Patents by Inventor Dieter Lenke

Dieter Lenke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4288449
    Abstract: Compounds of the formula 1 ##STR1## where R.sup.1 is a saturated, unsubstituted or substituted aliphatic radical of 1 to 8 carbon atoms, an unsaturated alkyl radical of 2 to 8 carbon atoms, a cycloalkyl radical of 3 to 7 carbon atoms in the ring or an alkyl radical of 1 to 4 carbon atoms which is substituted by phenyl or by a 5- or 6-membered aromatic heterocyclic ring containing an N, O or S atom, the phenyl ring or the heterocyclic ring itself being unsubstituted, monosubstituted or polysubstituted, andR.sup.2 is hydrogen orR.sup.1 and R.sup.2 together with the nitrogen are a 4-membered to 6-membered cycloaliphatic saturated heterocyclic ring,R.sup.3 is hydrogen or alkyl of 1 to 5 carbon atoms,R.sup.4 and R.sup.
    Type: Grant
    Filed: May 28, 1980
    Date of Patent: September 8, 1981
    Assignee: BASF Aktiengesellschaft
    Inventors: Jens-Uwe Bliesener, Karl-Heinz Geiss, Dieter Lenke, Claus D. Mueller
  • Patent number: 4271163
    Abstract: 2-Aryl-3,4-diaza-bicyclo-[4.1.0]hept-2-en-5-ones, substituted in the phenyl ring, of the general formula ##STR1## their preparation, and therapeutic agents, containing these compounds, which may be used for the treatment of hypertension or of thrombo-embolic disorders.
    Type: Grant
    Filed: November 30, 1979
    Date of Patent: June 2, 1981
    Assignee: BASF Aktiengesellschaft
    Inventors: Marco Thyes, Josef Gries, Hans D. Lehmann, Dieter Lenke, Johannes Kunze
  • Patent number: 4269833
    Abstract: Novel hexahydro-1,4-oxazepines of the general formula I ##STR1## where R.sup.1 is hydrogen, or alkyl or acyl each of 1 to 4 carbon atoms,R.sup.2 is alkyl of 1 to 4 carbon atoms andR.sup.3 and R.sup.4 are identical or different and each is hydrogen or methyl, and their salts with physiologically acceptable acids, processes for their preparation, drugs which contain these compounds, and their use in therapy.The compounds may be used for the pharmacotherapy of pain of various geneses.
    Type: Grant
    Filed: December 31, 1979
    Date of Patent: May 26, 1981
    Assignee: BASF Aktiengesellschaft
    Inventors: Hans J. Treiber, Dieter Lenke, Wolfgang Worstmann
  • Patent number: 4267187
    Abstract: Alkylaminopropanol derivatives of 2-(o-hydroxyphenyl)-pyrrole of the formula (I) ##STR1## where R is hydrogen or is alkyl of 1 to 8 carbon atoms which is unsubstituted or substituted by hydroxyl, alkoxy of 1 to 3 carbons atoms or cycloalkyl of 3 to 8 carbon atoms in the ring, or is alkenyl or alkynyl of 2 to 8 carbon atoms or is cycloalkyl or cycloalkenyl of 3 to 8 carbon atoms in the ring, the cycloalkyl rings being unsubstituted or monosubstituted or disubstituted by alkyl or 1 to 3 carbon atoms, and their physiologically acceptable acid addition salts, processes for their preparation, and pharmaceutical formulations which contain the said compounds and may be used in the treatment of cardiac and circulatory disorders.
    Type: Grant
    Filed: August 8, 1979
    Date of Patent: May 12, 1981
    Assignee: BASF Aktiengesellschaft
    Inventors: Fritz-Frieder Frickel, Albrecht Franke, Horst Koenig, Hans-Dieter Lenke, Josef Gries
  • Patent number: 4251539
    Abstract: Alkylamino-propanol derivatives of 3-alkyl-5-(2-hydroxystyryl)-isoxazole, of the general formula ##STR1## where R is hydrogen, alkyl of 1 to 8 carbon atoms, which is unsubstituted or substituted by hydroxyl, alkoxy of 1 to 3 carbon atoms or cycloalkyl with 3 to 8 carbon atoms in the ring, alkenyl or alkynyl of 2 to 8 carbon atoms, or cycloalkyl with 3 to 8 carbon atoms in the ring, the cycloalkyl rings being unsubstituted or mono- or di-substituted by alkyl of 1 to 3 carbon atoms, and R' is alkyl of 1 to 4 carbon atoms, and their addition salts with physiologically acceptable acids, their preparation, and pharmaceutical formulations which contain these compounds and which can be used as valuable drugs in the treatment of hypertonia, coronary diseases of the heart and cardiac arrhythmias.
