Abstract: An absorbable occluder (100) comprises a woven mesh (110), wherein the woven mesh (110) comprises at least two polymer filaments with different centralized degradation time periods, or comprises a polymer filament made by blending at least two polymers with different centralized degradation time periods. The absorbable occluder (100) can avoid the tissue inflammatory response caused by the polymer filaments of the woven mesh (110) centralized degrading within the same period.

Abstract: The present invention relates to a thoracic aortic covered stent (100), comprising a bare stent segment (110) and a covered stent segment (120). The bare stent segment (110) comprises a bare wave-shaped ring (111); the covered stent segment (120) has a lesser curvature side region (100c), a greater curvature side region (100a), and two opposite intermediate regions (100b) located between the lesser curvature side region (100c) and the greater curvature side region (100a) respectively; and the covered stent segment (120) comprises a first proximal wave-shaped ring (121).

Abstract: In a method for treating an aortic arch disease, after an intraoperative stent is expanded in an aorta and at least one arch branch vessel, and before the vessel is exactly anastomosed with an incision, by blocking a thoracic aorta between the incision and an arch branch vessel closest to the incision, the intraoperative stent in the thoracic aorta is also blocked, so that blood is prevented from flowing from the incision, and a proximal orifice of the intraoperative stent, and the low body perfusion may be recovered in advance, thereby reducing the circulatory arrest time of the low body perfusion and reducing the time of ischemia of visceral organs and lower limbs of a patient. Meanwhile, the flow of a cerebral perfusion through the right axillary artery may be recovered to a normal flow in advance, and the time of ischemia of the brain of the patient is reduced.

Abstract: A method for treating an aneurysm with at least one branch blood vessel branched from a diseased aorta comprises implanting an aortic stent graft and an auxiliary stent into a diseased blood vessel to isolate the aneurysm, wherein the auxiliary stent comprises a bifurcated stent graft, one end of the aortic stent graft is attached to the wall of a healthy blood vessel upstream of the aneurysm, and the auxiliary stent comprises a body portion and a branch portion communicated with the body portion, one end of the body portion is communicated with a healthy blood vessel downstream of the aneurysm, the other end of the body portion is communicated with the aortic stent graft, and the branch portion is suspended within the diseased blood vessel. A straight stent graft is advanced towards the branch portion from the location downstream of the bifurcated stent graft and deployed to communicate the branch portion and the branch blood vessel.

Abstract: A bioabsorbable medical device or a medical device component comprises an absorbable component prepared by subjecting a prefabricated component of an iron-based raw material to ion nitriding. Substance composition inside the absorbable component changes with the depth from the surface. The absorbable component comprises at least a first part and a second part. The first part surrounds the second part. Hardness of the first part is higher than hardness of the second part. An interface exists between the first part and the second part. A crack generated in the first part is impeded by the interface when extending to the second part. On the premise of ensuring radial stand strength, the bioabsorbable medical device or medical device component and a preparation method thereof reduce wall thickness of an iron-based stand, improve a stand corrosion rate and malleability, and achieve broader adaptability.

Abstract: Provided is a method for plating a biocompatible coating with nano structure on the surface of a nickel-titanium shape memory alloy, particularly a method suitable for plating a coating on the surface of medical devices made of nickel-titanium alloy. The method includes the following steps: heat treating, surface pretreating, ion sputter cleaning, depositing a pseudodiffusion layer, plating a sub-layer film, plating a pure TiN layer, and so on. The coating has the following advantages: 1) it could deform in response to the deformation of substrate without delaminating and cracking; 2) it has less resistance to the deformation of substrate; 3) it has less penetrable holes so as to reduce the dissolution of nickel into bio-body through these holes; 4) the coating has better biocompatibility compared to the substrate material.

Abstract: A degradable iron-based alloy stem comprises an iron-based alloy substrate and a degradable polymer in contact with the surface of the substrate. The weight-average molecular weight of the degradable polymer is in the range of [1, 100]*104, and the polydispersity index of the degradable polymer is in the range of (1.0. 50]. The degradable polymer is selected from a degradable polyamino acid that can generate an acidic amino acid after degradation; or a mixture of the degradable polyamino acid and a degradable polyester, or a copolymer of monomers of the two; or a mixture of the degradable polyamino acid and a degradable polymer that does not generate acidic products after degradation, or a copolymer of the monomers of the two; or a mixture of the degradable polyamino acid, the degradable polyester and the degradable polymer that does not generate acidic products after degradation, or a copolymer of monomers of the three, or a mixture of a copolymer of monomers of any two of the three with the remaining one.

