Patents by Inventor Dieter Lenke

Dieter Lenke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4463007
    Abstract: 1,2,4-Triazolo[1,5-c]-quinazolinones of the general formula I ##STR1## and their pharmaceutically tolerated salts, processes for their preparation and pharmaceutical formulations which contain these compounds and are useful drugs in the treatment of allergic disorders.
    Type: Grant
    Filed: November 15, 1982
    Date of Patent: July 31, 1984
    Assignee: BASF Aktiengesellschaft
    Inventors: Rainer Schlecker, Ludwig Friedrich, Dieter Lenke
  • Patent number: 4447610
    Abstract: 10-Substituted 5-cyanomethylene-dibenzo[a,d]-cycloheptenes, their pure cis- and trans-isomers, their N-oxides and their pharmaceutically tolerated addition salts with acids, processes for their preparation, therapeutic agents containing these compounds and their use as drugs, especially as sedatives, hypnotics or tranquilizers.
    Type: Grant
    Filed: February 25, 1981
    Date of Patent: May 8, 1984
    Assignee: BASF Aktiengesellschaft
    Inventors: Gerd Steiner, Hans P. Hofmann, Horst Kreiskott, Hans-Juergen Teschendorf, Dieter Lenke
  • Patent number: 4428950
    Abstract: Novel (hetarylphenoxy)-(phenylpiperazinyl)-propanols of the formula ##STR1## where R.sup.1 is hydrogen, amino or alkyl of 1 to 4 carbon atoms, R.sup.2 is hydrogen, halogen, alkyl of 1 to 4 carbon atoms or alkoxy where alkyl is of 1 to 3 carbon atoms, the phenyl ring can be monosubstituted or disubstituted by R.sup.2, and the heterocyclic structure Het. is pyrimidinyl, triazol-1-yl, imidazol-1-yl, pyrazol-3-yl or isoxazol-3-yl, and their physiologically tolerated addition salts with acids, processes for their preparation, and pharmaceutical formulations which contain these compounds and exhibit predominantly hypotensive, sedative, neuroleptic and broncholytic properties.
    Type: Grant
    Filed: January 15, 1982
    Date of Patent: January 31, 1984
    Assignee: BASF Aktiengesellschaft
    Inventors: Albrecht Franke, Gerd Steiner, Peter C. Thieme, Dieter Lenke, Josef Gries, Hans-Juergen Teschendorf
  • Patent number: 4415571
    Abstract: Novel 6-phenyl-4,5-dihydro-3(2H)-pyridazinones which are substituted in the p-position of the phenyl ring by a carbamate or thiocarbamate group, processes for their preparation, pharmaceutical formulations containing these compounds, and their use as drugs in thrombo-embolic disorders, and as anti-hypertensives.
    Type: Grant
    Filed: June 9, 1981
    Date of Patent: November 15, 1983
    Assignee: BASF Aktiengesellschaft
    Inventors: Marco Thyes, Albrecht Franke, Horst Koenig, Dieter Lenke, Hans D. Lehmann, Josef Gries
  • Patent number: 4410529
    Abstract: Novel 6-(p-acylaminophenyl)-4,5-dihydro-3(2H)-pyridazinones, whose acyl radical is derived from a cycloalkylcarboxylic acid, processes for their preparation, pharmaceutical formulations containing these compounds, and their use as drugs in thrombo-embolic disorders and as anti-hypertensives.
    Type: Grant
    Filed: June 12, 1981
    Date of Patent: October 18, 1983
    Assignee: BASF Aktiengesellschaft
    Inventors: Marco Thyes, Horst Koenig, Dieter Lenke, Hans D. Lehmann, Josef Gries
  • Patent number: 4407810
    Abstract: Novel 2-substituted thiazol-2-yl-oxamic acid esters, processes for their preparation, and therapeutic agents which contain these compounds and are useful in the treatment of allergic disorders.
    Type: Grant
    Filed: July 13, 1981
    Date of Patent: October 4, 1983
    Assignee: BASF Aktiengesellschaft
    Inventors: Heinz Eilingsfeld, Peter Neumann, Guenther Seybold, Dieter Lenke, Ludwig Friedrich
  • Patent number: 4399137
    Abstract: 6-Imidazol-1-yl-3-hydrazino-pyridazines, in which the imidazole ring is unsubstituted or is substituted by halogen or alkyl, their physiologically tolerated addition salts with acids, processes for their preparation and their use as drugs in the treatment of hypertonia.