    Type: Grant
    Filed: April 17, 1979
    Date of Patent: February 17, 1981
    Assignee: BASF Aktiengesellschaft
    Inventors: Peter C. Thieme, Fritz-Frieder Frickel, Hans Theobald, Albrecht Franke, Dieter Lenke, Josef Gries
  • Patent number: 4237278
    Abstract: Novel alkylaminopropanol derivatives of 2-methyl-5-(2-hydroxystyryl)-1,3,4-thiadiazole and their addition salts with acids, their preparation, and pharmaceutical formulations, containing these compounds, which may be used for the treatment of coronary diseases of the heart, of hypertonia and of cardiac arrhythmias.
    Type: Grant
    Filed: April 17, 1979
    Date of Patent: December 2, 1980
    Assignee: BASF Aktiengesellschaft
    Inventors: Peter C. Thieme, Fritz-Frieder Frickel, Helmut Hagen, Albrecht Franke, Dieter Lenke, Josef Gries
  • Patent number: 4206217
    Abstract: 3-[4-(1,3-Diazacyclo-2-yl)]-1,2-benzisothiazoles, their addition salts with acids, their manufacture, and pharmaceutical formulations which contain these compounds as active ingredients and which may be used for the pharmacotherapy of cardiac arrhythmias.
    Type: Grant
    Filed: July 28, 1978
    Date of Patent: June 3, 1980
    Assignee: BASF Aktiengesellschaft
    Inventors: Helmut Hagen, Dieter Lenke, Gerda von Philipsborn
  • Patent number: 4206117
    Abstract: New pyridinyl aminoalkyl ethers, their N-oxides and their physiologically acceptable addition salts with acids, processes for their preparation and pharmaceutical formulations which contain these compounds and are useful in the treatment of cardiac arrhythmias.
    Type: Grant
    Filed: March 10, 1978
    Date of Patent: June 3, 1980
    Assignee: BASF Aktiengesellschaft
    Inventors: Gerda Von Philipsborn, Walter Boell, Dieter Lenke
  • Patent number: 4168317
    Abstract: New aminopropanol derivatives of 4-hydroxy-1,2-benzisothiazole and their addition salts with acids, their preparation, and pharmaceutical formulations which contain the said compounds and may be used for the treatment and prophylaxis of cardiac and circulatory disorders.
    Type: Grant
    Filed: January 30, 1978
    Date of Patent: September 18, 1979
    Assignee: BASF Aktiengesellschaft
    Inventors: Fritz-Frieder Frickel, Helmut Hagen, Ulrich Ohnsorge, Albrecht Franke, Dieter Lenke, Josef Gries, Hans D. Lehmann
  • Patent number: 4124716
    Abstract: Process for the treatment of spasmodic conditions in humans by administering a compound of the general formula ##STR1## or a pharmacologically acceptable acid addition salt thereof to a human suffering from such conditions.
    Type: Grant
    Filed: October 14, 1977
    Date of Patent: November 7, 1978
    Assignee: Asta-werke Aktiengesellschaft
    Inventors: Peter Emig, Hans Pohle, Gerhard Scheffler, Norbert Brock, Hans-Dieter Lenke, Jorg Pohl
  • Patent number: 4065501
    Abstract: The present invention is related to new basic enol ethers having the general formula ##STR1## and to the pharmacologically acceptable acid addition salts thereof. The invention is further related to process for the treatment of spasmodic conditions in humans by administering a compound of the above general formula or a pharmacologically acceptable acid addition salt thereof to a human suffering from such conditions.
    Type: Grant
    Filed: March 12, 1975
    Date of Patent: December 27, 1977
    Assignee: Asta-Werke Aktiengesellschaft
    Inventors: Peter Emig, Hans Pohle, Gerhard Scheffler, Norbert Brock, Hans-Dieter Lenke, Jorg Pohl
  • Patent number: 4042588
    Abstract: 1,2,4-Dihydrotriazine-4-oxide-spiro-(3,1')-[oximino-(2')-cycloalkanes] are manufactured by reaction of oximinocycloalk-1-enes, substituted in the 1-position, with hydrazine. The products, especially the triazine derivative described in Example 1, possess antiphlogistic properties and are starting materials for the manufacture of dyes and pharmaceuticals.
    Type: Grant
    Filed: June 1, 1976
    Date of Patent: August 16, 1977
    Assignee: BASF Aktiengesellschaft
    Inventors: Hans-Martin Weitz, Rolf Fischer, Dieter Lenke
  • Patent number: 4042587
    Abstract: New 1,2,4-dihydrotriazine-4-oxides and a new process for the manufacture of 1,2,4-dihydrotriazine-4-oxides by reaction of oximino-cycloalk-1-enes, which are substituted in the 1-position, with hydrazine and ketones. The compounds I are pesticides and starting materials for the manufacture of pesticides.
    Type: Grant
    Filed: June 1, 1976
    Date of Patent: August 16, 1977
    Assignee: BASF Aktiengesellschaft
    Inventors: Hans-Martin Weitz, Rolf Fischer, Dieter Lenke