Abstract: The present invention relates to a Left atrial appendage occluder comprising an elastic closure disc. The left atrial appendage occluder also comprises an elastic fixing frame connected with the closure disc and located on one side of the closure disc. The fixing frame comprises a central end connected with the closure disc and a plurality of interconnected and bent struts, wherein at least one anchor is set near the end of at least one strut with the anchor pointing toward the closure disc. The left atrial appendage occluder has a stable structure, a good positioning and sealing effect on the cavity wall in the left atrial appendage, and it is easy to position repeatedly; it can also be recycled before separating from a conveyor. When in surgical operation, the left atrial appendage occluder can select the position area based on the actual shape and size of the patient's left atrial appendage, so the surgical risk is lowered.

Abstract: A lumen stent preform is provided using a plasma nitriding technology, a preparation method thereof, a method for preparing a lumen stent by using the preform, and a lumen stent obtained according to the method. The preform is manufactured by using pure iron or an iron alloy containing no strong nitrogen compound, has a hardness of 160-250HV0.05/10, and has a microstructure that is a deformed structure having a grain size scale greater than or equal to 9 or a deformed structure after cold machining. Alternatively, the preform is an iron alloy containing a strong nitrogen compound, and has a microstructure that is a deformed structure having a grain size scale greater than or equal to 9 or a deformed structure after cold machining. The lumen stent preform meets the requirements of a conventional stent for radial strength and plasticity, so that plasma nitriding is applicable to commercial preparation of a lumen stent.

Abstract: In a method for treating an aortic arch disease, after an intraoperative stent is expanded in an aorta and at least one arch branch vessel, and before the vessel is exactly anastomosed with an incision, by blocking a thoracic aorta between the incision and an arch branch vessel closest to the incision, the intraoperative stent in the thoracic aorta is also blocked, so that blood is prevented from flowing from the incision, and a proximal orifice of the intraoperative stent, and the low body perfusion may be recovered in advance, thereby reducing the circulatory arrest time of the low body perfusion and reducing the time of ischemia of visceral organs and lower limbs of a patient. Meanwhile, the flow of a cerebral perfusion through the right axillary artery may be recovered to a normal flow in advance, and the time of ischemia of the brain of the patient is reduced.

Abstract: Disclosed is a manufacturing method of an iron-based alloy medical apparatus, comprising: nitriding the iron-based alloy preformed unit at 350-550° C. for 30-100 minutes; and ion etching the iron-based alloy preformed unit with an ion etching time of 80-110% of the nitriding time. Ion nitriding and ion etching can be performed in situ in the same equipment using this manufacture method with high production efficiency, and in the ion nitriding and ion etching process, nitrogen atoms continuously permeate the preformed unit, making the time it takes for the medical apparatus to be absorbed by the human body and both the hardness and strength of the instrument surface achieve requirements.

Abstract: The present invention relates to a thoracic aortic covered stent (100), comprising a bare stent segment (110) and a covered stent segment (120). The bare stent segment (110) comprises a bare wave-shaped ring (111); the covered stent segment (120) has a lesser curvature side region (100c), a greater curvature side region (100a), and two opposite intermediate regions (100b) located between the lesser curvature side region (100c) and the greater curvature side region (100a) respectively; and the covered stent segment (120) comprises a first proximal wave-shaped ring (121).

Abstract: A bifurcated stem graft (10) comprises a body (100) and a side branch (200) that forms an acute angle with the body (100). The side branch (200) comprises a covering film (220) and a first bare stent (240) only disposed on the covering film (220). Part of the first bare stent (240) is positioned adjacent a boundary line (230) of the body (100) and the covering film (220) and is located in a vertex angle area (250) of the acute angle. Due to the fact that part of the first bare stem (240) is attached to the vertex angle area (250), after the stem (10) is released, the self-expanded part of the first bare stent (240) enables the vertex angle area (250) of the side branch (200) to be effectively supported, the covering film is not prone to shrinkage, and a leading wire can enter easily.