    Type: Grant
    Filed: December 14, 1981
    Date of Patent: August 16, 1983
    Assignee: BASF Aktiengesellschaft
    Inventors: Gerd Steiner, Josef Gries, Dieter Lenke
  • Patent number: 4399139
    Abstract: Novel 5,6-dihydro-11-alkylene-morphanthridin-6-ones of the formula ##STR1## where R.sup.1, R.sup.2, R.sup.3 and R.sup.4 have the meanings given in the description, their preparation and their use.The novel compounds are particularly useful in the treatment of gastric and duodenal ulcers.
    Type: Grant
    Filed: March 19, 1982
    Date of Patent: August 16, 1983
    Assignee: BASF Aktiengesellschaft
    Inventors: Gerd Steiner, Ludwig Friedrich, Dieter Lenke
  • Patent number: 4389403
    Abstract: 1-Aroyl-2-phenylamino-2-imidazolines of the general formula ##STR1## where R.sup.1 and R.sup.2 are identical or different and each is chlorine, bromine, fluorine, methyl, ethyl, methoxy, trifluoromethyl or cyano,R.sup.3 has the meanings given for R.sup.1 and R.sup.2 or is hydrogen andAr is an unsubstituted or substituted monocyclic or bicyclic heteroaromatic radical containing 1, 2 or 3 nitrogen and/or oxygen and/or sulfur atoms, their salts with physiologically tolerated acids, their preparation, and drugs containing these compounds.The compounds have, inter alia, a blood pressure-reducing action.
    Type: Grant
    Filed: March 3, 1981
    Date of Patent: June 21, 1983
    Assignee: BASF Aktiengesellschaft
    Inventors: Hans-Joachim May, Dieter Lenke, Josef Gries, Hans-Juergen Teschendorf, Wolfgang Worstmann
  • Patent number: 4388237
    Abstract: 6-Substituted 11-alkylene-morphanthridines, also referred to as 11-alkylene-dibenzo[b,e]-azepines, their pure cis- and trans-isomers, processes for their preparation, and therapeutic agents containing these compounds, which may be used as drugs, in particular neuroleptics, sedatives, hypnotics, analgesics, antidepressants or agents for treating Parkinson's syndrome.
    Type: Grant
    Filed: May 7, 1980
    Date of Patent: June 14, 1983
    Assignee: BASF Aktiengesellschaft
    Inventors: Gerd Steiner, Albrecht Franke, Dieter Lenke, Hans-Juegen Teschendorf, Wolfgang Worstmann, Horst Kreiskott
  • Patent number: 4376771
    Abstract: 6-(p-Acylaminophenyl)-4,5-dihydropyridaz-3-ones of the formula I ##STR1## where R.sup.1 is hydrogen or alkyl of 1 to 3 carbon atoms and R.sup.2, if R.sup.1 is hydrogen, is halogen-substituted alkyl of 3 to 6 carbon atoms or .beta.-haloethyl or, if R.sup.1 is alkyl of 1 to 3 carbon atoms, is halogen-substituted alkyl of 1 to 6 carbon atoms, their manufacture, and therapeutic agents which contain, as the active ingredient, a compound of the formula I, where R.sup.2 may also be halomethyl or .alpha.-haloethyl if R.sup.1 is hydrogen. These compounds may be used as anti-hypertensive agents and for the prophylaxis and therapy of thromboembolic disorders.
    Type: Grant
    Filed: January 14, 1981
    Date of Patent: March 15, 1983
    Assignee: BASF Aktiengesellschaft
    Inventors: Rolf Lebkuecher, Marco Thyes, Horst Koenig, Hans D. Lehmann, Josef Gries, Dieter Lenke, Johannes Kunze
  • Patent number: 4353904
    Abstract: Novel phenylpiperazinylpropanols of 1,3,4-oxadiazolylphenols and their physiologically tolerated addition salts with acids, processes for their preparation, and pharmaceutical formulations which contain these compounds and are useful in the treatment of hypertonia.
    Type: Grant
    Filed: January 26, 1981
    Date of Patent: October 12, 1982
    Assignee: BASF Aktiengesellschaft
    Inventors: Peter C. Thieme, Albrecht Franke, Dieter Lenke, Hans D. Lehmann, Josef Gries
  • Patent number: 4353917
    Abstract: Novel aminopropanol derivatives of 2-methyl-5-(2-hydroxystyryl)-1,3,4-thiadiazole and their addition salts with acids, their preparation, pharmaceutical formulations containing these compounds, and their use as drugs in the treatment of coronary heart disease, hypertonia and cardiac arrhythmias.
