrantFiled: March 18, 2016Date of Patent: July 27, 2021Assignee: LIFETECH SCIENTIFIC (SHENZHEN) CO., LTDInventors: Jian Zhuang, Huiming Guo, Huanlei Huang, Zhiwei Wang, Xiangdong Liu, Mingjuan Fu, Wei Jiang, Deyuan Zhang
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Patent number: 10994386Abstract: An ultrasonic peening-type integrated machining method for cutting and extrusion includes: applying transverse ultrasonic vibration or a vibration component, which is vertical to a cutting speed direction to a cutting tool on a machine tool; setting a cutting parameter and an ultrasonic vibration parameter such that a dynamic negative clearance angle is generated in a cutting procedure and a flank face of the cutting tool conducts ultrasonic peening extrusion on the surface of the workpiece; setting an extrusion overlap ratio; setting a wear standard of flank faces extruded by the cutting tool; controlling a vibration cutting trajectory phase difference of the cutting tool during two adjacent rotations; and turning on the machine tool in order to ensure that cutting and surface extrusion strengthening of the workpiece are completed in one procedure without separate strengthening procedures. The method conducts extrusion strengthening on the surface of the workpiece while cutting the workpiece.Type: GrantFiled: August 19, 2019Date of Patent: May 4, 2021Assignee: Beihang UniversityInventors: Deyuan Zhang, Zhenghui Lu, Xun Li, Xinggang Jiang, Shenliang Yang, Xiangyu Zhang, Daxi Geng
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Patent number: 10973948Abstract: An absorbable iron-based device includes an iron-based matrix and degradable polyester in contact with the surface of the iron-based matrix. The mass fraction of a low-molecular-weight part of the degradable polyester is less than or equal to 5%, and the molecular weight of the low-molecular-weight part is less than 10,000; or the mass fraction of a residual monomer in the degradable polyester is less than or equal to 2%.Type: GrantFiled: December 19, 2017Date of Patent: April 13, 2021Assignee: Biotyx Medical (Shenzhen) Co., LtdInventors: Jun Hu, Deyuan Zhang, Hongtao Sun, Liping Chen
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Patent number: 10946121Abstract: An absorbable iron-based alloy implantable medical device, including an iron-based alloy substrate and a degradable polymer coating and a zinc-containing protector which are arranged on the surface of the iron-based alloy substrate. The zinc-containing protector is selected from zinc and/or a zinc alloy, or a mixture of zinc and/or a zinc alloy and a degradable binder. The weight percentage of the zinc and/or zinc alloy in the mixture is greater than or equal to 20% and less than 100%. The zinc-containing protector is capable of delaying the corrosion of the iron-based alloy substrate during the early stage of implantation, such that the iron-based alloy substrate essentially avoids corrosion during the early stage of implantation and the clinical mechanical property requirements for the device in the early stage of implantation can be satisfied.Type: GrantFiled: June 27, 2016Date of Patent: March 16, 2021Assignee: Biotyx Medical (Shenzhen) Co., Ltd.Inventors: Ziqiang Liu, Haiping Qi, Wenjiao Lin, Deyuan Zhang
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Publication number: 20200390574Abstract: A tube stent includes a first tube body. The first tube body includes a first section, a second section, and a transition section located between the first section and the second section. One end of the transition section is connected to the first section, and the other end is connected to the second section. The shortening rate of the first section and the shortening rate of the second section are smaller than the shortening rate of the transition section. By using the tube stent, the pulsations of aortas are buffered by the transition section, so that vibration deformations of the tube stent are confined to the first section and the transition section, and accordingly the relative stability of the second section and branch blood vessels can be ensured, and the stimulations to walls of the branch blood vessels can be reduced.Type: ApplicationFiled: August 22, 2018Publication date: December 17, 2020Applicant: LIFETECH SCIENTIFIC (SHENZHEN) CO., LTDInventors: Deyuan ZHANG, Chang SHU, Benhao XIAO, Yifei WANG
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Publication number: 20200384149Abstract: An absorbable iron-based instrument is provided having an iron-based substrate, a zinc-containing protector in contact with the iron-based substrate, and a degradable polyester in contact with the iron-based substrate and/or the zinc-containing protector. The range of the ratio of the mass of the zinc-containing protector to the mass of the iron-based substrate is 1:200 to 1:2. In the degradable polyester, the mass fraction of a low-molecular-weight part with a molecular weight of less than 10,000 is less than or equal to 5%; alternatively, in the degradable polyester, the mass fraction of a residual monomer is less than or equal to 2%.Type: ApplicationFiled: December 19, 2017Publication date: December 10, 2020Applicant: Lifetech Scientific (Shenzhen) Co., Ltd.Inventors: Hongtao Sun, Deyuan Zhang, Jun Hu, Liping Chen