Abstract: A high-speed precision interrupted ultrasonic vibration cutting method includes steps of: (1) installing an ultrasonic vibration apparatus on a machine tool, and stimulating a cutting tool to generate a transverse vibration, so as to realize varieties of machining processes; (2) realizing an interrupted cutting process by setting cutting parameters and vibration parameters to satisfy an interrupted cutting conditions; and (3) turning on the ultrasonic vibration apparatus and the machine tool, and starting a high-speed precision interrupted ultrasonic vibration cutting process. High-speed precision interrupted ultrasonic vibration cutting is able to be realized through the above steps during machining of difficult-to-machine materials in aviation and aerospace fields.

Abstract: The present invention relates to a steerable sheath tube (100) including a tube body (110), a traction mechanism (120) and a fixing and connecting mechanism (130). The traction mechanism (120) includes an anchor ring (121) and a traction wire (122). The anchor ring (121) is coaxially embedded in a distal elastic segment (111) of the tube body (110). The traction wire (122) is arranged in a side wall of the tube body (110), and extends along the axial direction of the tube body (110). The traction wire (122) includes a first segment and a second segment connected to each other, wherein the first segment is connected to the fixing and connecting mechanism (130) near a proximal end of the tube body (110), and the second segment hooks the anchor ring (121).

Abstract: The present invention provides an aortic arch intraoperative stent, wherein the aortic arch intraoperative stent comprising a main body (17) and one to three branches (5, 6, 7), The aortic arch intraoperative stent connects several circular waveform rings together via a cover membrane (25) to form the main body (17) and the branches (5, 6, 7), wherein each circular waveform ring comprises a circular elastic wire formed through head-to-tail connection. In addition, the present invention also provides a manufacturing method for the aortic arch intraoperative stent, comprising the following steps of: providing a cover membrane mandrel (40); making an inner membrane; assembling circular waveform rings; making an outer membrane; suturing a proximal fabric (12); and suturing a distal fabric (13).

Abstract: The invention discloses an absorbable iron alloy stent, comprising an iron alloy substrate and a degradable polymer in contact with the surface of the substrate, in which the degradable polymer has a weight average molecular weight of more than or equal to 20,000 and less than or equal to 1,000,000 and a polydispersity index of more than 1.0 and less than or equal to 50. After the iron alloy stent is implanted into the body, the degradable polymer degrades to produce a carboxyl group. After the degradable stent is implanted into the human body, the effects of oxygen-consuming corrosion enable the stent both to mainly function as a mechanical support and then to degrade gradually, and the amount of hydrogen produced in the degradation process does not reach the level that can lead to a risk of air embolism.

Abstract: The invention discloses an absorbable iron-based alloy stent, comprising an iron-based alloy substrate and a degradable polyester in contact with the surface of the substrate, in which the degradable polyester has a weight average molecular weight of between 20,000 and 1,000,000 and a polydispersity index of between 1.2 and 30. With the degradable polyester, the iron-based alloy is capable of corroding rapidly and controllably within a predetermined period. Following implantation into the human body, the degradable stent serves as a mechanical support at early stage, then gradually degrading and being metabolized and absorbed by the human body. During the process of degradation, minimal or no solid product is produced. Ultimately, the configuration of the lumen with an implanted stent as well as the systolic and diastolic functions thereof return to their natural states.

Abstract: Disclosed is a manufacturing method of an iron-based alloy medical apparatus, comprising: nitriding the iron-based alloy preformed unit at 350-550° C. for 30 100 minutes; and ion etching the iron-based alloy preformed unit with an ion etching time of 80-110% of the nitriding time, Ion nitriding and ion etching can be performed in situ in the same equipment using this manufacture method with high production efficiency, and in the ion nitriding and ion etching process, nitrogen atoms continuously permeate the preformed unit, making the time it takes for he medical apparatus to be absorbed by the human body and both the hardness and strength of the instrument surface achieve requirements.

Abstract: A left atrial appendage occluder comprises an elastic closure disc, and a supporting structure connecting with the closure disc and being located on one side of the closure disc, with the supporting structure comprising a central end connecting with the closure disc and a plurality of interconnected and bent struts, wherein at least one anchoring thorn is set near the end of at least one strut with the anchoring thorn toward the closure disc. The left atrial appendage occluder has a stable structure, a good positioning and sealing effect on the cavity wall in the left atrial appendage, and it is easy to position repeatedly; it can also be recycled before separating from a conveyor. When in surgical operation, the left atrial appendage occluder can select the position area based on the actual shape and size of the patient's left atrial appendage, so the surgical risk is lowered.