    Type: Grant
    Filed: October 23, 1980
    Date of Patent: October 12, 1982
    Assignee: BASF Aktiengesellschaft
    Inventors: Fritz-Frieder Frickel, Peter C. Thieme, Albrecht Franke, Helmut Hagen, Dieter Lenke, Josef Gries
  • Patent number: 4340595
    Abstract: Aminopropanol derivatives of 6-hydroxy-2,3,4,5-tetrahydro-1-H-1-benzazepin-2-one of the formula ##STR1## where R is alkyl of 1 to 6 carbon atoms, which is unsubstituted or substituted by hydroxyl or by alkoxy of 1 to 3 carbon atoms, or is alkenyl or alkynyl of 3 to 6 carbon atoms or is cycloalkyl of 3 to 7 carbon atoms in the ring, and their physiologically acceptable addition salts with acids, their preparation and pharmaceutical formulations, containing the said compounds, which because of their .beta.-sympatholytic action can be used as cardiac and circulatory drugs.
    Type: Grant
    Filed: January 19, 1981
    Date of Patent: July 20, 1982
    Assignee: BASF Aktiengesellschaft
    Inventors: Albrecht Franke, Dieter Lenke, Josef Gries, Hans D. Lehmann
  • Patent number: 4336263
    Abstract: The invention relates to novel 1,4-cycloalkano-oxazepines of the general formula ##STR1## where R.sup.1 is hydrogen, hydroxyl or alkoxy or acyloxy of 1 to 4 carbon atoms, R.sup.2 is a hydrocarbon radical of 1 to 3 carbon atoms, n is 1, 2 or 3 and x is 0 or 1, and of its salts with physiologically acceptable acids; processes for their preparation, and their use in therapy.The novel substances are suitable for the pharmacotherapy of pains of various origins.
    Type: Grant
    Filed: June 26, 1980
    Date of Patent: June 22, 1982
    Assignee: BASF Aktiengesellschaft
    Inventors: Hans J. Treiber, Dieter Lenke, Wolfgang Worstmann
  • Patent number: 4335138
    Abstract: Novel carbamates derived from substituted cyclic .beta.-keto-alcohols, their preparation, and pharmaceutical formulations which contain these compounds and which may be used as hypnotics in the treatment of sleep disturbance and as sedatives.
    Type: Grant
    Filed: September 15, 1980
    Date of Patent: June 15, 1982
    Assignee: BASF Aktiengesellschaft
    Inventors: Walter-Wielant Wiersdorff, Karl-Heinz Geiss, Harald Weifenbach, Wolfgang Worstmann, Dieter Lenke, Rolf Kretzschmar
  • Patent number: 4329352
    Abstract: Substituted piperidino-alkyl ethers of 3-hydroxy-thiophene-2-carboxylic acid esters and their physiologically tolerated addition salts with acids, processes for their preparation, and pharmaceutical formulations which contain these compounds and which may be used in the treatment of cardiac arrhythmias.
    Type: Grant
    Filed: December 3, 1980
    Date of Patent: May 11, 1982
    Assignee: BASF Aktiengesellschaft
    Inventors: Fritz-Frieder Frickel, Gerda von Philipsborn, Claus D. Mueller, Dieter Lenke
  • Patent number: 4315939
    Abstract: Substituted piperidinoalkyl ethers of 4,5-dialkyl-3-hydroxy-pyrrole-2-carboxylic acid esters and their physiologically tolerated addition salts with acids, processes for their preparation and pharmaceutical formulations which contain these compounds and are useful in the treatment of cardiac arrhythmias.
    Type: Grant
    Filed: October 6, 1980
    Date of Patent: February 16, 1982
    Assignee: BASF Aktiengesellschaft
    Inventors: Fritz-Frieder Frickel, Albrecht Franke, Gerda Von Philipsborn, Claus D. Mueller, Dieter Lenke
  • Patent number: 4305951
    Abstract: Novel aminopropanol derivatives of 5-(2-hydroxystyryl)-isoxazole and their addition salts with acids, their preparation, pharmaceutical formulations containing these compounds, and their use in the treatment of hypertonia, coronary heart disease and cardiac arrhythmias.
    Type: Grant
    Filed: October 23, 1980
    Date of Patent: December 15, 1981
    Assignee: BASF Aktiengesellschaft
    Inventors: Fritz-Frieder Frickel, Peter C. Thieme, Albrecht Franke, Hans Theobald, Dieter Lenke, Josef Gries
  • Patent number: 4305950
    Abstract: Alkylaminopropanol derivatives of 2-methyl-5-(2-hydroxystyryl)-1,3,4-thiadiazole and their addition salts with acids, their preparation, and pharmaceutical formulations, containing these compounds, which may be used for the treatment of coronary diseases of the heart, of hypertonia and of cardiac arrhythmias.
    Type: Grant
    Filed: February 25, 1980
    Date of Patent: December 15, 1981
    Assignee: BASF Aktiengesellschaft
    Inventors: Peter C. Thieme, Fritz-Frieder Frickel, Helmut Hagen, Albrecht Franke, Dieter Lenke, Josef Gries